GO:0007194
JSON
negative regulation of adenylate cyclase activity
Biological Process
Definition (GO:0007194 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
Restrictions
This term should not be used for direct annotation.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
inhibition of adenylate cyclase activity | narrow |
negative regulation of adenylyl cyclase activity | exact |
down-regulation of adenylate cyclase activity | exact |
downregulation of adenylate cyclase activity | exact |
down regulation of adenylate cyclase activity | exact |
adenylate cyclase inhibitor | related |
Ancestor Chart
Ancestor chart for GO:0007194
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Describing enzyme functions that catalyse multi-stage reactions | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR003906 | Galanin receptor 1 |
InterPro | IPR003907 | Galanin receptor 2 |
InterPro | IPR003908 | Galanin receptor 3 |
InterPro | IPR008109 | P2Y13 purinoceptor |
InterPro | IPR026919 | Adhesion G-protein coupled receptor V1 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0007194 based on ALL annotations
The top 100 of 346 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of adenylate cyclase activity
|
10,829,933.00 | 100.00 | 18 | 18 |
amylase secretion
|
10,829,932.00 | 11.11 | 2 | 2 |
postsynaptic neurotransmitter receptor cycle
|
2,707,483.00 | 8.33 | 2 | 8 |
postsynaptic recycling endosome membrane
|
802,217.25 | 5.88 | 4 | 54 |
response to endothelin
|
2,707,483.00 | 4.76 | 1 | 4 |
positive regulation of NMDA glutamate receptor activity
|
1,082,993.20 | 3.70 | 1 | 10 |
intracellular anatomical structure
|
601,662.94 | 2.86 | 1 | 18 |
positive regulation of penile erection
|
492,269.66 | 2.56 | 1 | 22 |
positive regulation of endosome to plasma membrane protein transport
|
240,665.17 | 1.89 | 2 | 90 |
chemokine (C-C motif) ligand 12 binding
|
196,907.86 | 1.39 | 1 | 55 |
Totals | 148 | 46871 |
No co-occurrence statistics for GO:0007194 based on MANUAL annotations
The top 100 of 237 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of adenylate cyclase activity
|
71,766.61 | 100.00 | 18 | 18 |
amylase secretion
|
71,766.61 | 11.11 | 2 | 2 |
postsynaptic neurotransmitter receptor cycle
|
20,504.75 | 8.70 | 2 | 7 |
positive regulation of endosome to plasma membrane protein transport
|
13,048.48 | 7.41 | 2 | 11 |
adenylate cyclase inhibitor activity
|
6,945.16 | 6.52 | 3 | 31 |
USH2 complex
|
9,568.88 | 6.45 | 2 | 15 |
clustering of voltage-gated potassium channels
|
9,568.88 | 6.45 | 2 | 15 |
stereocilia ankle link
|
7,974.07 | 5.88 | 2 | 18 |
positive regulation of protein kinase A signaling
|
6,834.92 | 5.41 | 2 | 21 |
T-helper 17 cell chemotaxis
|
23,922.21 | 5.00 | 1 | 3 |
Totals | 173 | 7109 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-26 | Deleted | SUBSET | gocheck_do_not_annotate |
2024-07-26 | Added | SUBSET | gocheck_obsoletion_candidate |
2023-06-13 | Added | SUBSET | gocheck_do_not_annotate |
2018-05-16 | Deleted | RELATION | is a GO:0030818 (obsolete negative regulation of cAMP biosynthetic process) |
2012-05-27 | Added | RELATION | has part GO:0007193 (adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway) |
2011-11-24 | Added | RELATION | is a GO:0030818 (obsolete negative regulation of cAMP biosynthetic process) |
2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity. |
2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity. |
2010-06-15 | Added | RELATION | negatively regulates GO:0004016 (adenylate cyclase activity) |
2010-06-14 | Deleted | RELATION | negatively regulates GO:0004016 (adenylate cyclase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-06-09 | Updated | TERM | negative regulation of adenylate cyclase activity |
2010-06-08 | Updated | TERM | negative regulation of adenylate cyclase activity |
