GO:0004896
JSON
cytokine receptor activity
Molecular Function
Definition (GO:0004896 GONUTS page)
Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Secondary IDs
GO:0004907
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
IL receptor | narrow |
hematopoietin/interferon-class (D200-domain) cytokine receptor activity | related |
interleukin receptor activity | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004896
Child Term | Relationship to GO:0004896 |
---|---|
interleukin-21 receptor activity
|
is_a |
glial cell-derived neurotrophic factor receptor activity
|
is_a |
interleukin-24 receptor activity
|
is_a |
chemokine receptor activity
|
is_a |
interleukin-26 receptor activity
|
is_a |
interleukin-1 receptor activity
|
is_a |
interferon receptor activity
|
is_a |
high mobility group box 1 receptor activity
|
is_a |
granulocyte colony-stimulating factor receptor activity
|
is_a |
prolactin receptor activity
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0004896 | cytokine receptor activity | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR003528 | Long hematopoietin receptor, single chain, conserved site |
InterPro | IPR003529 | Long hematopoietin receptor, Gp130 family 2, conserved site |
InterPro | IPR003530 | Long hematopoietin receptor, soluble alpha chain, conserved site |
InterPro | IPR003531 | Short hematopoietin receptor, family 1, conserved site |
InterPro | IPR003532 | Short hematopoietin receptor, family 2, conserved site |
InterPro | IPR008355 | Interferon gamma receptor alpha subunit |
InterPro | IPR011365 | Cytokine IL-3/IL-5/GM-CSF receptor common beta chain |
InterPro | IPR015319 | Interleukin-4 receptor alpha, N-terminal |
InterPro | IPR021126 | Interferon gamma receptor, D2 domain, poxvirus/mammal |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004896 based on ALL annotations
The top 100 of 1,063 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cytokine receptor activity
|
4,884.58 | 100.00 | 39,909 | 39,909 |
cytokine-mediated signaling pathway
|
2,743.51 | 55.16 | 38,659 | 68,829 |
cytokine binding
|
1,990.52 | 9.17 | 4,221 | 10,358 |
external side of plasma membrane
|
484.33 | 9.12 | 21,176 | 213,567 |
immunoglobulin mediated immune response
|
3,050.04 | 7.73 | 3,237 | 5,184 |
macrophage migration inhibitory factor receptor complex
|
4,884.58 | 5.03 | 2,007 | 2,007 |
positive regulation of ERK1 and ERK2 cascade
|
405.85 | 4.00 | 2,862 | 34,445 |
interleukin-20 binding
|
4,812.75 | 3.69 | 1,474 | 1,496 |
hyaluronic acid binding
|
480.02 | 3.33 | 1,912 | 19,456 |
microvillus
|
275.77 | 2.56 | 1,783 | 31,581 |
Totals | 170579 | 2608107 |
No co-occurrence statistics for GO:0004896 based on MANUAL annotations
The top 100 of 677 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cytokine receptor activity
|
1,891.36 | 100.00 | 683 | 683 |
cytokine binding
|
1,363.45 | 43.67 | 359 | 498 |
cytokine-mediated signaling pathway
|
775.68 | 38.81 | 600 | 1,463 |
receptor complex
|
220.65 | 10.40 | 334 | 2,863 |
external side of plasma membrane
|
156.16 | 7.99 | 484 | 5,862 |
positive regulation of cell population proliferation
|
167.58 | 7.95 | 297 | 3,352 |
immunoglobulin mediated immune response
|
193.75 | 5.92 | 84 | 820 |
ciliary neurotrophic factor receptor binding
|
1,015.73 | 4.10 | 29 | 54 |
interleukin-20 binding
|
1,595.84 | 3.92 | 27 | 32 |
macrophage migration inhibitory factor receptor complex
|
1,891.36 | 3.81 | 26 | 26 |
Totals | 4038 | 40184 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-11-01 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2019-11-01 | Added | RELATION | is a GO:0140375 (immune receptor activity) |
2012-02-05 | Deleted | DEFINITION | Combining with a cytokine to initiate a change in cell activity. |
2012-02-05 | Added | DEFINITION | Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
2011-10-28 | Deleted | RELATION | is a GO:0019955 (cytokine binding) |
2010-06-15 | Added | RELATION | part of GO:0019221 (cytokine-mediated signaling pathway) |
2010-06-14 | Deleted | RELATION | part of GO:0019221 (cytokine-mediated signaling pathway) |
2010-06-08 | Added | RELATION | part of GO:0019221 (cytokine-mediated signaling pathway) |
2008-11-13 | Added | SYNONYM | hematopoietin/interferon-class (D200-domain) cytokine receptor activity |
2008-11-13 | Added | SYNONYM | interleukin receptor activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-11-13 | Updated | TERM | cytokine receptor activity |
2003-03-19 | Updated | TERM | hematopoietin/interferon-class (D200-domain) cytokine receptor activity |
2002-07-09 | Updated | TERM | hematopoietin/interferon-class (D200-domain) cytokine receptor |
2002-02-06 | Updated | TERM | hematopoeitin/interferon-class (D200-domain) cytokine receptor |
2001-04-03 | Updated | TERM | hematopoeitin/interferon-class (D200-domain) cytokine receptor |
2001-03-30 | Added | TERM | hematopoeitin/interferon-class (D200-domain) cytokine receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-02-05 | Deleted | DEFINITION | Combining with a cytokine to initiate a change in cell activity. |
2012-02-05 | Added | DEFINITION | Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
2008-11-13 | Added | SYNONYM | hematopoietin/interferon-class (D200-domain) cytokine receptor activity |
2008-11-13 | Added | SYNONYM | interleukin receptor activity |
2008-11-13 | Added | DEFINITION | Combining with a cytokine to initiate a change in cell activity. |
2008-11-13 | Added | SYNONYM | IL receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-11-01 | Added | RELATION | is a GO:0140375 (immune receptor activity) |
2011-10-28 | Deleted | RELATION | is a GO:0019955 (cytokine binding) |
2010-06-15 | Added | RELATION | part of GO:0019221 (cytokine-mediated signaling pathway) |
2010-06-14 | Deleted | RELATION | part of GO:0019221 (cytokine-mediated signaling pathway) |
2010-06-08 | Added | RELATION | part of GO:0019221 (cytokine-mediated signaling pathway) |
2008-11-13 | Added | RELATION | is a GO:0019955 (cytokine binding) |
2008-04-01 | Updated | RELATION | is a GO:0004888 (transmembrane signaling receptor activity) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-11-01 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2008-11-13 | Added | SECONDARY | GO:0004907 (interleukin receptor activity) |
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link