This term is obsolete.

GO:0007342 JSON

fusion of sperm to egg plasma membrane involved in single fertilization

Biological Process

Definition (GO:0007342 GONUTS page)

The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head. PMID:17644969

5,574 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
sperm-oocyte fusion narrow

Ancestor Chart

Ancestor chart for GO:0007342
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007342

Child Term Relationship to
GO:0007342
GO:0043012
regulation of fusion of sperm to egg plasma membrane
regulates
GO:0043013
negative regulation of fusion of sperm to egg plasma membrane
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization Never in Taxon 58024 Spermatophyta
GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2K1K3 10116 A0A0G2K1K3_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8948454
NOT-qualified manual protein A0A8I6A5G9 10116 A0A8I6A5G9_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8948454
NOT-qualified manual protein A0A8I6GLI8 10116 A0A8I6GLI8_RAT GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZCG9 10116 D3ZCG9_RAT GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZQM3 10116 D3ZQM3_RAT GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein I4DUB5 10116 I4DUB5_RAT GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q62470 10090 ITA3_MOUSE GO:0007342 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:12591243
NOT-qualified manual protein Q6IN37 10116 Q6IN37_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8948454
NOT-qualified manual protein Q8CJH4 10116 Q8CJH4_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8948454
NOT-qualified manual protein Q9ES54 10116 NPL4_RAT GO:0061025 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10811609

Cross-references

Database ID Description
InterPro IPR000775 Bindin
InterPro IPR001439 Hyaluronidase PH20/Hyaluronidase-5
InterPro IPR026743 Sperm equatorial segment protein 1
InterPro IPR027984 TMEM95 family
InterPro IPR029282 Equatorin
InterPro IPR031684 Sperm-egg fusion protein LLCFC1
InterPro IPR032700 Izumo sperm-egg fusion protein 1
InterPro IPR034549 Sperm acrosome membrane-associated protein 6
InterPro IPR038813 Fertilization-influencing membrane protein

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0007342 based on ALL annotations
The top 100 of 316 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0007342
fusion of sperm to egg plasma membrane involved in single fertilization
36,920.97 100.00 5,367 5,367
GO:0035036
sperm-egg recognition
23,358.98 27.57 1,762 2,785
GO:0002080
acrosomal membrane
8,556.92 10.47 861 3,715
GO:0086080
protein binding involved in heterotypic cell-cell adhesion
29,619.22 9.16 503 627
GO:0001669
acrosomal vesicle
2,765.94 6.41 1,653 22,065
GO:0030214
hyaluronan catabolic process
2,999.54 5.08 641 7,890
GO:0034113
heterotypic cell-cell adhesion
3,292.78 4.79 503 5,640
GO:0004415
hyalurononglucosaminidase activity
2,482.43 4.57 669 9,950
GO:0097524
sperm plasma membrane
4,885.66 4.16 307 2,320
GO:0007338
single fertilization
1,534.25 3.47 930 22,380
Totals 23860 3791122
No co-occurrence statistics for GO:0007342 based on MANUAL annotations
The top 100 of 231 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0007342
fusion of sperm to egg plasma membrane involved in single fertilization
5,557.22 100.00 254 254
GO:0035036
sperm-egg recognition
4,534.69 36.82 102 125
GO:0002080
acrosomal membrane
1,183.15 8.78 33 155
GO:0001669
acrosomal vesicle
546.16 8.10 80 814
GO:0086080
protein binding involved in heterotypic cell-cell adhesion
3,226.77 6.74 18 31
GO:0003796
lysozyme activity
530.07 5.66 31 325
GO:0005542
folic acid binding
1,296.68 4.67 14 60
GO:0002081
outer acrosomal membrane
1,852.41 4.64 13 39
GO:0034113
heterotypic cell-cell adhesion
577.37 4.08 16 154
GO:0015884
folic acid transport
2,183.19 4.06 11 28
Totals 1264 43245

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon:58024 (Spermatophyta)
2017-09-07 Added DEFINITION The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
2017-09-07 Deleted DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2017-09-07 Updated TERM fusion of sperm to egg plasma membrane involved in single fertilization
2010-10-01 Added RELATION is a GO:0022412 (cellular process involved in reproduction in multicellular organism)
2008-05-13 Added DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2008-05-12 Deleted DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2008-04-01 Updated RELATION is a GO:0045026 (plasma membrane fusion)
2008-04-01 Updated RELATION part of GO:0007338 (single fertilization)
Timestamp Action Category Detail
2017-09-07 Updated TERM fusion of sperm to egg plasma membrane involved in single fertilization
2003-10-18 Updated TERM fusion of sperm to egg plasma membrane
2002-02-06 Updated TERM binding/fusion of sperm to egg plasma membrane
2001-04-03 Updated TERM binding/fusion of sperm to egg plasma membrane
2001-03-30 Added TERM binding/fusion of sperm to egg plasma membrane
Timestamp Action Category Detail
2017-09-07 Added DEFINITION The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
2017-09-07 Deleted DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2008-05-13 Added DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2008-05-12 Deleted DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2007-08-09 Added SYNONYM sperm-oocyte fusion
2007-08-09 Deleted SYNONYM sperm-oocyte fusion
2004-04-19 Added SYNONYM sperm-oocyte fusion
2004-04-16 Deleted SYNONYM sperm-oocyte fusion
2003-10-22 Added SYNONYM sperm-oocyte fusion
2003-10-22 Added DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
Timestamp Action Category Detail
2010-10-01 Added RELATION is a GO:0022412 (cellular process involved in reproduction in multicellular organism)
2008-04-01 Updated RELATION is a GO:0045026 (plasma membrane fusion)
2008-04-01 Updated RELATION part of GO:0007338 (single fertilization)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2023-11-01 Added CONSTRAINT never_in_taxon NCBITaxon:58024 (Spermatophyta)
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