GO:0004648
JSON
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
Molecular Function
Definition (GO:0004648 GONUTS page)
Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.
Secondary IDs
GO:0004646
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
3PHP transaminase activity | related |
3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity | related |
phosphoserine transaminase activity | broad |
phosphoserine aminotransferase activity | broad |
SerC | related |
PdxC | related |
phosphohydroxypyruvate transaminase activity | related |
hydroxypyruvic phosphate--glutamic transaminase activity | related |
3-phosphoserine aminotransferase activity | related |
PSAT activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I940 | 7227 | Q8I940_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.6.1.52 | |
InterPro | IPR006271 | Phosphoserine aminotransferase, Methanosarcina-type |
InterPro | IPR006272 | Phosphoserine aminotransferase, Mycobacterial-type |
InterPro | IPR022278 | Phosphoserine aminotransferase |
MetaCyc | PSERTRANSAM-RXN | |
RHEA | 14329 | |
Reactome | R-HSA-977333 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:16810 | 2-oxoglutarate(2-) |
has_participant | CHEBI | CHEBI:18110 | 3-phosphonatooxypyruvate(3-) |
has_participant | CHEBI | CHEBI:29985 | L-glutamate(1-) |
has_participant | CHEBI | CHEBI:57524 | O-phosphonato-L-serine(2-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004648 based on ALL annotations
The top 100 of 206 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
|
5,288.91 | 100.00 | 36,858 | 36,858 |
L-serine metabolic process
|
5,175.41 | 84.03 | 31,554 | 32,246 |
L-serine biosynthetic process
|
1,888.21 | 35.61 | 36,587 | 102,481 |
pyridoxine biosynthetic process
|
962.71 | 16.15 | 21,686 | 119,138 |
L-serine-pyruvate transaminase activity
|
1,225.69 | 15.00 | 10,998 | 47,457 |
glycine biosynthetic process, by transamination of glyoxylate
|
1,224.62 | 14.99 | 11,000 | 47,507 |
alanine-glyoxylate transaminase activity
|
1,142.49 | 14.33 | 10,998 | 50,913 |
transaminase activity
|
160.99 | 3.04 | 36,771 | 1,208,015 |
peroxisome
|
153.01 | 2.71 | 10,998 | 380,161 |
pyridoxal phosphate binding
|
86.42 | 1.63 | 28,238 | 1,728,166 |
Totals | 266116 | 48685386 |
No co-occurrence statistics for GO:0004648 based on MANUAL annotations
The top 20 of 20 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
|
9,712.77 | 100.00 | 133 | 133 |
L-serine biosynthetic process
|
4,176.18 | 42.86 | 132 | 307 |
pyridoxal phosphate binding
|
570.57 | 5.87 | 130 | 2,213 |
serine family amino acid biosynthetic process
|
2,158.39 | 1.43 | 2 | 9 |
L-serine metabolic process
|
396.44 | 1.11 | 2 | 49 |
lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate
|
4,856.39 | 0.75 | 1 | 2 |
purine nucleobase biosynthetic process
|
462.51 | 0.65 | 1 | 21 |
pyridoxine biosynthetic process
|
53.96 | 0.32 | 1 | 180 |
pyridoxal phosphate biosynthetic process
|
31.43 | 0.23 | 1 | 309 |
cytoplasm
|
6.98 | 0.07 | 129 | 179,389 |
Totals | 554 | 407624 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | phosphohydroxypyruvate transaminase activity |
2020-10-08 | Deleted | SYNONYM | 3PHP transaminase activity |
2020-10-08 | Deleted | SYNONYM | phosphohydroxypyruvate transaminase activity |
2020-10-08 | Deleted | SYNONYM | hydroxypyruvic phosphate--glutamic transaminase activity |
2020-10-08 | Deleted | SYNONYM | PSAT activity |
2020-10-08 | Deleted | SYNONYM | L-phosphoserine aminotransferase activity |
2020-10-08 | Deleted | SYNONYM | phosphohydroxypyruvic--glutamic transaminase activity |
2020-10-08 | Deleted | SYNONYM | 3-phosphoserine aminotransferase activity |
2020-10-08 | Added | SYNONYM | PSAT activity |
2020-10-08 | Added | SYNONYM | 3PHP transaminase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-03-29 | Updated | TERM | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
