This term is obsolete.

GO:0006897 JSON

endocytosis

Biological Process

Definition (GO:0006897 GONUTS page)

A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle.

Secondary IDs

GO:0016193, GO:0016196, GO:0098701

798,619 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
nonselective vesicle endocytosis related
endocytic import into cell exact
plasma membrane invagination narrow
vesicle endocytosis exact

Ancestor Chart

Ancestor chart for GO:0006897
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006897

Child Term Relationship to
GO:0006897
positive regulation of endocytosis
positively_regulates
regulation of endocytosis by exocyst localization
regulates
endocytosis, site selection
part_of
postsynaptic endocytic zone
capable_of
receptor-mediated endocytosis
is_a
Rvs161p-Rvs167p complex
capable_of_part_of
negative regulation of endocytosis
negatively_regulates
ubiquitin-dependent endocytosis
is_a
regulation of endocytosis
regulates
sperm entry
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A9K3Y7P9 10116 A0A9K3Y7P9_RAT GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B2RZ46 10116 B2RZ46_RAT GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O35509 10116 RB11B_RAT GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P35292 10090 RAB17_MOUSE GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9624171
NOT-qualified manual protein P46638 10090 RB11B_MOUSE GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10942597
NOT-qualified manual protein Q0WQ75 3702 VPS51_ARATH GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:24757006
NOT-qualified manual protein Q8MQJ7 7227 Q8MQJ7_DROME GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23406899
NOT-qualified manual protein Q9VU14 7227 Q9VU14_DROME GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23406899

Cross-references

Database ID Description
InterPro IPR003914 Rabaptin
InterPro IPR012320 Stonin homology
InterPro IPR012466 NECAP, PHear domain
InterPro IPR025604 Actin cytoskeleton-regulatory complex protein End3
InterPro IPR029282 Equatorin
InterPro IPR030224 Sla2 family
InterPro IPR032469 Endophilin-A3, BAR domain
InterPro IPR037425 Sorting nexin-9, BAR domain
InterPro IPR037426 Sorting nexin-9, PX domain
InterPro IPR037427 Sorting nexin-33, BAR domain

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0008549 obsolete dynamin GTPase activity consider GO:0006897
GO:0044397 obsolete actin cortical patch internalization replaced_by GO:0006897

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006897 based on ALL annotations
The top 100 of 4,616 co-occurring terms
Co-occurring Term PR S% #Together #Compared
endocytosis
772.71 100.00 256,442 256,442
clathrin-coated pit
349.29 10.66 31,380 69,420
endosomal transport
277.87 9.97 31,082 86,435
clathrin-coated vesicle
354.48 8.96 25,701 56,024
clathrin binding
237.58 8.29 26,159 85,079
actin filament organization
135.66 7.63 30,487 173,652
clathrin vesicle coat
573.17 7.39 19,455 26,228
endosome
80.81 7.32 50,312 481,072
clathrin-dependent endocytosis
295.01 6.90 19,927 52,194
plasma membrane tubulation
608.87 6.85 17,898 22,714
Totals 1504017 16929192
No co-occurrence statistics for GO:0006897 based on MANUAL annotations
The top 100 of 2,931 co-occurring terms
Co-occurring Term PR S% #Together #Compared
endocytosis
297.48 100.00 4,745 4,745
endosomal transport
92.22 9.56 576 1,858
clathrin binding
129.76 8.98 482 1,105
clathrin vesicle coat
152.97 8.74 452 879
endosome
35.05 7.54 821 6,968
actin filament organization
40.06 6.92 592 4,396
phospholipid binding
59.57 6.90 452 2,257
endocytic vesicle
65.07 5.34 313 1,431
early endosome
32.92 4.80 371 3,353
signal transduction
16.33 4.79 1,300 23,676
Totals 27046 645996

