This term is obsolete.

GO:0006744 JSON

ubiquinone biosynthetic process

Biological Process

Definition (GO:0006744 GONUTS page)

The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

313,485 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ubiquinone synthesis exact
ubiquinone formation exact
ubiquinone anabolism exact
ubiquinone biosynthesis exact
coenzyme Q biosynthesis exact
coenzyme Q biosynthetic process exact
coenzyme Q10 biosynthesis narrow
coenzyme Q10 biosynthetic process narrow
coenzyme Q6 biosynthesis narrow
coenzyme Q6 biosynthetic process narrow

Ancestor Chart

Ancestor chart for GO:0006744
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006744

Child Term Relationship to
GO:0006744
ubiquinone biosynthesis complex
capable_of_part_of
2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity
part_of
polyprenyldihydroxybenzoate methyltransferase activity
part_of
3-demethylubiquinol 3-O-methyltransferase activity
part_of
positive regulation of ubiquinone biosynthetic process
positively_regulates
negative regulation of ubiquinone biosynthetic process
negatively_regulates
regulation of ubiquinone biosynthetic process
regulates
2-methoxy-6-polyprenolphenol 4-hydroxylase activity
part_of
4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity
part_of
3-demethylubiquinone 3-O-methyltransferase activity
part_of

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P97478 10090 COQ7_MOUSE GO:0006744 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:19478076
NOT-qualified manual protein Q63619 10116 COQ7_RAT GO:0006744 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q76FS5 3702 SPS2_ARATH GO:0006744 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23913686
NOT-qualified manual protein Q8S948 3702 SPS1_ARATH GO:0006744 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23913686

Cross-references

Database ID Description
InterPro IPR000689 Ubiquinone biosynthesis monooxygenase COQ6
InterPro IPR007440 Chorismate--pyruvate lyase
InterPro IPR007715 Ubiquinone biosynthesis protein Coq4
InterPro IPR010232 Probable protein kinase UbiB
InterPro IPR010233 Ubiquinone biosynthesis O-methyltransferase
InterPro IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6
InterPro IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase
InterPro IPR011566 Ubiquinone biosynthesis protein Coq7
InterPro IPR012762 Ubiquinone biosynthesis protein COQ9
InterPro IPR016830 Ubiquinone biosynthesis accessory factor UbiT

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_output CHEBI CHEBI:16389 ubiquinones

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:1901006 obsolete ubiquinone-6 biosynthetic process replaced_by GO:0006744

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006744 based on ALL annotations
The top 100 of 1,087 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ubiquinone biosynthetic process
922.61 100.00 214,777 214,777
polyprenyldihydroxybenzoate methyltransferase activity
922.57 11.01 23,653 23,654
2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity
922.61 9.48 20,354 20,354
3-demethylubiquinol 3-O-methyltransferase activity
922.56 9.22 19,804 19,805
4-hydroxybenzoate polyprenyltransferase activity
917.73 8.66 18,614 18,713
3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
909.16 8.27 17,785 18,048
ketone biosynthetic process
313.78 8.09 20,623 60,637
extrinsic component of mitochondrial inner membrane
915.32 7.31 15,701 15,826
demethylmenaquinone methyltransferase activity
418.95 6.56 15,296 33,685
3-demethoxyubiquinol 3-hydroxylase activity
916.81 5.96 12,812 12,893
Totals 1124128 221964679
No co-occurrence statistics for GO:0006744 based on MANUAL annotations
The top 100 of 231 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ubiquinone biosynthetic process
970.13 100.00 1,455 1,455
polyprenyl diphosphate synthase complex
970.13 11.41 166 166
2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity
970.13 9.55 139 139
prenyltransferase activity
272.37 9.31 178 634
isoprenoid biosynthetic process
257.29 8.83 170 641
3-demethoxyubiquinol 3-hydroxylase activity
970.13 7.56 110 110
polyprenyldihydroxybenzoate methyltransferase activity
814.61 7.45 110 131
4-hydroxybenzoate polyprenyltransferase activity
970.13 7.42 108 108
protein-containing complex binding
102.97 7.07 254 2,393
carotene biosynthetic process
628.45 6.82 103 159
Totals 5010 195756

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_pombe 61
goslim_drosophila 173

