Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'.
GO:0007501
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mesodermal cell fate specification
Biological Process
Definition (GO:0007501 GONUTS page)
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Comments
Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
mesoderm cell fate specification | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0007501
Child Term | Relationship to GO:0007501 |
---|---|
positive regulation of mesodermal cell fate specification
|
positively_regulates |
intermediate mesodermal cell fate specification
|
is_a |
axial mesodermal cell fate specification
|
is_a |
paraxial mesodermal cell fate specification
|
is_a |
lateral mesodermal cell fate specification
|
is_a |
regulation of mesodermal cell fate specification
|
regulates |
negative regulation of mesodermal cell fate specification
|
negatively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0007501 | mesodermal cell fate specification | Only in Taxon | 6072 | Eumetazoa |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
results_in_specification_of | CL | CL:0000222 | mesodermal cell |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0060803 | obsolete BMP signaling pathway involved in mesodermal cell fate specification | consider GO:0007501 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0007501 based on ALL annotations
The top 100 of 418 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
mesodermal cell fate specification
|
338,726.25 | 100.00 | 585 | 585 |
negative regulation of dermatome development
|
338,726.25 | 17.09 | 100 | 100 |
positive regulation of chondrocyte development
|
331,595.20 | 15.84 | 93 | 95 |
nephron morphogenesis
|
338,726.28 | 15.73 | 92 | 92 |
regulation of branching involved in ureteric bud morphogenesis
|
338,726.28 | 15.73 | 92 | 92 |
regulation of midbrain dopaminergic neuron differentiation
|
182,110.90 | 14.90 | 100 | 186 |
regulation of chondrocyte differentiation
|
73,035.39 | 14.71 | 185 | 858 |
mesenchymal cell differentiation involved in kidney development
|
214,915.98 | 14.42 | 92 | 145 |
mesenchymal stem cell maintenance involved in nephron morphogenesis
|
175,072.00 | 13.71 | 92 | 178 |
Wnt signaling pathway involved in somitogenesis
|
134,415.19 | 13.57 | 100 | 252 |
Totals | 9149 | 193643 |
No co-occurrence statistics for GO:0007501 based on MANUAL annotations
The top 100 of 380 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
mesodermal cell fate specification
|
30,685.50 | 100.00 | 46 | 46 |
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
13,808.48 | 15.79 | 9 | 20 |
positive regulation of optic nerve formation
|
30,685.50 | 13.04 | 6 | 6 |
optic nerve structural organization
|
23,014.13 | 12.50 | 6 | 8 |
regulation of metanephros size
|
23,014.13 | 12.50 | 6 | 8 |
positive regulation of metanephric DCT cell differentiation
|
18,411.30 | 12.00 | 6 | 10 |
negative regulation of apoptotic process involved in metanephric collecting duct development
|
18,411.30 | 12.00 | 6 | 10 |
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
|
18,411.30 | 12.00 | 6 | 10 |
positive regulation of metanephric glomerulus development
|
16,737.55 | 11.76 | 6 | 11 |
optic chiasma development
|
16,737.55 | 11.76 | 6 | 11 |
Totals | 530 | 4825 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
2013-11-28 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2013-03-11 | Deleted | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2012-12-21 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2012-10-29 | Added | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2010-12-01 | Deleted | DEFINITION | Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2010-12-01 | Added | DEFINITION | The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2008-05-13 | Added | DEFINITION | Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2008-05-12 | Deleted | DEFINITION | Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2008-04-01 | Updated | RELATION | is a GO:0001708 (cell fate specification) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-05-07 | Updated | TERM | mesodermal cell fate specification |
2002-07-16 | Updated | TERM | mesoderm cell fate specification |
2002-07-15 | Updated | TERM | mesoderm cell fate commitment |
2002-02-06 | Updated | TERM | fate specification in mesoderm |
2001-04-03 | Updated | TERM | fate specification in mesoderm |
2001-03-30 | Added | TERM | fate specification in mesoderm |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-12-01 | Deleted | DEFINITION | Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2010-12-01 | Added | DEFINITION | The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2008-05-13 | Added | DEFINITION | Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2008-05-12 | Deleted | DEFINITION | Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2007-08-09 | Added | SYNONYM | mesoderm cell fate specification |
2007-08-09 | Deleted | SYNONYM | mesoderm cell fate specification |
2005-10-20 | Added | SYNONYM | mesoderm cell fate specification |
2004-05-09 | Updated | DEFINITION | Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
2002-11-27 | Added | DEFINITION | The process involved in the specification of cell identity in the mesoderm. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-11-28 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2013-03-11 | Deleted | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2012-12-21 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2012-10-29 | Added | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2008-04-01 | Updated | RELATION | is a GO:0001708 (cell fate specification) |
2008-04-01 | Updated | RELATION | part of GO:0001710 (mesodermal cell fate commitment) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
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