GO:0004913
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interleukin-4 receptor activity
Molecular Function
Definition (GO:0004913 GONUTS page)
Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
IL-4 receptor activity | exact |
IL-4R | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004913
Child Term | Relationship to GO:0004913 |
---|---|
interleukin-4 receptor complex
|
capable_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0004913 | interleukin-4 receptor activity | Never in Taxon | 2 | Bacteria | |
GO:0004913 | interleukin-4 receptor activity | Never in Taxon | 2157 | Archaea | |
GO:0004913 | interleukin-4 receptor activity | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004913 based on ALL annotations
The top 63 of 63 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
interleukin-4 receptor activity
|
2,752,151.00 | 100.00 | 72 | 72 |
negative regulation of T-helper 1 cell differentiation
|
982,911.10 | 27.78 | 40 | 112 |
positive regulation of T-helper 2 cell differentiation
|
326,664.80 | 10.84 | 40 | 337 |
interleukin-4-mediated signaling pathway
|
274,073.12 | 9.96 | 72 | 723 |
positive regulation of mast cell degranulation
|
240,362.55 | 8.16 | 40 | 458 |
production of molecular mediator involved in inflammatory response
|
164,271.98 | 5.95 | 69 | 1,156 |
T-helper 1 cell differentiation
|
148,966.23 | 5.19 | 40 | 739 |
T-helper 2 cell differentiation
|
142,230.02 | 4.96 | 40 | 774 |
positive regulation of myoblast fusion
|
102,120.63 | 3.60 | 40 | 1,078 |
positive regulation of leukocyte differentiation
|
1,834,767.20 | 2.74 | 2 | 3 |
Totals | 1297 | 99057524 |
No co-occurrence statistics for GO:0004913 based on MANUAL annotations
The top 50 of 50 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
interleukin-4 receptor activity
|
282,306.60 | 100.00 | 5 | 5 |
positive regulation of leukocyte differentiation
|
188,204.40 | 33.33 | 2 | 3 |
interleukin-4-mediated signaling pathway
|
29,716.48 | 10.26 | 4 | 38 |
interleukin-7 receptor activity
|
47,051.10 | 10.00 | 1 | 6 |
negative regulation of T-helper 1 cell differentiation
|
28,230.66 | 7.14 | 1 | 10 |
interleukin-2 receptor activity
|
28,230.66 | 7.14 | 1 | 10 |
positive regulation of T-helper 2 cell differentiation
|
10,857.95 | 3.33 | 1 | 26 |
T-helper 2 cell differentiation
|
7,841.85 | 2.50 | 1 | 36 |
interleukin-7-mediated signaling pathway
|
6,721.59 | 2.17 | 1 | 42 |
interleukin-9-mediated signaling pathway
|
6,565.27 | 2.13 | 1 | 43 |
Totals | 78 | 462439 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-02 | Deleted | CONSTRAINT | never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea) |
2024-09-02 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2024-09-02 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2023-11-01 | Added | CONSTRAINT | never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea) |
2012-02-09 | Added | DEFINITION | Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
2012-02-09 | Deleted | DEFINITION | Combining with interleukin-4 to initiate a change in cell activity. |
2011-10-28 | Deleted | RELATION | is a GO:0019979 (interleukin-4 binding) |
2011-04-03 | Added | RELATION | part of GO:0035771 (interleukin-4-mediated signaling pathway) |
2008-12-08 | Added | SYNONYM | IL-4 receptor activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | interleukin-4 receptor activity |
2002-02-06 | Updated | TERM | interleukin-4 receptor |
2001-04-03 | Updated | TERM | interleukin-4 receptor |
2001-03-30 | Added | TERM | interleukin-4 receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-02-09 | Added | DEFINITION | Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
2012-02-09 | Deleted | DEFINITION | Combining with interleukin-4 to initiate a change in cell activity. |
2008-12-08 | Added | SYNONYM | IL-4 receptor activity |
2008-05-13 | Added | DEFINITION | Combining with interleukin-4 to initiate a change in cell activity. |
2008-05-12 | Deleted | DEFINITION | Combining with interleukin-4 to initiate a change in cell activity. |
2007-08-09 | Added | SYNONYM | IL-4R |
2007-08-09 | Deleted | SYNONYM | IL-4R |
2004-04-19 | Added | SYNONYM | IL-4R |
2004-04-16 | Deleted | SYNONYM | IL-4R |
2004-01-03 | Updated | DEFINITION | Combining with interleukin-4 to initiate a change in cell activity. |
2003-05-08 | Updated | DEFINITION | The function of combining with interleukin-4 to initiate a change in cell function. |
2002-11-27 | Added | DEFINITION | Combines with a high structural selectivity to interleukin-4, specifically altering cell function. |
2002-08-24 | Added | SYNONYM | IL-4R |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-10-28 | Deleted | RELATION | is a GO:0019979 (interleukin-4 binding) |
2011-04-03 | Added | RELATION | part of GO:0035771 (interleukin-4-mediated signaling pathway) |
2008-11-13 | Deleted | RELATION | is a GO:0004907 (interleukin receptor activity) |
2008-11-13 | Added | RELATION | is a GO:0004896 (cytokine receptor activity) |
2008-04-01 | Updated | RELATION | is a GO:0004907 (interleukin receptor activity) |
2008-04-01 | Updated | RELATION | is a GO:0019979 (interleukin-4 binding) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-02 | Deleted | CONSTRAINT | never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea) |
2024-09-02 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2024-09-02 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2023-11-01 | Added | CONSTRAINT | never_in_taxon NCBITaxon_Union:23 (Fungi or Bacteria or Archaea) |
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