GO:0006744
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ubiquinone biosynthetic process
Biological Process
Definition (GO:0006744 GONUTS page)
The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ubiquinone synthesis | exact |
ubiquinone formation | exact |
ubiquinone anabolism | exact |
ubiquinone biosynthesis | exact |
coenzyme Q biosynthesis | exact |
coenzyme Q biosynthetic process | exact |
coenzyme Q10 biosynthesis | narrow |
coenzyme Q10 biosynthetic process | narrow |
coenzyme Q6 biosynthesis | narrow |
coenzyme Q6 biosynthetic process | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006744
Child Term | Relationship to GO:0006744 |
---|---|
ubiquinone biosynthesis complex
|
capable_of_part_of |
2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity
|
part_of |
polyprenyldihydroxybenzoate methyltransferase activity
|
part_of |
3-demethylubiquinol 3-O-methyltransferase activity
|
part_of |
positive regulation of ubiquinone biosynthetic process
|
positively_regulates |
negative regulation of ubiquinone biosynthetic process
|
negatively_regulates |
regulation of ubiquinone biosynthetic process
|
regulates |
2-methoxy-6-polyprenolphenol 4-hydroxylase activity
|
part_of |
4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity
|
part_of |
3-demethylubiquinone 3-O-methyltransferase activity
|
part_of |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P97478 | 10090 | COQ7_MOUSE | GO:0006744 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:19478076 | |
NOT-qualified manual | protein | Q63619 | 10116 | COQ7_RAT | GO:0006744 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q76FS5 | 3702 | SPS2_ARATH | GO:0006744 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23913686 | |
NOT-qualified manual | protein | Q8S948 | 3702 | SPS1_ARATH | GO:0006744 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23913686 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000689 | Ubiquinone biosynthesis monooxygenase COQ6 |
InterPro | IPR007440 | Chorismate--pyruvate lyase |
InterPro | IPR007715 | Ubiquinone biosynthesis protein Coq4 |
InterPro | IPR010232 | Probable protein kinase UbiB |
InterPro | IPR010233 | Ubiquinone biosynthesis O-methyltransferase |
InterPro | IPR010971 | Ubiquinone biosynthesis hydroxylase UbiH/COQ6 |
InterPro | IPR011295 | 2-polyprenyl-6-methoxyphenol 4-hydroxylase |
InterPro | IPR011566 | Ubiquinone biosynthesis protein Coq7 |
InterPro | IPR012762 | Ubiquinone biosynthesis protein COQ9 |
InterPro | IPR016830 | Ubiquinone biosynthesis accessory factor UbiT |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_output | CHEBI | CHEBI:16389 | ubiquinones |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:1901006 | obsolete ubiquinone-6 biosynthetic process | replaced_by GO:0006744 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006744 based on ALL annotations
The top 100 of 1,087 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ubiquinone biosynthetic process
|
922.61 | 100.00 | 214,777 | 214,777 |
polyprenyldihydroxybenzoate methyltransferase activity
|
922.57 | 11.01 | 23,653 | 23,654 |
2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity
|
922.61 | 9.48 | 20,354 | 20,354 |
3-demethylubiquinol 3-O-methyltransferase activity
|
922.56 | 9.22 | 19,804 | 19,805 |
4-hydroxybenzoate polyprenyltransferase activity
|
917.73 | 8.66 | 18,614 | 18,713 |
3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
|
909.16 | 8.27 | 17,785 | 18,048 |
ketone biosynthetic process
|
313.78 | 8.09 | 20,623 | 60,637 |
extrinsic component of mitochondrial inner membrane
|
915.32 | 7.31 | 15,701 | 15,826 |
demethylmenaquinone methyltransferase activity
|
418.95 | 6.56 | 15,296 | 33,685 |
3-demethoxyubiquinol 3-hydroxylase activity
|
916.81 | 5.96 | 12,812 | 12,893 |
Totals | 1124128 | 221964679 |
No co-occurrence statistics for GO:0006744 based on MANUAL annotations
The top 100 of 231 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ubiquinone biosynthetic process
|
970.13 | 100.00 | 1,455 | 1,455 |
polyprenyl diphosphate synthase complex
|
970.13 | 11.41 | 166 | 166 |
2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity
|
970.13 | 9.55 | 139 | 139 |
prenyltransferase activity
|
272.37 | 9.31 | 178 | 634 |
isoprenoid biosynthetic process
|
257.29 | 8.83 | 170 | 641 |
3-demethoxyubiquinol 3-hydroxylase activity
|
970.13 | 7.56 | 110 | 110 |
polyprenyldihydroxybenzoate methyltransferase activity
|
814.61 | 7.45 | 110 | 131 |
4-hydroxybenzoate polyprenyltransferase activity
|
970.13 | 7.42 | 108 | 108 |
protein-containing complex binding
|
102.97 | 7.07 | 254 | 2,393 |
carotene biosynthetic process
|
628.45 | 6.82 | 103 | 159 |
Totals | 5010 | 195756 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_pombe | 61 |
goslim_drosophila | 173 |
Change Log
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- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
