This term is obsolete.

GO:0004648 JSON

O-phospho-L-serine:2-oxoglutarate aminotransferase activity

Molecular Function

Definition (GO:0004648 GONUTS page)

Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.

Secondary IDs

GO:0004646

36,999 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
3PHP transaminase activity related
3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity related
phosphoserine transaminase activity broad
phosphoserine aminotransferase activity broad
SerC related
PdxC related
phosphohydroxypyruvate transaminase activity related
hydroxypyruvic phosphate--glutamic transaminase activity related
3-phosphoserine aminotransferase activity related
PSAT activity related

Ancestor Chart

Ancestor chart for GO:0004648
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I940 7227 Q8I940_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.6.1.52
InterPro IPR006271 Phosphoserine aminotransferase, Methanosarcina-type
InterPro IPR006272 Phosphoserine aminotransferase, Mycobacterial-type
InterPro IPR022278 Phosphoserine aminotransferase
MetaCyc PSERTRANSAM-RXN
RHEA 14329
Reactome R-HSA-977333

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:16810 2-oxoglutarate(2-)
has_participant CHEBI CHEBI:18110 3-phosphonatooxypyruvate(3-)
has_participant CHEBI CHEBI:29985 L-glutamate(1-)
has_participant CHEBI CHEBI:57524 O-phosphonato-L-serine(2-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004648 based on ALL annotations
The top 100 of 206 co-occurring terms
Co-occurring Term PR S% #Together #Compared
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
5,288.91 100.00 36,858 36,858
L-serine metabolic process
5,175.41 84.03 31,554 32,246
L-serine biosynthetic process
1,888.21 35.61 36,587 102,481
pyridoxine biosynthetic process
962.71 16.15 21,686 119,138
L-serine-pyruvate transaminase activity
1,225.69 15.00 10,998 47,457
glycine biosynthetic process, by transamination of glyoxylate
1,224.62 14.99 11,000 47,507
alanine-glyoxylate transaminase activity
1,142.49 14.33 10,998 50,913
transaminase activity
160.99 3.04 36,771 1,208,015
peroxisome
153.01 2.71 10,998 380,161
pyridoxal phosphate binding
86.42 1.63 28,238 1,728,166
Totals 266116 48685386
No co-occurrence statistics for GO:0004648 based on MANUAL annotations
The top 20 of 20 co-occurring terms
Co-occurring Term PR S% #Together #Compared
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
9,712.77 100.00 133 133
L-serine biosynthetic process
4,176.18 42.86 132 307
pyridoxal phosphate binding
570.57 5.87 130 2,213
serine family amino acid biosynthetic process
2,158.39 1.43 2 9
L-serine metabolic process
396.44 1.11 2 49
lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate
4,856.39 0.75 1 2
purine nucleobase biosynthetic process
462.51 0.65 1 21
pyridoxine biosynthetic process
53.96 0.32 1 180
pyridoxal phosphate biosynthetic process
31.43 0.23 1 309
cytoplasm
6.98 0.07 129 179,389
Totals 554 407624

