GO:0004673
JSON
protein histidine kinase activity
Molecular Function
Definition (GO:0004673 GONUTS page)
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
Secondary IDs
GO:0008896
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
histidine protein kinase activity | related |
protein kinase (histidine) | related |
ATP:protein-L-histidine N-phosphotransferase activity | related |
protein-histidine kinase activity | exact |
histidine kinase activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004673
Child Term | Relationship to GO:0004673 |
---|---|
phosphorelay sensor kinase activity
|
is_a |
protein histidine kinase complex
|
capable_of |
regulation of protein histidine kinase activity
|
regulates |
transmembrane receptor histidine kinase activity
|
is_a |
protein histidine tele-kinase activity
|
is_a |
protein histidine pros-kinase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A0B4K7S5 | 7227 | A0A0B4K7S5_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:19809514 | |
NOT-qualified manual | protein | A0A0G2QC55 | 10116 | A0A0G2QC55_RAT | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A126GUQ5 | 7227 | A0A126GUQ5_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:19809514 | |
NOT-qualified manual | protein | A0A1L8END5 | 8355 | A0A1L8END5_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8EV37 | 8355 | A0A1L8EV37_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A4D6K026 | 7227 | A0A4D6K026_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A0A6M3Q8Y2 | 7227 | A0A6M3Q8Y2_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A0A8I3Q0M1 | 9615 | A0A8I3Q0M1_CANLF | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I5ZTU0 | 10116 | A0A8I5ZTU0_RAT | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.13.3 | |
InterPro | IPR003852 | Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal |
InterPro | IPR004105 | Histidine kinase CheA-like, homodimeric domain |
InterPro | IPR006290 | Heavy metal sensor kinase |
InterPro | IPR008358 | Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB |
InterPro | IPR010808 | Chemotaxis protein CheA, P2 response regulator-binding |
InterPro | IPR011102 | Signal transduction histidine kinase, HWE region |
InterPro | IPR011620 | Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region |
InterPro | IPR014302 | Signal transduction histidine kinase, TMAO sensor TorS |
InterPro | IPR014310 | Signal transduction histidine kinase, phosphate regulon sensor PhoR |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004673 based on ALL annotations
The top 100 of 414 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein histidine kinase activity
|
5,310.53 | 100.00 | 36,708 | 36,708 |
cellular hyperosmotic response
|
2,179.48 | 8.88 | 3,738 | 9,108 |
cytokinin-activated signaling pathway
|
863.26 | 7.80 | 4,791 | 29,473 |
photoreceptor activity
|
508.93 | 6.89 | 7,221 | 75,349 |
detection of visible light
|
309.92 | 2.26 | 1,307 | 22,396 |
phosphorelay sensor kinase activity
|
73.65 | 1.37 | 20,432 | 1,473,219 |
protein-glutamate methylesterase activity
|
113.31 | 1.19 | 968 | 45,367 |
circadian rhythm
|
139.65 | 1.03 | 608 | 23,121 |
cellular response to phosphate starvation
|
72.38 | 1.01 | 1,382 | 101,403 |
nitrogen fixation
|
62.66 | 0.86 | 1,143 | 96,875 |
Totals | 214838 | 160873517 |
No co-occurrence statistics for GO:0004673 based on MANUAL annotations
The top 100 of 163 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein histidine kinase activity
|
25,329.39 | 100.00 | 51 | 51 |
transmembrane histidine kinase cytokinin receptor activity
|
25,329.39 | 7.84 | 4 | 4 |
cellular hyperosmotic response
|
2,244.38 | 7.18 | 14 | 158 |
cytokinin receptor activity
|
25,329.39 | 5.88 | 3 | 3 |
secondary growth
|
18,997.04 | 5.77 | 3 | 4 |
regulation of meristem development
|
5,427.73 | 4.84 | 3 | 14 |
regulation of shoot system development
|
4,749.26 | 4.69 | 3 | 16 |
negative regulation of ethylene-activated signaling pathway
|
4,469.89 | 4.62 | 3 | 17 |
phosphotransferase activity, carboxyl group as acceptor
|
25,329.39 | 3.92 | 2 | 2 |
regulation of chlorophyll catabolic process
|
12,664.70 | 3.77 | 2 | 4 |
Totals | 261 | 11229 |
Change Log
- All changes
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-24 | Deleted | SYNONYM | histidine kinase (ambiguous) |
2022-07-24 | Deleted | SYNONYM | EnvZ |
2022-07-24 | Deleted | SYNONYM | histidine protein kinase (ambiguous) |
2022-07-24 | Deleted | SYNONYM | HP165 |
