GO:0004908
JSON
interleukin-1 receptor activity
Molecular Function
Definition (GO:0004908 GONUTS page)
Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
IL-1R | exact |
IL-1 receptor activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004908
Child Term | Relationship to GO:0004908 |
---|---|
interleukin-1, type II, blocking receptor activity
|
is_a |
interleukin-1 receptor complex
|
capable_of |
interleukin-1, type I, activating receptor activity
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0004908 | interleukin-1 receptor activity | Never in Taxon | 2 | Bacteria | |
GO:0004908 | interleukin-1 receptor activity | Never in Taxon | 2157 | Archaea | |
GO:0004908 | interleukin-1 receptor activity | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR004074 | Interleukin-1 receptor type I/II |
Wikipedia | Interleukin-1_receptor |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004908 based on ALL annotations
The top 100 of 199 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
interleukin-1 receptor activity
|
49,792.79 | 100.00 | 3,915 | 3,915 |
interleukin-1 binding
|
40,182.27 | 24.43 | 1,016 | 1,259 |
interleukin-1, type II, blocking receptor activity
|
39,172.00 | 15.35 | 627 | 797 |
interleukin-18 receptor activity
|
16,547.11 | 9.12 | 437 | 1,315 |
interleukin-33 binding
|
28,065.03 | 8.85 | 372 | 660 |
interleukin-18-mediated signaling pathway
|
12,762.14 | 8.43 | 437 | 1,705 |
interleukin-1, type I, activating receptor activity
|
11,351.94 | 5.71 | 277 | 1,215 |
interleukin-1-mediated signaling pathway
|
5,729.88 | 5.48 | 371 | 3,224 |
cytokine-mediated signaling pathway
|
2,299.78 | 4.57 | 3,179 | 68,829 |
negative regulation of exocytosis
|
6,787.08 | 4.10 | 217 | 1,592 |
Totals | 20411 | 5102840 |
No co-occurrence statistics for GO:0004908 based on MANUAL annotations
The top 60 of 60 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
interleukin-1 receptor activity
|
33,994.71 | 100.00 | 38 | 38 |
interleukin-1 binding
|
8,945.98 | 9.62 | 5 | 19 |
interleukin-1-mediated signaling pathway
|
3,263.49 | 7.95 | 12 | 125 |
positive regulation of interleukin-1-mediated signaling pathway
|
33,994.71 | 5.26 | 2 | 2 |
interleukin-33 receptor activity
|
13,597.89 | 4.88 | 2 | 5 |
interleukin-33-mediated signaling pathway
|
3,187.00 | 4.48 | 3 | 32 |
negative regulation of interleukin-1 alpha production
|
5,665.79 | 4.17 | 2 | 12 |
trans-synaptic signaling by trans-synaptic complex
|
3,999.38 | 3.77 | 2 | 17 |
positive regulation of T-helper 1 cell cytokine production
|
1,671.87 | 3.13 | 3 | 61 |
negative regulation of interleukin-1-mediated signaling pathway
|
1,446.58 | 2.41 | 2 | 47 |
Totals | 264 | 522562 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-02 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2024-09-02 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-02 | Deleted | CONSTRAINT | never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea) |
2023-11-01 | Added | CONSTRAINT | never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea) |
2011-10-28 | Deleted | RELATION | is a GO:0019966 (interleukin-1 binding) |
2009-06-11 | Deleted | XREF | Wikipedia::Interleukin-1_receptor |
2009-06-11 | Added | XREF | Wikipedia:Interleukin-1_receptor |
2009-02-25 | Added | XREF | Wikipedia::Interleukin-1_receptor |
2008-12-08 | Added | SYNONYM | IL-1 receptor activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | interleukin-1 receptor activity |
2002-02-06 | Updated | TERM | interleukin-1 receptor |
2001-04-03 | Updated | TERM | interleukin-1 receptor |
2001-03-30 | Added | TERM | interleukin-1 receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-12-08 | Added | SYNONYM | IL-1 receptor activity |
2008-05-13 | Added | DEFINITION | Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response. |
2008-05-12 | Deleted | DEFINITION | Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response. |
2007-08-09 | Added | SYNONYM | IL-1R |
2007-08-09 | Deleted | SYNONYM | IL-1R |
2004-04-19 | Added | SYNONYM | IL-1R |
2004-04-16 | Deleted | SYNONYM | IL-1R |
2004-01-03 | Updated | DEFINITION | Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response. |
2003-05-08 | Updated | DEFINITION | The function of combining with interleukin-1 to initiate a change in cell function. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response. |
2002-11-27 | Added | DEFINITION | Combines with a high structural selectivity to interleukin-1, specifically altering cell function. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response. |
2002-08-24 | Added | SYNONYM | IL-1R |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-10-28 | Deleted | RELATION | is a GO:0019966 (interleukin-1 binding) |
2008-11-13 | Added | RELATION | is a GO:0004896 (cytokine receptor activity) |
2008-11-13 | Deleted | RELATION | is a GO:0004907 (interleukin receptor activity) |
2008-04-01 | Updated | RELATION | is a GO:0004907 (interleukin receptor activity) |
2008-04-01 | Updated | RELATION | is a GO:0019966 (interleukin-1 binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-06-11 | Deleted | XREF | Wikipedia::Interleukin-1_receptor |
2009-06-11 | Added | XREF | Wikipedia:Interleukin-1_receptor |
2009-02-25 | Added | XREF | Wikipedia::Interleukin-1_receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-02 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2024-09-02 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-02 | Deleted | CONSTRAINT | never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea) |
2023-11-01 | Added | CONSTRAINT | never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea) |
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