This term is obsolete.

GO:0004998 JSON

transferrin receptor activity

Molecular Function

Definition (GO:0004998 GONUTS page)

Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates. PMID:2678449 PMID:3011819

1,837 annotations

Ancestor Chart

Ancestor chart for GO:0004998
Chart options
Ancestor chart

Cross-references

Database ID Description
InterPro IPR037324 Transferrin receptor protein 1/2, PA domain

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004998 based on ALL annotations
The top 100 of 143 co-occurring terms
Co-occurring Term PR S% #Together #Compared
transferrin receptor activity
107,286.07 100.00 1,817 1,817
transferrin transport
74,171.06 69.00 1,812 2,621
endocytic iron import into cell
63,966.79 15.56 316 530
HFE-transferrin receptor complex
40,319.17 8.26 174 463
melanosome
5,868.11 5.40 1,481 27,077
receptor internalization
5,691.98 5.24 1,460 27,519
multicellular organismal-level iron ion homeostasis
8,260.04 4.47 175 2,273
positive regulation of protein maturation
60,742.85 4.10 77 136
positive regulation of peptide hormone secretion
14,218.64 3.32 77 581
positive regulation of isotype switching
6,483.30 3.03 104 1,721
Totals 19277 32884827
No co-occurrence statistics for GO:0004998 based on MANUAL annotations
The top 85 of 85 co-occurring terms
Co-occurring Term PR S% #Together #Compared
transferrin receptor activity
71,766.61 100.00 18 18
HFE-transferrin receptor complex
25,329.39 20.69 6 17
transferrin transport
15,658.17 19.67 12 55
positive regulation of isotype switching
8,970.83 11.36 10 80
positive regulation of protein maturation
35,883.31 10.00 2 4
endocytic iron import into cell
11,961.10 7.14 2 12
multicellular organismal-level iron ion homeostasis
3,203.87 4.00 5 112
NADH regeneration
7,974.07 3.85 1 9
positive regulation of B cell proliferation
2,400.22 3.26 10 299
postsynaptic recycling endosome membrane
5,126.19 3.23 1 14
Totals 260 435724

Change Log

Timestamp Action Category Detail
2011-08-04 Added DEFINITION Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.
2011-08-04 Deleted RELATION is a GO:0004888 (transmembrane signaling receptor activity)
2011-08-04 Added RELATION is a GO:0038024 (cargo receptor activity)
2011-08-04 Deleted DEFINITION Combining with transferrin to initiate a change in cell activity.
2008-05-13 Added DEFINITION Combining with transferrin to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with transferrin to initiate a change in cell activity.
2008-04-01 Updated RELATION is a GO:0004888 (transmembrane signaling receptor activity)
2005-03-22 Added DEFINITION Combining with transferrin to initiate a change in cell activity.
2003-03-19 Updated TERM transferrin receptor activity
2002-02-06 Updated TERM transferrin receptor
Timestamp Action Category Detail
2003-03-19 Updated TERM transferrin receptor activity
2002-02-06 Updated TERM transferrin receptor
2001-04-03 Updated TERM transferrin receptor
2001-03-30 Added TERM transferrin receptor
Timestamp Action Category Detail
2011-08-04 Added DEFINITION Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.
2011-08-04 Deleted DEFINITION Combining with transferrin to initiate a change in cell activity.
2008-05-13 Added DEFINITION Combining with transferrin to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with transferrin to initiate a change in cell activity.
2005-03-22 Added DEFINITION Combining with transferrin to initiate a change in cell activity.
Timestamp Action Category Detail
2011-08-04 Deleted RELATION is a GO:0004888 (transmembrane signaling receptor activity)
2011-08-04 Added RELATION is a GO:0038024 (cargo receptor activity)
2008-04-01 Updated RELATION is a GO:0004888 (transmembrane signaling receptor activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.