GO:0005412
JSON
D-glucose:sodium symporter activity
Molecular Function
Definition (GO:0005412 GONUTS page)
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in).
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
glucose:sodium symporter activity | exact |
sodium/glucose symporter activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005412
Child Term | Relationship to GO:0005412 |
---|---|
low-affinity D-glucose:sodium symporter activity
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A0G2JW25 | 10116 | A0A0G2JW25_RAT | GO:0055056 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AEN5 | 10116 | A0A8I6AEN5_RAT | GO:0055056 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AVN8 | 10116 | A0A8I6AVN8_RAT | GO:0055056 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6G921 | 10116 | A0A8I6G921_RAT | GO:0055056 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A2WLC1 | 39946 | CDT3_ORYSI | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A4ZYQ5 | 10116 | GTR7_RAT | GO:0055056 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | A6IJT3 | 10116 | A6IJT3_RAT | GO:0055056 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JTK1 | 10116 | A6JTK1_RAT | GO:0055056 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K7I4 | 10116 | A6K7I4_RAT | GO:0034220 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7MB71 | 9913 | AT1B4_BOVIN | GO:0098662 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR042731 | Sodium/myo-inositol cotransporter SMIT |
MetaCyc | RXN-22596 | |
RHEA | 70495 | |
RHEA | 70571 | |
Reactome | R-HSA-189208 | |
Reactome | R-HSA-429613 | |
Reactome | R-HSA-5656356 | |
Reactome | R-HSA-5658163 | |
Reactome | R-HSA-8932955 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:29101 | sodium(1+) |
has_primary_input | CHEBI | CHEBI:4167 | D-glucopyranose |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005412 based on ALL annotations
The top 100 of 161 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
D-glucose:sodium symporter activity
|
7,399.36 | 100.00 | 26,780 | 26,780 |
hexose transmembrane transport
|
4,581.02 | 61.64 | 26,592 | 42,952 |
carbohydrate transmembrane transport
|
1,073.89 | 14.50 | 26,589 | 183,204 |
sodium ion transmembrane transport
|
498.07 | 6.73 | 26,616 | 395,410 |
myo-inositol transport
|
532.45 | 2.60 | 1,047 | 14,550 |
apical plasma membrane
|
175.44 | 2.07 | 3,795 | 160,059 |
sodium ion transport
|
99.00 | 1.28 | 6,003 | 448,661 |
solute:sodium symporter activity
|
347.21 | 0.94 | 312 | 6,649 |
inositol metabolic process
|
79.25 | 0.83 | 940 | 87,766 |
symporter activity
|
49.95 | 0.65 | 3,402 | 504,002 |
Totals | 232594 | 98936979 |
No co-occurrence statistics for GO:0005412 based on MANUAL annotations
The top 69 of 69 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
D-glucose:sodium symporter activity
|
6,721.59 | 100.00 | 210 | 210 |
sodium ion transport
|
680.04 | 8.38 | 69 | 682 |
myo-inositol transport
|
922.57 | 7.25 | 28 | 204 |
renal D-glucose absorption
|
4,481.06 | 4.65 | 10 | 15 |
myo-inositol:sodium symporter activity
|
6,721.59 | 3.33 | 7 | 7 |
inositol metabolic process
|
308.72 | 3.30 | 22 | 479 |
galactose:sodium symporter activity
|
6,721.59 | 2.86 | 6 | 6 |
intestinal D-glucose absorption
|
2,880.68 | 2.75 | 6 | 14 |
myo-inositol transmembrane transporter activity
|
2,240.53 | 2.70 | 6 | 18 |
alpha-glucoside transmembrane transporter activity
|
4,801.13 | 2.36 | 5 | 7 |
Totals | 750 | 313895 |
Change Log
- All changes
- All changes
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- Term
- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-02 | Deleted | RELATION | is a GO:0005355 (obsolete glucose transmembrane transporter activity) |
2024-09-02 | Added | DEFINITION | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in). |
2024-09-02 | Deleted | DEFINITION | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). |
2024-09-02 | Added | RELATION | is a GO:0055056 (D-glucose transmembrane transporter activity) |
2024-09-02 | Updated | TERM | D-glucose:sodium symporter activity |
2024-09-02 | Added | SYNONYM | glucose:sodium symporter activity |
