GO:0006911
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phagocytosis, engulfment
Biological Process
Definition (GO:0006911 GONUTS page)
The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
phagosome biosynthesis | related |
phagosome formation | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006911
Child Term | Relationship to GO:0006911 |
---|---|
engulfment of apoptotic cell
|
is_a |
negative regulation of phagocytosis, engulfment
|
negatively_regulates |
regulation of phagocytosis, engulfment
|
regulates |
positive regulation of phagocytosis, engulfment
|
positively_regulates |
membrane reorganization involved in phagocytosis, engulfment
|
part_of |
cytoskeletal rearrangement involved in phagocytosis, engulfment
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0006911 | phagocytosis, engulfment | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A9K3Y7P9 | 10116 | A0A9K3Y7P9_RAT | GO:0006897 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | B2RZ46 | 10116 | B2RZ46_RAT | GO:0006897 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | O35509 | 10116 | RB11B_RAT | GO:0006897 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P35292 | 10090 | RAB17_MOUSE | GO:0006897 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9624171 | |
NOT-qualified manual | protein | P46638 | 10090 | RB11B_MOUSE | GO:0006897 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10942597 | |
NOT-qualified manual | protein | Q0WQ75 | 3702 | VPS51_ARATH | GO:0006897 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:24757006 | |
NOT-qualified manual | protein | Q8MQJ7 | 7227 | Q8MQJ7_DROME | GO:0006897 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23406899 | |
NOT-qualified manual | protein | Q9VU14 | 7227 | Q9VU14_DROME | GO:0006897 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23406899 |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0006912 | obsolete phagosome formation | consider GO:0006911 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006911 based on ALL annotations
The top 100 of 1,289 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phagocytosis, engulfment
|
52,318.51 | 100.00 | 3,726 | 3,726 |
phagocytic cup
|
25,090.41 | 36.74 | 2,277 | 4,748 |
podosome assembly
|
37,217.73 | 25.18 | 1,045 | 1,469 |
negative regulation of small GTPase mediated signal transduction
|
33,816.01 | 24.84 | 1,071 | 1,657 |
positive regulation of mast cell activation
|
17,946.18 | 8.27 | 366 | 1,067 |
virus receptor activity
|
8,380.67 | 7.38 | 449 | 2,803 |
podosome
|
3,694.37 | 6.08 | 1,138 | 16,116 |
positive regulation of protein processing in phagocytic vesicle
|
52,318.52 | 5.07 | 189 | 189 |
plasma membrane tubulation
|
2,461.85 | 4.20 | 1,045 | 22,208 |
positive regulation of reactive oxygen species biosynthetic process
|
10,802.08 | 3.80 | 166 | 804 |
Totals | 21175 | 209844 |
No co-occurrence statistics for GO:0006911 based on MANUAL annotations
The top 100 of 1,190 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phagocytosis, engulfment
|
5,294.26 | 100.00 | 244 | 244 |
phagocytic cup
|
2,015.58 | 20.49 | 75 | 197 |
amyloid-beta clearance
|
2,156.92 | 11.30 | 33 | 81 |
positive regulation of protein processing in phagocytic vesicle
|
5,294.26 | 9.43 | 23 | 23 |
phagocytosis, recognition
|
1,985.35 | 9.34 | 27 | 72 |
podosome assembly
|
2,079.89 | 7.91 | 22 | 56 |
complement-mediated synapse pruning
|
3,811.87 | 7.17 | 18 | 25 |
microglial cell activation
|
1,127.48 | 6.99 | 23 | 108 |
integrin alphaM-beta2 complex
|
5,294.26 | 6.97 | 17 | 17 |
positive regulation of smooth muscle cell chemotaxis
|
3,750.10 | 6.77 | 17 | 24 |
Totals | 1673 | 8911 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-11-01 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2023-03-06 | Deleted | RELATION | part of GO:0006897 (endocytosis) |
2018-12-25 | Added | RELATION | part of GO:0006897 (endocytosis) |
2016-08-02 | Deleted | RELATION | is a GO:0010324 (membrane invagination) |
2016-08-02 | Added | RELATION | is a GO:0099024 (plasma membrane invagination) |
2008-05-13 | Added | DEFINITION | The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. |
2008-05-12 | Deleted | DEFINITION | The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. |
2008-04-01 | Updated | RELATION | is a GO:0010324 (membrane invagination) |
2008-04-01 | Updated | RELATION | part of GO:0006909 (phagocytosis) |
2007-08-09 | Added | SYNONYM | phagosome biosynthesis |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | phagocytosis, engulfment |
2001-04-03 | Updated | TERM | phagocytosis, engulfment |
2001-03-30 | Added | TERM | phagocytosis, engulfment |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. |
2008-05-12 | Deleted | DEFINITION | The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. |
2007-08-09 | Added | SYNONYM | phagosome biosynthesis |
2007-08-09 | Deleted | SYNONYM | phagosome biosynthesis |
2007-08-09 | Deleted | SYNONYM | phagosome formation |
2007-08-09 | Added | SYNONYM | phagosome formation |
2007-01-15 | Added | SYNONYM | phagosome biosynthesis |
2006-05-26 | Updated | DEFINITION | The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. |
2005-08-10 | Added | SYNONYM | phagosome formation |
2004-04-24 | Added | DEFINITION | The internalization of bacteria, immune complexes, and other particulate matter by phagocytosis including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocyte, or induced uptake via an enhanced membrane ruffling of the phagocyte similar to macropinocytosis. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-03-06 | Deleted | RELATION | part of GO:0006897 (endocytosis) |
2018-12-25 | Added | RELATION | part of GO:0006897 (endocytosis) |
2016-08-02 | Deleted | RELATION | is a GO:0010324 (membrane invagination) |
2016-08-02 | Added | RELATION | is a GO:0099024 (plasma membrane invagination) |
2008-04-01 | Updated | RELATION | is a GO:0010324 (membrane invagination) |
2008-04-01 | Updated | RELATION | part of GO:0006909 (phagocytosis) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-11-01 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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