A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP.
GO:0005684
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U2-type spliceosomal complex
Cellular Component
Definition (GO:0005684 GONUTS page)
Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. PMID:11343900
Comments
A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
major (U2-type) spliceosomal complex | exact |
GT-AG spliceosome | narrow |
major spliceosomal complex | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005684
Child Term | Relationship to GO:0005684 |
---|---|
U2-type post-mRNA release spliceosomal complex
|
is_a |
U2-type catalytic step 2 spliceosome
|
is_a |
U2-type catalytic step 1 spliceosome
|
is_a |
commitment complex
|
is_a |
U2-type precatalytic spliceosome
|
is_a |
U2-type prespliceosome
|
is_a |
U2-type post-spliceosomal complex
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0005684 | U2-type spliceosomal complex | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JW23 | 10116 | A0A0G2JW23_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K8T1 | 10116 | A0A0G2K8T1_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GR71 | 10090 | A0A1B0GR71_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1B0GRK6 | 10090 | A0A1B0GRK6_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y8H4 | 10116 | A0A8I5Y8H4_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A0E5 | 10116 | A0A8I6A0E5_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005684 based on ALL annotations
The top 100 of 378 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
U2-type spliceosomal complex
|
7,083.53 | 100.00 | 27,520 | 27,520 |
snoRNA splicing
|
6,834.65 | 15.48 | 4,284 | 4,440 |
post-mRNA release spliceosomal complex
|
1,726.12 | 15.21 | 7,925 | 32,522 |
RES complex
|
7,009.98 | 14.87 | 4,098 | 4,141 |
U2 snRNP
|
645.83 | 6.84 | 5,908 | 64,800 |
mRNA splicing, via spliceosome
|
412.60 | 5.67 | 18,868 | 323,929 |
U2-type precatalytic spliceosome
|
2,311.38 | 5.31 | 1,640 | 5,026 |
RNA splicing
|
257.67 | 3.53 | 15,114 | 415,501 |
spliceosomal complex
|
224.43 | 2.95 | 8,182 | 258,238 |
U12-type spliceosomal complex
|
432.28 | 2.57 | 1,167 | 19,123 |
Totals | 146157 | 24584767 |
No co-occurrence statistics for GO:0005684 based on MANUAL annotations
The top 100 of 156 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
U2-type spliceosomal complex
|
1,231.46 | 100.00 | 1,049 | 1,049 |
U2 snRNP
|
221.03 | 13.71 | 385 | 2,145 |
post-mRNA release spliceosomal complex
|
283.11 | 11.74 | 203 | 883 |
snoRNA splicing
|
1,201.90 | 11.60 | 122 | 125 |
U2-type precatalytic spliceosome
|
450.53 | 9.55 | 120 | 328 |
RES complex
|
1,205.80 | 8.94 | 94 | 96 |
precatalytic spliceosome
|
115.36 | 7.06 | 234 | 2,498 |
mRNA splicing, via spliceosome
|
86.76 | 6.73 | 630 | 8,942 |
U12-type spliceosomal complex
|
172.17 | 6.19 | 105 | 751 |
methylosome
|
594.86 | 5.14 | 57 | 118 |
Totals | 4966 | 418900 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2009-08-28 | Deleted | DEFINITION | A spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. |
2009-08-28 | Added | DEFINITION | Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. |
2009-08-03 | Added | SYNONYM | major (U2-type) spliceosomal complex |
2009-08-03 | Updated | TERM | U2-type spliceosomal complex |
2009-08-03 | Added | SYNONYM | major spliceosomal complex |
2009-08-03 | Added | DEFINITION | A spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. |
2009-08-03 | Deleted | SYNONYM | GT-AG spliceosome |
2009-08-03 | Deleted | SYNONYM | major spliceosome |
2009-08-03 | Deleted | SYNONYM | major (U2-dependent) spliceosome |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-08-03 | Updated | TERM | U2-type spliceosomal complex |
2007-01-15 | Updated | TERM | U2-dependent spliceosome |
2002-06-23 | Updated | TERM | major (U2-dependent) spliceosome |
2002-02-06 | Updated | TERM | GT-AG spliceosome |
2001-04-03 | Updated | TERM | GT-AG spliceosome |
2001-03-30 | Added | TERM | GT-AG spliceosome |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-08-28 | Deleted | DEFINITION | A spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. |
2009-08-28 | Added | DEFINITION | Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. |
2009-08-03 | Added | SYNONYM | major (U2-type) spliceosomal complex |
2009-08-03 | Added | SYNONYM | major spliceosomal complex |
2009-08-03 | Added | DEFINITION | A spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. |
2009-08-03 | Deleted | SYNONYM | GT-AG spliceosome |
2009-08-03 | Deleted | SYNONYM | major spliceosome |
2009-08-03 | Deleted | SYNONYM | major (U2-dependent) spliceosome |
2009-08-03 | Added | SYNONYM | GT-AG spliceosome |
2009-08-03 | Deleted | DEFINITION | The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons. |
2008-05-13 | Added | DEFINITION | The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons. |
2008-05-12 | Deleted | DEFINITION | The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons. |
2007-08-09 | Added | SYNONYM | GT-AG spliceosome |
2007-08-09 | Deleted | SYNONYM | major (U2-dependent) spliceosome |
2007-08-09 | Deleted | SYNONYM | major spliceosome |
2007-08-09 | Deleted | SYNONYM | GT-AG spliceosome |
2007-08-09 | Added | SYNONYM | major spliceosome |
2007-08-09 | Added | SYNONYM | major (U2-dependent) spliceosome |
2007-01-15 | Added | SYNONYM | major (U2-dependent) spliceosome |
2004-04-19 | Added | SYNONYM | major spliceosome |
2004-04-19 | Added | SYNONYM | GT-AG spliceosome |
2004-04-16 | Deleted | SYNONYM | major spliceosome |
2004-04-16 | Deleted | SYNONYM | GT-AG spliceosome |
2002-11-27 | Added | DEFINITION | The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons. |
2002-06-23 | Added | SYNONYM | GT-AG spliceosome |
2002-04-17 | Added | SYNONYM | major spliceosome |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0005681 (spliceosomal complex) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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