This term is obsolete.

GO:0004896 JSON

cytokine receptor activity

Molecular Function

Definition (GO:0004896 GONUTS page)

Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

Secondary IDs

GO:0004907

105,782 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
IL receptor narrow
hematopoietin/interferon-class (D200-domain) cytokine receptor activity related
interleukin receptor activity narrow

Ancestor Chart

Ancestor chart for GO:0004896
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004896

Child Term Relationship to
GO:0004896
interleukin-21 receptor activity
is_a
glial cell-derived neurotrophic factor receptor activity
is_a
interleukin-24 receptor activity
is_a
chemokine receptor activity
is_a
interleukin-26 receptor activity
is_a
interleukin-1 receptor activity
is_a
interferon receptor activity
is_a
high mobility group box 1 receptor activity
is_a
granulocyte colony-stimulating factor receptor activity
is_a
prolactin receptor activity
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0004896 cytokine receptor activity Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Cross-references

Database ID Description
InterPro IPR003528 Long hematopoietin receptor, single chain, conserved site
InterPro IPR003529 Long hematopoietin receptor, Gp130 family 2, conserved site
InterPro IPR003530 Long hematopoietin receptor, soluble alpha chain, conserved site
InterPro IPR003531 Short hematopoietin receptor, family 1, conserved site
InterPro IPR003532 Short hematopoietin receptor, family 2, conserved site
InterPro IPR008355 Interferon gamma receptor alpha subunit
InterPro IPR011365 Cytokine IL-3/IL-5/GM-CSF receptor common beta chain
InterPro IPR015319 Interleukin-4 receptor alpha, N-terminal
InterPro IPR021126 Interferon gamma receptor, D2 domain, poxvirus/mammal

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004896 based on ALL annotations
The top 100 of 1,063 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cytokine receptor activity
4,884.58 100.00 39,909 39,909
cytokine-mediated signaling pathway
2,743.51 55.16 38,659 68,829
cytokine binding
1,990.52 9.17 4,221 10,358
external side of plasma membrane
484.33 9.12 21,176 213,567
immunoglobulin mediated immune response
3,050.04 7.73 3,237 5,184
macrophage migration inhibitory factor receptor complex
4,884.58 5.03 2,007 2,007
positive regulation of ERK1 and ERK2 cascade
405.85 4.00 2,862 34,445
interleukin-20 binding
4,812.75 3.69 1,474 1,496
hyaluronic acid binding
480.02 3.33 1,912 19,456
microvillus
275.77 2.56 1,783 31,581
Totals 170579 2608107
No co-occurrence statistics for GO:0004896 based on MANUAL annotations
The top 100 of 677 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cytokine receptor activity
1,891.36 100.00 683 683
cytokine binding
1,363.45 43.67 359 498
cytokine-mediated signaling pathway
775.68 38.81 600 1,463
receptor complex
220.65 10.40 334 2,863
external side of plasma membrane
156.16 7.99 484 5,862
positive regulation of cell population proliferation
167.58 7.95 297 3,352
immunoglobulin mediated immune response
193.75 5.92 84 820
ciliary neurotrophic factor receptor binding
1,015.73 4.10 29 54
interleukin-20 binding
1,595.84 3.92 27 32
macrophage migration inhibitory factor receptor complex
1,891.36 3.81 26 26
Totals 4038 40184

Change Log

Timestamp Action Category Detail
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2019-11-01 Added RELATION is a GO:0140375 (immune receptor activity)
2012-02-05 Deleted DEFINITION Combining with a cytokine to initiate a change in cell activity.
2012-02-05 Added DEFINITION Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2011-10-28 Deleted RELATION is a GO:0019955 (cytokine binding)
2010-06-15 Added RELATION part of GO:0019221 (cytokine-mediated signaling pathway)
2010-06-14 Deleted RELATION part of GO:0019221 (cytokine-mediated signaling pathway)
2010-06-08 Added RELATION part of GO:0019221 (cytokine-mediated signaling pathway)
2008-11-13 Added SYNONYM hematopoietin/interferon-class (D200-domain) cytokine receptor activity
2008-11-13 Added SYNONYM interleukin receptor activity
Timestamp Action Category Detail
2008-11-13 Updated TERM cytokine receptor activity
2003-03-19 Updated TERM hematopoietin/interferon-class (D200-domain) cytokine receptor activity
2002-07-09 Updated TERM hematopoietin/interferon-class (D200-domain) cytokine receptor
2002-02-06 Updated TERM hematopoeitin/interferon-class (D200-domain) cytokine receptor
2001-04-03 Updated TERM hematopoeitin/interferon-class (D200-domain) cytokine receptor
2001-03-30 Added TERM hematopoeitin/interferon-class (D200-domain) cytokine receptor
Timestamp Action Category Detail
2012-02-05 Deleted DEFINITION Combining with a cytokine to initiate a change in cell activity.
2012-02-05 Added DEFINITION Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2008-11-13 Added SYNONYM hematopoietin/interferon-class (D200-domain) cytokine receptor activity
2008-11-13 Added SYNONYM interleukin receptor activity
2008-11-13 Added DEFINITION Combining with a cytokine to initiate a change in cell activity.
2008-11-13 Added SYNONYM IL receptor
Timestamp Action Category Detail
2019-11-01 Added RELATION is a GO:0140375 (immune receptor activity)
2011-10-28 Deleted RELATION is a GO:0019955 (cytokine binding)
2010-06-15 Added RELATION part of GO:0019221 (cytokine-mediated signaling pathway)
2010-06-14 Deleted RELATION part of GO:0019221 (cytokine-mediated signaling pathway)
2010-06-08 Added RELATION part of GO:0019221 (cytokine-mediated signaling pathway)
2008-11-13 Added RELATION is a GO:0019955 (cytokine binding)
2008-04-01 Updated RELATION is a GO:0004888 (transmembrane signaling receptor activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2008-11-13 Added SECONDARY GO:0004907 (interleukin receptor activity)
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