This term is obsolete.

GO:0006691 JSON

leukotriene metabolic process

Biological Process

Definition (GO:0006691 GONUTS page)

The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.

13,714 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
leukotriene metabolism exact

Ancestor Chart

Ancestor chart for GO:0006691
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006691

Child Term Relationship to
GO:0006691
leukotriene D4 metabolic process
is_a
leukotriene biosynthetic process
is_a
leukotriene catabolic process
is_a
leukotriene A4 metabolic process
is_a
leukotriene B4 metabolic process
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0006691 leukotriene metabolic process Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Cross-references

Database ID Description
InterPro IPR001446 5-lipoxygenase-activating protein
InterPro IPR018295 FLAP/GST2/LTC4S, conserved site
Reactome R-HSA-2142691

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input_or_output CHEBI CHEBI:62942 leukotriene anion

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006691 based on ALL annotations
The top 100 of 534 co-occurring terms
Co-occurring Term PR S% #Together #Compared
leukotriene metabolic process
29,187.64 100.00 6,789 6,789
leukotriene-C4 synthase activity
27,510.56 36.85 2,559 2,715
leukotriene biosynthetic process
16,310.74 30.73 2,755 4,930
glutathione peroxidase activity
5,565.76 18.78 6,275 32,907
glutathione transferase activity
1,135.27 3.88 6,275 161,329
nuclear envelope
1,072.85 3.63 4,971 135,239
nuclear outer membrane
1,371.53 3.47 797 16,961
enzyme activator activity
788.13 2.56 2,240 82,956
leukotriene D4 catabolic process
27,413.80 2.50 170 181
leukotriene production involved in inflammatory response
29,187.64 2.17 147 147
Totals 52420 5638700
No co-occurrence statistics for GO:0006691 based on MANUAL annotations
The top 100 of 411 co-occurring terms
Co-occurring Term PR S% #Together #Compared
leukotriene metabolic process
32,826.35 100.00 43 43
leukotriene D4 catabolic process
29,543.71 20.45 9 10
leukotriene transport
8,206.59 9.84 6 24
ABC-type glutathione S-conjugate transporter activity
7,575.31 9.52 6 26
antibiotic metabolic process
6,565.27 8.96 6 30
positive regulation of cellular response to macrophage colony-stimulating factor stimulus
21,884.23 8.89 4 6
ABC-type transporter activity
6,353.49 8.82 6 31
positive regulation of matrix metallopeptidase secretion
16,413.17 8.51 4 8
modified amino acid binding
4,689.48 7.59 6 42
regulation of dendritic cell cytokine production
7,723.85 7.14 4 17
Totals 367 3955

Change Log

Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-2142691
2017-04-15 Deleted RELATION is a GO:0033559 (unsaturated fatty acid metabolic process)
2017-04-06 Added RELATION is a GO:0033559 (unsaturated fatty acid metabolic process)
2017-03-03 Deleted RELATION is a GO:0033559 (unsaturated fatty acid metabolic process)
2016-03-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2012-11-15 Added RELATION is a GO:0033559 (unsaturated fatty acid metabolic process)
2012-10-29 Deleted RELATION is a GO:0043449 (alkene metabolic process)
2008-05-13 Added DEFINITION The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2008-04-01 Updated RELATION is a GO:0006690 (icosanoid metabolic process)
Timestamp Action Category Detail
2007-01-15 Updated TERM leukotriene metabolic process
2002-02-06 Updated TERM leukotriene metabolism
2001-04-03 Updated TERM leukotriene metabolism
2001-03-30 Added TERM leukotriene metabolism
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2007-08-09 Deleted SYNONYM leukotriene metabolism
2007-08-09 Added SYNONYM leukotriene metabolism
2007-01-29 Added SYNONYM leukotriene metabolism
2006-05-04 Updated DEFINITION The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2005-01-21 Updated DEFINITION The chemical reactions involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2002-11-27 Updated DEFINITION The chemical reactions and physical changes involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2001-08-06 Added DEFINITION Metabolism of leukotriene: a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
Timestamp Action Category Detail
2017-04-15 Deleted RELATION is a GO:0033559 (unsaturated fatty acid metabolic process)
2017-04-06 Added RELATION is a GO:0033559 (unsaturated fatty acid metabolic process)
2017-03-03 Deleted RELATION is a GO:0033559 (unsaturated fatty acid metabolic process)
2012-11-15 Added RELATION is a GO:0033559 (unsaturated fatty acid metabolic process)
2012-10-29 Deleted RELATION is a GO:0043449 (alkene metabolic process)
2008-04-01 Updated RELATION is a GO:0006690 (icosanoid metabolic process)
2008-04-01 Updated RELATION is a GO:0043449 (alkene metabolic process)
Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-2142691
Timestamp Action Category Detail
2016-03-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
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