This term is obsolete.

GO:0005547 JSON

phosphatidylinositol-3,4,5-trisphosphate binding

Molecular Function

Definition (GO:0005547 GONUTS page)

Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.

15,379 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
PIP3 binding exact

Ancestor Chart

Ancestor chart for GO:0005547
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005547

Child Term Relationship to
GO:0005547
PTEN phosphatase complex
capable_of

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5YC76 10116 A0A8I5YC76_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AFU4 10116 A0A8I6AFU4_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A9K3Y6U2 10116 A0A9K3Y6U2_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7UJ12 10116 A7UJ12_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O15537 9606 XLRS1_HUMAN GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:21196491
NOT-qualified manual protein P05943 10116 S10AA_RAT GO:0008289 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P50232 10116 SYT4_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9830048
NOT-qualified manual protein P60903 9606 S10AA_HUMAN GO:0008289 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23861394
NOT-qualified manual protein Q8VY07 3702 EPN1_ARATH GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:17277094

Cross-references

Database ID Description
InterPro IPR037858 ARAP, RhoGAP domain

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:57836 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005547 based on ALL annotations
The top 100 of 1,283 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphatidylinositol-3,4,5-trisphosphate binding
13,044.23 100.00 15,191 15,191
phosphatidylinositol-3,4-bisphosphate binding
3,546.38 14.11 3,446 12,675
phosphatidylinositol bisphosphate binding
2,422.79 11.92 3,792 20,416
lipid droplet formation
2,878.17 9.79 2,272 10,297
plus-end directed microfilament motor activity
11,461.99 8.11 1,246 1,418
regulation of filopodium assembly
4,573.90 7.14 1,249 3,562
1-phosphatidylinositol binding
1,272.38 6.33 2,323 23,815
phosphatidylinositol-3-phosphate binding
749.54 4.51 2,638 45,909
cytoskeleton-dependent intracellular transport
1,000.19 4.13 1,246 16,250
filopodium
705.38 3.54 1,409 26,056
Totals 60179 1267702
No co-occurrence statistics for GO:0005547 based on MANUAL annotations
The top 100 of 1,124 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphatidylinositol-3,4,5-trisphosphate binding
3,393.11 100.00 416 416
phosphatidylinositol-3,4-bisphosphate binding
934.54 17.15 130 472
lipid droplet formation
898.18 6.98 36 136
phosphatidylinositol-3,5-bisphosphate binding
268.99 5.29 57 719
plus-end directed microfilament motor activity
2,195.54 5.14 22 34
regulation of cell projection organization
804.55 4.69 23 97
phosphatidylinositol-3-phosphate binding
200.58 4.61 72 1,218
phosphatidylinositol-4,5-bisphosphate binding
172.34 4.32 93 1,831
phosphatidylinositol-5-phosphate binding
419.94 4.22 25 202
regulation of filopodium assembly
472.98 4.12 23 165
Totals 1959 35209

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
2021-05-24 Added DEFINITION Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
2020-11-03 Added RELATION is a GO:0043168 (anion binding)
2013-05-09 Deleted RELATION is a GO:0043168 (anion binding)
2013-03-14 Deleted RELATION is a GO:0035091 (phosphatidylinositol binding)
2013-03-14 Added RELATION is a GO:1901981 (phosphatidylinositol phosphate binding)
2012-11-02 Added RELATION is a GO:0043168 (anion binding)
2011-01-30 Added SYNONYM PIP3 binding
2010-03-19 Deleted DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol.
2010-03-19 Added DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
Timestamp Action Category Detail
2009-06-11 Updated TERM phosphatidylinositol-3,4,5-trisphosphate binding
2003-06-10 Updated TERM phosphatidylinositol-3,4,5-triphosphate binding
2003-03-19 Updated TERM phosphatidylinositol-3,4,5-triphosphate binding activity
2002-02-06 Updated TERM phosphatidylinositol-3,4,5-triphosphate binding
2001-11-13 Updated TERM phosphatidylinositol-3,4,5-triphosphate binding
2001-04-03 Updated TERM phosphatidylinositol-3,4,5 triphosphate binding
2001-03-30 Added TERM phosphatidylinositol-3,4,5 triphosphate binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
2021-05-24 Added DEFINITION Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
2011-01-30 Added SYNONYM PIP3 binding
2010-03-19 Deleted DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol.
2010-03-19 Added DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
2009-07-03 Deleted DEFINITION Interacting selectively with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol.
2009-06-11 Deleted DEFINITION Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol.
2009-06-11 Added DEFINITION Interacting selectively with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol.
2008-05-13 Added DEFINITION Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol.
2008-05-12 Deleted DEFINITION Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol.
2003-12-20 Updated DEFINITION Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol.
2003-05-28 Added DEFINITION Interacting selectively with phosphatidylinositol-3,4,5-triphosphate.
Timestamp Action Category Detail
2020-11-03 Added RELATION is a GO:0043168 (anion binding)
2013-05-09 Deleted RELATION is a GO:0043168 (anion binding)
2013-03-14 Deleted RELATION is a GO:0035091 (phosphatidylinositol binding)
2013-03-14 Added RELATION is a GO:1901981 (phosphatidylinositol phosphate binding)
2012-11-02 Added RELATION is a GO:0043168 (anion binding)
2008-04-01 Updated RELATION is a GO:0035091 (phosphatidylinositol binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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