This term is obsolete.

GO:0004849 JSON

uridine kinase activity

Molecular Function

Definition (GO:0004849 GONUTS page)

Catalysis of the reaction: ATP + uridine = ADP + UMP.

18,762 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
uridine-cytidine kinase activity narrow
uridine phosphokinase activity exact

Ancestor Chart

Ancestor chart for GO:0004849
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Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I6AKN3 10116 A0A8I6AKN3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ALM9 10116 A0A8I6ALM9_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GLX5 10116 A0A8I6GLX5_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A1Z6G6 7227 A1Z6G6_DROME GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6IDC6 10116 A6IDC6_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L7 10116 A6K8L7_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L8 10116 A6K8L8_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZHG3 10116 D3ZHG3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZK09 10116 D3ZK09_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 2.7.1.48
InterPro IPR026008 Uridine kinase
MetaCyc URIDINEKIN-RXN
RHEA 16825
Reactome R-HSA-8954327

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:30616 ATP(4-)
has_participant CHEBI CHEBI:57865 uridine 5'-monophosphate(2-)
has_participant CHEBI CHEBI:16704 uridine
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:456216 ADP(3-)

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0006224 obsolete uridine kinase reaction replaced_by GO:0004849

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004849 based on ALL annotations
The top 100 of 262 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0004849
uridine kinase activity
10,727.31 100.00 18,472 18,472
GO:0044211
CTP salvage
9,608.53 75.33 15,253 17,029
GO:0009224
CMP biosynthetic process
10,614.16 46.99 8,724 8,817
GO:0043771
cytidine kinase activity
10,614.16 46.99 8,724 8,817
GO:0044206
UMP salvage
3,810.06 34.67 17,281 48,655
GO:0016773
phosphotransferase activity, alcohol group as acceptor
526.25 4.58 7,490 152,679
GO:0004845
uracil phosphoribosyltransferase activity
266.51 1.81 1,165 46,893
GO:0006222
UMP biosynthetic process
162.95 1.24 1,191 78,404
GO:0008655
pyrimidine-containing compound salvage
396.82 0.67 151 4,082
GO:0016301
kinase activity
37.00 0.34 18,451 5,349,025
Totals 131085 71154199
No co-occurrence statistics for GO:0004849 based on MANUAL annotations
The top 48 of 48 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0004849
uridine kinase activity
4,495.33 100.00 314 314
GO:0043771
cytidine kinase activity
3,995.85 7.57 24 27
GO:0044206
UMP salvage
3,322.63 5.31 17 23
GO:0044211
CTP salvage
4,495.33 4.78 15 15
GO:0008655
pyrimidine-containing compound salvage
1,926.57 4.49 15 35
GO:0004845
uracil phosphoribosyltransferase activity
128.44 0.72 3 105
GO:0009507
chloroplast
27.13 0.59 68 11,269
GO:2000904
regulation of starch metabolic process
76.19 0.47 2 118
GO:0046705
CDP biosynthetic process
34.98 0.35 2 257
GO:1901293
nucleoside phosphate biosynthetic process
1,123.83 0.32 1 4
Totals 827 715633

Change Log

Timestamp Action Category Detail
2023-03-14 Deleted SYNONYM ATP:uridine 5'-phosphotransferase activity
2023-03-14 Deleted SYNONYM uridine phosphokinase activity
2023-03-14 Deleted SYNONYM pyrimidine ribonucleoside kinase activity
2023-03-14 Deleted SYNONYM uridine kinase (phosphorylating)
2023-03-14 Deleted SYNONYM uridine kinase reaction
2023-03-14 Added SYNONYM uridine phosphokinase activity
2023-03-14 Deleted SYNONYM uridine-cytidine kinase activity
2023-03-14 Deleted SYNONYM uridine monophosphokinase activity
2023-03-14 Added SYNONYM uridine-cytidine kinase activity
2020-10-08 Added SYNONYM uridine phosphokinase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM uridine kinase activity
2002-02-06 Updated TERM uridine kinase
2001-04-03 Updated TERM uridine kinase
2001-03-30 Added TERM uridine kinase
Timestamp Action Category Detail
2023-03-14 Deleted SYNONYM ATP:uridine 5'-phosphotransferase activity
2023-03-14 Deleted SYNONYM uridine phosphokinase activity
2023-03-14 Deleted SYNONYM pyrimidine ribonucleoside kinase activity
2023-03-14 Deleted SYNONYM uridine kinase (phosphorylating)
2023-03-14 Deleted SYNONYM uridine kinase reaction
2023-03-14 Added SYNONYM uridine phosphokinase activity
2023-03-14 Deleted SYNONYM uridine-cytidine kinase activity
2023-03-14 Deleted SYNONYM uridine monophosphokinase activity
2023-03-14 Added SYNONYM uridine-cytidine kinase activity
2020-10-08 Added SYNONYM uridine phosphokinase activity
2020-10-08 Added SYNONYM ATP:uridine 5'-phosphotransferase activity
2020-10-08 Added SYNONYM pyrimidine ribonucleoside kinase activity
2020-10-08 Added SYNONYM uridine-cytidine kinase activity
2020-10-08 Deleted SYNONYM pyrimidine ribonucleoside kinase activity
2020-10-08 Deleted SYNONYM uridine kinase (phosphorylating)
2020-10-08 Deleted SYNONYM uridine phosphokinase activity
2020-10-08 Deleted SYNONYM uridine-cytidine kinase activity
2020-10-08 Deleted SYNONYM uridine monophosphokinase activity
2020-10-08 Added SYNONYM uridine kinase (phosphorylating)
2020-10-08 Added SYNONYM uridine monophosphokinase activity
2020-10-08 Deleted SYNONYM ATP:uridine 5'-phosphotransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + uridine = ADP + UMP.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + uridine = ADP + UMP.
2007-11-08 Added SYNONYM pyrimidine ribonucleoside kinase activity
2007-11-08 Added SYNONYM uridine kinase (phosphorylating)
2007-11-08 Added SYNONYM ATP:uridine 5'-phosphotransferase activity
2007-11-08 Added SYNONYM uridine-cytidine kinase activity
2007-11-08 Added SYNONYM uridine phosphokinase activity
2007-09-06 Added SYNONYM uridine monophosphokinase activity
2007-08-09 Deleted SYNONYM uridine kinase reaction
2007-08-09 Added SYNONYM uridine kinase reaction
2005-08-10 Added SYNONYM uridine kinase reaction
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + uridine = ADP + UMP.
Timestamp Action Category Detail
2011-03-11 Added RELATION part of GO:0006222 (UMP biosynthetic process)
2008-04-01 Updated RELATION is a GO:0019206 (nucleoside kinase activity)
Timestamp Action Category Detail
2019-04-01 Added XREF Reactome:R-HSA-8954327
2019-04-01 Deleted XREF reactome:R-HSA-8954327
2018-12-11 Added XREF reactome:R-HSA-8954327
2018-07-13 Deleted XREF RHEA:16828
2018-07-13 Added XREF RHEA:16825
2012-09-14 Added XREF RHEA:16828
2003-10-27 Added XREF MetaCyc:URIDINEKIN-RXN
2001-03-30 Added XREF EC:2.7.1.48
Timestamp Action Category Detail
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