This term is obsolete.

GO:0004650 JSON

polygalacturonase activity

Molecular Function

Definition (GO:0004650 GONUTS page)

Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.

56,760 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
endo-polygalacturonase activity exact
pectolase activity related
endopolygalacturonase activity exact
poly(1,4-alpha-D-galacturonide) glycanohydrolase activity exact
pectinase activity narrow
pectin depolymerase activity narrow
pectin hydrolase activity related
endo-D-galacturonase activity exact
endogalacturonase activity exact
pectin polygalacturonase activity related

Ancestor Chart

Ancestor chart for GO:0004650
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004650

Child Term Relationship to
GO:0004650
polygalacturonase inhibitor activity
negatively_regulates

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q93Y07 3702 SFR2_ARATH GO:0016798 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25100720

Cross-references

Database ID Description
EC 3.2.1.15
InterPro IPR000743 Glycoside hydrolase, family 28
InterPro IPR039279 Polygalacturonase QRT3-like
MetaCyc RXN-2103

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004650 based on ALL annotations
The top 100 of 702 co-occurring terms
Co-occurring Term PR S% #Together #Compared
polygalacturonase activity
3,446.52 100.00 56,561 56,561
pectin catabolic process
353.27 6.11 7,435 72,537
rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity
3,446.52 2.97 1,680 1,680
hydrolase activity, acting on glycosyl bonds
96.03 2.78 51,141 1,835,510
alpha-galactosidase activity
187.48 2.62 2,725 50,095
hydrolase activity, hydrolyzing O-glycosyl compounds
78.88 2.23 26,566 1,160,741
cell wall organization
71.75 2.04 29,490 1,416,592
carbohydrate metabolic process
56.00 1.62 50,978 3,137,227
extracellular region
41.76 1.20 31,352 2,587,694
exo-poly-alpha-galacturonosidase activity
3,148.01 0.61 348 381
Totals 286258 91074690
No co-occurrence statistics for GO:0004650 based on MANUAL annotations
The top 31 of 31 co-occurring terms
Co-occurring Term PR S% #Together #Compared
polygalacturonase activity
6,982.70 100.00 185 185
pectin catabolic process
575.12 7.60 92 1,117
galacturan 1,4-alpha-galacturonidase activity
6,109.86 3.76 7 8
cell wall modification involved in abscission
6,982.70 1.62 3 3
acquisition of nutrients from host
1,611.39 1.54 3 13
pectate lyase activity
537.13 0.96 2 26
fruit dehiscence
138.73 0.90 3 151
extracellular region
62.02 0.88 88 9,908
anther dehiscence
130.93 0.88 3 160
periplasmic space
117.03 0.83 3 179
Totals 413 228840

Change Log

Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM pectolase activity
2020-10-08 Deleted SYNONYM pectin polygalacturonase activity
2020-10-08 Deleted SYNONYM pectin hydrolase activity
2020-10-08 Added SYNONYM pectin polygalacturonase activity
2020-10-08 Added SYNONYM pectolase activity
2020-10-08 Added SYNONYM pectin hydrolase activity
2011-10-28 Added DEFINITION Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2011-10-28 Deleted DEFINITION Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2009-05-21 Deleted XREF MetaCyc:3.2.1.15-RXN
2009-05-21 Added XREF MetaCyc:RXN-2103
Timestamp Action Category Detail
2003-03-19 Updated TERM polygalacturonase activity
2002-02-06 Updated TERM polygalacturonase
2001-04-03 Updated TERM polygalacturonase
2001-03-30 Added TERM polygalacturonase
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM pectolase activity
2020-10-08 Deleted SYNONYM pectin polygalacturonase activity
2020-10-08 Deleted SYNONYM pectin hydrolase activity
2020-10-08 Added SYNONYM pectin polygalacturonase activity
2020-10-08 Added SYNONYM pectolase activity
2020-10-08 Added SYNONYM pectin hydrolase activity
2011-10-28 Added DEFINITION Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2011-10-28 Deleted DEFINITION Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2008-05-13 Added DEFINITION Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2008-05-12 Deleted DEFINITION Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2007-11-08 Added SYNONYM pectin hydrolase activity
2007-11-08 Added SYNONYM pectin polygalacturonase activity
2007-11-08 Added SYNONYM pectolase activity
2007-09-06 Added SYNONYM pectin depolymerase activity
2007-09-06 Added SYNONYM pectinase activity
2007-08-09 Added SYNONYM endogalacturonase activity
2007-08-09 Added SYNONYM endo-polygalacturonase activity
2007-08-09 Added SYNONYM endo-D-galacturonase activity
2007-08-09 Added SYNONYM endopolygalacturonase activity
2007-08-09 Deleted SYNONYM poly-alpha-1,4-galacturonide glycanohydrolase activity
2007-08-09 Deleted SYNONYM poly(1,4-alpha-D-galacturonide) glycanohydrolase activity
2007-08-09 Deleted SYNONYM endopolygalacturonase activity
2007-08-09 Deleted SYNONYM endogalacturonase activity
2007-08-09 Deleted SYNONYM endo-polygalacturonase activity
2007-08-09 Deleted SYNONYM endo-D-galacturonase activity
2007-08-09 Added SYNONYM poly-alpha-1,4-galacturonide glycanohydrolase activity
2007-08-09 Added SYNONYM poly(1,4-alpha-D-galacturonide) glycanohydrolase activity
2005-09-18 Added SYNONYM endopolygalacturonase activity
2005-09-18 Added SYNONYM endo-polygalacturonase activity
2005-09-18 Added SYNONYM endogalacturonase activity
2005-09-18 Added SYNONYM poly-alpha-1,4-galacturonide glycanohydrolase activity
2005-09-18 Added SYNONYM endo-D-galacturonase activity
2005-09-18 Added SYNONYM poly(1,4-alpha-D-galacturonide) glycanohydrolase activity
2003-08-06 Updated DEFINITION Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2002-11-27 Added DEFINITION Catalysis of the reaction: random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:3.2.1.15-RXN
2009-05-21 Added XREF MetaCyc:RXN-2103
2003-10-27 Added XREF MetaCyc:3.2.1.15-RXN
2001-03-30 Added XREF EC:3.2.1.15
Timestamp Action Category Detail
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