GO:0006768
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biotin metabolic process
Biological Process
Definition (GO:0006768 GONUTS page)
The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
vitamin B7 metabolism | exact |
vitamin B7 metabolic process | exact |
vitamin H metabolic process | exact |
vitamin H metabolism | exact |
biotin metabolism | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006768
Child Term | Relationship to GO:0006768 |
---|---|
biotin biosynthetic process
|
is_a |
biotin catabolic process
|
is_a |
Cross-references
Database | ID | Description |
---|---|---|
Wikipedia | Biotin |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input_or_output | CHEBI | CHEBI:57586 | biotinate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006768 based on ALL annotations
The top 81 of 81 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
biotin metabolic process
|
232,069.98 | 100.00 | 840 | 840 |
pantothenate:sodium symporter activity
|
232,069.98 | 10.48 | 88 | 88 |
amide transmembrane transporter activity
|
212,730.83 | 10.38 | 88 | 96 |
sodium-dependent multivitamin transmembrane transporter activity
|
206,284.44 | 10.34 | 88 | 99 |
sulfur compound transmembrane transporter activity
|
196,366.90 | 10.28 | 88 | 104 |
monocarboxylate:sodium symporter activity
|
109,796.56 | 9.38 | 88 | 186 |
iodide transmembrane transporter activity
|
41,256.89 | 7.06 | 88 | 495 |
transport across blood-brain barrier
|
34,555.26 | 6.55 | 88 | 591 |
iodide transmembrane transport
|
20,902.93 | 5.09 | 88 | 977 |
biotin import across plasma membrane
|
16,576.43 | 4.46 | 89 | 1,246 |
Totals | 4458 | 232305366 |
No co-occurrence statistics for GO:0006768 based on MANUAL annotations
The top 63 of 63 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
biotin metabolic process
|
44,544.79 | 100.00 | 29 | 29 |
response to biotin
|
38,181.25 | 20.00 | 6 | 7 |
biotin binding
|
11,878.61 | 15.69 | 8 | 30 |
biotinidase activity
|
33,408.59 | 10.00 | 3 | 4 |
biotin import across plasma membrane
|
8,352.15 | 7.14 | 3 | 16 |
pantothenate:sodium symporter activity
|
44,544.79 | 6.90 | 2 | 2 |
vitamin transmembrane transporter activity
|
17,817.92 | 6.25 | 2 | 5 |
biotin transmembrane transporter activity
|
5,568.10 | 6.00 | 3 | 24 |
sulfur compound transmembrane transporter activity
|
12,727.08 | 5.88 | 2 | 7 |
amide transmembrane transporter activity
|
12,727.08 | 5.88 | 2 | 7 |
Totals | 183 | 695830 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-13 | Deleted | RELATION | is a GO:1901564 (obsolete organonitrogen compound metabolic process) |
2024-05-30 | Deleted | RELATION | is a GO:1901360 (obsolete organic cyclic compound metabolic process) |
2024-04-17 | Deleted | RELATION | is a GO:0046483 (obsolete heterocycle metabolic process) |
2020-06-02 | Deleted | RELATION | is a GO:0017144 (drug metabolic process) |
2020-05-09 | Deleted | RELATION | is a GO:0006732 (obsolete coenzyme metabolic process) |
2017-11-29 | Added | RELATION | is a GO:0006732 (obsolete coenzyme metabolic process) |
2017-11-29 | Deleted | RELATION | is a GO:0051186 (obsolete cofactor metabolic process) |
2017-11-29 | Added | RELATION | is a GO:0017144 (drug metabolic process) |
2016-11-28 | Added | RELATION | is a GO:1901564 (obsolete organonitrogen compound metabolic process) |
2016-11-28 | Added | RELATION | is a GO:1901360 (obsolete organic cyclic compound metabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-01-15 | Updated | TERM | biotin metabolic process |
2002-02-06 | Updated | TERM | biotin metabolism |
2001-04-03 | Updated | TERM | biotin metabolism |
2001-03-30 | Added | TERM | biotin metabolism |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. |
2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. |
2007-08-09 | Deleted | SYNONYM | vitamin H metabolism |
2007-08-09 | Added | SYNONYM | vitamin H metabolic process |
