This term is obsolete.

GO:0007342 JSON

fusion of sperm to egg plasma membrane involved in single fertilization

Biological Process

Definition (GO:0007342 GONUTS page)

The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head. PMID:17644969

5,477 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
sperm-oocyte fusion narrow

Ancestor Chart

Ancestor chart for GO:0007342
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007342

Child Term Relationship to
GO:0007342
regulation of fusion of sperm to egg plasma membrane
regulates
negative regulation of fusion of sperm to egg plasma membrane
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization Never in Taxon 58024 Spermatophyta
GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2K1K3 10116 A0A0G2K1K3_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8948454
NOT-qualified manual protein A0A8I6A5G9 10116 A0A8I6A5G9_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8948454
NOT-qualified manual protein A0A8I6GLI8 10116 A0A8I6GLI8_RAT GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZCG9 10116 D3ZCG9_RAT GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZQM3 10116 D3ZQM3_RAT GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein I4DUB5 10116 I4DUB5_RAT GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q62470 10090 ITA3_MOUSE GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:12591243
NOT-qualified manual protein Q6IN37 10116 Q6IN37_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8948454
NOT-qualified manual protein Q8CJH4 10116 Q8CJH4_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8948454
NOT-qualified manual protein Q9ES54 10116 NPL4_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10811609

Cross-references

Database ID Description
InterPro IPR000775 Bindin
InterPro IPR001439 Hyaluronidase PH20/Hyaluronidase-5
InterPro IPR026743 Sperm equatorial segment protein 1
InterPro IPR027984 TMEM95 family
InterPro IPR029282 Equatorin
InterPro IPR031684 Sperm-egg fusion protein LLCFC1
InterPro IPR032700 Izumo sperm-egg fusion protein 1
InterPro IPR034549 Sperm acrosome membrane-associated protein 6
InterPro IPR038813 Fertilization-influencing membrane protein

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0007342 based on ALL annotations
The top 100 of 313 co-occurring terms
Co-occurring Term PR S% #Together #Compared
fusion of sperm to egg plasma membrane involved in single fertilization
36,836.50 100.00 5,292 5,292
sperm-egg recognition
24,297.03 27.25 1,678 2,544
acrosomal membrane
8,561.17 10.41 839 3,610
protein binding involved in heterotypic cell-cell adhesion
30,019.00 10.08 546 670
acrosomal vesicle
2,643.45 6.18 1,631 22,728
heterotypic cell-cell adhesion
3,566.72 5.26 546 5,639
hyaluronan catabolic process
3,007.26 5.10 634 7,766
hyalurononglucosaminidase activity
2,497.39 4.60 664 9,794
sperm plasma membrane
4,978.35 4.19 303 2,242
acrosomal vesicle exocytosis
13,246.97 3.32 187 520
Totals 23436 4014557
No co-occurrence statistics for GO:0007342 based on MANUAL annotations
The top 100 of 228 co-occurring terms
Co-occurring Term PR S% #Together #Compared
fusion of sperm to egg plasma membrane involved in single fertilization
5,641.04 100.00 229 229
sperm-egg recognition
4,734.45 38.06 94 112
protein binding involved in heterotypic cell-cell adhesion
3,484.17 8.68 21 34
acrosomal membrane
1,128.21 8.60 30 150
acrosomal vesicle
521.63 7.64 70 757
folic acid binding
1,625.39 6.27 17 59
lysozyme activity
514.55 5.42 27 296
folic acid transport
2,216.12 4.47 11 28
outer acrosomal membrane
1,772.90 4.35 11 35
heterotypic cell-cell adhesion
578.57 4.34 16 156
Totals 1192 38238

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon:58024 (Spermatophyta)
2017-09-07 Updated TERM fusion of sperm to egg plasma membrane involved in single fertilization
2017-09-07 Added DEFINITION The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
2017-09-07 Deleted DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2010-10-01 Added RELATION is a GO:0022412 (cellular process involved in reproduction in multicellular organism)
2008-05-13 Added DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2008-05-12 Deleted DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2008-04-01 Updated RELATION is a GO:0045026 (plasma membrane fusion)
2008-04-01 Updated RELATION part of GO:0007338 (single fertilization)
Timestamp Action Category Detail
2017-09-07 Updated TERM fusion of sperm to egg plasma membrane involved in single fertilization
2003-10-18 Updated TERM fusion of sperm to egg plasma membrane
2002-02-06 Updated TERM binding/fusion of sperm to egg plasma membrane
2001-04-03 Updated TERM binding/fusion of sperm to egg plasma membrane
2001-03-30 Added TERM binding/fusion of sperm to egg plasma membrane
Timestamp Action Category Detail
2017-09-07 Added DEFINITION The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
2017-09-07 Deleted DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2008-05-13 Added DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2008-05-12 Deleted DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2007-08-09 Added SYNONYM sperm-oocyte fusion
2007-08-09 Deleted SYNONYM sperm-oocyte fusion
2004-04-19 Added SYNONYM sperm-oocyte fusion
2004-04-16 Deleted SYNONYM sperm-oocyte fusion
2003-10-22 Added DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2003-10-22 Added SYNONYM sperm-oocyte fusion
Timestamp Action Category Detail
2010-10-01 Added RELATION is a GO:0022412 (cellular process involved in reproduction in multicellular organism)
2008-04-01 Updated RELATION is a GO:0045026 (plasma membrane fusion)
2008-04-01 Updated RELATION part of GO:0007338 (single fertilization)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon:58024 (Spermatophyta)
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