This term is obsolete.

GO:0004913 JSON

interleukin-4 receptor activity

Molecular Function

Definition (GO:0004913 GONUTS page)

Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

73 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
IL-4 receptor activity exact
IL-4R exact

Ancestor Chart

Ancestor chart for GO:0004913
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004913

Child Term Relationship to
GO:0004913
interleukin-4 receptor complex
capable_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0004913 interleukin-4 receptor activity Never in Taxon 2 Bacteria
GO:0004913 interleukin-4 receptor activity Never in Taxon 2157 Archaea
GO:0004913 interleukin-4 receptor activity Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004913 based on ALL annotations
The top 63 of 63 co-occurring terms
Co-occurring Term PR S% #Together #Compared
interleukin-4 receptor activity
2,752,151.00 100.00 72 72
negative regulation of T-helper 1 cell differentiation
982,911.10 27.78 40 112
positive regulation of T-helper 2 cell differentiation
326,664.80 10.84 40 337
interleukin-4-mediated signaling pathway
274,073.12 9.96 72 723
positive regulation of mast cell degranulation
240,362.55 8.16 40 458
production of molecular mediator involved in inflammatory response
164,271.98 5.95 69 1,156
T-helper 1 cell differentiation
148,966.23 5.19 40 739
T-helper 2 cell differentiation
142,230.02 4.96 40 774
positive regulation of myoblast fusion
102,120.63 3.60 40 1,078
positive regulation of leukocyte differentiation
1,834,767.20 2.74 2 3
Totals 1297 99057524
No co-occurrence statistics for GO:0004913 based on MANUAL annotations
The top 50 of 50 co-occurring terms
Co-occurring Term PR S% #Together #Compared
interleukin-4 receptor activity
282,306.60 100.00 5 5
positive regulation of leukocyte differentiation
188,204.40 33.33 2 3
interleukin-4-mediated signaling pathway
29,716.48 10.26 4 38
interleukin-7 receptor activity
47,051.10 10.00 1 6
negative regulation of T-helper 1 cell differentiation
28,230.66 7.14 1 10
interleukin-2 receptor activity
28,230.66 7.14 1 10
positive regulation of T-helper 2 cell differentiation
10,857.95 3.33 1 26
T-helper 2 cell differentiation
7,841.85 2.50 1 36
interleukin-7-mediated signaling pathway
6,721.59 2.17 1 42
interleukin-9-mediated signaling pathway
6,565.27 2.13 1 43
Totals 78 462439

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-02 Deleted CONSTRAINT never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea)
2024-09-02 Added CONSTRAINT never_in_taxon NCBITaxon:2 (Bacteria)
2024-09-02 Added CONSTRAINT never_in_taxon NCBITaxon:2157 (Archaea)
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea)
2012-02-09 Added DEFINITION Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2012-02-09 Deleted DEFINITION Combining with interleukin-4 to initiate a change in cell activity.
2011-10-28 Deleted RELATION is a GO:0019979 (interleukin-4 binding)
2011-04-03 Added RELATION part of GO:0035771 (interleukin-4-mediated signaling pathway)
2008-12-08 Added SYNONYM IL-4 receptor activity
Timestamp Action Category Detail
2003-03-19 Updated TERM interleukin-4 receptor activity
2002-02-06 Updated TERM interleukin-4 receptor
2001-04-03 Updated TERM interleukin-4 receptor
2001-03-30 Added TERM interleukin-4 receptor
Timestamp Action Category Detail
2012-02-09 Added DEFINITION Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2012-02-09 Deleted DEFINITION Combining with interleukin-4 to initiate a change in cell activity.
2008-12-08 Added SYNONYM IL-4 receptor activity
2008-05-13 Added DEFINITION Combining with interleukin-4 to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with interleukin-4 to initiate a change in cell activity.
2007-08-09 Added SYNONYM IL-4R
2007-08-09 Deleted SYNONYM IL-4R
2004-04-19 Added SYNONYM IL-4R
2004-04-16 Deleted SYNONYM IL-4R
2004-01-03 Updated DEFINITION Combining with interleukin-4 to initiate a change in cell activity.
2003-05-08 Updated DEFINITION The function of combining with interleukin-4 to initiate a change in cell function.
2002-11-27 Added DEFINITION Combines with a high structural selectivity to interleukin-4, specifically altering cell function.
2002-08-24 Added SYNONYM IL-4R
Timestamp Action Category Detail
2011-10-28 Deleted RELATION is a GO:0019979 (interleukin-4 binding)
2011-04-03 Added RELATION part of GO:0035771 (interleukin-4-mediated signaling pathway)
2008-11-13 Deleted RELATION is a GO:0004907 (interleukin receptor activity)
2008-11-13 Added RELATION is a GO:0004896 (cytokine receptor activity)
2008-04-01 Updated RELATION is a GO:0004907 (interleukin receptor activity)
2008-04-01 Updated RELATION is a GO:0019979 (interleukin-4 binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-02 Deleted CONSTRAINT never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea)
2024-09-02 Added CONSTRAINT never_in_taxon NCBITaxon:2 (Bacteria)
2024-09-02 Added CONSTRAINT never_in_taxon NCBITaxon:2157 (Archaea)
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea)
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