GO:0004998
JSON
transferrin receptor activity
Molecular Function
Definition (GO:0004998 GONUTS page)
Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates. PMID:2678449 PMID:3011819
Ancestor Chart
Ancestor chart for GO:0004998
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR037324 | Transferrin receptor protein 1/2, PA domain |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004998 based on ALL annotations
The top 100 of 143 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
transferrin receptor activity
|
107,286.07 | 100.00 | 1,817 | 1,817 |
transferrin transport
|
74,171.06 | 69.00 | 1,812 | 2,621 |
endocytic iron import into cell
|
63,966.79 | 15.56 | 316 | 530 |
HFE-transferrin receptor complex
|
40,319.17 | 8.26 | 174 | 463 |
melanosome
|
5,868.11 | 5.40 | 1,481 | 27,077 |
receptor internalization
|
5,691.98 | 5.24 | 1,460 | 27,519 |
multicellular organismal-level iron ion homeostasis
|
8,260.04 | 4.47 | 175 | 2,273 |
positive regulation of protein maturation
|
60,742.85 | 4.10 | 77 | 136 |
positive regulation of peptide hormone secretion
|
14,218.64 | 3.32 | 77 | 581 |
positive regulation of isotype switching
|
6,483.30 | 3.03 | 104 | 1,721 |
Totals | 19277 | 32884827 |
No co-occurrence statistics for GO:0004998 based on MANUAL annotations
The top 85 of 85 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
transferrin receptor activity
|
71,766.61 | 100.00 | 18 | 18 |
HFE-transferrin receptor complex
|
25,329.39 | 20.69 | 6 | 17 |
transferrin transport
|
15,658.17 | 19.67 | 12 | 55 |
positive regulation of isotype switching
|
8,970.83 | 11.36 | 10 | 80 |
positive regulation of protein maturation
|
35,883.31 | 10.00 | 2 | 4 |
endocytic iron import into cell
|
11,961.10 | 7.14 | 2 | 12 |
multicellular organismal-level iron ion homeostasis
|
3,203.87 | 4.00 | 5 | 112 |
NADH regeneration
|
7,974.07 | 3.85 | 1 | 9 |
positive regulation of B cell proliferation
|
2,400.22 | 3.26 | 10 | 299 |
postsynaptic recycling endosome membrane
|
5,126.19 | 3.23 | 1 | 14 |
Totals | 260 | 435724 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2011-08-04 | Added | DEFINITION | Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates. |
2011-08-04 | Deleted | RELATION | is a GO:0004888 (transmembrane signaling receptor activity) |
2011-08-04 | Added | RELATION | is a GO:0038024 (cargo receptor activity) |
2011-08-04 | Deleted | DEFINITION | Combining with transferrin to initiate a change in cell activity. |
2008-05-13 | Added | DEFINITION | Combining with transferrin to initiate a change in cell activity. |
2008-05-12 | Deleted | DEFINITION | Combining with transferrin to initiate a change in cell activity. |
2008-04-01 | Updated | RELATION | is a GO:0004888 (transmembrane signaling receptor activity) |
2005-03-22 | Added | DEFINITION | Combining with transferrin to initiate a change in cell activity. |
2003-03-19 | Updated | TERM | transferrin receptor activity |
2002-02-06 | Updated | TERM | transferrin receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | transferrin receptor activity |
2002-02-06 | Updated | TERM | transferrin receptor |
2001-04-03 | Updated | TERM | transferrin receptor |
2001-03-30 | Added | TERM | transferrin receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-08-04 | Added | DEFINITION | Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates. |
2011-08-04 | Deleted | DEFINITION | Combining with transferrin to initiate a change in cell activity. |
2008-05-13 | Added | DEFINITION | Combining with transferrin to initiate a change in cell activity. |
2008-05-12 | Deleted | DEFINITION | Combining with transferrin to initiate a change in cell activity. |
2005-03-22 | Added | DEFINITION | Combining with transferrin to initiate a change in cell activity. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-08-04 | Deleted | RELATION | is a GO:0004888 (transmembrane signaling receptor activity) |
2011-08-04 | Added | RELATION | is a GO:0038024 (cargo receptor activity) |
2008-04-01 | Updated | RELATION | is a GO:0004888 (transmembrane signaling receptor activity) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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