This term is obsolete.

GO:0004837 JSON

tyrosine decarboxylase activity

Molecular Function

Definition (GO:0004837 GONUTS page)

Catalysis of the reaction: L-tyrosine = tyramine + CO2.

792 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
L-tyrosine carboxy-lyase activity related
L-tyrosine carboxy-lyase (tyramine-forming) related
L-(-)-tyrosine apodecarboxylase activity related
L-tyrosine decarboxylase activity related

Ancestor Chart

Ancestor chart for GO:0004837
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 4.1.1.25
MetaCyc TYROSINE-DECARBOXYLASE-RXN
RHEA 14345

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:327995 tyraminium
has_participant CHEBI CHEBI:58315 L-tyrosine zwitterion
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:16526 carbon dioxide

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004837 based on ALL annotations
The top 55 of 55 co-occurring terms
Co-occurring Term PR S% #Together #Compared
tyrosine decarboxylase activity
253,394.95 100.00 782 782
methanofuran biosynthetic process
124,129.31 35.22 435 888
aspartate 1-decarboxylase activity
5,747.62 2.24 529 23,322
tyramine biosynthetic process
221,720.61 0.89 7 8
L-dopa decarboxylase activity
15,714.42 0.89 8 129
aromatic-L-amino-acid decarboxylase activity
1,287.67 0.47 42 8,265
5-hydroxy-L-tryptophan decarboxylase activity
8,044.28 0.44 4 126
L-dopa metabolic process
190,046.23 0.38 3 4
diaminobutyrate decarboxylase activity
1,312.93 0.29 5 965
coenzyme A biosynthetic process
617.72 0.24 528 216,592
Totals 5136 160002550
No co-occurrence statistics for GO:0004837 based on MANUAL annotations
The top 21 of 21 co-occurring terms
Co-occurring Term PR S% #Together #Compared
tyrosine decarboxylase activity
128,321.19 100.00 11 11
L-dopa decarboxylase activity
64,160.59 26.67 4 8
L-dopa metabolic process
96,240.89 25.00 3 4
tyramine biosynthetic process
85,547.45 16.67 2 3
methanofuran biosynthetic process
128,321.19 9.09 1 1
aspartate 1-decarboxylase activity
3,564.48 2.17 1 36
aromatic-L-amino-acid decarboxylase activity
2,851.58 1.82 1 45
behavioral response to cocaine
2,251.25 1.49 1 57
behavioral response to ethanol
1,769.95 1.30 2 145
carboxy-lyase activity
1,268.00 0.98 5 506
Totals 48 213829

Change Log

Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM L-tyrosine carboxy-lyase activity
2020-10-08 Deleted SYNONYM L-tyrosine decarboxylase activity
2020-10-08 Deleted SYNONYM L-tyrosine carboxy-lyase (tyramine-forming)
2020-10-08 Deleted SYNONYM L-(-)-tyrosine apodecarboxylase activity
2020-10-08 Added SYNONYM L-(-)-tyrosine apodecarboxylase activity
2020-10-08 Added SYNONYM L-tyrosine decarboxylase activity
2020-10-08 Added SYNONYM L-tyrosine carboxy-lyase activity
2020-10-08 Added SYNONYM L-tyrosine carboxy-lyase (tyramine-forming)
2018-07-13 Added XREF RHEA:14345
2018-07-13 Deleted XREF RHEA:14348
Timestamp Action Category Detail
2003-03-19 Updated TERM tyrosine decarboxylase activity
2002-02-06 Updated TERM tyrosine decarboxylase
2001-04-03 Updated TERM tyrosine decarboxylase
2001-03-30 Added TERM tyrosine decarboxylase
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM L-tyrosine carboxy-lyase activity
2020-10-08 Deleted SYNONYM L-tyrosine decarboxylase activity
2020-10-08 Deleted SYNONYM L-tyrosine carboxy-lyase (tyramine-forming)
2020-10-08 Deleted SYNONYM L-(-)-tyrosine apodecarboxylase activity
2020-10-08 Added SYNONYM L-(-)-tyrosine apodecarboxylase activity
2020-10-08 Added SYNONYM L-tyrosine decarboxylase activity
2020-10-08 Added SYNONYM L-tyrosine carboxy-lyase activity
2020-10-08 Added SYNONYM L-tyrosine carboxy-lyase (tyramine-forming)
2008-05-13 Added DEFINITION Catalysis of the reaction: L-tyrosine = tyramine + CO2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-tyrosine = tyramine + CO2.
2007-11-08 Added SYNONYM L-(-)-tyrosine apodecarboxylase activity
2007-11-08 Added SYNONYM L-tyrosine decarboxylase activity
2007-11-08 Added SYNONYM L-tyrosine carboxy-lyase (tyramine-forming)
2007-09-06 Added SYNONYM L-tyrosine carboxy-lyase activity
2003-10-23 Updated DEFINITION Catalysis of the reaction: L-tyrosine = tyramine + CO2.
2002-11-27 Added DEFINITION Catalysis of the reaction: L-tyrosine = tyramine + carbon dioxide.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016831 (carboxy-lyase activity)
Timestamp Action Category Detail
2018-07-13 Added XREF RHEA:14345
2018-07-13 Deleted XREF RHEA:14348
2011-09-16 Added XREF RHEA:14348
2003-10-27 Added XREF MetaCyc:TYROSINE-DECARBOXYLASE-RXN
2001-03-30 Added XREF EC:4.1.1.25
Timestamp Action Category Detail
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