This term is obsolete.

GO:0007266 JSON

Rho protein signal transduction

Biological Process

Definition (GO:0007266 GONUTS page)

An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal.

47,163 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
Rho mediated signal transduction exact

Ancestor Chart

Ancestor chart for GO:0007266
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007266

Child Term Relationship to
GO:0007266
negative regulation of Rho protein signal transduction
negatively_regulates
positive regulation of Rho protein signal transduction
positively_regulates
regulation of Rho protein signal transduction
regulates
Cdc42 protein signal transduction
is_a

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein B0BN43 10116 B0BN43_RAT GO:0007266 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein G3V9K5 10116 G3V9K5_RAT GO:0007266 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein M0RBE8 10116 M0RBE8_RAT GO:0007266 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P42768 9606 WASP_HUMAN GO:0007266 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:8625410

Cross-references

Database ID Description
InterPro IPR000406 Rho protein GDP-dissociation inhibitor
InterPro IPR000469 G-protein alpha subunit, group 12/13
InterPro IPR028557 Unconventional myosin-IXb, Rho-GAP domain
InterPro IPR030045 Alpha-catulin 1
InterPro IPR037310 Rho-associated protein kinase 1, HR1
InterPro IPR037311 Rho-associated protein kinase 2, HR1 domain
InterPro IPR037801 ARHGEF12, PH domain
InterPro IPR037803 Rho guanine nucleotide exchange factor 11, PH domain

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0007266 based on ALL annotations
The top 100 of 1,872 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Rho protein signal transduction
4,212.80 100.00 46,273 46,273
Rho GDP-dissociation inhibitor activity
4,206.27 15.31 7,088 7,099
regulation of cell junction assembly
4,058.26 11.30 5,252 5,452
mitotic cytokinesis
888.88 11.02 8,673 41,105
embryonic morphogenesis
1,766.62 9.81 5,254 12,529
positive regulation of ruffle assembly
3,709.76 9.24 4,329 4,916
regulation of Rho protein signal transduction
1,009.89 9.24 6,045 25,217
positive regulation of pseudopodium assembly
3,845.50 8.17 3,811 4,175
regulation of cell size
2,472.53 7.37 3,596 6,127
centralspindlin complex
4,053.80 7.20 3,340 3,471
Totals 340418 16767690
No co-occurrence statistics for GO:0007266 based on MANUAL annotations
The top 100 of 1,496 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Rho protein signal transduction
1,233.81 100.00 1,047 1,047
Rho GDP-dissociation inhibitor activity
1,220.10 25.43 267 270
regulation of Rho protein signal transduction
255.81 8.42 130 627
positive regulation of pseudopodium assembly
854.92 8.10 88 127
positive regulation of ruffle assembly
765.50 7.73 85 137
positive regulation of actin filament polymerization
233.77 6.28 90 475
ruffle membrane
214.58 6.20 92 529
Rho-dependent protein serine/threonine kinase activity
1,233.81 5.73 60 60
regulation of cell junction assembly
787.54 5.55 60 94
mitotic cytokinesis
117.00 5.25 110 1,160
Totals 4971 63836

Change Log

Timestamp Action Category Detail
2023-12-15 Deleted RELATION is a GO:0007265 (Ras protein signal transduction)
2023-12-15 Added DEFINITION An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal.
2023-12-15 Added RELATION is a GO:0007264 (small GTPase-mediated signal transduction)
2023-12-15 Deleted DEFINITION The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2022-03-14 Deleted DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2022-03-14 Added DEFINITION The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2008-05-13 Added DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2008-05-12 Deleted DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2008-04-01 Updated RELATION is a GO:0007265 (Ras protein signal transduction)
2007-08-09 Deleted SYNONYM Rho mediated signal transduction
Timestamp Action Category Detail
2002-06-06 Updated TERM Rho protein signal transduction
2002-02-06 Updated TERM RHO protein signal transduction
2001-04-03 Updated TERM RHO protein signal transduction
2001-03-30 Added TERM RHO protein signal transduction
Timestamp Action Category Detail
2023-12-15 Added DEFINITION An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal.
2023-12-15 Deleted DEFINITION The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2022-03-14 Deleted DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2022-03-14 Added DEFINITION The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2008-05-13 Added DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2008-05-12 Deleted DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2007-08-09 Deleted SYNONYM Rho mediated signal transduction
2007-08-09 Added SYNONYM Rho mediated signal transduction
2005-03-14 Added SYNONYM Rho mediated signal transduction
2004-08-20 Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2003-09-18 Added DEFINITION A series of reactions within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
Timestamp Action Category Detail
2023-12-15 Deleted RELATION is a GO:0007265 (Ras protein signal transduction)
2023-12-15 Added RELATION is a GO:0007264 (small GTPase-mediated signal transduction)
2008-04-01 Updated RELATION is a GO:0007265 (Ras protein signal transduction)
Timestamp Action Category Detail
Timestamp Action Category Detail
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