This term is obsolete.

GO:0006768 JSON

biotin metabolic process

Biological Process

Definition (GO:0006768 GONUTS page)

The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.

129,721 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
vitamin B7 metabolism exact
vitamin B7 metabolic process exact
vitamin H metabolic process exact
vitamin H metabolism exact
biotin metabolism exact

Ancestor Chart

Ancestor chart for GO:0006768
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006768

Child Term Relationship to
GO:0006768
biotin biosynthetic process
is_a
biotin catabolic process
is_a

Cross-references

Database ID Description
Wikipedia Biotin

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input_or_output CHEBI CHEBI:57586 biotinate

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006768 based on ALL annotations
The top 81 of 81 co-occurring terms
Co-occurring Term PR S% #Together #Compared
biotin metabolic process
232,069.98 100.00 840 840
pantothenate:sodium symporter activity
232,069.98 10.48 88 88
amide transmembrane transporter activity
212,730.83 10.38 88 96
sodium-dependent multivitamin transmembrane transporter activity
206,284.44 10.34 88 99
sulfur compound transmembrane transporter activity
196,366.90 10.28 88 104
monocarboxylate:sodium symporter activity
109,796.56 9.38 88 186
iodide transmembrane transporter activity
41,256.89 7.06 88 495
transport across blood-brain barrier
34,555.26 6.55 88 591
iodide transmembrane transport
20,902.93 5.09 88 977
biotin import across plasma membrane
16,576.43 4.46 89 1,246
Totals 4458 232305366
No co-occurrence statistics for GO:0006768 based on MANUAL annotations
The top 63 of 63 co-occurring terms
Co-occurring Term PR S% #Together #Compared
biotin metabolic process
44,544.79 100.00 29 29
response to biotin
38,181.25 20.00 6 7
biotin binding
11,878.61 15.69 8 30
biotinidase activity
33,408.59 10.00 3 4
biotin import across plasma membrane
8,352.15 7.14 3 16
pantothenate:sodium symporter activity
44,544.79 6.90 2 2
vitamin transmembrane transporter activity
17,817.92 6.25 2 5
biotin transmembrane transporter activity
5,568.10 6.00 3 24
sulfur compound transmembrane transporter activity
12,727.08 5.88 2 7
amide transmembrane transporter activity
12,727.08 5.88 2 7
Totals 183 695830

Change Log

Timestamp Action Category Detail
2024-07-13 Deleted RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2024-05-30 Deleted RELATION is a GO:1901360 (obsolete organic cyclic compound metabolic process)
2024-04-17 Deleted RELATION is a GO:0046483 (obsolete heterocycle metabolic process)
2020-06-02 Deleted RELATION is a GO:0017144 (drug metabolic process)
2020-05-09 Deleted RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2017-11-29 Added RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2017-11-29 Deleted RELATION is a GO:0051186 (obsolete cofactor metabolic process)
2017-11-29 Added RELATION is a GO:0017144 (drug metabolic process)
2016-11-28 Added RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2016-11-28 Added RELATION is a GO:1901360 (obsolete organic cyclic compound metabolic process)
Timestamp Action Category Detail
2007-01-15 Updated TERM biotin metabolic process
2002-02-06 Updated TERM biotin metabolism
2001-04-03 Updated TERM biotin metabolism
2001-03-30 Added TERM biotin metabolism
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2007-08-09 Deleted SYNONYM vitamin H metabolism
2007-08-09 Added SYNONYM vitamin H metabolic process
2007-08-09 Added SYNONYM vitamin B7 metabolism
2007-08-09 Added SYNONYM vitamin B7 metabolic process
2007-08-09 Added SYNONYM biotin metabolism
2007-08-09 Added SYNONYM vitamin H metabolism
2007-08-09 Deleted SYNONYM vitamin B7 metabolism
2007-08-09 Deleted SYNONYM vitamin H metabolic process
2007-08-09 Deleted SYNONYM vitamin B7 metabolic process
2007-08-09 Deleted SYNONYM biotin metabolism
2007-01-29 Added SYNONYM biotin metabolism
2007-01-15 Added SYNONYM vitamin B7 metabolic process
2007-01-15 Added SYNONYM vitamin H metabolic process
2006-05-04 Updated DEFINITION The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2005-01-21 Updated DEFINITION The chemical reactions involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2004-10-08 Added SYNONYM vitamin B7 metabolism
2004-04-19 Added SYNONYM vitamin H metabolism
2004-04-16 Deleted SYNONYM vitamin H metabolism
2003-04-24 Updated DEFINITION The chemical reactions and physical changes involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2002-11-27 Added DEFINITION The chemical reactions and physical changes involving biotin, cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2002-07-12 Added SYNONYM vitamin H metabolism
Timestamp Action Category Detail
2024-07-13 Deleted RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2024-05-30 Deleted RELATION is a GO:1901360 (obsolete organic cyclic compound metabolic process)
2024-04-17 Deleted RELATION is a GO:0046483 (obsolete heterocycle metabolic process)
2020-06-02 Deleted RELATION is a GO:0017144 (drug metabolic process)
2020-05-09 Deleted RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2017-11-29 Added RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2017-11-29 Deleted RELATION is a GO:0051186 (obsolete cofactor metabolic process)
2017-11-29 Added RELATION is a GO:0017144 (drug metabolic process)
2016-11-28 Added RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2016-11-28 Added RELATION is a GO:1901360 (obsolete organic cyclic compound metabolic process)
2016-11-28 Added RELATION is a GO:0046483 (obsolete heterocycle metabolic process)
2016-11-28 Added RELATION is a GO:0006790 (sulfur compound metabolic process)
2016-11-28 Added RELATION is a GO:0043603 (amide metabolic process)
2016-06-22 Deleted RELATION is a GO:1901360 (obsolete organic cyclic compound metabolic process)
2016-06-22 Deleted RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2016-06-22 Deleted RELATION is a GO:0046483 (obsolete heterocycle metabolic process)
2016-06-22 Deleted RELATION is a GO:0006790 (sulfur compound metabolic process)
2016-06-22 Deleted RELATION is a GO:0043603 (amide metabolic process)
2012-11-05 Added RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2012-09-19 Added RELATION is a GO:1901360 (obsolete organic cyclic compound metabolic process)
2009-07-03 Added RELATION is a GO:0043603 (amide metabolic process)
2008-04-01 Updated RELATION is a GO:0046483 (obsolete heterocycle metabolic process)
2008-04-01 Updated RELATION is a GO:0006790 (sulfur compound metabolic process)
2008-04-01 Updated RELATION is a GO:0032787 (monocarboxylic acid metabolic process)
2008-04-01 Updated RELATION is a GO:0006767 (water-soluble vitamin metabolic process)
2008-04-01 Updated RELATION is a GO:0051186 (obsolete cofactor metabolic process)
Timestamp Action Category Detail
2009-03-02 Added XREF Wikipedia:Biotin
Timestamp Action Category Detail
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