GO:0006415
JSON
translational termination
Biological Process
Definition (GO:0006415 GONUTS page)
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
Secondary IDs
GO:0006443, GO:0006456
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
translation termination | exact |
protein synthesis termination | broad |
translational complex disassembly | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006415
Child Term | Relationship to GO:0006415 |
---|---|
translation termination factor activity
|
part_of |
negative regulation of translational termination
|
negatively_regulates |
mitochondrial translational termination
|
is_a |
cytoplasmic translational termination
|
is_a |
regulation of translational termination
|
regulates |
positive regulation of translational termination
|
positively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0006415 | translational termination | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000352 | Peptide chain release factor class I |
InterPro | IPR003285 | Eukaryotic peptide chain release factor GTP-binding subunit |
InterPro | IPR004373 | Peptide chain release factor 1 |
InterPro | IPR004374 | Peptide chain release factor 2 |
InterPro | IPR004403 | Peptide chain release factor eRF1/aRF1 |
InterPro | IPR004548 | Peptide chain release factor 3 |
InterPro | IPR005139 | Peptide chain release factor |
InterPro | IPR020918 | Peptide chain release factor aRF1 |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0016148 | obsolete protein-synthesizing GTPase activity, termination | consider GO:0006415 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006415 based on ALL annotations
The top 100 of 811 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
translational termination
|
938.48 | 100.00 | 207,717 | 207,717 |
translation release factor activity, codon specific
|
938.48 | 50.36 | 104,615 | 104,615 |
translation release factor activity
|
938.40 | 27.21 | 56,530 | 56,535 |
translation release factor activity, codon nonspecific
|
930.23 | 14.37 | 29,878 | 30,143 |
regulation of translational termination
|
782.70 | 11.21 | 23,815 | 28,555 |
ribosomal large subunit binding
|
205.20 | 11.09 | 38,130 | 174,390 |
aminoacyl-tRNA hydrolase activity
|
247.43 | 8.17 | 21,999 | 83,440 |
rescue of stalled ribosome
|
289.33 | 7.56 | 18,908 | 61,330 |
cytoplasmic translational termination
|
902.10 | 7.03 | 14,653 | 15,244 |
ribosome binding
|
36.18 | 2.79 | 19,037 | 493,807 |
Totals | 1018901 | 84469563 |
No co-occurrence statistics for GO:0006415 based on MANUAL annotations
The top 100 of 153 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
translational termination
|
3,777.19 | 100.00 | 342 | 342 |
protein-glutamine N-methyltransferase activity
|
3,222.74 | 25.98 | 93 | 109 |
ribosomal small subunit binding
|
886.77 | 18.44 | 158 | 673 |
iron ion binding
|
589.14 | 13.20 | 158 | 1,013 |
translation release factor activity, codon nonspecific
|
1,405.47 | 8.08 | 32 | 86 |
translation release factor activity
|
764.43 | 7.14 | 34 | 168 |
translational initiation
|
212.97 | 5.29 | 159 | 2,820 |
translation release factor complex
|
240.37 | 3.23 | 21 | 330 |
ATP binding
|
92.27 | 2.38 | 159 | 6,509 |
regulation of translational termination
|
414.57 | 2.17 | 9 | 82 |
Totals | 1492 | 170013 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2022-01-12 | Added | RELATION | is a GO:0032984 (protein-containing complex disassembly) |
2022-01-12 | Deleted | RELATION | is a GO:0043624 (cellular protein complex disassembly) |
2020-02-28 | Deleted | XREF | MIPS_funcat:12.04.03 |
2019-05-04 | Added | XREF | MIPS_funcat:12.04.03 |
2017-05-01 | Added | RELATION | has part GO:0006412 (translation) |
2008-05-13 | Added | DEFINITION | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). |
2008-05-12 | Deleted | DEFINITION | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). |
2008-04-01 | Updated | RELATION | is a GO:0043624 (cellular protein complex disassembly) |
2008-04-01 | Updated | RELATION | part of GO:0006412 (translation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-08-05 | Updated | TERM | translational termination |
2002-02-06 | Updated | TERM | protein synthesis termination |
2001-04-03 | Updated | TERM | protein synthesis termination |
2001-03-30 | Added | TERM | protein synthesis termination |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). |
2008-05-12 | Deleted | DEFINITION | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). |
2007-08-09 | Added | SYNONYM | translational complex disassembly |
2007-08-09 | Deleted | SYNONYM | protein synthesis termination |
2007-08-09 | Deleted | SYNONYM | translation termination |
2007-08-09 | Added | SYNONYM | translation termination |
2007-08-09 | Added | SYNONYM | protein synthesis termination |
2007-08-09 | Deleted | SYNONYM | translational complex disassembly |
2007-07-11 | Deleted | SYNONYM | protein-synthesizing GTPase activity, termination |
2007-01-15 | Added | SYNONYM | translational complex disassembly |
2005-08-19 | Added | SYNONYM | translation termination |
2005-08-10 | Added | SYNONYM | protein-synthesizing GTPase activity, termination |
2004-08-29 | Updated | DEFINITION | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). |
2004-04-19 | Added | SYNONYM | protein synthesis termination |
2004-04-16 | Deleted | SYNONYM | protein synthesis termination |
2002-11-27 | Added | DEFINITION | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA). |
2002-08-05 | Added | SYNONYM | protein synthesis termination |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-01-12 | Added | RELATION | is a GO:0032984 (protein-containing complex disassembly) |
2022-01-12 | Deleted | RELATION | is a GO:0043624 (cellular protein complex disassembly) |
2017-05-01 | Added | RELATION | has part GO:0006412 (translation) |
2008-04-01 | Updated | RELATION | is a GO:0043624 (cellular protein complex disassembly) |
2008-04-01 | Updated | RELATION | part of GO:0006412 (translation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:12.04.03 |
2019-05-04 | Added | XREF | MIPS_funcat:12.04.03 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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