This term is obsolete.

GO:0006423 JSON

cysteinyl-tRNA aminoacylation

Biological Process

Definition (GO:0006423 GONUTS page)

The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.

65,344 annotations

Ancestor Chart

Ancestor chart for GO:0006423
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006423

Child Term Relationship to
GO:0006423
mitochondrial cysteinyl-tRNA aminoacylation
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0006423 cysteinyl-tRNA aminoacylation Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein O14133 284812 ATE1_SCHPO GO:0006399 1 NOT-qualified manual annotation exists with evidence code ECO:0000303 from this reference: GO_REF:0000051

Cross-references

Database ID Description
InterPro IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR
InterPro IPR015803 Cysteine-tRNA ligase

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006423 based on ALL annotations
The top 100 of 250 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cysteinyl-tRNA aminoacylation
3,046.01 100.00 65,054 65,054
cysteine-tRNA ligase activity
3,037.28 99.71 65,054 65,241
cysteine-glucosaminylinositol ligase activity
3,036.24 6.69 4,354 4,368
mycothiol biosynthetic process
823.92 5.66 4,346 16,067
aminoacyl-tRNA ligase activity
133.68 4.36 56,060 1,277,409
tRNA aminoacylation for protein translation
61.24 1.75 7,776 386,749
zinc ion binding
18.84 0.62 47,097 7,614,055
translation
14.24 0.47 53,900 11,526,905
cytosol
11.46 0.38 52,640 13,989,509
ATP binding
10.42 0.34 65,054 19,024,482
Totals 555309 131961776
No co-occurrence statistics for GO:0006423 based on MANUAL annotations
The top 26 of 26 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cysteinyl-tRNA aminoacylation
5,077.46 100.00 278 278
cysteine-tRNA ligase activity
5,077.46 100.00 278 278
ATP binding
202.39 3.98 273 6,849
tRNA binding
27.30 0.49 14 2,604
cysteine-glucosaminylinositol ligase activity
5,077.46 0.36 1 1
aminoacyl-tRNA ligase activity
846.24 0.35 1 6
mycothiol biosynthetic process
634.68 0.35 1 8
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
220.76 0.33 1 23
spore germination
99.56 0.30 1 51
ligase activity
69.55 0.29 1 73
Totals 1202 636359

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2022-11-08 Added DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
2022-11-08 Deleted DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
2018-02-10 Added DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
2018-02-10 Deleted DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
2008-05-13 Added DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
2008-05-12 Deleted DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
2008-04-01 Updated RELATION is a GO:0006418 (tRNA aminoacylation for protein translation)
2004-06-03 Added DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
2002-02-06 Updated TERM cysteinyl-tRNA aminoacylation
Timestamp Action Category Detail
2002-02-06 Updated TERM cysteinyl-tRNA aminoacylation
2001-04-03 Updated TERM cysteinyl-tRNA aminoacylation
2001-03-30 Added TERM cysteinyl-tRNA aminoacylation
Timestamp Action Category Detail
2022-11-08 Added DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
2022-11-08 Deleted DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
2018-02-10 Added DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
2018-02-10 Deleted DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
2008-05-13 Added DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
2008-05-12 Deleted DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
2004-06-03 Added DEFINITION The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0006418 (tRNA aminoacylation for protein translation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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