GO:0005178
JSON
integrin binding
Molecular Function
Definition (GO:0005178 GONUTS page)
Binding to an integrin.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
integrin ligand | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005178
Child Term | Relationship to GO:0005178 |
---|---|
integrin binding involved in cell-matrix adhesion
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5Y865 | 10116 | A0A8I5Y865_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8J8YB21 | 10116 | A0A8J8YB21_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B2GUV6 | 10116 | B2GUV6_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O95970 | 9606 | LGI1_HUMAN | GO:0005102 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223 | |
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P52164 | 10116 | MAX_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:7791753 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR033292 | Thy-1 membrane glycoprotein |
InterPro | IPR037904 | Nischarin, PX domain |
InterPro | IPR047012 | Intercellular adhesion molecule/vascular cell adhesion molecule |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005178 based on ALL annotations
The top 100 of 3,241 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
integrin binding
|
2,273.87 | 100.00 | 85,730 | 85,730 |
cell adhesion mediated by integrin
|
2,248.00 | 48.48 | 41,799 | 42,280 |
integrin-mediated signaling pathway
|
1,564.90 | 46.17 | 50,053 | 72,729 |
cell-matrix adhesion
|
1,463.34 | 43.47 | 49,086 | 76,274 |
integrin complex
|
1,925.07 | 42.12 | 39,097 | 46,181 |
cell-cell adhesion
|
535.50 | 19.94 | 48,501 | 205,947 |
focal adhesion
|
539.73 | 15.38 | 26,066 | 109,815 |
cell adhesion
|
258.13 | 10.98 | 65,948 | 580,935 |
external side of plasma membrane
|
302.82 | 10.50 | 28,442 | 213,567 |
positive regulation of cell differentiation
|
1,430.43 | 8.86 | 8,010 | 12,733 |
Totals | 696230 | 7553533 |
No co-occurrence statistics for GO:0005178 based on MANUAL annotations
The top 100 of 2,894 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
integrin binding
|
770.76 | 100.00 | 1,676 | 1,676 |
integrin-mediated signaling pathway
|
528.05 | 34.79 | 694 | 1,013 |
integrin complex
|
761.15 | 32.92 | 554 | 561 |
cell-matrix adhesion
|
410.04 | 26.60 | 582 | 1,094 |
cell adhesion mediated by integrin
|
673.86 | 25.96 | 452 | 517 |
cell-cell adhesion
|
170.31 | 16.74 | 685 | 3,100 |
focal adhesion
|
129.57 | 11.05 | 409 | 2,433 |
cell adhesion
|
87.66 | 8.01 | 357 | 3,139 |
external side of plasma membrane
|
61.01 | 6.56 | 464 | 5,862 |
positive regulation of cell differentiation
|
255.56 | 6.48 | 125 | 377 |
Totals | 11200 | 101709 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_chembl | 296 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to an integrin. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with an integrin. |
2018-02-18 | Added | RELATION | is a GO:0044877 (protein-containing complex binding) |
2018-02-18 | Deleted | RELATION | is a GO:0032403 (protein complex binding) |
2015-05-19 | Added | SUBSET | goslim_chembl |
2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
2015-05-11 | Added | SUBSET | goslim_ChEMBL |
2014-05-11 | Added | RELATION | is a GO:0050839 (cell adhesion molecule binding) |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with an integrin. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with an integrin. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | integrin binding |
2003-03-19 | Updated | TERM | integrin binding activity |
2002-07-23 | Updated | TERM | integrin binding |
2002-02-06 | Updated | TERM | integrin ligand |
2001-04-03 | Updated | TERM | integrin ligand |
2001-03-30 | Added | TERM | integrin ligand |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to an integrin. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with an integrin. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with an integrin. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with an integrin. |
2008-05-13 | Added | DEFINITION | Interacting selectively with an integrin. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with an integrin. |
2007-08-09 | Added | SYNONYM | integrin ligand |
2007-08-09 | Deleted | SYNONYM | integrin ligand |
2003-03-26 | Updated | DEFINITION | Interacting selectively with an integrin. |
2002-11-27 | Added | DEFINITION | Interacting selectively and stoichiometrically with an integrin. |
2002-07-23 | Added | SYNONYM | integrin ligand |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-02-18 | Added | RELATION | is a GO:0044877 (protein-containing complex binding) |
2018-02-18 | Deleted | RELATION | is a GO:0032403 (protein complex binding) |
2014-05-11 | Added | RELATION | is a GO:0050839 (cell adhesion molecule binding) |
2008-04-01 | Updated | RELATION | is a GO:0005102 (signaling receptor binding) |
2008-04-01 | Updated | RELATION | is a GO:0032403 (protein complex binding) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-05-19 | Added | SUBSET | goslim_chembl |
2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
2015-05-11 | Added | SUBSET | goslim_ChEMBL |
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