This term is obsolete.

GO:0004939 JSON

beta-adrenergic receptor activity

Molecular Function

Definition (GO:0004939 GONUTS page)

Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.

3,390 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
beta adrenoceptor exact

Ancestor Chart

Ancestor chart for GO:0004939
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004939

Child Term Relationship to
GO:0004939
beta2-adrenergic receptor activity
is_a
beta3-adrenergic receptor activity
is_a
beta1-adrenergic receptor activity
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0004939 beta-adrenergic receptor activity Only in Taxon 6072 Eumetazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A2ARI4 10090 LGR4_MOUSE GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:21693646
NOT-qualified manual protein B0BLW3 8364 LGR4_XENTR GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein D4AC13 10116 LGR5_RAT GO:0004930 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein E5DHB5 8355 LGR5A_XENLA GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein E7FE13 7955 LGR4_DANRE GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein F1MLX5 9913 LGR4_BOVIN GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein F1MT22 9913 LGR5_BOVIN GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein F7D3V9 8364 LGR5_XENTR GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein G3QNC0 9595 G3QNC0_GORGO GO:0007186 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:8910290
NOT-qualified manual protein O15529 9606 GPR42_HUMAN GO:0007186 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12496283

Cross-references

Database ID Description
InterPro IPR000681 Beta 3 adrenoceptor

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004939 based on ALL annotations
The top 60 of 60 co-occurring terms
Co-occurring Term PR S% #Together #Compared
beta-adrenergic receptor activity
789,225.80 100.00 247 247
beta3-adrenergic receptor activity
230,664.97 28.34 223 763
beta-3 adrenergic receptor binding
328,488.60 21.69 77 185
heat generation
176,388.58 15.06 78 349
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
67,874.03 8.52 223 2,593
diet induced thermogenesis
80,786.89 8.38 78 762
norepinephrine binding
52,723.77 6.05 97 1,452
negative regulation of multicellular organism growth
53,952.34 5.95 78 1,141
epinephrine binding
38,222.13 4.81 219 4,522
brown fat cell differentiation
22,586.72 2.67 69 2,411
Totals 3536 99546896
No co-occurrence statistics for GO:0004939 based on MANUAL annotations
The top 40 of 40 co-occurring terms
Co-occurring Term PR S% #Together #Compared
beta-adrenergic receptor activity
86,119.94 100.00 15 15
beta3-adrenergic receptor activity
41,575.14 46.67 14 29
norepinephrine binding
24,605.70 28.00 14 49
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
10,764.99 11.27 8 64
beta-3 adrenergic receptor binding
34,447.98 11.11 2 5
epinephrine binding
6,079.05 6.38 6 85
heat generation
6,379.25 5.00 2 27
diet induced thermogenesis
3,444.80 3.17 2 50
beta1-adrenergic receptor activity
3,588.33 2.63 1 24
adenylate cyclase-activating adrenergic receptor signaling pathway
2,215.78 2.57 15 583
Totals 168 269094

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
2010-06-09 Updated TERM beta-adrenergic receptor activity
2010-06-08 Updated TERM beta-adrenergic receptor activity
2009-03-02 Added DEFINITION Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.
2009-03-02 Deleted DEFINITION Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors.
2009-02-25 Added DEFINITION Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors.
2008-04-01 Updated RELATION is a GO:0004935 (adrenergic receptor activity)
2007-08-09 Deleted SYNONYM beta adrenoceptor
2007-08-09 Added SYNONYM beta adrenoceptor
2004-04-19 Added SYNONYM beta adrenoceptor
Timestamp Action Category Detail
2010-06-09 Updated TERM beta-adrenergic receptor activity
2010-06-08 Updated TERM beta-adrenergic receptor activity
2003-03-19 Updated TERM beta-adrenergic receptor activity
2002-02-06 Updated TERM beta-adrenergic receptor
2002-01-09 Updated TERM beta-adrenergic receptor
2001-04-03 Updated TERM beta adrenergic receptor
2001-03-30 Added TERM beta adrenergic receptor
Timestamp Action Category Detail
2009-03-02 Added DEFINITION Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.
2009-03-02 Deleted DEFINITION Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors.
2009-02-25 Added DEFINITION Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors.
2007-08-09 Deleted SYNONYM beta adrenoceptor
2007-08-09 Added SYNONYM beta adrenoceptor
2004-04-19 Added SYNONYM beta adrenoceptor
2004-04-16 Deleted SYNONYM beta adrenoceptor
2002-01-09 Added SYNONYM beta adrenoceptor
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004935 (adrenergic receptor activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.