GO:0005547
JSON
phosphatidylinositol-3,4,5-trisphosphate binding
Molecular Function
Definition (GO:0005547 GONUTS page)
Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
PIP3 binding | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005547
Child Term | Relationship to GO:0005547 |
---|---|
PTEN phosphatase complex
|
capable_of |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5YC76 | 10116 | A0A8I5YC76_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AFU4 | 10116 | A0A8I6AFU4_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A9K3Y6U2 | 10116 | A0A9K3Y6U2_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7UJ12 | 10116 | A7UJ12_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | O15537 | 9606 | XLRS1_HUMAN | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:21196491 | |
NOT-qualified manual | protein | P05943 | 10116 | S10AA_RAT | GO:0008289 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P50232 | 10116 | SYT4_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9830048 | |
NOT-qualified manual | protein | P60903 | 9606 | S10AA_HUMAN | GO:0008289 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23861394 | |
NOT-qualified manual | protein | Q8VY07 | 3702 | EPN1_ARATH | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:17277094 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR037858 | ARAP, RhoGAP domain |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:57836 | 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005547 based on ALL annotations
The top 100 of 1,274 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphatidylinositol-3,4,5-trisphosphate binding
|
13,158.20 | 100.00 | 14,815 | 14,815 |
phosphatidylinositol-3,4-bisphosphate binding
|
3,567.82 | 14.08 | 3,356 | 12,377 |
phosphatidylinositol bisphosphate binding
|
2,518.26 | 12.13 | 3,687 | 19,265 |
lipid droplet formation
|
2,879.43 | 9.65 | 2,180 | 9,962 |
plus-end directed microfilament motor activity
|
11,532.33 | 8.14 | 1,220 | 1,392 |
regulation of filopodium assembly
|
4,608.39 | 7.16 | 1,223 | 3,492 |
1-phosphatidylinositol binding
|
1,294.18 | 6.33 | 2,231 | 22,683 |
phosphatidylinositol-3-phosphate binding
|
741.07 | 4.43 | 2,546 | 45,206 |
cytoskeleton-dependent intracellular transport
|
1,014.09 | 4.15 | 1,220 | 15,830 |
filopodium
|
651.90 | 3.34 | 1,383 | 27,915 |
Totals | 58654 | 1219513 |
No co-occurrence statistics for GO:0005547 based on MANUAL annotations
The top 100 of 1,113 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphatidylinositol-3,4,5-trisphosphate binding
|
3,312.31 | 100.00 | 390 | 390 |
phosphatidylinositol-3,4-bisphosphate binding
|
957.40 | 17.84 | 124 | 429 |
lipid droplet formation
|
744.63 | 5.92 | 29 | 129 |
phosphatidylinositol-3,5-bisphosphate binding
|
277.24 | 5.62 | 57 | 681 |
plus-end directed microfilament motor activity
|
2,107.83 | 5.22 | 21 | 33 |
regulation of cell projection organization
|
875.67 | 5.07 | 23 | 87 |
phosphatidylinositol-4,5-bisphosphate binding
|
175.03 | 4.51 | 92 | 1,741 |
phosphatidylinositol-3-phosphate binding
|
187.71 | 4.42 | 65 | 1,147 |
phosphatidylinositol-5-phosphate binding
|
396.21 | 4.36 | 25 | 209 |
regulation of filopodium assembly
|
461.21 | 4.18 | 22 | 158 |
Totals | 1863 | 32990 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. |
2021-05-24 | Added | DEFINITION | Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. |
2020-11-03 | Added | RELATION | is a GO:0043168 (anion binding) |
2013-05-09 | Deleted | RELATION | is a GO:0043168 (anion binding) |
2013-03-14 | Added | RELATION | is a GO:1901981 (phosphatidylinositol phosphate binding) |
2013-03-14 | Deleted | RELATION | is a GO:0035091 (phosphatidylinositol binding) |
2012-11-02 | Added | RELATION | is a GO:0043168 (anion binding) |
2011-01-30 | Added | SYNONYM | PIP3 binding |
2010-03-19 | Added | DEFINITION | Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. |
2010-03-19 | Deleted | DEFINITION | Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-06-11 | Updated | TERM | phosphatidylinositol-3,4,5-trisphosphate binding |
2003-06-10 | Updated | TERM | phosphatidylinositol-3,4,5-triphosphate binding |
2003-03-19 | Updated | TERM | phosphatidylinositol-3,4,5-triphosphate binding activity |
2002-02-06 | Updated | TERM | phosphatidylinositol-3,4,5-triphosphate binding |
2001-11-13 | Updated | TERM | phosphatidylinositol-3,4,5-triphosphate binding |
2001-04-03 | Updated | TERM | phosphatidylinositol-3,4,5 triphosphate binding |
2001-03-30 | Added | TERM | phosphatidylinositol-3,4,5 triphosphate binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. |
2021-05-24 | Added | DEFINITION | Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. |
2011-01-30 | Added | SYNONYM | PIP3 binding |
2010-03-19 | Added | DEFINITION | Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. |
2010-03-19 | Deleted | DEFINITION | Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol. |
2009-06-11 | Deleted | DEFINITION | Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol. |
2009-06-11 | Added | DEFINITION | Interacting selectively with phosphatidylinositol-3,4,5-trisphosphate, the triply phosphorylated derivative of phosphatidylinositol. |
2008-05-13 | Added | DEFINITION | Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol. |
2003-12-20 | Updated | DEFINITION | Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol. |
2003-05-28 | Added | DEFINITION | Interacting selectively with phosphatidylinositol-3,4,5-triphosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-03 | Added | RELATION | is a GO:0043168 (anion binding) |
2013-05-09 | Deleted | RELATION | is a GO:0043168 (anion binding) |
2013-03-14 | Added | RELATION | is a GO:1901981 (phosphatidylinositol phosphate binding) |
2013-03-14 | Deleted | RELATION | is a GO:0035091 (phosphatidylinositol binding) |
2012-11-02 | Added | RELATION | is a GO:0043168 (anion binding) |
2008-04-01 | Updated | RELATION | is a GO:0035091 (phosphatidylinositol binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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