2024-04-05 | Added | XREF | RHEA:70495 |
2024-04-05 | Added | XREF | MetaCyc:RXN-22596 |
2024-04-05 | Added | XREF | RHEA:70571 |
2019-05-04 | Added | XREF | Reactome:R-HSA-5658163 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-02 | Updated | TERM | D-glucose:sodium symporter activity |
2010-06-09 | Updated | TERM | glucose:sodium symporter activity |
2010-06-08 | Updated | TERM | glucose:sodium symporter activity |
2003-03-19 | Updated | TERM | glucose:sodium symporter activity |
2002-02-06 | Updated | TERM | glucose:sodium symporter |
2001-04-03 | Updated | TERM | glucose:sodium symporter |
2001-03-30 | Added | TERM | glucose:sodium symporter |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-02 | Added | DEFINITION | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in). |
2024-09-02 | Deleted | DEFINITION | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). |
2024-09-02 | Added | SYNONYM | glucose:sodium symporter activity |
2017-10-13 | Deleted | DEFINITION | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). |
2017-10-13 | Added | DEFINITION | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). |
2009-07-30 | Deleted | SYNONYM | sodium/glucose symporter |
2009-07-30 | Added | SYNONYM | sodium/glucose symporter activity |
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). |
2008-05-12 | Deleted | DEFINITION | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). |
2007-08-09 | Deleted | SYNONYM | sodium/glucose symporter |
2007-08-09 | Added | SYNONYM | sodium/glucose symporter |
2007-07-27 | Updated | DEFINITION | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). |
2004-04-19 | Added | SYNONYM | sodium/glucose symporter |
2004-04-16 | Deleted | SYNONYM | sodium/glucose symporter |
2003-03-26 | Added | DEFINITION | Catalysis of the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). |
2001-03-30 | Added | SYNONYM | sodium/glucose symporter |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-02 | Deleted | RELATION | is a GO:0005355 (obsolete glucose transmembrane transporter activity) |
2024-09-02 | Added | RELATION | is a GO:0055056 (D-glucose transmembrane transporter activity) |
2018-02-09 | Added | RELATION | is a GO:0005402 (carbohydrate:monoatomic cation symporter activity) |
2008-04-01 | Updated | RELATION | is a GO:0005355 (obsolete glucose transmembrane transporter activity) |
2008-04-01 | Updated | RELATION | is a GO:0015370 (solute:sodium symporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-05 | Added | XREF | RHEA:70495 |
2024-04-05 | Added | XREF | MetaCyc:RXN-22596 |
2024-04-05 | Added | XREF | RHEA:70571 |
2019-05-04 | Added | XREF | Reactome:R-HSA-5658163 |
2019-05-04 | Added | XREF | Reactome:R-HSA-5656356 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5656356 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5658163 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5656356 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5658163 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5656356 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5658163 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5658163 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5656356 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5656356 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5658163 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5656356 |
2019-04-01 | Added | XREF | Reactome:R-HSA-8932955 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-429613 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-189208 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-8932955 |
2019-04-01 | Added | XREF | Reactome:R-HSA-189208 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5658163 |
2019-04-01 | Added | XREF | Reactome:R-HSA-429613 |
2018-12-11 | Added | XREF | reactome:R-HSA-189208 |
2018-12-11 | Added | XREF | reactome:R-HSA-8932955 |
2018-12-11 | Added | XREF | reactome:R-HSA-429613 |
2007-07-11 | Deleted | XREF | TC:2.A.21.3.- |
2001-03-30 | Added | XREF | TC:2.A.21.3.- |
Timestamp | Action | Category | Detail |
---|
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