This term is obsolete.
Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'.

GO:0007501 JSON

mesodermal cell fate specification

Biological Process

Definition (GO:0007501 GONUTS page)

The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.

Comments

Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'.

685 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
mesoderm cell fate specification exact

Ancestor Chart

Ancestor chart for GO:0007501
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007501

Child Term Relationship to
GO:0007501
positive regulation of mesodermal cell fate specification
positively_regulates
intermediate mesodermal cell fate specification
is_a
axial mesodermal cell fate specification
is_a
paraxial mesodermal cell fate specification
is_a
lateral mesodermal cell fate specification
is_a
regulation of mesodermal cell fate specification
regulates
negative regulation of mesodermal cell fate specification
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0007501 mesodermal cell fate specification Only in Taxon 6072 Eumetazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_specification_of CL CL:0000222 mesodermal cell

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0060803 obsolete BMP signaling pathway involved in mesodermal cell fate specification consider GO:0007501

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0007501 based on ALL annotations
The top 100 of 418 co-occurring terms
Co-occurring Term PR S% #Together #Compared
mesodermal cell fate specification
338,726.25 100.00 585 585
negative regulation of dermatome development
338,726.25 17.09 100 100
positive regulation of chondrocyte development
331,595.20 15.84 93 95
nephron morphogenesis
338,726.28 15.73 92 92
regulation of branching involved in ureteric bud morphogenesis
338,726.28 15.73 92 92
regulation of midbrain dopaminergic neuron differentiation
182,110.90 14.90 100 186
regulation of chondrocyte differentiation
73,035.39 14.71 185 858
mesenchymal cell differentiation involved in kidney development
214,915.98 14.42 92 145
mesenchymal stem cell maintenance involved in nephron morphogenesis
175,072.00 13.71 92 178
Wnt signaling pathway involved in somitogenesis
134,415.19 13.57 100 252
Totals 9149 193643
No co-occurrence statistics for GO:0007501 based on MANUAL annotations
The top 100 of 380 co-occurring terms
Co-occurring Term PR S% #Together #Compared
mesodermal cell fate specification
30,685.50 100.00 46 46
mesenchymal to epithelial transition involved in metanephros morphogenesis
13,808.48 15.79 9 20
positive regulation of optic nerve formation
30,685.50 13.04 6 6
optic nerve structural organization
23,014.13 12.50 6 8
regulation of metanephros size
23,014.13 12.50 6 8
positive regulation of metanephric DCT cell differentiation
18,411.30 12.00 6 10
negative regulation of apoptotic process involved in metanephric collecting duct development
18,411.30 12.00 6 10
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
18,411.30 12.00 6 10
positive regulation of metanephric glomerulus development
16,737.55 11.76 6 11
optic chiasma development
16,737.55 11.76 6 11
Totals 530 4825

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
2013-11-28 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2013-03-11 Deleted RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2012-12-21 Added RELATION is a GO:0044767 (single-organism developmental process)
2012-10-29 Added RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2010-12-01 Deleted DEFINITION Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2010-12-01 Added DEFINITION The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2008-05-13 Added DEFINITION Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2008-05-12 Deleted DEFINITION Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2008-04-01 Updated RELATION is a GO:0001708 (cell fate specification)
Timestamp Action Category Detail
2005-05-07 Updated TERM mesodermal cell fate specification
2002-07-16 Updated TERM mesoderm cell fate specification
2002-07-15 Updated TERM mesoderm cell fate commitment
2002-02-06 Updated TERM fate specification in mesoderm
2001-04-03 Updated TERM fate specification in mesoderm
2001-03-30 Added TERM fate specification in mesoderm
Timestamp Action Category Detail
2010-12-01 Deleted DEFINITION Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2010-12-01 Added DEFINITION The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2008-05-13 Added DEFINITION Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2008-05-12 Deleted DEFINITION Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2007-08-09 Added SYNONYM mesoderm cell fate specification
2007-08-09 Deleted SYNONYM mesoderm cell fate specification
2005-10-20 Added SYNONYM mesoderm cell fate specification
2004-05-09 Updated DEFINITION Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2002-11-27 Added DEFINITION The process involved in the specification of cell identity in the mesoderm. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
Timestamp Action Category Detail
2013-11-28 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2013-03-11 Deleted RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2012-12-21 Added RELATION is a GO:0044767 (single-organism developmental process)
2012-10-29 Added RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2008-04-01 Updated RELATION is a GO:0001708 (cell fate specification)
2008-04-01 Updated RELATION part of GO:0001710 (mesodermal cell fate commitment)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
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