2009-02-25 | Updated | TERM | negative regulation of adenylate cyclase activity |
2009-02-22 | Updated | TERM | negative regulation of adenylate cyclase activity |
2002-08-20 | Updated | TERM | negative regulation of adenylate cyclase activity |
2002-07-15 | Updated | TERM | negative regulation of adenylate cyclase |
2002-02-06 | Updated | TERM | adenylate cyclase inhibition |
2001-04-03 | Updated | TERM | adenylate cyclase inhibition |
2001-03-30 | Added | TERM | adenylate cyclase inhibition |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity. |
2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity. |
2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity. |
2007-08-09 | Deleted | SYNONYM | down regulation of adenylate cyclase activity |
2007-08-09 | Deleted | SYNONYM | down-regulation of adenylate cyclase activity |
2007-08-09 | Deleted | SYNONYM | downregulation of adenylate cyclase activity |
2007-08-09 | Deleted | SYNONYM | inhibition of adenylate cyclase activity |
2007-08-09 | Deleted | SYNONYM | adenylate cyclase inhibitor |
2007-08-09 | Deleted | SYNONYM | negative regulation of adenylyl cyclase activity |
2007-08-09 | Added | SYNONYM | inhibition of adenylate cyclase activity |
2007-08-09 | Added | SYNONYM | negative regulation of adenylyl cyclase activity |
2007-08-09 | Added | SYNONYM | adenylate cyclase inhibitor |
2007-08-09 | Added | SYNONYM | down regulation of adenylate cyclase activity |
2007-08-09 | Added | SYNONYM | down-regulation of adenylate cyclase activity |
2007-08-09 | Added | SYNONYM | downregulation of adenylate cyclase activity |
2007-02-23 | Added | SYNONYM | inhibition of adenylate cyclase activity |
2007-02-23 | Added | SYNONYM | downregulation of adenylate cyclase activity |
2007-02-23 | Added | SYNONYM | down-regulation of adenylate cyclase activity |
2007-02-23 | Added | SYNONYM | down regulation of adenylate cyclase activity |
2006-05-04 | Updated | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity. |
2005-10-21 | Updated | DEFINITION | Any process that stops, prevents or reduces the rate, frequency or extent of adenylate cyclase activity. |
2005-08-15 | Added | SYNONYM | adenylate cyclase inhibitor |
2004-09-03 | Added | SYNONYM | negative regulation of adenylyl cyclase activity |
2002-11-27 | Added | DEFINITION | Any process that stops, prevents or reduces the rate of adenylate cyclase activity. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-05-16 | Deleted | RELATION | is a GO:0030818 (obsolete negative regulation of cAMP biosynthetic process) |
2012-05-27 | Added | RELATION | has part GO:0007193 (adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway) |
2011-11-24 | Added | RELATION | is a GO:0030818 (obsolete negative regulation of cAMP biosynthetic process) |
2010-06-15 | Added | RELATION | negatively regulates GO:0004016 (adenylate cyclase activity) |
2010-06-14 | Deleted | RELATION | negatively regulates GO:0004016 (adenylate cyclase activity) |
2010-06-08 | Added | RELATION | negatively regulates GO:0004016 (adenylate cyclase activity) |
2009-02-25 | Deleted | RELATION | negatively regulates GO:0004016 (adenylate cyclase activity) |
2009-02-22 | Added | RELATION | negatively regulates GO:0004016 (adenylate cyclase activity) |
2008-04-01 | Updated | RELATION | is a GO:0051350 (negative regulation of lyase activity) |
2008-04-01 | Updated | RELATION | is a GO:0045761 (regulation of adenylate cyclase activity) |
2008-04-01 | Updated | RELATION | is a GO:0031280 (negative regulation of cyclase activity) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-26 | Deleted | SUBSET | gocheck_do_not_annotate |
2024-07-26 | Added | SUBSET | gocheck_obsoletion_candidate |
2023-06-13 | Added | SUBSET | gocheck_do_not_annotate |
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