GO:0004376
JSON
glycolipid mannosyltransferase activity
Molecular Function
Definition (GO:0004376 GONUTS page)
Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.
Secondary IDs
GO:0004580
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
glycolipid mannosyl transferase activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004376
Child Term | Relationship to GO:0004376 |
---|---|
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
|
is_a |
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
|
is_a |
glycolipid 1,4-alpha-mannosyltransferase activity
|
is_a |
glycolipid 1,6-alpha-mannosyltransferase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016757 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A6KJI3 | 10116 | A6KJI3_RAT | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D6WQD5 | 7070 | D6WQD5_TRICA | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q6AYL7 | 10116 | Q6AYL7_RAT | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7JRM5 | 7227 | Q7JRM5_DROME | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR007315 | GPI mannosyltransferase 2 |
InterPro | IPR007704 | GPI mannosyltransferase 1 |
Reactome | R-HSA-162821 | |
Reactome | R-HSA-162873 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004376 based on ALL annotations
The top 100 of 332 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glycolipid mannosyltransferase activity
|
12,320.77 | 100.00 | 16,083 | 16,083 |
mannosyltransferase complex
|
10,891.05 | 48.81 | 8,387 | 9,488 |
alpha-1,6-mannosyltransferase activity
|
5,453.81 | 37.86 | 11,636 | 26,287 |
alpha-1,4-mannosyltransferase activity
|
12,320.77 | 27.64 | 4,445 | 4,445 |
glycosylphosphatidylinositol-mannosyltransferase I complex
|
9,314.57 | 23.17 | 4,028 | 5,328 |
mannosyltransferase activity
|
1,604.26 | 12.55 | 12,488 | 95,908 |
GPI anchor metabolic process
|
2,203.84 | 11.43 | 3,869 | 21,630 |
GPI anchor biosynthetic process
|
1,263.14 | 10.25 | 16,082 | 156,865 |
endoplasmic reticulum membrane
|
82.13 | 0.66 | 8,435 | 1,265,429 |
glycosyltransferase activity
|
61.04 | 0.50 | 15,736 | 3,176,052 |
Totals | 126363 | 61150056 |
No co-occurrence statistics for GO:0004376 based on MANUAL annotations
The top 13 of 13 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glycolipid mannosyltransferase activity
|
470,511.00 | 100.00 | 3 | 3 |
mannosylation
|
94,102.20 | 14.29 | 1 | 5 |
mannosyltransferase complex
|
4,056.13 | 0.85 | 1 | 116 |
alpha-1,3-mannosyltransferase activity
|
2,940.69 | 0.62 | 1 | 160 |
mannosyltransferase activity
|
1,421.48 | 0.30 | 2 | 662 |
alpha-1,2-mannosyltransferase activity
|
1,278.56 | 0.27 | 1 | 368 |
dolichol-linked oligosaccharide biosynthetic process
|
481.59 | 0.10 | 1 | 977 |
GPI anchor biosynthetic process
|
441.17 | 0.09 | 2 | 2,133 |
lipid droplet
|
284.13 | 0.06 | 1 | 1,656 |
endomembrane system
|
62.60 | 0.01 | 1 | 7,516 |
Totals | 19 | 140136 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Deleted | XREF | reactome:R-HSA-162873 |
2019-04-01 | Added | XREF | Reactome:R-HSA-162821 |
2019-04-01 | Added | XREF | Reactome:R-HSA-162873 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-162821 |
2018-12-11 | Added | XREF | reactome:R-HSA-162873 |
2018-12-11 | Added | XREF | reactome:R-HSA-162821 |
2017-10-08 | Deleted | XREF | EC:2.4.1 |
2016-10-03 | Added | XREF | EC:2.4.1 |
2016-10-03 | Deleted | XREF | EC:2.4.1.- |
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | glycolipid mannosyltransferase activity |
2002-02-06 | Updated | TERM | glycolipid mannosyltransferase |
2001-04-03 | Updated | TERM | glycolipid mannosyltransferase |
2001-03-30 | Added | TERM | glycolipid mannosyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage. |
2007-11-08 | Deleted | SYNONYM | glycolipid mannosyl transferase |
2007-11-08 | Added | SYNONYM | glycolipid mannosyl transferase activity |
2007-08-09 | Deleted | SYNONYM | glycolipid mannosyl transferase |
2007-08-09 | Added | SYNONYM | glycolipid mannosyl transferase |
2004-04-19 | Added | SYNONYM | glycolipid mannosyl transferase |
2004-04-16 | Deleted | SYNONYM | glycolipid mannosyl transferase |
2004-03-09 | Added | DEFINITION | Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage. |
2002-11-20 | Added | SYNONYM | glycolipid mannosyl transferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0000030 (mannosyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Deleted | XREF | reactome:R-HSA-162873 |
2019-04-01 | Added | XREF | Reactome:R-HSA-162821 |
2019-04-01 | Added | XREF | Reactome:R-HSA-162873 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-162821 |
2018-12-11 | Added | XREF | reactome:R-HSA-162873 |
2018-12-11 | Added | XREF | reactome:R-HSA-162821 |
2017-10-08 | Deleted | XREF | EC:2.4.1 |
2016-10-03 | Added | XREF | EC:2.4.1 |
2016-10-03 | Deleted | XREF | EC:2.4.1.- |
2001-03-30 | Added | XREF | EC:2.4.1.- |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-11-20 | Added | SECONDARY | GO:0004580 (glycolipid mannosyl transferase) |
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