2003-03-19 | Updated | TERM | phosphoserine transaminase activity |
2002-02-06 | Updated | TERM | phosphoserine transaminase |
2001-04-03 | Updated | TERM | phosphoserine transaminase |
2001-03-30 | Added | TERM | phosphoserine transaminase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | phosphohydroxypyruvate transaminase activity |
2020-10-08 | Deleted | SYNONYM | 3PHP transaminase activity |
2020-10-08 | Deleted | SYNONYM | phosphohydroxypyruvate transaminase activity |
2020-10-08 | Deleted | SYNONYM | hydroxypyruvic phosphate--glutamic transaminase activity |
2020-10-08 | Deleted | SYNONYM | PSAT activity |
2020-10-08 | Deleted | SYNONYM | L-phosphoserine aminotransferase activity |
2020-10-08 | Deleted | SYNONYM | phosphohydroxypyruvic--glutamic transaminase activity |
2020-10-08 | Deleted | SYNONYM | 3-phosphoserine aminotransferase activity |
2020-10-08 | Added | SYNONYM | PSAT activity |
2020-10-08 | Added | SYNONYM | 3PHP transaminase activity |
2020-10-08 | Added | SYNONYM | phosphohydroxypyruvic--glutamic transaminase activity |
2020-10-08 | Added | SYNONYM | L-phosphoserine aminotransferase activity |
2020-10-08 | Added | SYNONYM | hydroxypyruvic phosphate--glutamic transaminase activity |
2020-10-08 | Added | SYNONYM | 3-phosphoserine aminotransferase activity |
2020-10-08 | Added | SYNONYM | 3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
2020-10-08 | Deleted | SYNONYM | 3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
2009-03-29 | Added | SYNONYM | phosphoserine transaminase activity |
2009-03-29 | Added | SYNONYM | phosphoserine aminotransferase activity |
2009-03-29 | Deleted | SYNONYM | phosphoserine aminotransferase activity |
2009-03-29 | Deleted | SYNONYM | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate. |
2007-11-08 | Added | SYNONYM | PdxC |
2007-11-08 | Added | SYNONYM | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
2007-11-08 | Added | SYNONYM | 3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
2007-11-08 | Added | SYNONYM | SerC |
2007-09-06 | Added | SYNONYM | phosphohydroxypyruvate transaminase activity |
2007-09-06 | Added | SYNONYM | hydroxypyruvic phosphate--glutamic transaminase activity |
2007-09-06 | Added | SYNONYM | PSAT activity |
2007-09-06 | Added | SYNONYM | 3PHP transaminase activity |
2007-09-06 | Added | SYNONYM | 3-phosphoserine aminotransferase activity |
2007-09-06 | Added | SYNONYM | phosphohydroxypyruvic--glutamic transaminase activity |
2007-09-06 | Added | SYNONYM | L-phosphoserine aminotransferase activity |
2007-08-09 | Deleted | SYNONYM | phosphoserine aminotransferase activity |
2007-08-09 | Added | SYNONYM | phosphoserine aminotransferase activity |
2004-04-19 | Added | SYNONYM | phosphoserine aminotransferase activity |
2004-04-16 | Deleted | SYNONYM | phosphoserine aminotransferase activity |
2003-10-27 | Added | SYNONYM | phosphoserine aminotransferase activity |
2003-08-21 | Deleted | SYNONYM | phosphoserine aminotransferase activity |
2003-06-10 | Added | SYNONYM | phosphoserine aminotransferase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0008483 (transaminase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Added | XREF | Reactome:R-HSA-977333 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-977333 |
2018-12-11 | Added | XREF | reactome:R-HSA-977333 |
2018-07-13 | Deleted | XREF | RHEA:14332 |
2018-07-13 | Added | XREF | RHEA:14329 |
2012-09-14 | Added | XREF | RHEA:14332 |
2003-10-27 | Added | XREF | MetaCyc:PSERTRANSAM-RXN |
2001-03-30 | Added | XREF | EC:2.6.1.52 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Added | SECONDARY | GO:0004646 (phosphoserine aminotransferase activity) |
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