This term is obsolete.
A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP.

GO:0005684 JSON

U2-type spliceosomal complex

Cellular Component

Definition (GO:0005684 GONUTS page)

Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. PMID:11343900

Comments

A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP.

137,535 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
major (U2-type) spliceosomal complex exact
GT-AG spliceosome narrow
major spliceosomal complex exact

Ancestor Chart

Ancestor chart for GO:0005684
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005684

Child Term Relationship to
GO:0005684
U2-type post-mRNA release spliceosomal complex
is_a
U2-type catalytic step 2 spliceosome
is_a
U2-type catalytic step 1 spliceosome
is_a
commitment complex
is_a
U2-type precatalytic spliceosome
is_a
U2-type prespliceosome
is_a
U2-type post-spliceosomal complex
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005684 U2-type spliceosomal complex Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2JW23 10116 A0A0G2JW23_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K8T1 10116 A0A0G2K8T1_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1B0GR71 10090 A0A1B0GR71_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1B0GRK6 10090 A0A1B0GRK6_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5Y8H4 10116 A0A8I5Y8H4_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A0E5 10116 A0A8I6A0E5_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005684 based on ALL annotations
The top 100 of 378 co-occurring terms
Co-occurring Term PR S% #Together #Compared
U2-type spliceosomal complex
7,083.53 100.00 27,520 27,520
snoRNA splicing
6,834.65 15.48 4,284 4,440
post-mRNA release spliceosomal complex
1,726.12 15.21 7,925 32,522
RES complex
7,009.98 14.87 4,098 4,141
U2 snRNP
645.83 6.84 5,908 64,800
mRNA splicing, via spliceosome
412.60 5.67 18,868 323,929
U2-type precatalytic spliceosome
2,311.38 5.31 1,640 5,026
RNA splicing
257.67 3.53 15,114 415,501
spliceosomal complex
224.43 2.95 8,182 258,238
U12-type spliceosomal complex
432.28 2.57 1,167 19,123
Totals 146157 24584767
No co-occurrence statistics for GO:0005684 based on MANUAL annotations
The top 100 of 156 co-occurring terms
Co-occurring Term PR S% #Together #Compared
U2-type spliceosomal complex
1,231.46 100.00 1,049 1,049
U2 snRNP
221.03 13.71 385 2,145
post-mRNA release spliceosomal complex
283.11 11.74 203 883
snoRNA splicing
1,201.90 11.60 122 125
U2-type precatalytic spliceosome
450.53 9.55 120 328
RES complex
1,205.80 8.94 94 96
precatalytic spliceosome
115.36 7.06 234 2,498
mRNA splicing, via spliceosome
86.76 6.73 630 8,942
U12-type spliceosomal complex
172.17 6.19 105 751
methylosome
594.86 5.14 57 118
Totals 4966 418900

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2009-08-28 Deleted DEFINITION A spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
2009-08-28 Added DEFINITION Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
2009-08-03 Added SYNONYM major (U2-type) spliceosomal complex
2009-08-03 Updated TERM U2-type spliceosomal complex
2009-08-03 Added SYNONYM major spliceosomal complex
2009-08-03 Added DEFINITION A spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
2009-08-03 Deleted SYNONYM GT-AG spliceosome
2009-08-03 Deleted SYNONYM major spliceosome
2009-08-03 Deleted SYNONYM major (U2-dependent) spliceosome
Timestamp Action Category Detail
2009-08-03 Updated TERM U2-type spliceosomal complex
2007-01-15 Updated TERM U2-dependent spliceosome
2002-06-23 Updated TERM major (U2-dependent) spliceosome
2002-02-06 Updated TERM GT-AG spliceosome
2001-04-03 Updated TERM GT-AG spliceosome
2001-03-30 Added TERM GT-AG spliceosome
Timestamp Action Category Detail
2009-08-28 Deleted DEFINITION A spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
2009-08-28 Added DEFINITION Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
2009-08-03 Added SYNONYM major (U2-type) spliceosomal complex
2009-08-03 Added SYNONYM major spliceosomal complex
2009-08-03 Added DEFINITION A spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
2009-08-03 Deleted SYNONYM GT-AG spliceosome
2009-08-03 Deleted SYNONYM major spliceosome
2009-08-03 Deleted SYNONYM major (U2-dependent) spliceosome
2009-08-03 Added SYNONYM GT-AG spliceosome
2009-08-03 Deleted DEFINITION The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons.
2008-05-13 Added DEFINITION The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons.
2008-05-12 Deleted DEFINITION The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons.
2007-08-09 Added SYNONYM GT-AG spliceosome
2007-08-09 Deleted SYNONYM major (U2-dependent) spliceosome
2007-08-09 Deleted SYNONYM major spliceosome
2007-08-09 Deleted SYNONYM GT-AG spliceosome
2007-08-09 Added SYNONYM major spliceosome
2007-08-09 Added SYNONYM major (U2-dependent) spliceosome
2007-01-15 Added SYNONYM major (U2-dependent) spliceosome
2004-04-19 Added SYNONYM major spliceosome
2004-04-19 Added SYNONYM GT-AG spliceosome
2004-04-16 Deleted SYNONYM major spliceosome
2004-04-16 Deleted SYNONYM GT-AG spliceosome
2002-11-27 Added DEFINITION The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons.
2002-06-23 Added SYNONYM GT-AG spliceosome
2002-04-17 Added SYNONYM major spliceosome
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005681 (spliceosomal complex)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
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