GO:0007549
JSON
sex-chromosome dosage compensation
Biological Process
Definition (GO:0007549 GONUTS page)
Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes. PMID:11498577 PMID:30049999 PMID:35306885
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
dosage compensation | broad |
sex chromosome dosage compensation | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0007549
Child Term | Relationship to GO:0007549 |
---|---|
dosage compensation by hypoactivation of X chromosome
|
is_a |
dosage compensation complex assembly
|
part_of |
dosage compensation by inactivation of X chromosome
|
is_a |
dosage compensation by hyperactivation of X chromosome
|
is_a |
dosage compensation complex
|
capable_of_part_of |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q90998 | 9031 | Q90998_CHICK | GO:0010468 | 3 NOT-qualified manual annotations exist with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q90999 | 9031 | TGFR2_CHICK | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q96AE4 | 9606 | FUBP1_HUMAN | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:8125259 | |
NOT-qualified manual | protein | Q9USK2 | 284812 | SET9_SCHPO | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243 |
Cross-references
Database | ID | Description |
---|---|---|
Wikipedia | Sex-chromosome_dosage_compensation |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0007550 | obsolete establishment of dosage compensation | consider GO:0007549 |
GO:0007551 | obsolete maintenance of dosage compensation | consider GO:0007549 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0007549 based on ALL annotations
The top 100 of 381 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
sex-chromosome dosage compensation
|
108,936.15 | 100.00 | 1,819 | 1,819 |
chordate embryonic development
|
22,989.88 | 20.02 | 1,449 | 6,866 |
BRCA1-BARD1 complex
|
15,967.91 | 14.13 | 1,451 | 9,899 |
negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
|
56,465.68 | 10.52 | 212 | 409 |
BRCA1-A complex
|
10,707.65 | 9.59 | 1,451 | 14,762 |
Barr body
|
34,400.90 | 7.47 | 162 | 513 |
positive regulation of keratinocyte differentiation
|
15,614.92 | 6.87 | 212 | 1,479 |
negative regulation of protein localization to chromosome, telomeric region
|
108,936.15 | 5.61 | 102 | 102 |
regulation of NAD metabolic process
|
107,813.09 | 5.27 | 96 | 97 |
negative regulation of cell cycle G2/M phase transition
|
47,688.79 | 5.23 | 102 | 233 |
Totals | 16711 | 1053633 |
No co-occurrence statistics for GO:0007549 based on MANUAL annotations
The top 100 of 319 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
sex-chromosome dosage compensation
|
28,230.66 | 100.00 | 50 | 50 |
BRCA1-BARD1 complex
|
9,145.14 | 23.47 | 23 | 71 |
X chromosome located dosage compensation complex, transcription activating
|
21,172.99 | 11.54 | 6 | 8 |
BRCA1-A complex
|
2,751.29 | 8.75 | 23 | 236 |
Barr body
|
5,646.13 | 8.11 | 6 | 30 |
chordate embryonic development
|
2,431.85 | 7.82 | 23 | 267 |
dosage compensation by hyperactivation of X chromosome
|
4,131.32 | 7.06 | 6 | 41 |
X chromosome
|
3,682.26 | 6.67 | 6 | 46 |
regulation of NAD metabolic process
|
21,172.99 | 5.88 | 3 | 4 |
negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
|
2,663.27 | 5.10 | 5 | 53 |
Totals | 339 | 6819 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-06 | Updated | TERM | sex-chromosome dosage compensation |
2023-09-06 | Added | XREF | Wikipedia:Sex-chromosome_dosage_compensation |
2023-09-06 | Added | SYNONYM | dosage compensation |
2023-09-06 | Deleted | XREF | Wikipedia:Dosage_compensation |
2023-09-06 | Added | SYNONYM | sex chromosome dosage compensation |
2017-06-03 | Added | DEFINITION | Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes. |
2017-06-03 | Deleted | DEFINITION | Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. |
2009-03-02 | Added | XREF | Wikipedia:Dosage_compensation |
2008-05-13 | Added | DEFINITION | Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. |
2008-05-12 | Deleted | DEFINITION | Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-06 | Updated | TERM | sex-chromosome dosage compensation |
2002-02-06 | Updated | TERM | dosage compensation |
2001-04-03 | Updated | TERM | dosage compensation |
2001-03-30 | Added | TERM | dosage compensation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-06 | Added | SYNONYM | dosage compensation |
2023-09-06 | Added | SYNONYM | sex chromosome dosage compensation |
2017-06-03 | Added | DEFINITION | Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes. |
2017-06-03 | Deleted | DEFINITION | Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. |
2008-05-13 | Added | DEFINITION | Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. |
2008-05-12 | Deleted | DEFINITION | Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. |
2002-11-27 | Added | DEFINITION | Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0040029 (epigenetic regulation of gene expression) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-06 | Added | XREF | Wikipedia:Sex-chromosome_dosage_compensation |
2023-09-06 | Deleted | XREF | Wikipedia:Dosage_compensation |
2009-03-02 | Added | XREF | Wikipedia:Dosage_compensation |
Timestamp | Action | Category | Detail |
---|
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