This term is obsolete.

GO:0006885 JSON

regulation of pH

Biological Process

Definition (GO:0006885 GONUTS page)

Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.

186,647 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
hydrogen ion homeostasis exact

Ancestor Chart

Ancestor chart for GO:0006885
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006885

Child Term Relationship to
GO:0006885
pH reduction
is_a
pH elevation
is_a
regulation of cellular pH
is_a

Cross-references

Database ID Description
InterPro IPR001953 Sodium/hydrogen exchanger 2/4
InterPro IPR001970 Sodium/hydrogen exchanger 1-like
InterPro IPR002090 Sodium/hydrogen exchanger 6/7/9
InterPro IPR004670 Na+/H+ antiporter NhaA
InterPro IPR004709 Na+/H+ exchanger
InterPro IPR018410 Na+/H+ exchanger, isoforms 3/5

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006885 based on ALL annotations
The top 100 of 1,020 co-occurring terms
Co-occurring Term PR S% #Together #Compared
regulation of pH
3,556.56 100.00 54,811 54,811
sodium:proton antiporter activity
1,153.50 30.21 44,686 137,779
sodium ion transmembrane transporter activity
1,987.82 27.82 19,538 34,957
potassium:proton antiporter activity
1,152.06 21.67 21,682 66,935
sodium ion import across plasma membrane
1,286.72 20.79 18,000 49,753
regulation of intracellular pH
922.19 17.91 20,109 77,553
sodium ion transport
352.41 9.70 45,006 454,207
inorganic cation transmembrane transport
610.80 8.76 8,311 48,393
antiporter activity
288.21 7.99 46,718 576,507
recycling endosome membrane
446.19 6.75 6,983 55,661
Totals 490777 43396966
No co-occurrence statistics for GO:0006885 based on MANUAL annotations
The top 100 of 591 co-occurring terms
Co-occurring Term PR S% #Together #Compared
regulation of pH
1,453.09 100.00 889 889
inorganic cation transmembrane transport
1,214.21 76.29 798 955
endomembrane system
164.13 11.15 799 7,074
proton transmembrane transporter activity
152.96 1.03 10 95
sodium:proton antiporter activity
28.74 0.95 16 809
carbon dioxide transport
137.66 0.92 9 95
carbonate dehydratase activity
37.18 0.89 12 469
apical plasma membrane
14.87 0.80 32 3,126
potassium:proton antiporter activity
24.66 0.79 13 766
basolateral plasma membrane
15.75 0.79 25 2,306
Totals 3090 49356

Change Log

Timestamp Action Category Detail
2022-12-02 Deleted RELATION is a GO:0055067 (obsolete monovalent inorganic cation homeostasis)
2022-12-02 Added RELATION is a GO:0055080 (monoatomic cation homeostasis)
2022-10-26 Added RELATION is a GO:0065007 (biological regulation)
2009-01-12 Added DEFINITION Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
2009-01-12 Deleted DEFINITION Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
2008-05-13 Added DEFINITION Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
2008-05-12 Deleted DEFINITION Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
2008-04-01 Updated RELATION is a GO:0055067 (obsolete monovalent inorganic cation homeostasis)
2007-12-01 Added SYNONYM hydrogen ion homeostasis
2005-06-30 Updated DEFINITION Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
Timestamp Action Category Detail
2002-07-17 Updated TERM regulation of pH
2002-02-06 Updated TERM pH regulation
2001-04-03 Updated TERM pH regulation
2001-03-30 Added TERM pH regulation
Timestamp Action Category Detail
2009-01-12 Added DEFINITION Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
2009-01-12 Deleted DEFINITION Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
2008-05-13 Added DEFINITION Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
2008-05-12 Deleted DEFINITION Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
2007-12-01 Added SYNONYM hydrogen ion homeostasis
2005-06-30 Updated DEFINITION Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
2002-11-27 Added DEFINITION Any process that modulates the pH of a solution, measured by the concentration of the hydrogen ion.
Timestamp Action Category Detail
2022-12-02 Deleted RELATION is a GO:0055067 (obsolete monovalent inorganic cation homeostasis)
2022-12-02 Added RELATION is a GO:0055080 (monoatomic cation homeostasis)
2022-10-26 Added RELATION is a GO:0065007 (biological regulation)
2008-04-01 Updated RELATION is a GO:0055067 (obsolete monovalent inorganic cation homeostasis)
Timestamp Action Category Detail
Timestamp Action Category Detail
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