This term is obsolete.

GO:0006704 JSON

glucocorticoid biosynthetic process

Biological Process

Definition (GO:0006704 GONUTS page)

The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.

7,051 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
glucocorticoid synthesis exact
glucocorticoid anabolism exact
glucocorticoid biosynthesis exact
glucocorticoid formation exact

Ancestor Chart

Ancestor chart for GO:0006704
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006704

Child Term Relationship to
GO:0006704
cortisol biosynthetic process
is_a
regulation of glucocorticoid biosynthetic process
regulates
positive regulation of glucocorticoid biosynthetic process
positively_regulates
negative regulation of glucocorticoid biosynthetic process
negatively_regulates

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P95028 83331 P95028_MYCTO GO:0008610 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16952959
NOT-qualified manual protein Q0UV92 321614 Q0UV92_PHANO GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q4WKE9 330879 Q4WKE9_ASPFU GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q5BGM7 227321 Q5BGM7_EMENI GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q6C017 284591 Q6C017_YARLI GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q7SGR1 367110 Q7SGR1_NEUCR GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_output CHEBI CHEBI:24261 glucocorticoid

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006704 based on ALL annotations
The top 100 of 289 co-occurring terms
Co-occurring Term PR S% #Together #Compared
glucocorticoid biosynthetic process
28,207.03 100.00 6,911 6,911
cortisol metabolic process
27,632.88 95.56 6,738 6,878
cellular response to peptide hormone stimulus
26,270.33 90.83 6,728 7,224
C21-steroid hormone biosynthetic process
28,157.10 89.61 6,203 6,214
calcitriol biosynthetic process from calciol
24,446.82 30.74 2,230 2,573
C21-steroid hormone metabolic process
22,769.53 16.75 1,206 1,494
cholesterol monooxygenase (side-chain-cleaving) activity
26,470.08 15.50 1,082 1,153
cholesterol metabolic process
3,297.46 11.66 6,738 57,638
corticosterone 18-monooxygenase activity
28,157.02 8.15 563 564
steroid 11-beta-monooxygenase activity
26,918.38 8.13 564 591
Totals 95640 18774405
No co-occurrence statistics for GO:0006704 based on MANUAL annotations
The top 100 of 174 co-occurring terms
Co-occurring Term PR S% #Together #Compared
glucocorticoid biosynthetic process
18,194.35 100.00 71 71
cortisol metabolic process
16,678.16 58.67 44 48
cellular response to peptide hormone stimulus
8,270.16 36.00 45 99
corticosterone 18-monooxygenase activity
18,194.35 33.80 24 24
C21-steroid hormone biosynthetic process
12,736.05 33.73 28 40
steroid 11-beta-monooxygenase activity
16,612.23 28.77 21 23
aldosterone biosynthetic process
15,283.26 28.00 21 25
steroid 21-monooxygenase activity
18,194.35 25.35 18 18
cholesterol monooxygenase (side-chain-cleaving) activity
10,916.61 18.52 15 25
cholesterol metabolic process
1,660.90 8.64 44 482
Totals 571 17343

Change Log

Timestamp Action Category Detail
2022-09-16 Added RELATION is a GO:0120178 (steroid hormone biosynthetic process)
2022-09-16 Deleted RELATION is a GO:0006694 (steroid biosynthetic process)
2020-06-02 Deleted RELATION is a GO:0120178 (steroid hormone biosynthetic process)
2020-06-02 Added RELATION is a GO:0006694 (steroid biosynthetic process)
2019-05-22 Deleted RELATION is a GO:0006694 (steroid biosynthetic process)
2019-05-22 Added RELATION is a GO:0120178 (steroid hormone biosynthetic process)
2019-05-22 Deleted RELATION is a GO:0042446 (hormone biosynthetic process)
2017-11-29 Added RELATION is a GO:0042446 (hormone biosynthetic process)
2012-10-29 Deleted RELATION is a GO:0006700 (C21-steroid hormone biosynthetic process)
2012-10-29 Added RELATION is a GO:0006694 (steroid biosynthetic process)
Timestamp Action Category Detail
2007-01-15 Updated TERM glucocorticoid biosynthetic process
2002-02-06 Updated TERM glucocorticoid biosynthesis
2001-04-03 Updated TERM glucocorticoid biosynthesis
2001-03-30 Added TERM glucocorticoid biosynthesis
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
2007-08-09 Added SYNONYM glucocorticoid anabolism
2007-08-09 Added SYNONYM glucocorticoid biosynthesis
2007-08-09 Added SYNONYM glucocorticoid formation
2007-08-09 Added SYNONYM glucocorticoid synthesis
2007-08-09 Deleted SYNONYM glucocorticoid synthesis
2007-08-09 Deleted SYNONYM glucocorticoid formation
2007-08-09 Deleted SYNONYM glucocorticoid anabolism
2007-08-09 Deleted SYNONYM glucocorticoid biosynthesis
2007-01-15 Added SYNONYM glucocorticoid biosynthesis
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
2005-08-10 Added SYNONYM glucocorticoid synthesis
2005-08-10 Added SYNONYM glucocorticoid formation
2005-08-10 Added SYNONYM glucocorticoid anabolism
2002-11-27 Added DEFINITION The formation from simpler components of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Timestamp Action Category Detail
2022-09-16 Added RELATION is a GO:0120178 (steroid hormone biosynthetic process)
2022-09-16 Deleted RELATION is a GO:0006694 (steroid biosynthetic process)
2020-06-02 Deleted RELATION is a GO:0120178 (steroid hormone biosynthetic process)
2020-06-02 Added RELATION is a GO:0006694 (steroid biosynthetic process)
2019-05-22 Deleted RELATION is a GO:0006694 (steroid biosynthetic process)
2019-05-22 Added RELATION is a GO:0120178 (steroid hormone biosynthetic process)
2019-05-22 Deleted RELATION is a GO:0042446 (hormone biosynthetic process)
2017-11-29 Added RELATION is a GO:0042446 (hormone biosynthetic process)
2012-10-29 Deleted RELATION is a GO:0006700 (C21-steroid hormone biosynthetic process)
2012-10-29 Added RELATION is a GO:0006694 (steroid biosynthetic process)
2010-09-03 Deleted RELATION is a GO:0044249 (obsolete cellular biosynthetic process)
2010-09-03 Deleted RELATION is a GO:0042446 (hormone biosynthetic process)
2010-08-04 Deleted RELATION is a GO:0006694 (steroid biosynthetic process)
2010-08-04 Added RELATION is a GO:0006700 (C21-steroid hormone biosynthetic process)
2010-02-13 Added RELATION is a GO:0044249 (obsolete cellular biosynthetic process)
2008-04-01 Updated RELATION is a GO:0006694 (steroid biosynthetic process)
2008-04-01 Updated RELATION is a GO:0008211 (glucocorticoid metabolic process)
2008-04-01 Updated RELATION is a GO:0042446 (hormone biosynthetic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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