GO:0005540
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hyaluronic acid binding
Molecular Function
Definition (GO:0005540 GONUTS page)
Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
hyaluronan binding | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A0G2K2H3 | 10116 | A0A0G2K2H3_RAT | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JL46 | 10116 | A6JL46_RAT | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6KG22 | 10116 | A6KG22_RAT | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6X935 | 10090 | ITIH4_MOUSE | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:11803570 | |
NOT-qualified manual | protein | D3ZFC6 | 10116 | D3ZFC6_RAT | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZI86 | 10116 | D3ZI86_RAT | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | F7EYF5 | 10116 | F7EYF5_RAT | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | O35802 | 10116 | O35802_RAT | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q5EBC0 | 10116 | Q5EBC0_RAT | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q6QN14 | 9606 | U17L6_HUMAN | GO:0005540 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17109758 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000538 | Link domain |
InterPro | IPR026203 | Intracellular hyaluronic acid binding protein |
InterPro | IPR043210 | CD44 antigen-like |
UniProtKB-KW | KW-0373 | Hyaluronic acid |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:16336 | hyaluronic acid |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005540 based on ALL annotations
The top 100 of 509 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
hyaluronic acid binding
|
10,019.47 | 100.00 | 19,456 | 19,456 |
perineuronal net
|
9,060.36 | 37.98 | 7,699 | 8,514 |
glial cell differentiation
|
7,236.65 | 34.30 | 7,687 | 10,643 |
positive regulation of neuroblast proliferation
|
6,686.31 | 33.01 | 7,687 | 11,519 |
skeletal system development
|
3,765.47 | 23.81 | 7,661 | 20,385 |
interphotoreceptor matrix
|
9,610.51 | 15.60 | 3,055 | 3,185 |
central nervous system development
|
1,599.75 | 12.82 | 7,661 | 47,982 |
macrophage migration inhibitory factor receptor complex
|
9,545.20 | 9.78 | 1,912 | 2,007 |
photoreceptor outer segment
|
1,182.11 | 7.22 | 3,051 | 25,860 |
photoreceptor inner segment
|
1,087.18 | 5.80 | 2,153 | 19,842 |
Totals | 151368 | 7766679 |
No co-occurrence statistics for GO:0005540 based on MANUAL annotations
The top 100 of 265 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
hyaluronic acid binding
|
8,970.83 | 100.00 | 144 | 144 |
macrophage migration inhibitory factor receptor complex
|
7,935.73 | 15.65 | 23 | 26 |
receptor signaling protein tyrosine kinase inhibitor activity
|
8,472.45 | 11.72 | 17 | 18 |
negative regulation of protein tyrosine kinase activity
|
6,354.34 | 11.26 | 17 | 24 |
hyaluronoglucuronidase activity
|
4,485.41 | 10.56 | 17 | 34 |
monocyte activation
|
4,013.26 | 10.30 | 17 | 38 |
fusion of virus membrane with host plasma membrane
|
3,812.60 | 10.18 | 17 | 40 |
glycosaminoglycan catabolic process
|
2,622.24 | 10.00 | 19 | 65 |
hyalurononglucosaminidase activity
|
2,015.92 | 9.39 | 20 | 89 |
renal water absorption
|
2,675.51 | 9.24 | 17 | 57 |
Totals | 1102 | 26414 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2021-05-24 | Added | DEFINITION | Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2020-11-03 | Deleted | RELATION | is a GO:0031406 (carboxylic acid binding) |
2017-04-06 | Added | RELATION | is a GO:0031406 (carboxylic acid binding) |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2008-05-13 | Added | DEFINITION | Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2008-04-01 | Updated | RELATION | is a GO:0005539 (glycosaminoglycan binding) |
2007-08-09 | Deleted | SYNONYM | hyaluronan binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | hyaluronic acid binding |
2003-03-19 | Updated | TERM | hyaluronic acid binding activity |
2002-02-06 | Updated | TERM | hyaluronic acid binding |
2001-04-03 | Updated | TERM | hyaluronic acid binding |
2001-03-30 | Added | TERM | hyaluronic acid binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2021-05-24 | Added | DEFINITION | Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2008-05-13 | Added | DEFINITION | Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
2007-08-09 | Deleted | SYNONYM | hyaluronan binding |
2007-08-09 | Added | SYNONYM | hyaluronan binding |
2005-12-21 | Added | SYNONYM | hyaluronan binding |
2003-03-26 | Added | DEFINITION | Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-03 | Deleted | RELATION | is a GO:0031406 (carboxylic acid binding) |
2017-04-06 | Added | RELATION | is a GO:0031406 (carboxylic acid binding) |
2008-04-01 | Updated | RELATION | is a GO:0005539 (glycosaminoglycan binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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