This term is obsolete.
Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'.

GO:0005234 JSON

extracellularly glutamate-gated ion channel activity

Molecular Function

Definition (GO:0005234 GONUTS page)

Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.

Comments

Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'.

138 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
extracellular-glutamate-gated ion channel activity exact

Ancestor Chart

Ancestor chart for GO:0005234
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005234

Child Term Relationship to
GO:0005234
extracellularly glutamate-gated chloride channel activity
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005234 extracellularly glutamate-gated ion channel activity Only in Taxon 33208 Metazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5ZLE9 10116 A0A8I5ZLE9_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZST4 10116 A0A8I5ZST4_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AI08 10116 A0A8I6AI08_RAT GO:0015267 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0PK00 9606 T120B_HUMAN GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6HVQ8 10116 A6HVQ8_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6J168 10116 A6J168_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6J4P5 10116 A6J4P5_RAT GO:0015267 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K7I4 10116 A6K7I4_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K7I4 10116 A6K7I4_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6QPF8 9913 T120B_BOVIN GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005234 based on ALL annotations
The top 100 of 254 co-occurring terms
Co-occurring Term PR S% #Together #Compared
extracellularly glutamate-gated ion channel activity
1,725,121.90 100.00 113 113
mossy fiber rosette
1,613,101.10 61.02 72 77
detection of cold stimulus involved in thermoception
1,110,078.50 48.05 74 115
kainate selective glutamate receptor activity
398,431.12 22.07 94 407
kainate selective glutamate receptor complex
411,548.70 21.10 73 306
proton binding
784,146.40 11.45 15 33
glutamate-gated calcium ion channel activity
201,903.16 11.14 79 675
regulation of long-term neuronal synaptic plasticity
109,672.70 6.15 74 1,164
regulation of monoatomic cation transmembrane transport
155,169.70 5.96 17 189
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
97,172.20 5.49 77 1,367
Totals 2470 360909
No co-occurrence statistics for GO:0005234 based on MANUAL annotations
The top 100 of 241 co-occurring terms
Co-occurring Term PR S% #Together #Compared
extracellularly glutamate-gated ion channel activity
47,844.41 100.00 27 27
regulation of monoatomic cation transmembrane transport
21,404.08 35.42 17 38
proton binding
23,150.52 34.88 15 31
voltage-gated monoatomic cation channel activity
11,777.09 21.05 16 65
glutamate binding
9,786.36 18.56 18 88
detection of cold stimulus involved in thermoception
19,935.17 14.71 5 12
glutamate-gated receptor activity
7,475.69 12.35 10 64
glutamate-gated calcium ion channel activity
8,320.77 12.31 8 46
positive regulation of excitatory postsynaptic potential
6,069.81 11.81 17 134
ionotropic glutamate receptor signaling pathway
5,681.52 11.31 19 160
Totals 432 7888

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2022-11-08 Added DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
2022-11-08 Deleted DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
2017-11-01 Deleted DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2017-11-01 Updated TERM extracellularly glutamate-gated ion channel activity
2017-11-01 Added SYNONYM extracellular-glutamate-gated ion channel activity
2017-11-01 Added DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
2015-05-11 Deleted DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2015-05-11 Added DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2008-05-13 Added DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
Timestamp Action Category Detail
2017-11-01 Updated TERM extracellularly glutamate-gated ion channel activity
2007-07-11 Updated TERM extracellular-glutamate-gated ion channel activity
2003-03-19 Updated TERM glutamate-gated ion channel activity
2002-02-06 Updated TERM glutamate-gated ion channel
2001-04-03 Updated TERM glutamate-gated ion channel
2001-03-30 Added TERM glutamate-gated ion channel
Timestamp Action Category Detail
2022-11-08 Added DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
2022-11-08 Deleted DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
2017-11-01 Deleted DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2017-11-01 Added SYNONYM extracellular-glutamate-gated ion channel activity
2017-11-01 Added DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
2015-05-11 Deleted DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2015-05-11 Added DEFINITION Enables the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2008-05-13 Added DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2008-05-12 Deleted DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2008-03-11 Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2007-07-27 Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
2003-05-13 Added DEFINITION See comment.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005231 (excitatory extracellular ligand-gated monoatomic ion channel activity)
Timestamp Action Category Detail
2007-07-11 Deleted XREF TC:1.A.10.-.-
2001-03-30 Added XREF TC:1.A.10.-.-
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.