This term is obsolete.

GO:0007194 JSON

negative regulation of adenylate cyclase activity

Biological Process

Definition (GO:0007194 GONUTS page)

Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.

Restrictions

This term should not be used for direct annotation.

19 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
inhibition of adenylate cyclase activity narrow
negative regulation of adenylyl cyclase activity exact
down-regulation of adenylate cyclase activity exact
downregulation of adenylate cyclase activity exact
down regulation of adenylate cyclase activity exact
adenylate cyclase inhibitor related

Ancestor Chart

Ancestor chart for GO:0007194
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Describing enzyme functions that catalyse multi-stage reactions Link

Cross-references

Database ID Description
InterPro IPR003906 Galanin receptor 1
InterPro IPR003907 Galanin receptor 2
InterPro IPR003908 Galanin receptor 3
InterPro IPR008109 P2Y13 purinoceptor
InterPro IPR026919 Adhesion G-protein coupled receptor V1

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0007194 based on ALL annotations
The top 100 of 346 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of adenylate cyclase activity
10,829,933.00 100.00 18 18
amylase secretion
10,829,932.00 11.11 2 2
postsynaptic neurotransmitter receptor cycle
2,707,483.00 8.33 2 8
postsynaptic recycling endosome membrane
802,217.25 5.88 4 54
response to endothelin
2,707,483.00 4.76 1 4
positive regulation of NMDA glutamate receptor activity
1,082,993.20 3.70 1 10
intracellular anatomical structure
601,662.94 2.86 1 18
positive regulation of penile erection
492,269.66 2.56 1 22
positive regulation of endosome to plasma membrane protein transport
240,665.17 1.89 2 90
chemokine (C-C motif) ligand 12 binding
196,907.86 1.39 1 55
Totals 148 46871
No co-occurrence statistics for GO:0007194 based on MANUAL annotations
The top 100 of 237 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of adenylate cyclase activity
71,766.61 100.00 18 18
amylase secretion
71,766.61 11.11 2 2
postsynaptic neurotransmitter receptor cycle
20,504.75 8.70 2 7
positive regulation of endosome to plasma membrane protein transport
13,048.48 7.41 2 11
adenylate cyclase inhibitor activity
6,945.16 6.52 3 31
USH2 complex
9,568.88 6.45 2 15
clustering of voltage-gated potassium channels
9,568.88 6.45 2 15
stereocilia ankle link
7,974.07 5.88 2 18
positive regulation of protein kinase A signaling
6,834.92 5.41 2 21
T-helper 17 cell chemotaxis
23,922.21 5.00 1 3
Totals 173 7109

Change Log

Timestamp Action Category Detail
2024-07-26 Deleted SUBSET gocheck_do_not_annotate
2024-07-26 Added SUBSET gocheck_obsoletion_candidate
2023-06-13 Added SUBSET gocheck_do_not_annotate
2018-05-16 Deleted RELATION is a GO:0030818 (obsolete negative regulation of cAMP biosynthetic process)
2012-05-27 Added RELATION has part GO:0007193 (adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)
2011-11-24 Added RELATION is a GO:0030818 (obsolete negative regulation of cAMP biosynthetic process)
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2010-06-15 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
Timestamp Action Category Detail
2010-06-09 Updated TERM negative regulation of adenylate cyclase activity
2010-06-08 Updated TERM negative regulation of adenylate cyclase activity
2009-02-25 Updated TERM negative regulation of adenylate cyclase activity
2009-02-22 Updated TERM negative regulation of adenylate cyclase activity
2002-08-20 Updated TERM negative regulation of adenylate cyclase activity
2002-07-15 Updated TERM negative regulation of adenylate cyclase
2002-02-06 Updated TERM adenylate cyclase inhibition
2001-04-03 Updated TERM adenylate cyclase inhibition
2001-03-30 Added TERM adenylate cyclase inhibition
Timestamp Action Category Detail
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2007-08-09 Deleted SYNONYM down regulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM down-regulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM downregulation of adenylate cyclase activity
2007-08-09 Deleted SYNONYM inhibition of adenylate cyclase activity
2007-08-09 Deleted SYNONYM adenylate cyclase inhibitor
2007-08-09 Deleted SYNONYM negative regulation of adenylyl cyclase activity
2007-08-09 Added SYNONYM inhibition of adenylate cyclase activity
2007-08-09 Added SYNONYM negative regulation of adenylyl cyclase activity
2007-08-09 Added SYNONYM adenylate cyclase inhibitor
2007-08-09 Added SYNONYM down regulation of adenylate cyclase activity
2007-08-09 Added SYNONYM down-regulation of adenylate cyclase activity
2007-08-09 Added SYNONYM downregulation of adenylate cyclase activity
2007-02-23 Added SYNONYM inhibition of adenylate cyclase activity
2007-02-23 Added SYNONYM downregulation of adenylate cyclase activity
2007-02-23 Added SYNONYM down-regulation of adenylate cyclase activity
2007-02-23 Added SYNONYM down regulation of adenylate cyclase activity
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of adenylate cyclase activity.
2005-08-15 Added SYNONYM adenylate cyclase inhibitor
2004-09-03 Added SYNONYM negative regulation of adenylyl cyclase activity
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of adenylate cyclase activity.
Timestamp Action Category Detail
2018-05-16 Deleted RELATION is a GO:0030818 (obsolete negative regulation of cAMP biosynthetic process)
2012-05-27 Added RELATION has part GO:0007193 (adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)
2011-11-24 Added RELATION is a GO:0030818 (obsolete negative regulation of cAMP biosynthetic process)
2010-06-15 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2010-06-08 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2009-02-22 Added RELATION negatively regulates GO:0004016 (adenylate cyclase activity)
2008-04-01 Updated RELATION is a GO:0051350 (negative regulation of lyase activity)
2008-04-01 Updated RELATION is a GO:0045761 (regulation of adenylate cyclase activity)
2008-04-01 Updated RELATION is a GO:0031280 (negative regulation of cyclase activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-07-26 Deleted SUBSET gocheck_do_not_annotate
2024-07-26 Added SUBSET gocheck_obsoletion_candidate
2023-06-13 Added SUBSET gocheck_do_not_annotate
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