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM phosphohydroxypyruvate transaminase activity
2020-10-08 Deleted SYNONYM 3PHP transaminase activity
2020-10-08 Deleted SYNONYM phosphohydroxypyruvate transaminase activity
2020-10-08 Deleted SYNONYM hydroxypyruvic phosphate--glutamic transaminase activity
2020-10-08 Deleted SYNONYM PSAT activity
2020-10-08 Deleted SYNONYM L-phosphoserine aminotransferase activity
2020-10-08 Deleted SYNONYM phosphohydroxypyruvic--glutamic transaminase activity
2020-10-08 Deleted SYNONYM 3-phosphoserine aminotransferase activity
2020-10-08 Added SYNONYM PSAT activity
2020-10-08 Added SYNONYM 3PHP transaminase activity
Timestamp Action Category Detail
2009-03-29 Updated TERM O-phospho-L-serine:2-oxoglutarate aminotransferase activity
2003-03-19 Updated TERM phosphoserine transaminase activity
2002-02-06 Updated TERM phosphoserine transaminase
2001-04-03 Updated TERM phosphoserine transaminase
2001-03-30 Added TERM phosphoserine transaminase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM phosphohydroxypyruvate transaminase activity
2020-10-08 Deleted SYNONYM 3PHP transaminase activity
2020-10-08 Deleted SYNONYM phosphohydroxypyruvate transaminase activity
2020-10-08 Deleted SYNONYM hydroxypyruvic phosphate--glutamic transaminase activity
2020-10-08 Deleted SYNONYM PSAT activity
2020-10-08 Deleted SYNONYM L-phosphoserine aminotransferase activity
2020-10-08 Deleted SYNONYM phosphohydroxypyruvic--glutamic transaminase activity
2020-10-08 Deleted SYNONYM 3-phosphoserine aminotransferase activity
2020-10-08 Added SYNONYM PSAT activity
2020-10-08 Added SYNONYM 3PHP transaminase activity
2020-10-08 Added SYNONYM phosphohydroxypyruvic--glutamic transaminase activity
2020-10-08 Added SYNONYM L-phosphoserine aminotransferase activity
2020-10-08 Added SYNONYM hydroxypyruvic phosphate--glutamic transaminase activity
2020-10-08 Added SYNONYM 3-phosphoserine aminotransferase activity
2020-10-08 Added SYNONYM 3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity
2020-10-08 Deleted SYNONYM 3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity
2009-03-29 Added SYNONYM phosphoserine transaminase activity
2009-03-29 Added SYNONYM phosphoserine aminotransferase activity
2009-03-29 Deleted SYNONYM phosphoserine aminotransferase activity
2009-03-29 Deleted SYNONYM O-phospho-L-serine:2-oxoglutarate aminotransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.
2007-11-08 Added SYNONYM PdxC
2007-11-08 Added SYNONYM O-phospho-L-serine:2-oxoglutarate aminotransferase activity
2007-11-08 Added SYNONYM 3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity
2007-11-08 Added SYNONYM SerC
2007-09-06 Added SYNONYM phosphohydroxypyruvate transaminase activity
2007-09-06 Added SYNONYM hydroxypyruvic phosphate--glutamic transaminase activity
2007-09-06 Added SYNONYM PSAT activity
2007-09-06 Added SYNONYM 3PHP transaminase activity
2007-09-06 Added SYNONYM 3-phosphoserine aminotransferase activity
2007-09-06 Added SYNONYM phosphohydroxypyruvic--glutamic transaminase activity
2007-09-06 Added SYNONYM L-phosphoserine aminotransferase activity
2007-08-09 Deleted SYNONYM phosphoserine aminotransferase activity
2007-08-09 Added SYNONYM phosphoserine aminotransferase activity
2004-04-19 Added SYNONYM phosphoserine aminotransferase activity
2004-04-16 Deleted SYNONYM phosphoserine aminotransferase activity
2003-10-27 Added SYNONYM phosphoserine aminotransferase activity
2003-08-21 Deleted SYNONYM phosphoserine aminotransferase activity
2003-06-10 Added SYNONYM phosphoserine aminotransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008483 (transaminase activity)
Timestamp Action Category Detail
2019-04-01 Added XREF Reactome:R-HSA-977333
2019-04-01 Deleted XREF reactome:R-HSA-977333
2018-12-11 Added XREF reactome:R-HSA-977333
2018-07-13 Deleted XREF RHEA:14332
2018-07-13 Added XREF RHEA:14329
2012-09-14 Added XREF RHEA:14332
2003-10-27 Added XREF MetaCyc:PSERTRANSAM-RXN
2001-03-30 Added XREF EC:2.6.1.52
Timestamp Action Category Detail
2003-06-10 Added SECONDARY GO:0004646 (phosphoserine aminotransferase activity)
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