GO:0006446
JSON
regulation of translational initiation
Biological Process
Definition (GO:0006446 GONUTS page)
Any process that modulates the frequency, rate or extent of translational initiation.
Ancestor Chart
Ancestor chart for GO:0006446
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006446
Child Term | Relationship to GO:0006446 |
---|---|
regulation of eIF2 alpha phosphorylation by heme
|
is_a |
regulation of cytoplasmic translational initiation
|
is_a |
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
|
is_a |
regulation of translational initiation in response to stress
|
is_a |
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
|
is_a |
regulation of translational initiation by iron
|
is_a |
regulation of eIF2 alpha phosphorylation by dsRNA
|
is_a |
negative regulation of translational initiation
|
is_a |
positive regulation of translational initiation
|
is_a |
regulation of mitochondrial translational initiation
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5Y7T8 | 10116 | A0A8I5Y7T8_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5YBE4 | 10116 | A0A8I5YBE4_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN4 | 10116 | A6HXN4_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN5 | 10116 | A6HXN5_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN7 | 10116 | A6HXN7_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JXC6 | 10116 | A6JXC6_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZJ50 | 10116 | D3ZJ50_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A417 | 10116 | D4A417_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q3KR54 | 10116 | ADAD1_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR016020 | Translation initiation factor 3, subunit 12, N-terminal, eukaryotic |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006446 based on ALL annotations
The top 100 of 797 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
regulation of translational initiation
|
4,613.61 | 100.00 | 42,253 | 42,253 |
GCN2-mediated signaling
|
4,144.30 | 13.14 | 5,634 | 6,272 |
translation activator activity
|
2,835.56 | 10.23 | 4,620 | 7,517 |
guanyl ribonucleotide binding
|
1,834.27 | 9.05 | 4,433 | 11,150 |
cytoplasmic translational initiation
|
349.93 | 4.28 | 3,773 | 49,744 |
eukaryotic 48S preinitiation complex
|
344.32 | 4.16 | 3,633 | 48,679 |
formation of cytoplasmic translation initiation complex
|
336.49 | 4.13 | 3,669 | 50,305 |
eukaryotic 43S preinitiation complex
|
350.41 | 4.04 | 3,365 | 44,305 |
eukaryotic translation initiation factor 3 complex
|
291.41 | 3.94 | 3,996 | 63,264 |
positive regulation of translation
|
248.12 | 3.72 | 4,559 | 84,770 |
Totals | 127610 | 4006123 |
No co-occurrence statistics for GO:0006446 based on MANUAL annotations
The top 100 of 490 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
regulation of translational initiation
|
2,387.80 | 100.00 | 541 | 541 |
eukaryotic translation initiation factor 2alpha kinase activity
|
1,100.26 | 19.97 | 141 | 306 |
GCN2-mediated signaling
|
1,946.58 | 13.44 | 75 | 92 |
translation activator activity
|
1,109.09 | 13.30 | 85 | 183 |
eukaryotic translation initiation factor 3 complex
|
133.21 | 4.00 | 67 | 1,201 |
translation factor activity, RNA binding
|
249.89 | 2.59 | 18 | 172 |
translation initiation factor activity
|
66.23 | 2.53 | 119 | 4,290 |
negative regulation of translation
|
67.60 | 2.30 | 59 | 2,084 |
regulation of cytoplasmic translational initiation in response to stress
|
1,250.75 | 2.00 | 11 | 21 |
eukaryotic translation initiation factor 4F complex
|
76.04 | 1.92 | 25 | 785 |
Totals | 1735 | 34372 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2009-04-06 | Deleted | RELATION | is a GO:0050794 (regulation of cellular process) |
2009-04-03 | Deleted | RELATION | is a GO:0051128 (regulation of cellular component organization) |
2009-04-03 | Added | RELATION | is a GO:0050794 (regulation of cellular process) |
2008-05-13 | Added | DEFINITION | Any process that modulates the frequency, rate or extent of translational initiation. |
2008-05-12 | Deleted | DEFINITION | Any process that modulates the frequency, rate or extent of translational initiation. |
2008-04-01 | Updated | RELATION | part of GO:0006413 (translational initiation) |
2008-04-01 | Added | RELATION | regulates GO:0006413 (translational initiation) |
2008-04-01 | Deleted | RELATION | part of GO:0006413 (translational initiation) |
2008-04-01 | Updated | RELATION | is a GO:0051128 (regulation of cellular component organization) |
2008-04-01 | Updated | RELATION | is a GO:0006417 (regulation of translation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-07-17 | Updated | TERM | regulation of translational initiation |
2002-02-06 | Updated | TERM | translational regulation, initiation |
2001-04-03 | Updated | TERM | translational regulation, initiation |
2001-03-30 | Added | TERM | translational regulation, initiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Any process that modulates the frequency, rate or extent of translational initiation. |
2008-05-12 | Deleted | DEFINITION | Any process that modulates the frequency, rate or extent of translational initiation. |
2002-11-27 | Added | DEFINITION | Any process that modulates the frequency, rate or extent of translational initiation. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-04-06 | Deleted | RELATION | is a GO:0050794 (regulation of cellular process) |
2009-04-03 | Deleted | RELATION | is a GO:0051128 (regulation of cellular component organization) |
2009-04-03 | Added | RELATION | is a GO:0050794 (regulation of cellular process) |
2008-04-01 | Updated | RELATION | part of GO:0006413 (translational initiation) |
2008-04-01 | Added | RELATION | regulates GO:0006413 (translational initiation) |
2008-04-01 | Deleted | RELATION | part of GO:0006413 (translational initiation) |
2008-04-01 | Updated | RELATION | is a GO:0051128 (regulation of cellular component organization) |
2008-04-01 | Updated | RELATION | is a GO:0006417 (regulation of translation) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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