GO:0004995
JSON
tachykinin receptor activity
Molecular Function
Definition (GO:0004995 GONUTS page)
Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein. PMID:7639617
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004995
Child Term | Relationship to GO:0004995 |
---|---|
substance K receptor activity
|
is_a |
neuromedin K receptor activity
|
is_a |
substance P receptor activity
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0004995 | tachykinin receptor activity | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A2ARI4 | 10090 | LGR4_MOUSE | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:21693646 | |
NOT-qualified manual | protein | B0BLW3 | 8364 | LGR4_XENTR | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | D4AC13 | 10116 | LGR5_RAT | GO:0004930 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | E5DHB5 | 8355 | LGR5A_XENLA | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | E7FE13 | 7955 | LGR4_DANRE | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F1MLX5 | 9913 | LGR4_BOVIN | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F1MT22 | 9913 | LGR5_BOVIN | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F7D3V9 | 8364 | LGR5_XENTR | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | G3QNC0 | 9595 | G3QNC0_GORGO | GO:0007186 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:8910290 | |
NOT-qualified manual | protein | O15529 | 9606 | GPR42_HUMAN | GO:0007186 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12496283 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000046 | Neurokinin NK1 receptor |
InterPro | IPR000913 | Neurokinin NK2 receptor |
InterPro | IPR001013 | Neurokinin NK3 receptor |
InterPro | IPR001681 | Neurokinin receptor |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004995 based on ALL annotations
The top 100 of 141 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
tachykinin receptor activity
|
40,494.14 | 100.00 | 4,814 | 4,814 |
tachykinin receptor signaling pathway
|
27,972.28 | 69.08 | 4,814 | 6,969 |
positive regulation of flagellated sperm motility
|
27,436.64 | 51.45 | 3,280 | 4,841 |
sperm midpiece
|
14,774.28 | 31.17 | 3,280 | 8,990 |
substance P receptor activity
|
40,494.14 | 21.92 | 1,055 | 1,055 |
substance K receptor activity
|
40,494.14 | 18.05 | 869 | 869 |
regulation of uterine smooth muscle contraction
|
25,910.58 | 3.72 | 183 | 286 |
sperm head
|
7,427.22 | 3.33 | 188 | 1,025 |
response to pain
|
2,272.82 | 1.03 | 60 | 1,069 |
cellular response to cocaine
|
2,917.96 | 0.90 | 49 | 680 |
Totals | 33980 | 25818507 |
No co-occurrence statistics for GO:0004995 based on MANUAL annotations
The top 36 of 36 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
tachykinin receptor activity
|
33,123.05 | 100.00 | 39 | 39 |
positive regulation of flagellated sperm motility
|
5,993.70 | 15.20 | 19 | 105 |
tachykinin receptor signaling pathway
|
5,520.51 | 7.81 | 5 | 30 |
sperm midpiece
|
1,700.91 | 4.87 | 19 | 370 |
detection of abiotic stimulus
|
8,280.76 | 2.38 | 1 | 4 |
sperm head
|
1,122.82 | 2.08 | 2 | 59 |
positive regulation of uterine smooth muscle contraction
|
2,760.25 | 2.00 | 1 | 12 |
substance K receptor activity
|
2,365.93 | 1.92 | 1 | 14 |
substance P receptor activity
|
1,840.17 | 1.79 | 1 | 18 |
positive regulation of sensory perception of pain
|
1,440.13 | 1.64 | 1 | 23 |
Totals | 172 | 262811 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2011-11-16 | Deleted | DEFINITION | Combining with tachykinin to initiate a change in cell activity. |
2011-11-16 | Added | DEFINITION | Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein. |
2010-06-15 | Added | RELATION | part of GO:0007217 (tachykinin receptor signaling pathway) |
2010-06-14 | Deleted | RELATION | part of GO:0007217 (tachykinin receptor signaling pathway) |
2010-06-08 | Added | RELATION | part of GO:0007217 (tachykinin receptor signaling pathway) |
2008-05-13 | Added | DEFINITION | Combining with tachykinin to initiate a change in cell activity. |
2008-05-12 | Deleted | DEFINITION | Combining with tachykinin to initiate a change in cell activity. |
2008-04-01 | Updated | RELATION | is a GO:0008188 (neuropeptide receptor activity) |
2004-01-03 | Updated | DEFINITION | Combining with tachykinin to initiate a change in cell activity. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | tachykinin receptor activity |
2002-02-06 | Updated | TERM | tachykinin receptor |
2001-04-03 | Updated | TERM | tachykinin receptor |
2001-03-30 | Added | TERM | tachykinin receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-11-16 | Deleted | DEFINITION | Combining with tachykinin to initiate a change in cell activity. |
2011-11-16 | Added | DEFINITION | Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein. |
2008-05-13 | Added | DEFINITION | Combining with tachykinin to initiate a change in cell activity. |
2008-05-12 | Deleted | DEFINITION | Combining with tachykinin to initiate a change in cell activity. |
2004-01-03 | Updated | DEFINITION | Combining with tachykinin to initiate a change in cell activity. |
2003-05-08 | Added | DEFINITION | The function of combining with tachykinin to initiate a change in cell function. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-06-15 | Added | RELATION | part of GO:0007217 (tachykinin receptor signaling pathway) |
2010-06-14 | Deleted | RELATION | part of GO:0007217 (tachykinin receptor signaling pathway) |
2010-06-08 | Added | RELATION | part of GO:0007217 (tachykinin receptor signaling pathway) |
2008-04-01 | Updated | RELATION | is a GO:0008188 (neuropeptide receptor activity) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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