GO:0006691
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leukotriene metabolic process
Biological Process
Definition (GO:0006691 GONUTS page)
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
leukotriene metabolism | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006691
Child Term | Relationship to GO:0006691 |
---|---|
leukotriene D4 metabolic process
|
is_a |
leukotriene biosynthetic process
|
is_a |
leukotriene B4 metabolic process
|
is_a |
leukotriene A4 metabolic process
|
is_a |
leukotriene catabolic process
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0006691 | leukotriene metabolic process | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR001446 | 5-lipoxygenase-activating protein |
InterPro | IPR018295 | FLAP/GST2/LTC4S, conserved site |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input_or_output | CHEBI | CHEBI:62942 | leukotriene anion |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006691 based on ALL annotations
The top 100 of 541 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
leukotriene metabolic process
|
29,536.18 | 100.00 | 6,600 | 6,600 |
leukotriene-C4 synthase activity
|
27,741.41 | 37.03 | 2,504 | 2,666 |
leukotriene biosynthetic process
|
16,434.67 | 30.87 | 2,702 | 4,856 |
glutathione peroxidase activity
|
5,548.72 | 18.48 | 6,070 | 32,311 |
glutathione transferase activity
|
1,146.56 | 3.87 | 6,070 | 156,367 |
nuclear envelope
|
1,051.10 | 3.51 | 4,773 | 134,123 |
nuclear outer membrane
|
1,310.64 | 3.35 | 797 | 17,961 |
leukotriene D4 catabolic process
|
27,760.78 | 2.60 | 172 | 183 |
enzyme activator activity
|
801.09 | 2.57 | 2,198 | 81,040 |
leukotriene production involved in inflammatory response
|
29,536.18 | 2.23 | 147 | 147 |
Totals | 51217 | 5498366 |
No co-occurrence statistics for GO:0006691 based on MANUAL annotations
The top 100 of 413 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
leukotriene metabolic process
|
30,041.84 | 100.00 | 43 | 43 |
leukotriene D4 catabolic process
|
27,037.65 | 20.45 | 9 | 10 |
leukotriene transport
|
7,510.46 | 9.84 | 6 | 24 |
ABC-type glutathione S-conjugate transporter activity
|
6,932.73 | 9.52 | 6 | 26 |
ABC-type transporter activity
|
6,675.96 | 9.38 | 6 | 27 |
antibiotic metabolic process
|
6,008.37 | 8.96 | 6 | 30 |
positive regulation of cellular response to macrophage colony-stimulating factor stimulus
|
20,027.89 | 8.89 | 4 | 6 |
positive regulation of matrix metallopeptidase secretion
|
15,020.92 | 8.51 | 4 | 8 |
modified amino acid binding
|
4,291.69 | 7.59 | 6 | 42 |
regulation of dendritic cell cytokine production
|
7,068.67 | 7.14 | 4 | 17 |
Totals | 375 | 4076 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2017-04-15 | Deleted | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
2017-04-06 | Added | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
2017-03-03 | Deleted | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
2016-03-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2012-11-15 | Added | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
2012-10-29 | Deleted | RELATION | is a GO:0043449 (alkene metabolic process) |
2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
2008-04-01 | Updated | RELATION | is a GO:0006690 (icosanoid metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0043449 (alkene metabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-01-15 | Updated | TERM | leukotriene metabolic process |
2002-02-06 | Updated | TERM | leukotriene metabolism |
2001-04-03 | Updated | TERM | leukotriene metabolism |
2001-03-30 | Added | TERM | leukotriene metabolism |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
2007-08-09 | Added | SYNONYM | leukotriene metabolism |
2007-08-09 | Deleted | SYNONYM | leukotriene metabolism |
2007-01-29 | Added | SYNONYM | leukotriene metabolism |
2006-05-04 | Updated | DEFINITION | The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
2005-01-21 | Updated | DEFINITION | The chemical reactions involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
2002-11-27 | Updated | DEFINITION | The chemical reactions and physical changes involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
2001-08-06 | Added | DEFINITION | Metabolism of leukotriene: a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-04-15 | Deleted | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
2017-04-06 | Added | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
2017-03-03 | Deleted | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
2012-11-15 | Added | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
2012-10-29 | Deleted | RELATION | is a GO:0043449 (alkene metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0006690 (icosanoid metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0043449 (alkene metabolic process) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-03-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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