GO:0007266
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Rho protein signal transduction
Biological Process
Definition (GO:0007266 GONUTS page)
An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
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Rho mediated signal transduction | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0007266
Child Term | Relationship to GO:0007266 |
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negative regulation of Rho protein signal transduction
|
negatively_regulates |
positive regulation of Rho protein signal transduction
|
positively_regulates |
regulation of Rho protein signal transduction
|
regulates |
Cdc42 protein signal transduction
|
is_a |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | B0BN43 | 10116 | B0BN43_RAT | GO:0007266 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | G3V9K5 | 10116 | G3V9K5_RAT | GO:0007266 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | M0RBE8 | 10116 | M0RBE8_RAT | GO:0007266 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P42768 | 9606 | WASP_HUMAN | GO:0007266 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:8625410 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000406 | Rho protein GDP-dissociation inhibitor |
InterPro | IPR000469 | G-protein alpha subunit, group 12/13 |
InterPro | IPR028557 | Unconventional myosin-IXb, Rho-GAP domain |
InterPro | IPR030045 | Alpha-catulin 1 |
InterPro | IPR037310 | Rho-associated protein kinase 1, HR1 |
InterPro | IPR037311 | Rho-associated protein kinase 2, HR1 domain |
InterPro | IPR037801 | ARHGEF12, PH domain |
InterPro | IPR037803 | Rho guanine nucleotide exchange factor 11, PH domain |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0007266 based on ALL annotations
The top 100 of 1,872 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Rho protein signal transduction
|
4,212.80 | 100.00 | 46,273 | 46,273 |
Rho GDP-dissociation inhibitor activity
|
4,206.27 | 15.31 | 7,088 | 7,099 |
regulation of cell junction assembly
|
4,058.26 | 11.30 | 5,252 | 5,452 |
mitotic cytokinesis
|
888.88 | 11.02 | 8,673 | 41,105 |
embryonic morphogenesis
|
1,766.62 | 9.81 | 5,254 | 12,529 |
positive regulation of ruffle assembly
|
3,709.76 | 9.24 | 4,329 | 4,916 |
regulation of Rho protein signal transduction
|
1,009.89 | 9.24 | 6,045 | 25,217 |
positive regulation of pseudopodium assembly
|
3,845.50 | 8.17 | 3,811 | 4,175 |
regulation of cell size
|
2,472.53 | 7.37 | 3,596 | 6,127 |
centralspindlin complex
|
4,053.80 | 7.20 | 3,340 | 3,471 |
Totals | 340418 | 16767690 |
No co-occurrence statistics for GO:0007266 based on MANUAL annotations
The top 100 of 1,496 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Rho protein signal transduction
|
1,233.81 | 100.00 | 1,047 | 1,047 |
Rho GDP-dissociation inhibitor activity
|
1,220.10 | 25.43 | 267 | 270 |
regulation of Rho protein signal transduction
|
255.81 | 8.42 | 130 | 627 |
positive regulation of pseudopodium assembly
|
854.92 | 8.10 | 88 | 127 |
positive regulation of ruffle assembly
|
765.50 | 7.73 | 85 | 137 |
positive regulation of actin filament polymerization
|
233.77 | 6.28 | 90 | 475 |
ruffle membrane
|
214.58 | 6.20 | 92 | 529 |
Rho-dependent protein serine/threonine kinase activity
|
1,233.81 | 5.73 | 60 | 60 |
regulation of cell junction assembly
|
787.54 | 5.55 | 60 | 94 |
mitotic cytokinesis
|
117.00 | 5.25 | 110 | 1,160 |
Totals | 4971 | 63836 |
Change Log
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Timestamp | Action | Category | Detail |
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2023-12-15 | Deleted | RELATION | is a GO:0007265 (Ras protein signal transduction) |
2023-12-15 | Added | DEFINITION | An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal. |
2023-12-15 | Added | RELATION | is a GO:0007264 (small GTPase-mediated signal transduction) |
2023-12-15 | Deleted | DEFINITION | The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2022-03-14 | Deleted | DEFINITION | A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2022-03-14 | Added | DEFINITION | The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2008-05-13 | Added | DEFINITION | A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2008-05-12 | Deleted | DEFINITION | A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2008-04-01 | Updated | RELATION | is a GO:0007265 (Ras protein signal transduction) |
2007-08-09 | Deleted | SYNONYM | Rho mediated signal transduction |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-06-06 | Updated | TERM | Rho protein signal transduction |
2002-02-06 | Updated | TERM | RHO protein signal transduction |
2001-04-03 | Updated | TERM | RHO protein signal transduction |
2001-03-30 | Added | TERM | RHO protein signal transduction |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-15 | Added | DEFINITION | An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal. |
2023-12-15 | Deleted | DEFINITION | The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2022-03-14 | Deleted | DEFINITION | A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2022-03-14 | Added | DEFINITION | The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2008-05-13 | Added | DEFINITION | A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2008-05-12 | Deleted | DEFINITION | A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2007-08-09 | Deleted | SYNONYM | Rho mediated signal transduction |
2007-08-09 | Added | SYNONYM | Rho mediated signal transduction |
2005-03-14 | Added | SYNONYM | Rho mediated signal transduction |
2004-08-20 | Updated | DEFINITION | A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
2003-09-18 | Added | DEFINITION | A series of reactions within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-15 | Deleted | RELATION | is a GO:0007265 (Ras protein signal transduction) |
2023-12-15 | Added | RELATION | is a GO:0007264 (small GTPase-mediated signal transduction) |
2008-04-01 | Updated | RELATION | is a GO:0007265 (Ras protein signal transduction) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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