This term is obsolete.

GO:0005412 JSON

D-glucose:sodium symporter activity

Molecular Function

Definition (GO:0005412 GONUTS page)

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in).

26,862 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
glucose:sodium symporter activity exact
sodium/glucose symporter activity exact

Ancestor Chart

Ancestor chart for GO:0005412
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005412

Child Term Relationship to
GO:0005412
low-affinity D-glucose:sodium symporter activity
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2JW25 10116 A0A0G2JW25_RAT GO:0055056 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AEN5 10116 A0A8I6AEN5_RAT GO:0055056 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AVN8 10116 A0A8I6AVN8_RAT GO:0055056 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6G921 10116 A0A8I6G921_RAT GO:0055056 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A2WLC1 39946 CDT3_ORYSI GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A4ZYQ5 10116 GTR7_RAT GO:0055056 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein A6IJT3 10116 A6IJT3_RAT GO:0055056 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JTK1 10116 A6JTK1_RAT GO:0055056 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K7I4 10116 A6K7I4_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7MB71 9913 AT1B4_BOVIN GO:0098662 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024

Cross-references

Database ID Description
InterPro IPR042731 Sodium/myo-inositol cotransporter SMIT
MetaCyc RXN-22596
RHEA 70495
RHEA 70571
Reactome R-HSA-189208
Reactome R-HSA-429613
Reactome R-HSA-5656356
Reactome R-HSA-5658163
Reactome R-HSA-8932955

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:29101 sodium(1+)
has_primary_input CHEBI CHEBI:4167 D-glucopyranose

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005412 based on ALL annotations
The top 100 of 161 co-occurring terms
Co-occurring Term PR S% #Together #Compared
D-glucose:sodium symporter activity
7,399.36 100.00 26,780 26,780
hexose transmembrane transport
4,581.02 61.64 26,592 42,952
carbohydrate transmembrane transport
1,073.89 14.50 26,589 183,204
sodium ion transmembrane transport
498.07 6.73 26,616 395,410
myo-inositol transport
532.45 2.60 1,047 14,550
apical plasma membrane
175.44 2.07 3,795 160,059
sodium ion transport
99.00 1.28 6,003 448,661
solute:sodium symporter activity
347.21 0.94 312 6,649
inositol metabolic process
79.25 0.83 940 87,766
symporter activity
49.95 0.65 3,402 504,002
Totals 232594 98936979
No co-occurrence statistics for GO:0005412 based on MANUAL annotations
The top 69 of 69 co-occurring terms
Co-occurring Term PR S% #Together #Compared
D-glucose:sodium symporter activity
6,721.59 100.00 210 210
sodium ion transport
680.04 8.38 69 682
myo-inositol transport
922.57 7.25 28 204
renal D-glucose absorption
4,481.06 4.65 10 15
myo-inositol:sodium symporter activity
6,721.59 3.33 7 7
inositol metabolic process
308.72 3.30 22 479
galactose:sodium symporter activity
6,721.59 2.86 6 6
intestinal D-glucose absorption
2,880.68 2.75 6 14
myo-inositol transmembrane transporter activity
2,240.53 2.70 6 18
alpha-glucoside transmembrane transporter activity
4,801.13 2.36 5 7
Totals 750 313895

Change Log

Timestamp Action Category Detail
2024-09-02 Deleted RELATION is a GO:0005355 (obsolete glucose transmembrane transporter activity)
2024-09-02 Added DEFINITION Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in).
2024-09-02 Deleted DEFINITION Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
2024-09-02 Added RELATION is a GO:0055056 (D-glucose transmembrane transporter activity)
2024-09-02 Updated TERM D-glucose:sodium symporter activity
2024-09-02 Added SYNONYM glucose:sodium symporter activity
2024-04-05 Added XREF RHEA:70495
2024-04-05 Added XREF MetaCyc:RXN-22596
2024-04-05 Added XREF RHEA:70571
2019-05-04 Added XREF Reactome:R-HSA-5658163
Timestamp Action Category Detail
2024-09-02 Updated TERM D-glucose:sodium symporter activity
2010-06-09 Updated TERM glucose:sodium symporter activity
2010-06-08 Updated TERM glucose:sodium symporter activity
2003-03-19 Updated TERM glucose:sodium symporter activity
2002-02-06 Updated TERM glucose:sodium symporter
2001-04-03 Updated TERM glucose:sodium symporter
2001-03-30 Added TERM glucose:sodium symporter
Timestamp Action Category Detail
2024-09-02 Added DEFINITION Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in).
2024-09-02 Deleted DEFINITION Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
2024-09-02 Added SYNONYM glucose:sodium symporter activity
2017-10-13 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
2017-10-13 Added DEFINITION Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
2009-07-30 Deleted SYNONYM sodium/glucose symporter
2009-07-30 Added SYNONYM sodium/glucose symporter activity
2008-05-13 Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
2007-08-09 Deleted SYNONYM sodium/glucose symporter
2007-08-09 Added SYNONYM sodium/glucose symporter
2007-07-27 Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
2004-04-19 Added SYNONYM sodium/glucose symporter
2004-04-16 Deleted SYNONYM sodium/glucose symporter
2003-03-26 Added DEFINITION Catalysis of the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
2001-03-30 Added SYNONYM sodium/glucose symporter
Timestamp Action Category Detail
2024-09-02 Deleted RELATION is a GO:0005355 (obsolete glucose transmembrane transporter activity)
2024-09-02 Added RELATION is a GO:0055056 (D-glucose transmembrane transporter activity)
2018-02-09 Added RELATION is a GO:0005402 (carbohydrate:monoatomic cation symporter activity)
2008-04-01 Updated RELATION is a GO:0005355 (obsolete glucose transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0015370 (solute:sodium symporter activity)
Timestamp Action Category Detail
2024-04-05 Added XREF RHEA:70495
2024-04-05 Added XREF MetaCyc:RXN-22596
2024-04-05 Added XREF RHEA:70571
2019-05-04 Added XREF Reactome:R-HSA-5658163
2019-05-04 Added XREF Reactome:R-HSA-5656356
2019-04-30 Deleted XREF Reactome:R-HSA-5656356
2019-04-30 Deleted XREF Reactome:R-HSA-5658163
2019-04-29 Added XREF Reactome:R-HSA-5656356
2019-04-29 Added XREF Reactome:R-HSA-5658163
2019-04-28 Deleted XREF Reactome:R-HSA-5656356
2019-04-28 Deleted XREF Reactome:R-HSA-5658163
2019-04-27 Added XREF Reactome:R-HSA-5658163
2019-04-27 Added XREF Reactome:R-HSA-5656356
2019-04-23 Deleted XREF Reactome:R-HSA-5656356
2019-04-23 Deleted XREF Reactome:R-HSA-5658163
2019-04-01 Added XREF Reactome:R-HSA-5656356
2019-04-01 Added XREF Reactome:R-HSA-8932955
2019-04-01 Deleted XREF reactome:R-HSA-429613
2019-04-01 Deleted XREF reactome:R-HSA-189208
2019-04-01 Deleted XREF reactome:R-HSA-8932955
2019-04-01 Added XREF Reactome:R-HSA-189208
2019-04-01 Added XREF Reactome:R-HSA-5658163
2019-04-01 Added XREF Reactome:R-HSA-429613
2018-12-11 Added XREF reactome:R-HSA-189208
2018-12-11 Added XREF reactome:R-HSA-8932955
2018-12-11 Added XREF reactome:R-HSA-429613
2007-07-11 Deleted XREF TC:2.A.21.3.-
2001-03-30 Added XREF TC:2.A.21.3.-
Timestamp Action Category Detail
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