- Cross-references
- Other
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-2142789 |
2022-01-12 | Added | SUBSET | goslim_drosophila |
2020-05-08 | Added | SUBSET | goslim_pombe |
2020-02-28 | Deleted | XREF | MIPS_funcat:01.20.15.03 |
2019-05-04 | Added | XREF | MIPS_funcat:01.20.15.03 |
2013-10-17 | Deleted | RELATION | is a GO:0045426 (quinone cofactor biosynthetic process) |
2012-11-22 | Deleted | RELATION | is a GO:0042181 (ketone biosynthetic process) |
2012-11-22 | Added | RELATION | is a GO:1901663 (quinone biosynthetic process) |
2012-11-02 | Added | RELATION | is a GO:0042181 (ketone biosynthetic process) |
2008-05-13 | Added | DEFINITION | The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-01-15 | Updated | TERM | ubiquinone biosynthetic process |
2002-02-06 | Updated | TERM | ubiquinone biosynthesis |
2001-04-03 | Updated | TERM | ubiquinone biosynthesis |
2001-03-30 | Added | TERM | ubiquinone biosynthesis |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. |
2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. |
2007-08-09 | Deleted | SYNONYM | coenzyme Q9 biosynthesis |
2007-08-09 | Deleted | SYNONYM | coenzyme Q8 biosynthesis |
2007-08-09 | Deleted | SYNONYM | coenzyme Q6 biosynthesis |
2007-08-09 | Deleted | SYNONYM | coenzyme Q10 biosynthesis |
2007-08-09 | Deleted | SYNONYM | coenzyme Q biosynthesis |
2007-08-09 | Added | SYNONYM | coenzyme Q10 biosynthetic process |
2007-08-09 | Deleted | SYNONYM | ubiquinone synthesis |
2007-08-09 | Deleted | SYNONYM | ubiquinone formation |
2007-08-09 | Deleted | SYNONYM | ubiquinone anabolism |
2007-08-09 | Deleted | SYNONYM | ubiquinone biosynthesis |
2007-08-09 | Deleted | SYNONYM | coenzyme Q9 biosynthetic process |
2007-08-09 | Deleted | SYNONYM | coenzyme Q8 biosynthetic process |
2007-08-09 | Deleted | SYNONYM | coenzyme Q6 biosynthetic process |
2007-08-09 | Deleted | SYNONYM | coenzyme Q10 biosynthetic process |
2007-08-09 | Deleted | SYNONYM | coenzyme Q biosynthetic process |
2007-08-09 | Added | SYNONYM | ubiquinone synthesis |
2007-08-09 | Added | SYNONYM | ubiquinone formation |
2007-08-09 | Added | SYNONYM | ubiquinone biosynthesis |
2007-08-09 | Added | SYNONYM | ubiquinone anabolism |
2007-08-09 | Added | SYNONYM | coenzyme Q9 biosynthetic process |
2007-08-09 | Added | SYNONYM | coenzyme Q9 biosynthesis |
2007-08-09 | Added | SYNONYM | coenzyme Q8 biosynthetic process |
2007-08-09 | Added | SYNONYM | coenzyme Q8 biosynthesis |
2007-08-09 | Added | SYNONYM | coenzyme Q6 biosynthetic process |
2007-08-09 | Added | SYNONYM | coenzyme Q6 biosynthesis |
2007-08-09 | Added | SYNONYM | coenzyme Q10 biosynthesis |
2007-08-09 | Added | SYNONYM | coenzyme Q biosynthesis |
2007-08-09 | Added | SYNONYM | coenzyme Q biosynthetic process |
2007-01-15 | Added | SYNONYM | coenzyme Q10 biosynthetic process |
2007-01-15 | Added | SYNONYM | ubiquinone biosynthesis |
2007-01-15 | Added | SYNONYM | coenzyme Q biosynthetic process |
2007-01-15 | Added | SYNONYM | coenzyme Q6 biosynthetic process |
2007-01-15 | Added | SYNONYM | coenzyme Q9 biosynthetic process |
2007-01-15 | Added | SYNONYM | coenzyme Q8 biosynthetic process |
2006-09-03 | Added | SYNONYM | coenzyme Q8 biosynthesis |
2006-09-03 | Added | SYNONYM | coenzyme Q10 biosynthesis |
2006-09-03 | Added | SYNONYM | coenzyme Q9 biosynthesis |
2006-05-04 | Updated | DEFINITION | The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. |
2005-10-02 | Added | SYNONYM | coenzyme Q biosynthesis |
2005-10-02 | Added | SYNONYM | coenzyme Q6 biosynthesis |
2005-08-10 | Added | SYNONYM | ubiquinone anabolism |
2005-08-10 | Added | SYNONYM | ubiquinone formation |
2005-08-10 | Added | SYNONYM | ubiquinone synthesis |
2004-04-28 | Added | DEFINITION | The formation from simpler components of ubiquinone, a lipid-soluble electron-transporting coenzyme. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-10-17 | Deleted | RELATION | is a GO:0045426 (quinone cofactor biosynthetic process) |
2012-11-22 | Deleted | RELATION | is a GO:0042181 (ketone biosynthetic process) |
2012-11-22 | Added | RELATION | is a GO:1901663 (quinone biosynthetic process) |
2012-11-02 | Added | RELATION | is a GO:0042181 (ketone biosynthetic process) |
2008-04-01 | Updated | RELATION | is a GO:0045426 (quinone cofactor biosynthetic process) |
2008-04-01 | Updated | RELATION | is a GO:0006743 (ubiquinone metabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-2142789 |
2020-02-28 | Deleted | XREF | MIPS_funcat:01.20.15.03 |
2019-05-04 | Added | XREF | MIPS_funcat:01.20.15.03 |
2003-10-27 | Added | XREF | MetaCyc:UBISYN-PWY |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-01-12 | Added | SUBSET | goslim_drosophila |
2020-05-08 | Added | SUBSET | goslim_pombe |
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