This term is obsolete.

GO:0005178 JSON

integrin binding

Molecular Function

Definition (GO:0005178 GONUTS page)

Binding to an integrin.

89,268 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
integrin ligand narrow

Ancestor Chart

Ancestor chart for GO:0005178
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005178

Child Term Relationship to
GO:0005178
integrin binding involved in cell-matrix adhesion
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5Y865 10116 A0A8I5Y865_RAT GO:0044877 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8J8YB21 10116 A0A8J8YB21_RAT GO:0044877 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B2GUV6 10116 B2GUV6_RAT GO:0044877 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O95970 9606 LGI1_HUMAN GO:0005102 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P52164 10116 MAX_RAT GO:0044877 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:7791753

Cross-references

Database ID Description
InterPro IPR033292 Thy-1 membrane glycoprotein
InterPro IPR037904 Nischarin, PX domain
InterPro IPR047012 Intercellular adhesion molecule/vascular cell adhesion molecule

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005178 based on ALL annotations
The top 100 of 3,243 co-occurring terms
Co-occurring Term PR S% #Together #Compared
integrin binding
2,262.46 100.00 87,584 87,584
cell adhesion mediated by integrin
2,237.48 48.84 43,009 43,489
integrin-mediated signaling pathway
1,574.22 46.69 51,385 73,850
cell-matrix adhesion
1,457.02 43.52 50,190 77,935
integrin complex
1,913.32 42.25 40,098 47,415
cell-cell adhesion
530.03 19.87 49,676 212,046
focal adhesion
545.20 15.54 26,671 110,678
cell adhesion
251.46 10.75 67,018 602,985
external side of plasma membrane
303.16 10.56 29,139 217,464
positive regulation of cell differentiation
1,431.11 8.87 8,194 12,954
Totals 709189 7748220
No co-occurrence statistics for GO:0005178 based on MANUAL annotations
The top 100 of 2,880 co-occurring terms
Co-occurring Term PR S% #Together #Compared
integrin binding
773.44 100.00 1,825 1,825
cell adhesion mediated by integrin
712.30 38.88 734 797
integrin-mediated signaling pathway
534.11 36.26 790 1,144
integrin complex
765.18 35.37 648 655
cell-matrix adhesion
388.38 20.45 468 932
cell-cell adhesion
176.25 17.41 775 3,401
focal adhesion
137.97 11.53 449 2,517
cell adhesion
88.24 8.12 401 3,515
positive regulation of cell differentiation
285.05 7.20 150 407
external side of plasma membrane
62.66 6.75 525 6,480
Totals 12409 110272

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_chembl 296

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with an integrin.
2021-05-24 Added DEFINITION Binding to an integrin.
2018-02-18 Deleted RELATION is a GO:0032403 (protein complex binding)
2018-02-18 Added RELATION is a GO:0044877 (protein-containing complex binding)
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-19 Added SUBSET goslim_chembl
2015-05-11 Added SUBSET goslim_ChEMBL
2014-05-11 Added RELATION is a GO:0050839 (cell adhesion molecule binding)
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with an integrin.
2009-07-03 Deleted DEFINITION Interacting selectively with an integrin.
Timestamp Action Category Detail
2003-06-10 Updated TERM integrin binding
2003-03-19 Updated TERM integrin binding activity
2002-07-23 Updated TERM integrin binding
2002-02-06 Updated TERM integrin ligand
2001-04-03 Updated TERM integrin ligand
2001-03-30 Added TERM integrin ligand
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with an integrin.
2021-05-24 Added DEFINITION Binding to an integrin.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with an integrin.
2009-07-03 Deleted DEFINITION Interacting selectively with an integrin.
2008-05-13 Added DEFINITION Interacting selectively with an integrin.
2008-05-12 Deleted DEFINITION Interacting selectively with an integrin.
2007-08-09 Deleted SYNONYM integrin ligand
2007-08-09 Added SYNONYM integrin ligand
2003-03-26 Updated DEFINITION Interacting selectively with an integrin.
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with an integrin.
2002-07-23 Added SYNONYM integrin ligand
Timestamp Action Category Detail
2018-02-18 Deleted RELATION is a GO:0032403 (protein complex binding)
2018-02-18 Added RELATION is a GO:0044877 (protein-containing complex binding)
2014-05-11 Added RELATION is a GO:0050839 (cell adhesion molecule binding)
2008-04-01 Updated RELATION is a GO:0032403 (protein complex binding)
2008-04-01 Updated RELATION is a GO:0005102 (signaling receptor binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-19 Added SUBSET goslim_chembl
2015-05-11 Added SUBSET goslim_ChEMBL
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.