This term is obsolete.

GO:0005132 JSON

type I interferon receptor binding

Molecular Function

Definition (GO:0005132 GONUTS page)

Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). PMID:17502368

235 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
interferon-alpha/beta receptor binding exact
IFNAR binding related
IFNAR1 binding narrow
IFNAR2 binding narrow
interferon-alpha/beta receptor ligand narrow
interferon-alpha/beta narrow

Ancestor Chart

Ancestor chart for GO:0005132
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5Y865 10116 A0A8I5Y865_RAT GO:0044877 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8J8YB21 10116 A0A8J8YB21_RAT GO:0044877 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B2GUV6 10116 B2GUV6_RAT GO:0044877 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O95970 9606 LGI1_HUMAN GO:0005102 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P52164 10116 MAX_RAT GO:0044877 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:7791753

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005132 based on ALL annotations
The top 79 of 79 co-occurring terms
Co-occurring Term PR S% #Together #Compared
type I interferon receptor binding
898,335.40 100.00 217 217
natural killer cell activation involved in immune response
270,601.90 27.92 172 571
B cell activation involved in immune response
206,116.75 21.68 173 754
T cell activation involved in immune response
100,857.50 10.91 172 1,532
response to exogenous dsRNA
65,292.55 7.14 174 2,394
type I interferon-mediated signaling pathway
49,307.34 5.42 178 3,243
negative regulation of Lewy body formation
760,129.94 5.02 11 13
negative regulation of T-helper 2 cell cytokine production
52,330.22 2.92 12 206
cytokine receptor binding
22,215.25 2.47 217 8,775
humoral immune response
21,106.61 2.34 178 7,576
Totals 3212 68885530
No co-occurrence statistics for GO:0005132 based on MANUAL annotations
The top 74 of 74 co-occurring terms
Co-occurring Term PR S% #Together #Compared
type I interferon receptor binding
7,424.13 100.00 174 174
B cell activation involved in immune response
6,515.05 86.87 172 196
natural killer cell activation involved in immune response
6,229.03 83.09 172 205
T cell activation involved in immune response
5,342.89 71.37 172 239
response to exogenous dsRNA
4,756.94 63.84 173 270
humoral immune response
3,301.73 44.36 173 389
type I interferon-mediated signaling pathway
2,642.75 35.52 173 486
adaptive immune response
2,396.22 32.22 173 536
cytokine activity
598.22 8.05 173 2,147
cellular response to virus
435.29 3.89 18 307
Totals 1909 235461

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
2021-05-24 Added DEFINITION Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
2018-02-18 Deleted RELATION is a GO:0032403 (protein complex binding)
2018-02-18 Added RELATION is a GO:0044877 (protein-containing complex binding)
2013-11-29 Added SYNONYM IFNAR2 binding
2013-11-29 Added SYNONYM interferon-alpha/beta receptor binding
2013-11-29 Added SYNONYM IFNAR binding
2013-11-29 Added RELATION is a GO:0032403 (protein complex binding)
2013-11-29 Added SYNONYM IFNAR1 binding
2013-11-29 Updated TERM type I interferon receptor binding
Timestamp Action Category Detail
2013-11-29 Updated TERM type I interferon receptor binding
2003-06-10 Updated TERM interferon-alpha/beta receptor binding
2003-05-30 Updated TERM interferon-alpha/beta receptor binding activity
2003-03-19 Updated TERM interferon-alpha/beta receptor ligand activity
2002-02-06 Updated TERM interferon-alpha/beta receptor ligand
2001-04-03 Updated TERM interferon-alpha/beta receptor ligand
2001-03-30 Added TERM interferon-alpha/beta receptor ligand
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
2021-05-24 Added DEFINITION Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
2013-11-29 Added SYNONYM IFNAR2 binding
2013-11-29 Added SYNONYM interferon-alpha/beta receptor binding
2013-11-29 Added SYNONYM IFNAR binding
2013-11-29 Added SYNONYM IFNAR1 binding
2013-11-29 Added DEFINITION Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
2013-11-29 Deleted DEFINITION Interacting selectively and non-covalently with the interferon-alpha/beta receptor.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with the interferon-alpha/beta receptor.
2009-07-03 Deleted DEFINITION Interacting selectively with the interferon-alpha/beta receptor.
2008-05-13 Added DEFINITION Interacting selectively with the interferon-alpha/beta receptor.
2008-05-12 Deleted DEFINITION Interacting selectively with the interferon-alpha/beta receptor.
2007-08-09 Deleted SYNONYM interferon-alpha/beta
2007-08-09 Added SYNONYM interferon-alpha/beta receptor ligand
2007-08-09 Added SYNONYM interferon-alpha/beta
2007-08-09 Deleted SYNONYM interferon-alpha/beta receptor ligand
2004-04-19 Added SYNONYM interferon-alpha/beta
2004-04-16 Deleted SYNONYM interferon-alpha/beta
2003-07-25 Added DEFINITION Interacting selectively with the interferon-alpha/beta receptor.
2003-05-30 Added SYNONYM interferon-alpha/beta receptor ligand
2001-03-30 Added SYNONYM interferon-alpha/beta
Timestamp Action Category Detail
2018-02-18 Deleted RELATION is a GO:0032403 (protein complex binding)
2018-02-18 Added RELATION is a GO:0044877 (protein-containing complex binding)
2013-11-29 Added RELATION is a GO:0032403 (protein complex binding)
2008-04-01 Updated RELATION is a GO:0005126 (cytokine receptor binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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