GO:0005132
JSON
type I interferon receptor binding
Molecular Function
Definition (GO:0005132 GONUTS page)
Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). PMID:17502368
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
interferon-alpha/beta receptor binding | exact |
IFNAR binding | related |
IFNAR1 binding | narrow |
IFNAR2 binding | narrow |
interferon-alpha/beta receptor ligand | narrow |
interferon-alpha/beta | narrow |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5Y865 | 10116 | A0A8I5Y865_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8J8YB21 | 10116 | A0A8J8YB21_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B2GUV6 | 10116 | B2GUV6_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O95970 | 9606 | LGI1_HUMAN | GO:0005102 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223 | |
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P52164 | 10116 | MAX_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:7791753 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005132 based on ALL annotations
The top 80 of 80 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
type I interferon receptor binding
|
805,507.60 | 100.00 | 246 | 246 |
natural killer cell activation involved in immune response
|
268,948.53 | 31.07 | 201 | 602 |
B cell activation involved in immune response
|
205,704.84 | 24.19 | 202 | 791 |
T cell activation involved in immune response
|
102,407.98 | 12.36 | 201 | 1,581 |
response to exogenous dsRNA
|
66,933.30 | 8.17 | 203 | 2,443 |
type I interferon-mediated signaling pathway
|
50,313.84 | 6.17 | 207 | 3,314 |
negative regulation of Lewy body formation
|
681,583.25 | 4.44 | 11 | 13 |
cytokine receptor binding
|
22,142.68 | 2.75 | 246 | 8,949 |
negative regulation of T-helper 2 cell cytokine production
|
46,922.77 | 2.73 | 12 | 206 |
humoral immune response
|
21,545.43 | 2.66 | 207 | 7,739 |
Totals | 3772 | 70827919 |
No co-occurrence statistics for GO:0005132 based on MANUAL annotations
The top 74 of 74 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
type I interferon receptor binding
|
6,953.36 | 100.00 | 203 | 203 |
B cell activation involved in immune response
|
6,076.64 | 86.64 | 201 | 230 |
natural killer cell activation involved in immune response
|
5,922.15 | 84.45 | 201 | 236 |
T cell activation involved in immune response
|
5,157.29 | 73.63 | 201 | 271 |
response to exogenous dsRNA
|
4,681.93 | 67.11 | 202 | 300 |
humoral immune response
|
3,251.34 | 46.65 | 202 | 432 |
type I interferon-mediated signaling pathway
|
2,586.70 | 37.13 | 202 | 543 |
adaptive immune response
|
2,302.59 | 33.06 | 202 | 610 |
cytokine activity
|
524.10 | 7.53 | 202 | 2,680 |
cellular response to virus
|
418.60 | 3.72 | 18 | 299 |
Totals | 2198 | 182784 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). |
2021-05-24 | Added | DEFINITION | Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). |
2018-02-18 | Added | RELATION | is a GO:0044877 (protein-containing complex binding) |
2018-02-18 | Deleted | RELATION | is a GO:0032403 (protein complex binding) |
2013-11-29 | Added | SYNONYM | interferon-alpha/beta receptor binding |
2013-11-29 | Added | SYNONYM | IFNAR2 binding |
2013-11-29 | Added | RELATION | is a GO:0032403 (protein complex binding) |
2013-11-29 | Deleted | DEFINITION | Interacting selectively and non-covalently with the interferon-alpha/beta receptor. |
2013-11-29 | Added | SYNONYM | IFNAR1 binding |
2013-11-29 | Added | SYNONYM | IFNAR binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-11-29 | Updated | TERM | type I interferon receptor binding |
2003-06-10 | Updated | TERM | interferon-alpha/beta receptor binding |
2003-05-30 | Updated | TERM | interferon-alpha/beta receptor binding activity |
2003-03-19 | Updated | TERM | interferon-alpha/beta receptor ligand activity |
2002-02-06 | Updated | TERM | interferon-alpha/beta receptor ligand |
2001-04-03 | Updated | TERM | interferon-alpha/beta receptor ligand |
2001-03-30 | Added | TERM | interferon-alpha/beta receptor ligand |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). |
2021-05-24 | Added | DEFINITION | Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). |
2013-11-29 | Added | SYNONYM | interferon-alpha/beta receptor binding |
2013-11-29 | Added | SYNONYM | IFNAR2 binding |
2013-11-29 | Deleted | DEFINITION | Interacting selectively and non-covalently with the interferon-alpha/beta receptor. |
2013-11-29 | Added | SYNONYM | IFNAR1 binding |
2013-11-29 | Added | SYNONYM | IFNAR binding |
2013-11-29 | Added | DEFINITION | Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with the interferon-alpha/beta receptor. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with the interferon-alpha/beta receptor. |
2008-05-13 | Added | DEFINITION | Interacting selectively with the interferon-alpha/beta receptor. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with the interferon-alpha/beta receptor. |
2007-08-09 | Deleted | SYNONYM | interferon-alpha/beta |
2007-08-09 | Added | SYNONYM | interferon-alpha/beta |
2007-08-09 | Added | SYNONYM | interferon-alpha/beta receptor ligand |
2007-08-09 | Deleted | SYNONYM | interferon-alpha/beta receptor ligand |
2004-04-19 | Added | SYNONYM | interferon-alpha/beta |
2004-04-16 | Deleted | SYNONYM | interferon-alpha/beta |
2003-07-25 | Added | DEFINITION | Interacting selectively with the interferon-alpha/beta receptor. |
2003-05-30 | Added | SYNONYM | interferon-alpha/beta receptor ligand |
2001-03-30 | Added | SYNONYM | interferon-alpha/beta |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-02-18 | Added | RELATION | is a GO:0044877 (protein-containing complex binding) |
2018-02-18 | Deleted | RELATION | is a GO:0032403 (protein complex binding) |
2013-11-29 | Added | RELATION | is a GO:0032403 (protein complex binding) |
2008-04-01 | Updated | RELATION | is a GO:0005126 (cytokine receptor binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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