GO:0004849
JSON
uridine kinase activity
Molecular Function
Definition (GO:0004849 GONUTS page)
Catalysis of the reaction: ATP + uridine = ADP + UMP.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
uridine-cytidine kinase activity | narrow |
uridine phosphokinase activity | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A8I6AKN3 | 10116 | A0A8I6AKN3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6ALM9 | 10116 | A0A8I6ALM9_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6GLX5 | 10116 | A0A8I6GLX5_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A1Z6G6 | 7227 | A1Z6G6_DROME | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6IDC6 | 10116 | A6IDC6_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K8L7 | 10116 | A6K8L7_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K8L8 | 10116 | A6K8L8_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZHG3 | 10116 | D3ZHG3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZK09 | 10116 | D3ZK09_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.1.48 | |
InterPro | IPR026008 | Uridine kinase |
MetaCyc | URIDINEKIN-RXN | |
RHEA | 16825 | |
Reactome | R-HSA-8954327 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:16704 | uridine |
has_participant | CHEBI | CHEBI:57865 | uridine 5'-monophosphate(2-) |
has_participant | CHEBI | CHEBI:456216 | ADP(3-) |
has_participant | CHEBI | CHEBI:30616 | ATP(4-) |
has_participant | CHEBI | CHEBI:15378 | hydron |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0006224 | obsolete uridine kinase reaction | replaced_by GO:0004849 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004849 based on ALL annotations
The top 100 of 260 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
uridine kinase activity
|
10,633.80 | 100.00 | 18,332 | 18,332 |
CTP salvage
|
9,482.50 | 74.98 | 15,122 | 16,958 |
CMP biosynthetic process
|
10,522.52 | 47.73 | 8,794 | 8,887 |
cytidine kinase activity
|
10,522.52 | 47.73 | 8,794 | 8,887 |
UMP salvage
|
3,781.33 | 34.71 | 17,155 | 48,243 |
phosphotransferase activity, alcohol group as acceptor
|
541.72 | 4.73 | 7,332 | 143,926 |
uracil phosphoribosyltransferase activity
|
268.49 | 1.84 | 1,165 | 46,141 |
UMP biosynthetic process
|
161.83 | 1.25 | 1,179 | 77,474 |
pyrimidine-containing compound salvage
|
399.98 | 0.68 | 152 | 4,041 |
kinase activity
|
37.31 | 0.35 | 18,315 | 5,220,332 |
Totals | 129484 | 70107110 |
No co-occurrence statistics for GO:0004849 based on MANUAL annotations
The top 51 of 51 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
uridine kinase activity
|
29,359.07 | 100.00 | 44 | 44 |
cytidine kinase activity
|
26,096.95 | 51.06 | 24 | 27 |
CTP salvage
|
29,359.07 | 34.09 | 15 | 15 |
UMP salvage
|
21,700.18 | 34.00 | 17 | 23 |
pyrimidine-containing compound salvage
|
12,582.46 | 23.44 | 15 | 35 |
nucleoside phosphate biosynthetic process
|
7,339.77 | 2.13 | 1 | 4 |
uracil phosphoribosyltransferase activity
|
855.12 | 2.08 | 3 | 103 |
regulation of cellulose biosynthetic process
|
4,893.18 | 2.04 | 1 | 6 |
pyrimidine nucleoside salvage
|
4,893.18 | 2.04 | 1 | 6 |
nucleoside monophosphate kinase activity
|
4,194.15 | 2.00 | 1 | 7 |
Totals | 223 | 672222 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-03-14 | Deleted | SYNONYM | uridine monophosphokinase activity |
2023-03-14 | Deleted | SYNONYM | uridine phosphokinase activity |
2023-03-14 | Deleted | SYNONYM | ATP:uridine 5'-phosphotransferase activity |
2023-03-14 | Deleted | SYNONYM | uridine kinase reaction |
2023-03-14 | Added | SYNONYM | uridine phosphokinase activity |
