This term is obsolete.

GO:0005384 JSON

manganese ion transmembrane transporter activity

Molecular Function

Definition (GO:0005384 GONUTS page)

Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.

93,513 annotations

Ancestor Chart

Ancestor chart for GO:0005384
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005384

Child Term Relationship to
GO:0005384
calcium:manganese antiporter activity
is_a
ABC-type manganese transporter activity
is_a
manganese:proton antiporter activity
is_a
P-type manganese transporter activity
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A2WLC1 39946 CDT3_ORYSI GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6K7I4 10116 A6K7I4_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7MB71 9913 AT1B4_BOVIN GO:0098662 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein B4YDY0 10090 B4YDY0_MOUSE GO:0006811 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18624921
NOT-qualified manual protein B8B2D0 39946 CDT1_ORYSI GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein D4ABB2 10116 D4ABB2_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q5VRD7 39947 CDT3_ORYSJ GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867
NOT-qualified manual protein Q5VSB5 39947 CDT1_ORYSJ GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867
NOT-qualified manual protein Q6ZG85 39947 NRAT1_ORYSJ GO:0005384 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:20937890
NOT-qualified manual protein Q8CHM1 10116 AQP11_RAT GO:0006811 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000266, ECO:0000314 from these references: GO_REF:0000096, PMID:16650285

Cross-references

Database ID Description
InterPro IPR008217 Ccc1 family
MetaCyc RXN0-16
Reactome R-HSA-8959798

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:29035 manganese(2+)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005384 based on ALL annotations
The top 100 of 683 co-occurring terms
Co-occurring Term PR S% #Together #Compared
manganese ion transmembrane transporter activity
2,137.37 100.00 91,205 91,205
manganese ion transmembrane transport
2,096.05 97.97 91,115 92,911
manganese ion transport
2,076.98 47.75 44,160 45,444
intracellular manganese ion homeostasis
1,727.53 33.29 32,971 40,793
cadmium ion transmembrane transporter activity
993.30 30.97 43,900 94,463
cadmium ion transmembrane transport
988.44 30.87 43,907 94,943
iron ion transmembrane transport
610.76 22.48 46,794 163,758
metal ion transmembrane transporter activity
553.39 21.31 49,839 192,495
metal ion transport
275.91 11.33 43,921 340,245
Golgi calcium ion transport
2,100.44 6.48 5,915 6,019
Totals 804026 83938219
No co-occurrence statistics for GO:0005384 based on MANUAL annotations
The top 100 of 274 co-occurring terms
Co-occurring Term PR S% #Together #Compared
manganese ion transmembrane transporter activity
1,040.93 100.00 1,241 1,241
iron ion transmembrane transporter activity
928.15 38.56 502 563
intracellular manganese ion homeostasis
1,006.94 37.71 474 490
cadmium ion transmembrane transporter activity
950.87 35.36 454 497
manganese ion transport
845.99 34.15 460 566
intracellular sequestering of iron ion
929.79 33.64 435 487
iron ion transmembrane transport
833.48 33.53 454 567
manganese ion transmembrane transport
1,011.61 22.10 276 284
Golgi calcium ion transport
1,017.00 20.45 255 261
Golgi calcium ion homeostasis
1,017.00 20.45 255 261
Totals 7479 277233

Change Log

Timestamp Action Category Detail
2024-09-14 Deleted XREF RHEA:28699
2024-02-24 Added XREF MetaCyc:RXN0-16
2020-06-22 Added XREF RHEA:28699
2019-04-01 Added XREF Reactome:R-HSA-8959798
2019-04-01 Deleted XREF reactome:R-HSA-8959798
2018-12-11 Added XREF reactome:R-HSA-8959798
2017-10-13 Deleted DEFINITION Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other.
2017-10-13 Added DEFINITION Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.
2013-08-29 Deleted RELATION is a GO:0022890 (inorganic cation transmembrane transporter activity)
2010-12-19 Added RELATION is a GO:0022890 (inorganic cation transmembrane transporter activity)
Timestamp Action Category Detail
2010-06-09 Updated TERM manganese ion transmembrane transporter activity
2010-06-08 Updated TERM manganese ion transmembrane transporter activity
2007-07-14 Updated TERM manganese ion transmembrane transporter activity
2003-03-19 Updated TERM manganese ion transporter activity
2002-02-06 Updated TERM manganese ion transporter
2001-04-03 Updated TERM manganese ion transporter
2001-03-30 Added TERM manganese ion transporter
Timestamp Action Category Detail
2017-10-13 Deleted DEFINITION Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other.
2017-10-13 Added DEFINITION Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.
2008-05-13 Added DEFINITION Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other.
2007-07-27 Updated DEFINITION Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other.
2003-03-26 Added DEFINITION Enables the directed movement of manganese (Mn) ions into, out of, within or between cells.
Timestamp Action Category Detail
2013-08-29 Deleted RELATION is a GO:0022890 (inorganic cation transmembrane transporter activity)
2010-12-19 Added RELATION is a GO:0022890 (inorganic cation transmembrane transporter activity)
2010-12-19 Deleted RELATION is a GO:0015082 (di-, tri-valent inorganic cation transmembrane transporter activity)
2010-06-15 Added RELATION part of GO:0071421 (manganese ion transmembrane transport)
2010-06-14 Deleted RELATION part of GO:0071421 (manganese ion transmembrane transport)
2010-06-08 Added RELATION part of GO:0071421 (manganese ion transmembrane transport)
2008-04-01 Updated RELATION is a GO:0015082 (di-, tri-valent inorganic cation transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0046915 (transition metal ion transmembrane transporter activity)
Timestamp Action Category Detail
2024-09-14 Deleted XREF RHEA:28699
2024-02-24 Added XREF MetaCyc:RXN0-16
2020-06-22 Added XREF RHEA:28699
2019-04-01 Added XREF Reactome:R-HSA-8959798
2019-04-01 Deleted XREF reactome:R-HSA-8959798
2018-12-11 Added XREF reactome:R-HSA-8959798
Timestamp Action Category Detail
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