This term is obsolete.

GO:0006084 JSON

acetyl-CoA metabolic process

Biological Process

Definition (GO:0006084 GONUTS page)

The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.

352,616 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
acetyl coenzyme A metabolic process exact
acetyl-CoA metabolism exact
acetyl coenzyme A metabolism exact

Ancestor Chart

Ancestor chart for GO:0006084
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006084

Child Term Relationship to
GO:0006084
acetyl-CoA catabolic process
is_a
butyryl-CoA biosynthetic process from acetyl-CoA
is_a
L-lysine catabolic process to acetyl-CoA
is_a
L-tryptophan catabolic process to acetyl-CoA
is_a
acetyl-CoA biosynthetic process
is_a
isopentenyl diphosphate biosynthetic process, mevalonate pathway
is_a
L-threonine catabolic process to acetyl-CoA
is_a

Cross-references

Database ID Description
InterPro IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha
InterPro IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit
InterPro IPR006472 Citrate lyase, alpha subunit
InterPro IPR006475 Citrate lyase, beta subunit, bacteria
InterPro IPR013746 Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain
InterPro IPR017821 Succinate CoA transferase
InterPro IPR023427 Acetyl-CoA decarbonylase/synthase complex, gamma subunit, archaea
InterPro IPR023432 Acetyl-CoA decarbonylase/synthase complex subunit beta, archaeal

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input_or_output CHEBI CHEBI:57288 acetyl-CoA(4-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006084 based on ALL annotations
The top 100 of 392 co-occurring terms
Co-occurring Term PR S% #Together #Compared
acetyl-CoA metabolic process
5,818.67 100.00 34,055 34,055
hydroxymethylglutaryl-CoA synthase activity
5,436.54 40.07 14,042 15,029
farnesyl diphosphate biosynthetic process, mevalonate pathway
4,485.49 25.57 9,424 12,225
ATP-independent citrate lyase complex
5,818.67 20.10 6,844 6,844
acetyl-CoA hydrolase activity
4,145.73 20.01 7,412 10,403
citrate (pro-3S)-lyase activity
4,903.02 16.42 5,767 6,844
citrate CoA-transferase activity
5,817.49 14.44 4,916 4,917
acetate CoA-transferase activity
1,545.04 14.19 7,950 29,940
anaerobic carbon-monoxide dehydrogenase activity
2,002.38 9.86 4,133 12,010
acetate metabolic process
680.38 8.45 7,951 67,998
Totals 192588 102418739
No co-occurrence statistics for GO:0006084 based on MANUAL annotations
The top 100 of 168 co-occurring terms
Co-occurring Term PR S% #Together #Compared
acetyl-CoA metabolic process
5,856.98 100.00 241 241
hydroxymethylglutaryl-CoA synthase activity
5,738.06 78.78 193 197
farnesyl diphosphate biosynthetic process, mevalonate pathway
4,011.93 57.19 187 273
acetyl-CoA hydrolase activity
1,987.19 6.83 19 56
intracellular aspartate homeostasis
5,856.98 3.32 8 8
lactic acid secretion
5,206.21 3.31 8 9
regulation of cardiac muscle hypertrophy in response to stress
4,685.59 3.29 8 10
biotin binding
1,033.59 3.18 9 51
intracellular glutamate homeostasis
2,342.79 3.16 8 20
ergosterol biosynthetic process
302.95 3.15 18 348
Totals 992 15230

Change Log

Timestamp Action Category Detail
2020-05-09 Deleted RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2020-05-08 Added RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2012-11-02 Added RELATION is a GO:0006637 (acyl-CoA metabolic process)
2012-11-02 Deleted RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2008-05-13 Added DEFINITION The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2008-04-01 Updated RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2007-08-09 Deleted SYNONYM acetyl-CoA metabolism
2007-08-09 Deleted SYNONYM acetyl coenzyme A metabolic process
2007-08-09 Added SYNONYM acetyl-CoA metabolism
Timestamp Action Category Detail
2007-01-15 Updated TERM acetyl-CoA metabolic process
2002-02-06 Updated TERM acetyl-CoA metabolism
2001-04-03 Updated TERM acetyl-CoA metabolism
2001-03-30 Added TERM acetyl-CoA metabolism
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2007-08-09 Deleted SYNONYM acetyl-CoA metabolism
2007-08-09 Deleted SYNONYM acetyl coenzyme A metabolic process
2007-08-09 Added SYNONYM acetyl-CoA metabolism
2007-08-09 Added SYNONYM acetyl coenzyme A metabolism
2007-08-09 Added SYNONYM acetyl coenzyme A metabolic process
2007-08-09 Deleted SYNONYM acetyl coenzyme A metabolism
2007-01-29 Added SYNONYM acetyl-CoA metabolism
2007-01-15 Added SYNONYM acetyl coenzyme A metabolic process
2006-05-04 Updated DEFINITION The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2005-07-09 Added SYNONYM acetyl coenzyme A metabolism
2005-01-21 Updated DEFINITION The chemical reactions involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2004-03-13 Updated DEFINITION The chemical reactions and physical changes involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2003-10-18 Updated DEFINITION The chemical reactions and physical changes involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (eg. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2003-04-24 Updated DEFINITION The chemical reactions and physical changes involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e. g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2003-03-26 Updated DEFINITION The chemical reactions and physical changes involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2002-11-27 Updated DEFINITION The chemical reactions and physical changes involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism); further metabolized by the tricarboxylic acid cycle; a key intermediate in lipid and terpenoid biosynthesis.
2001-08-06 Added DEFINITION Metabolism of acetyl-coenzyme A: a derivative of coenzyme A in which the sulfhydryl group is acetylated; a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism); further metabolised by the tricarboxylic acid cycle; a key intermediate in lipid and terpenoid biosynthesis.
Timestamp Action Category Detail
2020-05-09 Deleted RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2020-05-08 Added RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2012-11-02 Added RELATION is a GO:0006637 (acyl-CoA metabolic process)
2012-11-02 Deleted RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2008-04-01 Updated RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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