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_yeast 163

Change Log

Timestamp Action Category Detail
2023-05-16 Added RELATION is a GO:0098657 (import into cell)
2023-03-06 Added DEFINITION A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle.
2023-03-06 Deleted DEFINITION A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
2020-02-28 Deleted XREF MIPS_funcat:20.09.18.09.01
2020-02-07 Deleted RELATION is a GO:0098657 (import into cell)
2019-05-04 Added XREF MIPS_funcat:20.09.18.09.01
2018-12-25 Added RELATION has part GO:0001881 (receptor recycling)
2017-10-14 Added SYNONYM plasma membrane invagination
2017-10-14 Added SECONDARY GO:0098701 (endocytic import into cell)
2017-10-14 Added RELATION is a GO:0098657 (import into cell)
Timestamp Action Category Detail
2002-02-06 Updated TERM endocytosis
2001-04-03 Updated TERM endocytosis
2001-03-30 Added TERM endocytosis
Timestamp Action Category Detail
2023-03-06 Added DEFINITION A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle.
2023-03-06 Deleted DEFINITION A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
2017-10-14 Added SYNONYM plasma membrane invagination
2017-10-14 Deleted SYNONYM plasma membrane invagination
2017-10-14 Added SYNONYM endocytic import into cell
2010-11-14 Deleted DEFINITION A type of vesicle-mediated transport in which cells take up external materials or membrane constituents by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle.
2010-11-14 Added DEFINITION A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
2008-10-24 Deleted DEFINITION A type of vesicle-mediated transport in which cells take up external materials by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle.
2008-10-24 Added DEFINITION A type of vesicle-mediated transport in which cells take up external materials or membrane constituents by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle.
2008-10-02 Added DEFINITION A type of vesicle-mediated transport in which cells take up external materials by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle.
2008-10-02 Deleted DEFINITION The uptake of external materials by cells by the invagination of small region of the plasma membrane to form a new intracellular membrane-limited vesicle.
2008-05-13 Added DEFINITION The uptake of external materials by cells by the invagination of small region of the plasma membrane to form a new intracellular membrane-limited vesicle.
2008-05-12 Deleted DEFINITION The uptake of external materials by cells by the invagination of small region of the plasma membrane to form a new intracellular membrane-limited vesicle.
2007-08-09 Deleted SYNONYM plasma membrane invagination
2007-08-09 Deleted SYNONYM nonselective vesicle endocytosis
2007-08-09 Deleted SYNONYM vesicle endocytosis
2007-08-09 Added SYNONYM vesicle endocytosis
2007-08-09 Added SYNONYM plasma membrane invagination
2007-08-09 Added SYNONYM nonselective vesicle endocytosis
2007-07-11 Deleted SYNONYM dynamin GTPase activity
2007-01-25 Added SYNONYM plasma membrane invagination
2005-08-10 Added SYNONYM dynamin GTPase activity
2004-04-19 Added SYNONYM vesicle endocytosis
2004-04-16 Deleted SYNONYM vesicle endocytosis
2004-01-23 Added SYNONYM nonselective vesicle endocytosis
2002-11-27 Added DEFINITION The uptake of external materials by cells by the invagination of small region of the plasma membrane to form a new intracellular membrane-limited vesicle.
2002-04-22 Added SYNONYM vesicle endocytosis
Timestamp Action Category Detail
2023-05-16 Added RELATION is a GO:0098657 (import into cell)
2020-02-07 Deleted RELATION is a GO:0098657 (import into cell)
2018-12-25 Added RELATION has part GO:0001881 (receptor recycling)
2017-10-14 Added RELATION is a GO:0098657 (import into cell)
2012-03-29 Deleted RELATION is a GO:0010324 (membrane invagination)
2008-04-01 Updated RELATION is a GO:0010324 (membrane invagination)
2008-04-01 Updated RELATION is a GO:0016192 (vesicle-mediated transport)
Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:20.09.18.09.01
2019-05-04 Added XREF MIPS_funcat:20.09.18.09.01
2009-03-02 Added XREF Wikipedia:Endocytosis
Timestamp Action Category Detail
2017-10-14 Added SECONDARY GO:0098701 (endocytic import into cell)
2013-04-18 Updated SUBSET goslim_yeast
2011-08-14 Added SUBSET goslim_yeast
2004-01-23 Added SECONDARY GO:0016193 (nonselective vesicle endocytosis)
2002-04-22 Added SECONDARY GO:0016196 (vesicle endocytosis)
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