2023-03-14 | Deleted | SYNONYM | uridine kinase (phosphorylating) |
2023-03-14 | Deleted | SYNONYM | pyrimidine ribonucleoside kinase activity |
2023-03-14 | Deleted | SYNONYM | uridine-cytidine kinase activity |
2023-03-14 | Added | SYNONYM | uridine-cytidine kinase activity |
2020-10-08 | Added | SYNONYM | uridine kinase (phosphorylating) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | uridine kinase activity |
2002-02-06 | Updated | TERM | uridine kinase |
2001-04-03 | Updated | TERM | uridine kinase |
2001-03-30 | Added | TERM | uridine kinase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-03-14 | Deleted | SYNONYM | uridine monophosphokinase activity |
2023-03-14 | Deleted | SYNONYM | uridine phosphokinase activity |
2023-03-14 | Deleted | SYNONYM | ATP:uridine 5'-phosphotransferase activity |
2023-03-14 | Deleted | SYNONYM | uridine kinase reaction |
2023-03-14 | Added | SYNONYM | uridine phosphokinase activity |
2023-03-14 | Deleted | SYNONYM | uridine kinase (phosphorylating) |
2023-03-14 | Deleted | SYNONYM | pyrimidine ribonucleoside kinase activity |
2023-03-14 | Deleted | SYNONYM | uridine-cytidine kinase activity |
2023-03-14 | Added | SYNONYM | uridine-cytidine kinase activity |
2020-10-08 | Added | SYNONYM | uridine kinase (phosphorylating) |
2020-10-08 | Added | SYNONYM | uridine monophosphokinase activity |
2020-10-08 | Added | SYNONYM | uridine phosphokinase activity |
2020-10-08 | Deleted | SYNONYM | ATP:uridine 5'-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | ATP:uridine 5'-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | uridine-cytidine kinase activity |
2020-10-08 | Added | SYNONYM | pyrimidine ribonucleoside kinase activity |
2020-10-08 | Deleted | SYNONYM | uridine-cytidine kinase activity |
2020-10-08 | Deleted | SYNONYM | uridine phosphokinase activity |
2020-10-08 | Deleted | SYNONYM | uridine monophosphokinase activity |
2020-10-08 | Deleted | SYNONYM | pyrimidine ribonucleoside kinase activity |
2020-10-08 | Deleted | SYNONYM | uridine kinase (phosphorylating) |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + uridine = ADP + UMP. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + uridine = ADP + UMP. |
2007-11-08 | Added | SYNONYM | uridine phosphokinase activity |
2007-11-08 | Added | SYNONYM | uridine kinase (phosphorylating) |
2007-11-08 | Added | SYNONYM | pyrimidine ribonucleoside kinase activity |
2007-11-08 | Added | SYNONYM | uridine-cytidine kinase activity |
2007-11-08 | Added | SYNONYM | ATP:uridine 5'-phosphotransferase activity |
2007-09-06 | Added | SYNONYM | uridine monophosphokinase activity |
2007-08-09 | Added | SYNONYM | uridine kinase reaction |
2007-08-09 | Deleted | SYNONYM | uridine kinase reaction |
2005-08-10 | Added | SYNONYM | uridine kinase reaction |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: ATP + uridine = ADP + UMP. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-03-11 | Added | RELATION | part of GO:0006222 (UMP biosynthetic process) |
2008-04-01 | Updated | RELATION | is a GO:0019206 (nucleoside kinase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Deleted | XREF | reactome:R-HSA-8954327 |
2019-04-01 | Added | XREF | Reactome:R-HSA-8954327 |
2018-12-11 | Added | XREF | reactome:R-HSA-8954327 |
2018-07-13 | Added | XREF | RHEA:16825 |
2018-07-13 | Deleted | XREF | RHEA:16828 |
2012-09-14 | Added | XREF | RHEA:16828 |
2003-10-27 | Added | XREF | MetaCyc:URIDINEKIN-RXN |
2001-03-30 | Added | XREF | EC:2.7.1.48 |
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link