2022-07-24 | Deleted | SYNONYM | protein kinase (histidine) (ambiguous) |
2022-07-24 | Deleted | SYNONYM | Sln1p |
2022-07-24 | Deleted | SYNONYM | protein histidine kinase (ambiguous) |
2022-07-24 | Deleted | SYNONYM | HK1 |
2020-10-08 | Added | SYNONYM | protein kinase (histidine) |
2020-10-08 | Added | SYNONYM | protein histidine kinase (ambiguous) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-07-25 | Updated | TERM | protein histidine kinase activity |
2003-09-09 | Updated | TERM | protein-histidine kinase activity |
2003-03-19 | Updated | TERM | protein histidine kinase activity |
2002-02-06 | Updated | TERM | protein histidine kinase |
2001-04-03 | Updated | TERM | protein histidine kinase |
2001-03-30 | Added | TERM | protein histidine kinase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-24 | Deleted | SYNONYM | histidine kinase (ambiguous) |
2022-07-24 | Deleted | SYNONYM | EnvZ |
2022-07-24 | Deleted | SYNONYM | histidine protein kinase (ambiguous) |
2022-07-24 | Deleted | SYNONYM | HP165 |
2022-07-24 | Deleted | SYNONYM | protein kinase (histidine) (ambiguous) |
2022-07-24 | Deleted | SYNONYM | Sln1p |
2022-07-24 | Deleted | SYNONYM | protein histidine kinase (ambiguous) |
2022-07-24 | Deleted | SYNONYM | HK1 |
2020-10-08 | Added | SYNONYM | protein kinase (histidine) |
2020-10-08 | Added | SYNONYM | protein histidine kinase (ambiguous) |
2020-10-08 | Added | SYNONYM | histidine protein kinase (ambiguous) |
2020-10-08 | Added | SYNONYM | histidine kinase (ambiguous) |
2020-10-08 | Added | SYNONYM | ATP:protein-L-histidine N-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | protein kinase (histidine) (ambiguous) |
2020-10-08 | Added | SYNONYM | histidine protein kinase activity |
2020-10-08 | Deleted | SYNONYM | histidine protein kinase (ambiguous) |
2020-10-08 | Deleted | SYNONYM | histidine kinase (ambiguous) |
2020-10-08 | Deleted | SYNONYM | protein kinase (histidine) (ambiguous) |
2020-10-08 | Deleted | SYNONYM | protein histidine kinase (ambiguous) |
2020-10-08 | Deleted | SYNONYM | ATP:protein-L-histidine N-phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | protein kinase (histidine) |
2020-10-08 | Deleted | SYNONYM | histidine protein kinase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine. |
2007-11-08 | Added | SYNONYM | histidine protein kinase activity |
2007-11-08 | Added | SYNONYM | histidine kinase activity |
2007-11-08 | Added | SYNONYM | protein kinase (histidine) |
2007-11-08 | Added | SYNONYM | ATP:protein-L-histidine N-phosphotransferase activity |
2007-11-08 | Deleted | SYNONYM | histidine kinase |
2007-09-26 | Added | SYNONYM | EnvZ |
2007-09-26 | Added | SYNONYM | histidine kinase (ambiguous) |
2007-09-26 | Added | SYNONYM | Sln1p |
2007-09-26 | Added | SYNONYM | HP165 |
2007-09-26 | Added | SYNONYM | protein kinase (histidine) (ambiguous) |
2007-09-26 | Added | SYNONYM | histidine protein kinase (ambiguous) |
2007-09-26 | Added | SYNONYM | HK1 |
2007-09-26 | Added | SYNONYM | protein histidine kinase (ambiguous) |
2007-08-09 | Added | SYNONYM | histidine kinase |
2007-08-09 | Deleted | SYNONYM | protein-histidine kinase activity |
2007-08-09 | Deleted | SYNONYM | histidine kinase |
2007-08-09 | Added | SYNONYM | protein-histidine kinase activity |
2005-07-25 | Deleted | SYNONYM | protein histidine kinase activity |
2005-07-25 | Added | SYNONYM | protein-histidine kinase activity |
2004-09-23 | Added | SYNONYM | protein histidine kinase activity |
2004-09-11 | Added | DEFINITION | Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine. |
2004-04-19 | Added | SYNONYM | histidine kinase |
2004-04-16 | Deleted | SYNONYM | histidine kinase |
2003-02-28 | Added | SYNONYM | histidine kinase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-12-07 | Added | RELATION | has part GO:0038200 (ethylene receptor histidine kinase activity) |
2013-10-10 | Added | RELATION | part of GO:0018106 (peptidyl-histidine phosphorylation) |
2008-04-01 | Updated | RELATION | is a GO:0004672 (protein kinase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016775 (phosphotransferase activity, nitrogenous group as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-05-21 | Added | XREF | MetaCyc:2.7.13.3-RXN |
2007-09-26 | Added | XREF | EC:2.7.13.3 |
2007-09-26 | Deleted | XREF | EC:2.7.3.- |
2001-03-30 | Added | XREF | EC:2.7.3.- |
Timestamp | Action | Category | Detail |
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