GO:0004650
JSON
polygalacturonase activity
Molecular Function
Definition (GO:0004650 GONUTS page)
Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
endo-polygalacturonase activity | exact |
pectolase activity | related |
endopolygalacturonase activity | exact |
poly(1,4-alpha-D-galacturonide) glycanohydrolase activity | exact |
pectinase activity | narrow |
pectin depolymerase activity | narrow |
pectin hydrolase activity | related |
endo-D-galacturonase activity | exact |
endogalacturonase activity | exact |
pectin polygalacturonase activity | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004650
Child Term | Relationship to GO:0004650 |
---|---|
polygalacturonase inhibitor activity
|
negatively_regulates |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | E9PTA2 | 10116 | TRPM2_RAT | GO:0016787 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | O94759 | 9606 | TRPM2_HUMAN | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q62226 | 10090 | SHH_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113 | |
NOT-qualified manual | protein | Q63673 | 10116 | SHH_RAT | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q91YD4 | 10090 | TRPM2_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q93Y07 | 3702 | SFR2_ARATH | GO:0016798 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25100720 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 3.2.1.15 | |
InterPro | IPR000743 | Glycoside hydrolase, family 28 |
InterPro | IPR039279 | Polygalacturonase QRT3-like |
MetaCyc | RXN-2103 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004650 based on ALL annotations
The top 100 of 702 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
polygalacturonase activity
|
3,446.52 | 100.00 | 56,561 | 56,561 |
pectin catabolic process
|
353.27 | 6.11 | 7,435 | 72,537 |
rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity
|
3,446.52 | 2.97 | 1,680 | 1,680 |
hydrolase activity, acting on glycosyl bonds
|
96.03 | 2.78 | 51,141 | 1,835,510 |
alpha-galactosidase activity
|
187.48 | 2.62 | 2,725 | 50,095 |
hydrolase activity, hydrolyzing O-glycosyl compounds
|
78.88 | 2.23 | 26,566 | 1,160,741 |
cell wall organization
|
71.75 | 2.04 | 29,490 | 1,416,592 |
carbohydrate metabolic process
|
56.00 | 1.62 | 50,978 | 3,137,227 |
extracellular region
|
41.76 | 1.20 | 31,352 | 2,587,694 |
exo-poly-alpha-galacturonosidase activity
|
3,148.01 | 0.61 | 348 | 381 |
Totals | 286258 | 91074690 |
No co-occurrence statistics for GO:0004650 based on MANUAL annotations
The top 31 of 31 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
polygalacturonase activity
|
6,982.70 | 100.00 | 185 | 185 |
pectin catabolic process
|
575.12 | 7.60 | 92 | 1,117 |
galacturan 1,4-alpha-galacturonidase activity
|
6,109.86 | 3.76 | 7 | 8 |
cell wall modification involved in abscission
|
6,982.70 | 1.62 | 3 | 3 |
acquisition of nutrients from host
|
1,611.39 | 1.54 | 3 | 13 |
pectate lyase activity
|
537.13 | 0.96 | 2 | 26 |
fruit dehiscence
|
138.73 | 0.90 | 3 | 151 |
extracellular region
|
62.02 | 0.88 | 88 | 9,908 |
anther dehiscence
|
130.93 | 0.88 | 3 | 160 |
periplasmic space
|
117.03 | 0.83 | 3 | 179 |
Totals | 413 | 228840 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | pectolase activity |
2020-10-08 | Deleted | SYNONYM | pectin polygalacturonase activity |
2020-10-08 | Deleted | SYNONYM | pectin hydrolase activity |
2020-10-08 | Added | SYNONYM | pectin polygalacturonase activity |
2020-10-08 | Added | SYNONYM | pectolase activity |
2020-10-08 | Added | SYNONYM | pectin hydrolase activity |
2011-10-28 | Added | DEFINITION | Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans. |
2011-10-28 | Deleted | DEFINITION | Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans. |
2009-05-21 | Deleted | XREF | MetaCyc:3.2.1.15-RXN |
2009-05-21 | Added | XREF | MetaCyc:RXN-2103 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | polygalacturonase activity |
2002-02-06 | Updated | TERM | polygalacturonase |
2001-04-03 | Updated | TERM | polygalacturonase |
2001-03-30 | Added | TERM | polygalacturonase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | pectolase activity |
2020-10-08 | Deleted | SYNONYM | pectin polygalacturonase activity |
2020-10-08 | Deleted | SYNONYM | pectin hydrolase activity |
2020-10-08 | Added | SYNONYM | pectin polygalacturonase activity |
2020-10-08 | Added | SYNONYM | pectolase activity |
2020-10-08 | Added | SYNONYM | pectin hydrolase activity |
2011-10-28 | Added | DEFINITION | Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans. |
2011-10-28 | Deleted | DEFINITION | Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans. |
2008-05-13 | Added | DEFINITION | Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans. |
2007-11-08 | Added | SYNONYM | pectin hydrolase activity |
2007-11-08 | Added | SYNONYM | pectin polygalacturonase activity |
2007-11-08 | Added | SYNONYM | pectolase activity |
2007-09-06 | Added | SYNONYM | pectin depolymerase activity |
2007-09-06 | Added | SYNONYM | pectinase activity |
2007-08-09 | Added | SYNONYM | endogalacturonase activity |
2007-08-09 | Added | SYNONYM | endo-polygalacturonase activity |
2007-08-09 | Added | SYNONYM | endo-D-galacturonase activity |
2007-08-09 | Added | SYNONYM | endopolygalacturonase activity |
2007-08-09 | Deleted | SYNONYM | poly-alpha-1,4-galacturonide glycanohydrolase activity |
2007-08-09 | Deleted | SYNONYM | poly(1,4-alpha-D-galacturonide) glycanohydrolase activity |
2007-08-09 | Deleted | SYNONYM | endopolygalacturonase activity |
2007-08-09 | Deleted | SYNONYM | endogalacturonase activity |
2007-08-09 | Deleted | SYNONYM | endo-polygalacturonase activity |
2007-08-09 | Deleted | SYNONYM | endo-D-galacturonase activity |
2007-08-09 | Added | SYNONYM | poly-alpha-1,4-galacturonide glycanohydrolase activity |
2007-08-09 | Added | SYNONYM | poly(1,4-alpha-D-galacturonide) glycanohydrolase activity |
2005-09-18 | Added | SYNONYM | endopolygalacturonase activity |
2005-09-18 | Added | SYNONYM | endo-polygalacturonase activity |
2005-09-18 | Added | SYNONYM | endogalacturonase activity |
2005-09-18 | Added | SYNONYM | poly-alpha-1,4-galacturonide glycanohydrolase activity |
2005-09-18 | Added | SYNONYM | endo-D-galacturonase activity |
2005-09-18 | Added | SYNONYM | poly(1,4-alpha-D-galacturonide) glycanohydrolase activity |
2003-08-06 | Updated | DEFINITION | Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans. |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-05-21 | Deleted | XREF | MetaCyc:3.2.1.15-RXN |
2009-05-21 | Added | XREF | MetaCyc:RXN-2103 |
2003-10-27 | Added | XREF | MetaCyc:3.2.1.15-RXN |
2001-03-30 | Added | XREF | EC:3.2.1.15 |
Timestamp | Action | Category | Detail |
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