This term is obsolete.

GO:0006446 JSON

regulation of translational initiation

Biological Process

Definition (GO:0006446 GONUTS page)

Any process that modulates the frequency, rate or extent of translational initiation.

261,623 annotations

Ancestor Chart

Ancestor chart for GO:0006446
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006446

Child Term Relationship to
GO:0006446
regulation of cytoplasmic translational initiation
is_a
regulation of mitochondrial translational initiation
is_a
regulation of eIF2 alpha phosphorylation by heme
is_a
positive regulation of translational initiation
is_a
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
is_a
negative regulation of translational initiation
is_a
regulation of translational initiation by tRNA modification
is_a
regulation of eIF2 alpha phosphorylation by dsRNA
is_a
regulation of translational initiation in response to stress
is_a
regulation of translational initiation by iron
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5Y7T8 10116 A0A8I5Y7T8_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5YBE4 10116 A0A8I5YBE4_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HXN4 10116 A6HXN4_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HXN5 10116 A6HXN5_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HXN7 10116 A6HXN7_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JXC6 10116 A6JXC6_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZJ50 10116 D3ZJ50_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A417 10116 D4A417_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P9WNV7 83332 DNAJ2_MYCTU GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487
NOT-qualified manual protein Q3KR54 10116 ADAD1_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR016020 Translation initiation factor 3, subunit 12, N-terminal, eukaryotic

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006446 based on ALL annotations
The top 100 of 763 co-occurring terms
Co-occurring Term PR S% #Together #Compared
regulation of translational initiation
4,754.42 100.00 41,678 41,678
GCN2-mediated signaling
4,278.24 13.57 5,741 6,380
translation activator activity
2,919.01 10.66 4,760 7,753
guanyl ribonucleotide binding
1,901.60 9.37 4,542 11,356
cytoplasmic translational initiation
356.90 4.32 3,852 51,314
eukaryotic 48S preinitiation complex
351.10 4.21 3,711 50,252
formation of cytoplasmic translation initiation complex
343.01 4.17 3,748 51,950
eukaryotic 43S preinitiation complex
358.41 4.10 3,444 45,686
eukaryotic translation initiation factor 3 complex
297.65 3.99 4,140 66,128
positive regulation of translation
258.14 3.80 4,695 86,472
Totals 171205 35100632
No co-occurrence statistics for GO:0006446 based on MANUAL annotations
The top 100 of 490 co-occurring terms
Co-occurring Term PR S% #Together #Compared
regulation of translational initiation
2,454.84 100.00 575 575
eukaryotic translation initiation factor 2alpha kinase activity
1,190.96 20.11 147 303
translation activator activity
1,227.42 15.07 102 204
GCN2-mediated signaling
2,029.00 13.68 81 98
negative regulation of translation
132.12 4.40 112 2,081
eukaryotic translation initiation factor 3 complex
128.30 3.74 67 1,282
translation factor activity, RNA binding
233.79 2.41 18 189
translation initiation factor activity
62.62 2.32 119 4,665
regulation of cytoplasmic translational initiation in response to stress
1,402.77 2.05 12 21
eukaryotic translation initiation factor 4F complex
72.20 1.79 25 850
Totals 1872 36251

Change Log

Timestamp Action Category Detail
2009-04-06 Deleted RELATION is a GO:0050794 (regulation of cellular process)
2009-04-03 Added RELATION is a GO:0050794 (regulation of cellular process)
2009-04-03 Deleted RELATION is a GO:0051128 (regulation of cellular component organization)
2008-05-13 Added DEFINITION Any process that modulates the frequency, rate or extent of translational initiation.
2008-05-12 Deleted DEFINITION Any process that modulates the frequency, rate or extent of translational initiation.
2008-04-01 Updated RELATION part of GO:0006413 (translational initiation)
2008-04-01 Added RELATION regulates GO:0006413 (translational initiation)
2008-04-01 Deleted RELATION part of GO:0006413 (translational initiation)
2008-04-01 Updated RELATION is a GO:0006417 (regulation of translation)
2008-04-01 Updated RELATION is a GO:0051128 (regulation of cellular component organization)
Timestamp Action Category Detail
2002-07-17 Updated TERM regulation of translational initiation
2002-02-06 Updated TERM translational regulation, initiation
2001-04-03 Updated TERM translational regulation, initiation
2001-03-30 Added TERM translational regulation, initiation
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that modulates the frequency, rate or extent of translational initiation.
2008-05-12 Deleted DEFINITION Any process that modulates the frequency, rate or extent of translational initiation.
2002-11-27 Added DEFINITION Any process that modulates the frequency, rate or extent of translational initiation.
Timestamp Action Category Detail
2009-04-06 Deleted RELATION is a GO:0050794 (regulation of cellular process)
2009-04-03 Added RELATION is a GO:0050794 (regulation of cellular process)
2009-04-03 Deleted RELATION is a GO:0051128 (regulation of cellular component organization)
2008-04-01 Updated RELATION part of GO:0006413 (translational initiation)
2008-04-01 Added RELATION regulates GO:0006413 (translational initiation)
2008-04-01 Deleted RELATION part of GO:0006413 (translational initiation)
2008-04-01 Updated RELATION is a GO:0006417 (regulation of translation)
2008-04-01 Updated RELATION is a GO:0051128 (regulation of cellular component organization)
Timestamp Action Category Detail
Timestamp Action Category Detail
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