GO:0004533
JSON
exoribonuclease H activity
Molecular Function
Definition (GO:0004533 GONUTS page)
Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
retroviral reverse transcriptase RNaseH | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A0B4KFF6 | 7227 | A0A0B4KFF6_DROME | GO:0004518 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25392983 | |
NOT-qualified manual | protein | A0A0G2K5A0 | 10116 | A0A0G2K5A0_RAT | GO:0004532 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K5G5 | 10116 | A0A0G2K5G5_RAT | GO:0004527 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y5D3 | 10116 | A0A8I5Y5D3_RAT | GO:0004532 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZNY7 | 10116 | A0A8I5ZNY7_RAT | GO:0004532 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A3V5 | 10116 | A0A8I6A3V5_RAT | GO:0004540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A842 | 10116 | A0A8I6A842_RAT | GO:0004532 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AAC4 | 10116 | A0A8I6AAC4_RAT | GO:0004532 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AB24 | 10116 | A0A8I6AB24_RAT | GO:0004532 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6ACW3 | 10116 | A0A8I6ACW3_RAT | GO:0004540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 3.1.13.2 | |
MetaCyc | 3.1.13.2-RXN |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004533 based on ALL annotations
The top 74 of 74 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
exoribonuclease H activity
|
8,047.67 | 100.00 | 24,223 | 24,223 |
RNA stem-loop binding
|
1,115.03 | 13.85 | 24,218 | 174,792 |
telomerase activity
|
1,053.67 | 13.07 | 23,940 | 182,847 |
RNA-DNA hybrid ribonuclease activity
|
739.87 | 9.18 | 23,853 | 259,451 |
viral genome integration into host DNA
|
440.83 | 5.48 | 24,221 | 442,169 |
establishment of integrated proviral latency
|
440.83 | 5.48 | 24,221 | 442,173 |
viral nucleocapsid
|
340.91 | 4.23 | 23,925 | 564,780 |
aspartic-type endopeptidase activity
|
283.18 | 3.52 | 24,200 | 687,742 |
RNA-templated DNA biosynthetic process
|
281.40 | 3.50 | 24,221 | 692,691 |
RNA-directed DNA polymerase activity
|
281.22 | 3.49 | 24,221 | 693,133 |
Totals | 462721 | 156376385 |
No co-occurrence statistics for GO:0004533 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Totals | 0 | 0 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2013-10-30 | Added | RELATION | has part GO:0001171 (reverse transcription) |
2008-05-13 | Added | DEFINITION | Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions. |
2008-04-01 | Updated | RELATION | is a GO:0016896 (RNA exonuclease activity, producing 5'-phosphomonoesters) |
2007-11-08 | Added | SYNONYM | retroviral reverse transcriptase RNaseH |
2003-10-27 | Added | XREF | MetaCyc:3.1.13.2-RXN |
2003-03-19 | Updated | TERM | exoribonuclease H activity |
2002-11-27 | Updated | DEFINITION | Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions. |
2002-02-06 | Updated | TERM | exoribonuclease H |
2001-08-06 | Added | DEFINITION | Enzyme that catalyzes exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5'- to 3'- and 3'- to 5'-directions. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | exoribonuclease H activity |
2002-02-06 | Updated | TERM | exoribonuclease H |
2001-04-03 | Updated | TERM | exoribonuclease H |
2001-03-30 | Added | TERM | exoribonuclease H |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions. |
2007-11-08 | Added | SYNONYM | retroviral reverse transcriptase RNaseH |
2002-11-27 | Updated | DEFINITION | Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions. |
2001-08-06 | Added | DEFINITION | Enzyme that catalyzes exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5'- to 3'- and 3'- to 5'-directions. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-10-30 | Added | RELATION | has part GO:0001171 (reverse transcription) |
2008-04-01 | Updated | RELATION | is a GO:0016896 (RNA exonuclease activity, producing 5'-phosphomonoesters) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-10-27 | Added | XREF | MetaCyc:3.1.13.2-RXN |
2001-03-30 | Added | XREF | EC:3.1.13.2 |
Timestamp | Action | Category | Detail |
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