This term is obsolete.

GO:0005537 JSON

D-mannose binding

Molecular Function

Definition (GO:0005537 GONUTS page)

Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.

15,117 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
mannose binding broad
mannose binding lectin related

Ancestor Chart

Ancestor chart for GO:0005537
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Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P81508 35024 SLA_CROHD GO:0030246 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:8823201
NOT-qualified manual protein P81509 35024 SLB_CROHD GO:0030246 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:8823201
NOT-qualified manual protein P85004 119829 AMML_ASTMO GO:0005537 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16140255

Cross-references

Database ID Description
InterPro IPR000479 Cation-independent mannose-6-phosphate receptor repeat
InterPro IPR006965 Adenovirus Gp19K
Reactome R-HSA-947991
UniProtKB-KW KW-0465 Mannose-binding

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:37684 mannose

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0005532 obsolete mannose binding lectin consider GO:0005537

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005537 based on ALL annotations
The top 100 of 730 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0005537
D-mannose binding
13,304.69 100.00 14,964 14,964
GO:0030134
COPII-coated ER to Golgi transport vesicle
2,901.58 19.11 9,082 41,644
GO:0005793
endoplasmic reticulum-Golgi intermediate compartment
2,735.25 17.94 8,746 42,542
GO:0007041
lysosomal transport
3,027.74 9.37 2,057 9,039
GO:0006888
endoplasmic reticulum to Golgi vesicle-mediated transport
519.73 3.81 9,082 232,491
GO:0005520
insulin-like growth factor binding
1,017.43 3.24 795 10,396
GO:0001867
complement activation, lectin pathway
1,605.81 2.09 368 3,049
GO:1903028
positive regulation of opsonization
7,246.81 1.69 256 470
GO:0000139
Golgi membrane
187.68 1.40 10,028 710,884
GO:0005581
collagen trimer
222.32 1.39 1,151 68,881
Totals 91318 7320315
No co-occurrence statistics for GO:0005537 based on MANUAL annotations
The top 100 of 317 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0005537
D-mannose binding
3,833.73 100.00 368 368
GO:0042806
fucose binding
2,075.14 14.11 59 109
GO:0038187
pattern recognition receptor activity
374.61 7.61 94 962
GO:0005793
endoplasmic reticulum-Golgi intermediate compartment
319.96 7.58 166 1,989
GO:0030134
COPII-coated ER to Golgi transport vesicle
303.34 7.22 166 2,098
GO:0001867
complement activation, lectin pathway
570.31 3.82 18 121
GO:0120153
calcium-dependent carbohydrate binding
3,833.73 3.80 14 14
GO:0061760
antifungal innate immune response
511.16 3.39 16 120
GO:0005536
D-glucose binding
686.64 2.84 12 67
GO:1903028
positive regulation of opsonization
810.98 2.69 11 52
Totals 2174 71884

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_chembl 296

Change Log

Timestamp Action Category Detail
2024-04-26 Updated TERM D-mannose binding
2024-04-26 Added SYNONYM mannose binding
2021-05-24 Added DEFINITION Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2019-04-01 Added XREF Reactome:R-HSA-947991
2019-04-01 Deleted XREF reactome:R-HSA-947991
2018-12-11 Added XREF reactome:R-HSA-947991
2015-05-19 Added SUBSET goslim_chembl
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-11 Added SUBSET goslim_ChEMBL
Timestamp Action Category Detail
2024-04-26 Updated TERM D-mannose binding
2003-06-10 Updated TERM mannose binding
2003-03-19 Updated TERM mannose binding activity
2002-02-06 Updated TERM mannose binding
2001-04-03 Updated TERM mannose binding
2001-03-30 Added TERM mannose binding
Timestamp Action Category Detail
2024-04-26 Added SYNONYM mannose binding
2021-05-24 Added DEFINITION Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2009-07-03 Deleted DEFINITION Interacting selectively with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2008-05-13 Added DEFINITION Interacting selectively with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2008-05-12 Deleted DEFINITION Interacting selectively with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2007-08-09 Deleted SYNONYM mannose binding lectin
2007-08-09 Added SYNONYM mannose binding lectin
2005-08-10 Added SYNONYM mannose binding lectin
2003-03-26 Updated DEFINITION Interacting selectively with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
Timestamp Action Category Detail
2012-09-21 Added RELATION has part GO:0036350 (mannose-specific flocculation)
2008-04-01 Updated RELATION is a GO:0048029 (monosaccharide binding)
Timestamp Action Category Detail
2019-04-01 Added XREF Reactome:R-HSA-947991
2019-04-01 Deleted XREF reactome:R-HSA-947991
2018-12-11 Added XREF reactome:R-HSA-947991
Timestamp Action Category Detail
2015-05-19 Added SUBSET goslim_chembl
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-11 Added SUBSET goslim_ChEMBL
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