This term is obsolete.

GO:0004376 JSON

glycolipid mannosyltransferase activity

Molecular Function

Definition (GO:0004376 GONUTS page)

Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.

Secondary IDs

GO:0004580

32,355 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
glycolipid mannosyl transferase activity exact

Ancestor Chart

Ancestor chart for GO:0004376
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004376

Child Term Relationship to
GO:0004376
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
is_a
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
is_a
glycolipid 1,4-alpha-mannosyltransferase activity
is_a
glycolipid 1,6-alpha-mannosyltransferase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016757 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A6KJI3 10116 A6KJI3_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D6WQD5 7070 D6WQD5_TRICA GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q6AYL7 10116 Q6AYL7_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7JRM5 7227 Q7JRM5_DROME GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
InterPro IPR007315 GPI mannosyltransferase 2
InterPro IPR007704 GPI mannosyltransferase 1
Reactome R-HSA-162821
Reactome R-HSA-162873

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004376 based on ALL annotations
The top 100 of 332 co-occurring terms
Co-occurring Term PR S% #Together #Compared
glycolipid mannosyltransferase activity
12,320.77 100.00 16,083 16,083
mannosyltransferase complex
10,891.05 48.81 8,387 9,488
alpha-1,6-mannosyltransferase activity
5,453.81 37.86 11,636 26,287
alpha-1,4-mannosyltransferase activity
12,320.77 27.64 4,445 4,445
glycosylphosphatidylinositol-mannosyltransferase I complex
9,314.57 23.17 4,028 5,328
mannosyltransferase activity
1,604.26 12.55 12,488 95,908
GPI anchor metabolic process
2,203.84 11.43 3,869 21,630
GPI anchor biosynthetic process
1,263.14 10.25 16,082 156,865
endoplasmic reticulum membrane
82.13 0.66 8,435 1,265,429
glycosyltransferase activity
61.04 0.50 15,736 3,176,052
Totals 126363 61150056
No co-occurrence statistics for GO:0004376 based on MANUAL annotations
The top 13 of 13 co-occurring terms
Co-occurring Term PR S% #Together #Compared
glycolipid mannosyltransferase activity
470,511.00 100.00 3 3
mannosylation
94,102.20 14.29 1 5
mannosyltransferase complex
4,056.13 0.85 1 116
alpha-1,3-mannosyltransferase activity
2,940.69 0.62 1 160
mannosyltransferase activity
1,421.48 0.30 2 662
alpha-1,2-mannosyltransferase activity
1,278.56 0.27 1 368
dolichol-linked oligosaccharide biosynthetic process
481.59 0.10 1 977
GPI anchor biosynthetic process
441.17 0.09 2 2,133
lipid droplet
284.13 0.06 1 1,656
endomembrane system
62.60 0.01 1 7,516
Totals 19 140136

Change Log

Timestamp Action Category Detail
2019-04-01 Deleted XREF reactome:R-HSA-162873
2019-04-01 Added XREF Reactome:R-HSA-162821
2019-04-01 Added XREF Reactome:R-HSA-162873
2019-04-01 Deleted XREF reactome:R-HSA-162821
2018-12-11 Added XREF reactome:R-HSA-162873
2018-12-11 Added XREF reactome:R-HSA-162821
2017-10-08 Deleted XREF EC:2.4.1
2016-10-03 Added XREF EC:2.4.1
2016-10-03 Deleted XREF EC:2.4.1.-
2008-05-13 Added DEFINITION Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.
Timestamp Action Category Detail
2003-03-19 Updated TERM glycolipid mannosyltransferase activity
2002-02-06 Updated TERM glycolipid mannosyltransferase
2001-04-03 Updated TERM glycolipid mannosyltransferase
2001-03-30 Added TERM glycolipid mannosyltransferase
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.
2007-11-08 Deleted SYNONYM glycolipid mannosyl transferase
2007-11-08 Added SYNONYM glycolipid mannosyl transferase activity
2007-08-09 Deleted SYNONYM glycolipid mannosyl transferase
2007-08-09 Added SYNONYM glycolipid mannosyl transferase
2004-04-19 Added SYNONYM glycolipid mannosyl transferase
2004-04-16 Deleted SYNONYM glycolipid mannosyl transferase
2004-03-09 Added DEFINITION Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.
2002-11-20 Added SYNONYM glycolipid mannosyl transferase
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0000030 (mannosyltransferase activity)
Timestamp Action Category Detail
2019-04-01 Deleted XREF reactome:R-HSA-162873
2019-04-01 Added XREF Reactome:R-HSA-162821
2019-04-01 Added XREF Reactome:R-HSA-162873
2019-04-01 Deleted XREF reactome:R-HSA-162821
2018-12-11 Added XREF reactome:R-HSA-162873
2018-12-11 Added XREF reactome:R-HSA-162821
2017-10-08 Deleted XREF EC:2.4.1
2016-10-03 Added XREF EC:2.4.1
2016-10-03 Deleted XREF EC:2.4.1.-
2001-03-30 Added XREF EC:2.4.1.-
Timestamp Action Category Detail
2002-11-20 Added SECONDARY GO:0004580 (glycolipid mannosyl transferase)
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