This term is obsolete.

GO:0004849 JSON

uridine kinase activity

Molecular Function

Definition (GO:0004849 GONUTS page)

Catalysis of the reaction: ATP + uridine = ADP + UMP.

18,381 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
uridine-cytidine kinase activity narrow
uridine phosphokinase activity exact

Ancestor Chart

Ancestor chart for GO:0004849
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I6AKN3 10116 A0A8I6AKN3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ALM9 10116 A0A8I6ALM9_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GLX5 10116 A0A8I6GLX5_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A1Z6G6 7227 A1Z6G6_DROME GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6IDC6 10116 A6IDC6_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L7 10116 A6K8L7_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L8 10116 A6K8L8_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZHG3 10116 D3ZHG3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZK09 10116 D3ZK09_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 2.7.1.48
InterPro IPR026008 Uridine kinase
MetaCyc URIDINEKIN-RXN
RHEA 16825
Reactome R-HSA-8954327

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:16704 uridine
has_participant CHEBI CHEBI:57865 uridine 5'-monophosphate(2-)
has_participant CHEBI CHEBI:456216 ADP(3-)
has_participant CHEBI CHEBI:30616 ATP(4-)
has_participant CHEBI CHEBI:15378 hydron

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0006224 obsolete uridine kinase reaction replaced_by GO:0004849

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004849 based on ALL annotations
The top 100 of 260 co-occurring terms
Co-occurring Term PR S% #Together #Compared
uridine kinase activity
10,633.80 100.00 18,332 18,332
CTP salvage
9,482.50 74.98 15,122 16,958
CMP biosynthetic process
10,522.52 47.73 8,794 8,887
cytidine kinase activity
10,522.52 47.73 8,794 8,887
UMP salvage
3,781.33 34.71 17,155 48,243
phosphotransferase activity, alcohol group as acceptor
541.72 4.73 7,332 143,926
uracil phosphoribosyltransferase activity
268.49 1.84 1,165 46,141
UMP biosynthetic process
161.83 1.25 1,179 77,474
pyrimidine-containing compound salvage
399.98 0.68 152 4,041
kinase activity
37.31 0.35 18,315 5,220,332
Totals 129484 70107110
No co-occurrence statistics for GO:0004849 based on MANUAL annotations
The top 51 of 51 co-occurring terms
Co-occurring Term PR S% #Together #Compared
uridine kinase activity
29,359.07 100.00 44 44
cytidine kinase activity
26,096.95 51.06 24 27
CTP salvage
29,359.07 34.09 15 15
UMP salvage
21,700.18 34.00 17 23
pyrimidine-containing compound salvage
12,582.46 23.44 15 35
nucleoside phosphate biosynthetic process
7,339.77 2.13 1 4
uracil phosphoribosyltransferase activity
855.12 2.08 3 103
regulation of cellulose biosynthetic process
4,893.18 2.04 1 6
pyrimidine nucleoside salvage
4,893.18 2.04 1 6
nucleoside monophosphate kinase activity
4,194.15 2.00 1 7
Totals 223 672222

Change Log

Timestamp Action Category Detail
2023-03-14 Deleted SYNONYM uridine monophosphokinase activity
2023-03-14 Deleted SYNONYM uridine phosphokinase activity
2023-03-14 Deleted SYNONYM ATP:uridine 5'-phosphotransferase activity
2023-03-14 Deleted SYNONYM uridine kinase reaction
2023-03-14 Added SYNONYM uridine phosphokinase activity
2023-03-14 Deleted SYNONYM uridine kinase (phosphorylating)
2023-03-14 Deleted SYNONYM pyrimidine ribonucleoside kinase activity
2023-03-14 Deleted SYNONYM uridine-cytidine kinase activity
2023-03-14 Added SYNONYM uridine-cytidine kinase activity
2020-10-08 Added SYNONYM uridine kinase (phosphorylating)
Timestamp Action Category Detail
2003-03-19 Updated TERM uridine kinase activity
2002-02-06 Updated TERM uridine kinase
2001-04-03 Updated TERM uridine kinase
2001-03-30 Added TERM uridine kinase
Timestamp Action Category Detail
2023-03-14 Deleted SYNONYM uridine monophosphokinase activity
2023-03-14 Deleted SYNONYM uridine phosphokinase activity
2023-03-14 Deleted SYNONYM ATP:uridine 5'-phosphotransferase activity
2023-03-14 Deleted SYNONYM uridine kinase reaction
2023-03-14 Added SYNONYM uridine phosphokinase activity
2023-03-14 Deleted SYNONYM uridine kinase (phosphorylating)
2023-03-14 Deleted SYNONYM pyrimidine ribonucleoside kinase activity
2023-03-14 Deleted SYNONYM uridine-cytidine kinase activity
2023-03-14 Added SYNONYM uridine-cytidine kinase activity
2020-10-08 Added SYNONYM uridine kinase (phosphorylating)
2020-10-08 Added SYNONYM uridine monophosphokinase activity
2020-10-08 Added SYNONYM uridine phosphokinase activity
2020-10-08 Deleted SYNONYM ATP:uridine 5'-phosphotransferase activity
2020-10-08 Added SYNONYM ATP:uridine 5'-phosphotransferase activity
2020-10-08 Added SYNONYM uridine-cytidine kinase activity
2020-10-08 Added SYNONYM pyrimidine ribonucleoside kinase activity
2020-10-08 Deleted SYNONYM uridine-cytidine kinase activity
2020-10-08 Deleted SYNONYM uridine phosphokinase activity
2020-10-08 Deleted SYNONYM uridine monophosphokinase activity
2020-10-08 Deleted SYNONYM pyrimidine ribonucleoside kinase activity
2020-10-08 Deleted SYNONYM uridine kinase (phosphorylating)
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + uridine = ADP + UMP.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + uridine = ADP + UMP.
2007-11-08 Added SYNONYM uridine phosphokinase activity
2007-11-08 Added SYNONYM uridine kinase (phosphorylating)
2007-11-08 Added SYNONYM pyrimidine ribonucleoside kinase activity
2007-11-08 Added SYNONYM uridine-cytidine kinase activity
2007-11-08 Added SYNONYM ATP:uridine 5'-phosphotransferase activity
2007-09-06 Added SYNONYM uridine monophosphokinase activity
2007-08-09 Added SYNONYM uridine kinase reaction
2007-08-09 Deleted SYNONYM uridine kinase reaction
2005-08-10 Added SYNONYM uridine kinase reaction
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + uridine = ADP + UMP.
Timestamp Action Category Detail
2011-03-11 Added RELATION part of GO:0006222 (UMP biosynthetic process)
2008-04-01 Updated RELATION is a GO:0019206 (nucleoside kinase activity)
Timestamp Action Category Detail
2019-04-01 Deleted XREF reactome:R-HSA-8954327
2019-04-01 Added XREF Reactome:R-HSA-8954327
2018-12-11 Added XREF reactome:R-HSA-8954327
2018-07-13 Added XREF RHEA:16825
2018-07-13 Deleted XREF RHEA:16828
2012-09-14 Added XREF RHEA:16828
2003-10-27 Added XREF MetaCyc:URIDINEKIN-RXN
2001-03-30 Added XREF EC:2.7.1.48
Timestamp Action Category Detail
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