This term is obsolete.

GO:0006911 JSON

phagocytosis, engulfment

Biological Process

Definition (GO:0006911 GONUTS page)

The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.

12,324 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
phagosome biosynthesis related
phagosome formation related

Ancestor Chart

Ancestor chart for GO:0006911
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006911

Child Term Relationship to
GO:0006911
engulfment of apoptotic cell
is_a
negative regulation of phagocytosis, engulfment
negatively_regulates
regulation of phagocytosis, engulfment
regulates
positive regulation of phagocytosis, engulfment
positively_regulates
membrane reorganization involved in phagocytosis, engulfment
part_of
cytoskeletal rearrangement involved in phagocytosis, engulfment
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0006911 phagocytosis, engulfment Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A9K3Y7P9 10116 A0A9K3Y7P9_RAT GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B2RZ46 10116 B2RZ46_RAT GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O35509 10116 RB11B_RAT GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P35292 10090 RAB17_MOUSE GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9624171
NOT-qualified manual protein P46638 10090 RB11B_MOUSE GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10942597
NOT-qualified manual protein Q0WQ75 3702 VPS51_ARATH GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:24757006
NOT-qualified manual protein Q8MQJ7 7227 Q8MQJ7_DROME GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23406899
NOT-qualified manual protein Q9VU14 7227 Q9VU14_DROME GO:0006897 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23406899

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0006912 obsolete phagosome formation consider GO:0006911

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006911 based on ALL annotations
The top 100 of 1,289 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phagocytosis, engulfment
52,318.51 100.00 3,726 3,726
phagocytic cup
25,090.41 36.74 2,277 4,748
podosome assembly
37,217.73 25.18 1,045 1,469
negative regulation of small GTPase mediated signal transduction
33,816.01 24.84 1,071 1,657
positive regulation of mast cell activation
17,946.18 8.27 366 1,067
virus receptor activity
8,380.67 7.38 449 2,803
podosome
3,694.37 6.08 1,138 16,116
positive regulation of protein processing in phagocytic vesicle
52,318.52 5.07 189 189
plasma membrane tubulation
2,461.85 4.20 1,045 22,208
positive regulation of reactive oxygen species biosynthetic process
10,802.08 3.80 166 804
Totals 21175 209844
No co-occurrence statistics for GO:0006911 based on MANUAL annotations
The top 100 of 1,190 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phagocytosis, engulfment
5,294.26 100.00 244 244
phagocytic cup
2,015.58 20.49 75 197
amyloid-beta clearance
2,156.92 11.30 33 81
positive regulation of protein processing in phagocytic vesicle
5,294.26 9.43 23 23
phagocytosis, recognition
1,985.35 9.34 27 72
podosome assembly
2,079.89 7.91 22 56
complement-mediated synapse pruning
3,811.87 7.17 18 25
microglial cell activation
1,127.48 6.99 23 108
integrin alphaM-beta2 complex
5,294.26 6.97 17 17
positive regulation of smooth muscle cell chemotaxis
3,750.10 6.77 17 24
Totals 1673 8911

Change Log

Timestamp Action Category Detail
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2023-03-06 Deleted RELATION part of GO:0006897 (endocytosis)
2018-12-25 Added RELATION part of GO:0006897 (endocytosis)
2016-08-02 Deleted RELATION is a GO:0010324 (membrane invagination)
2016-08-02 Added RELATION is a GO:0099024 (plasma membrane invagination)
2008-05-13 Added DEFINITION The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
2008-05-12 Deleted DEFINITION The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
2008-04-01 Updated RELATION is a GO:0010324 (membrane invagination)
2008-04-01 Updated RELATION part of GO:0006909 (phagocytosis)
2007-08-09 Added SYNONYM phagosome biosynthesis
Timestamp Action Category Detail
2002-02-06 Updated TERM phagocytosis, engulfment
2001-04-03 Updated TERM phagocytosis, engulfment
2001-03-30 Added TERM phagocytosis, engulfment
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
2008-05-12 Deleted DEFINITION The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
2007-08-09 Added SYNONYM phagosome biosynthesis
2007-08-09 Deleted SYNONYM phagosome biosynthesis
2007-08-09 Deleted SYNONYM phagosome formation
2007-08-09 Added SYNONYM phagosome formation
2007-01-15 Added SYNONYM phagosome biosynthesis
2006-05-26 Updated DEFINITION The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
2005-08-10 Added SYNONYM phagosome formation
2004-04-24 Added DEFINITION The internalization of bacteria, immune complexes, and other particulate matter by phagocytosis including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocyte, or induced uptake via an enhanced membrane ruffling of the phagocyte similar to macropinocytosis.
Timestamp Action Category Detail
2023-03-06 Deleted RELATION part of GO:0006897 (endocytosis)
2018-12-25 Added RELATION part of GO:0006897 (endocytosis)
2016-08-02 Deleted RELATION is a GO:0010324 (membrane invagination)
2016-08-02 Added RELATION is a GO:0099024 (plasma membrane invagination)
2008-04-01 Updated RELATION is a GO:0010324 (membrane invagination)
2008-04-01 Updated RELATION part of GO:0006909 (phagocytosis)
Timestamp Action Category Detail
Timestamp Action Category Detail
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
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