Change Log

Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-2142789
2022-01-12 Added SUBSET goslim_drosophila
2020-05-08 Added SUBSET goslim_pombe
2020-02-28 Deleted XREF MIPS_funcat:01.20.15.03
2019-05-04 Added XREF MIPS_funcat:01.20.15.03
2013-10-17 Deleted RELATION is a GO:0045426 (quinone cofactor biosynthetic process)
2012-11-22 Deleted RELATION is a GO:0042181 (ketone biosynthetic process)
2012-11-22 Added RELATION is a GO:1901663 (quinone biosynthetic process)
2012-11-02 Added RELATION is a GO:0042181 (ketone biosynthetic process)
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
Timestamp Action Category Detail
2007-01-15 Updated TERM ubiquinone biosynthetic process
2002-02-06 Updated TERM ubiquinone biosynthesis
2001-04-03 Updated TERM ubiquinone biosynthesis
2001-03-30 Added TERM ubiquinone biosynthesis
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
2007-08-09 Deleted SYNONYM coenzyme Q9 biosynthesis
2007-08-09 Deleted SYNONYM coenzyme Q8 biosynthesis
2007-08-09 Deleted SYNONYM coenzyme Q6 biosynthesis
2007-08-09 Deleted SYNONYM coenzyme Q10 biosynthesis
2007-08-09 Deleted SYNONYM coenzyme Q biosynthesis
2007-08-09 Added SYNONYM coenzyme Q10 biosynthetic process
2007-08-09 Deleted SYNONYM ubiquinone synthesis
2007-08-09 Deleted SYNONYM ubiquinone formation
2007-08-09 Deleted SYNONYM ubiquinone anabolism
2007-08-09 Deleted SYNONYM ubiquinone biosynthesis
2007-08-09 Deleted SYNONYM coenzyme Q9 biosynthetic process
2007-08-09 Deleted SYNONYM coenzyme Q8 biosynthetic process
2007-08-09 Deleted SYNONYM coenzyme Q6 biosynthetic process
2007-08-09 Deleted SYNONYM coenzyme Q10 biosynthetic process
2007-08-09 Deleted SYNONYM coenzyme Q biosynthetic process
2007-08-09 Added SYNONYM ubiquinone synthesis
2007-08-09 Added SYNONYM ubiquinone formation
2007-08-09 Added SYNONYM ubiquinone biosynthesis
2007-08-09 Added SYNONYM ubiquinone anabolism
2007-08-09 Added SYNONYM coenzyme Q9 biosynthetic process
2007-08-09 Added SYNONYM coenzyme Q9 biosynthesis
2007-08-09 Added SYNONYM coenzyme Q8 biosynthetic process
2007-08-09 Added SYNONYM coenzyme Q8 biosynthesis
2007-08-09 Added SYNONYM coenzyme Q6 biosynthetic process
2007-08-09 Added SYNONYM coenzyme Q6 biosynthesis
2007-08-09 Added SYNONYM coenzyme Q10 biosynthesis
2007-08-09 Added SYNONYM coenzyme Q biosynthesis
2007-08-09 Added SYNONYM coenzyme Q biosynthetic process
2007-01-15 Added SYNONYM coenzyme Q10 biosynthetic process
2007-01-15 Added SYNONYM ubiquinone biosynthesis
2007-01-15 Added SYNONYM coenzyme Q biosynthetic process
2007-01-15 Added SYNONYM coenzyme Q6 biosynthetic process
2007-01-15 Added SYNONYM coenzyme Q9 biosynthetic process
2007-01-15 Added SYNONYM coenzyme Q8 biosynthetic process
2006-09-03 Added SYNONYM coenzyme Q8 biosynthesis
2006-09-03 Added SYNONYM coenzyme Q10 biosynthesis
2006-09-03 Added SYNONYM coenzyme Q9 biosynthesis
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
2005-10-02 Added SYNONYM coenzyme Q biosynthesis
2005-10-02 Added SYNONYM coenzyme Q6 biosynthesis
2005-08-10 Added SYNONYM ubiquinone anabolism
2005-08-10 Added SYNONYM ubiquinone formation
2005-08-10 Added SYNONYM ubiquinone synthesis
2004-04-28 Added DEFINITION The formation from simpler components of ubiquinone, a lipid-soluble electron-transporting coenzyme.
Timestamp Action Category Detail
2013-10-17 Deleted RELATION is a GO:0045426 (quinone cofactor biosynthetic process)
2012-11-22 Deleted RELATION is a GO:0042181 (ketone biosynthetic process)
2012-11-22 Added RELATION is a GO:1901663 (quinone biosynthetic process)
2012-11-02 Added RELATION is a GO:0042181 (ketone biosynthetic process)
2008-04-01 Updated RELATION is a GO:0045426 (quinone cofactor biosynthetic process)
2008-04-01 Updated RELATION is a GO:0006743 (ubiquinone metabolic process)
Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-2142789
2020-02-28 Deleted XREF MIPS_funcat:01.20.15.03
2019-05-04 Added XREF MIPS_funcat:01.20.15.03
2003-10-27 Added XREF MetaCyc:UBISYN-PWY
Timestamp Action Category Detail
2022-01-12 Added SUBSET goslim_drosophila
2020-05-08 Added SUBSET goslim_pombe
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