2007-08-09 | Added | SYNONYM | vitamin B7 metabolism |
2007-08-09 | Added | SYNONYM | vitamin B7 metabolic process |
2007-08-09 | Added | SYNONYM | biotin metabolism |
2007-08-09 | Added | SYNONYM | vitamin H metabolism |
2007-08-09 | Deleted | SYNONYM | vitamin B7 metabolism |
2007-08-09 | Deleted | SYNONYM | vitamin H metabolic process |
2007-08-09 | Deleted | SYNONYM | vitamin B7 metabolic process |
2007-08-09 | Deleted | SYNONYM | biotin metabolism |
2007-01-29 | Added | SYNONYM | biotin metabolism |
2007-01-15 | Added | SYNONYM | vitamin B7 metabolic process |
2007-01-15 | Added | SYNONYM | vitamin H metabolic process |
2006-05-04 | Updated | DEFINITION | The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. |
2005-01-21 | Updated | DEFINITION | The chemical reactions involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. |
2004-10-08 | Added | SYNONYM | vitamin B7 metabolism |
2004-04-19 | Added | SYNONYM | vitamin H metabolism |
2004-04-16 | Deleted | SYNONYM | vitamin H metabolism |
2003-04-24 | Updated | DEFINITION | The chemical reactions and physical changes involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. |
2002-11-27 | Added | DEFINITION | The chemical reactions and physical changes involving biotin, cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. |
2002-07-12 | Added | SYNONYM | vitamin H metabolism |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-13 | Deleted | RELATION | is a GO:1901564 (obsolete organonitrogen compound metabolic process) |
2024-05-30 | Deleted | RELATION | is a GO:1901360 (obsolete organic cyclic compound metabolic process) |
2024-04-17 | Deleted | RELATION | is a GO:0046483 (obsolete heterocycle metabolic process) |
2020-06-02 | Deleted | RELATION | is a GO:0017144 (drug metabolic process) |
2020-05-09 | Deleted | RELATION | is a GO:0006732 (obsolete coenzyme metabolic process) |
2017-11-29 | Added | RELATION | is a GO:0006732 (obsolete coenzyme metabolic process) |
2017-11-29 | Deleted | RELATION | is a GO:0051186 (obsolete cofactor metabolic process) |
2017-11-29 | Added | RELATION | is a GO:0017144 (drug metabolic process) |
2016-11-28 | Added | RELATION | is a GO:1901564 (obsolete organonitrogen compound metabolic process) |
2016-11-28 | Added | RELATION | is a GO:1901360 (obsolete organic cyclic compound metabolic process) |
2016-11-28 | Added | RELATION | is a GO:0046483 (obsolete heterocycle metabolic process) |
2016-11-28 | Added | RELATION | is a GO:0006790 (sulfur compound metabolic process) |
2016-11-28 | Added | RELATION | is a GO:0043603 (amide metabolic process) |
2016-06-22 | Deleted | RELATION | is a GO:1901360 (obsolete organic cyclic compound metabolic process) |
2016-06-22 | Deleted | RELATION | is a GO:1901564 (obsolete organonitrogen compound metabolic process) |
2016-06-22 | Deleted | RELATION | is a GO:0046483 (obsolete heterocycle metabolic process) |
2016-06-22 | Deleted | RELATION | is a GO:0006790 (sulfur compound metabolic process) |
2016-06-22 | Deleted | RELATION | is a GO:0043603 (amide metabolic process) |
2012-11-05 | Added | RELATION | is a GO:1901564 (obsolete organonitrogen compound metabolic process) |
2012-09-19 | Added | RELATION | is a GO:1901360 (obsolete organic cyclic compound metabolic process) |
2009-07-03 | Added | RELATION | is a GO:0043603 (amide metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0046483 (obsolete heterocycle metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0006790 (sulfur compound metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0032787 (monocarboxylic acid metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0006767 (water-soluble vitamin metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0051186 (obsolete cofactor metabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-03-02 | Added | XREF | Wikipedia:Biotin |
Timestamp | Action | Category | Detail |
---|
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