This term is obsolete.

GO:0004533 JSON

exoribonuclease H activity

Molecular Function

Definition (GO:0004533 GONUTS page)

Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.

24,223 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
retroviral reverse transcriptase RNaseH related

Ancestor Chart

Ancestor chart for GO:0004533
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0B4KFF6 7227 A0A0B4KFF6_DROME GO:0004518 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25392983
NOT-qualified manual protein A0A0G2K5A0 10116 A0A0G2K5A0_RAT GO:0004532 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K5G5 10116 A0A0G2K5G5_RAT GO:0004527 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5Y5D3 10116 A0A8I5Y5D3_RAT GO:0004532 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZNY7 10116 A0A8I5ZNY7_RAT GO:0004532 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A3V5 10116 A0A8I6A3V5_RAT GO:0004540 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A842 10116 A0A8I6A842_RAT GO:0004532 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AAC4 10116 A0A8I6AAC4_RAT GO:0004532 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AB24 10116 A0A8I6AB24_RAT GO:0004532 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ACW3 10116 A0A8I6ACW3_RAT GO:0004540 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 3.1.13.2
MetaCyc 3.1.13.2-RXN

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004533 based on ALL annotations
The top 74 of 74 co-occurring terms
Co-occurring Term PR S% #Together #Compared
exoribonuclease H activity
8,047.67 100.00 24,223 24,223
RNA stem-loop binding
1,115.03 13.85 24,218 174,792
telomerase activity
1,053.67 13.07 23,940 182,847
RNA-DNA hybrid ribonuclease activity
739.87 9.18 23,853 259,451
viral genome integration into host DNA
440.83 5.48 24,221 442,169
establishment of integrated proviral latency
440.83 5.48 24,221 442,173
viral nucleocapsid
340.91 4.23 23,925 564,780
aspartic-type endopeptidase activity
283.18 3.52 24,200 687,742
RNA-templated DNA biosynthetic process
281.40 3.50 24,221 692,691
RNA-directed DNA polymerase activity
281.22 3.49 24,221 693,133
Totals 462721 156376385
No co-occurrence statistics for GO:0004533 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Totals 0 0

Change Log

Timestamp Action Category Detail
2013-10-30 Added RELATION has part GO:0001171 (reverse transcription)
2008-05-13 Added DEFINITION Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
2008-05-12 Deleted DEFINITION Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
2008-04-01 Updated RELATION is a GO:0016896 (RNA exonuclease activity, producing 5'-phosphomonoesters)
2007-11-08 Added SYNONYM retroviral reverse transcriptase RNaseH
2003-10-27 Added XREF MetaCyc:3.1.13.2-RXN
2003-03-19 Updated TERM exoribonuclease H activity
2002-11-27 Updated DEFINITION Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
2002-02-06 Updated TERM exoribonuclease H
2001-08-06 Added DEFINITION Enzyme that catalyzes exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5'- to 3'- and 3'- to 5'-directions.
Timestamp Action Category Detail
2003-03-19 Updated TERM exoribonuclease H activity
2002-02-06 Updated TERM exoribonuclease H
2001-04-03 Updated TERM exoribonuclease H
2001-03-30 Added TERM exoribonuclease H
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
2008-05-12 Deleted DEFINITION Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
2007-11-08 Added SYNONYM retroviral reverse transcriptase RNaseH
2002-11-27 Updated DEFINITION Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
2001-08-06 Added DEFINITION Enzyme that catalyzes exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5'- to 3'- and 3'- to 5'-directions.
Timestamp Action Category Detail
2013-10-30 Added RELATION has part GO:0001171 (reverse transcription)
2008-04-01 Updated RELATION is a GO:0016896 (RNA exonuclease activity, producing 5'-phosphomonoesters)
Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:3.1.13.2-RXN
2001-03-30 Added XREF EC:3.1.13.2
Timestamp Action Category Detail
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