This term is obsolete.

GO:0007549 JSON

sex-chromosome dosage compensation

Biological Process

Definition (GO:0007549 GONUTS page)

Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes. PMID:11498577 PMID:30049999 PMID:35306885

4,557 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
dosage compensation broad
sex chromosome dosage compensation exact

Ancestor Chart

Ancestor chart for GO:0007549
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007549

Child Term Relationship to
GO:0007549
dosage compensation by hypoactivation of X chromosome
is_a
dosage compensation complex assembly
part_of
dosage compensation by inactivation of X chromosome
is_a
dosage compensation by hyperactivation of X chromosome
is_a
dosage compensation complex
capable_of_part_of

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P9WNV7 83332 DNAJ2_MYCTU GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487
NOT-qualified manual protein Q90998 9031 Q90998_CHICK GO:0010468 3 NOT-qualified manual annotations exist with evidence code ECO:0000315 from this reference: PMID:11500982
NOT-qualified manual protein Q90999 9031 TGFR2_CHICK GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982
NOT-qualified manual protein Q96AE4 9606 FUBP1_HUMAN GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:8125259
NOT-qualified manual protein Q9USK2 284812 SET9_SCHPO GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243

Cross-references

Database ID Description
Wikipedia Sex-chromosome_dosage_compensation

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0007550 obsolete establishment of dosage compensation consider GO:0007549
GO:0007551 obsolete maintenance of dosage compensation consider GO:0007549

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0007549 based on ALL annotations
The top 100 of 381 co-occurring terms
Co-occurring Term PR S% #Together #Compared
sex-chromosome dosage compensation
108,936.15 100.00 1,819 1,819
chordate embryonic development
22,989.88 20.02 1,449 6,866
BRCA1-BARD1 complex
15,967.91 14.13 1,451 9,899
negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
56,465.68 10.52 212 409
BRCA1-A complex
10,707.65 9.59 1,451 14,762
Barr body
34,400.90 7.47 162 513
positive regulation of keratinocyte differentiation
15,614.92 6.87 212 1,479
negative regulation of protein localization to chromosome, telomeric region
108,936.15 5.61 102 102
regulation of NAD metabolic process
107,813.09 5.27 96 97
negative regulation of cell cycle G2/M phase transition
47,688.79 5.23 102 233
Totals 16711 1053633
No co-occurrence statistics for GO:0007549 based on MANUAL annotations
The top 100 of 319 co-occurring terms
Co-occurring Term PR S% #Together #Compared
sex-chromosome dosage compensation
28,230.66 100.00 50 50
BRCA1-BARD1 complex
9,145.14 23.47 23 71
X chromosome located dosage compensation complex, transcription activating
21,172.99 11.54 6 8
BRCA1-A complex
2,751.29 8.75 23 236
Barr body
5,646.13 8.11 6 30
chordate embryonic development
2,431.85 7.82 23 267
dosage compensation by hyperactivation of X chromosome
4,131.32 7.06 6 41
X chromosome
3,682.26 6.67 6 46
regulation of NAD metabolic process
21,172.99 5.88 3 4
negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
2,663.27 5.10 5 53
Totals 339 6819

Change Log

Timestamp Action Category Detail
2023-09-06 Updated TERM sex-chromosome dosage compensation
2023-09-06 Added XREF Wikipedia:Sex-chromosome_dosage_compensation
2023-09-06 Added SYNONYM dosage compensation
2023-09-06 Deleted XREF Wikipedia:Dosage_compensation
2023-09-06 Added SYNONYM sex chromosome dosage compensation
2017-06-03 Added DEFINITION Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes.
2017-06-03 Deleted DEFINITION Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.
2009-03-02 Added XREF Wikipedia:Dosage_compensation
2008-05-13 Added DEFINITION Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.
2008-05-12 Deleted DEFINITION Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.
Timestamp Action Category Detail
2023-09-06 Updated TERM sex-chromosome dosage compensation
2002-02-06 Updated TERM dosage compensation
2001-04-03 Updated TERM dosage compensation
2001-03-30 Added TERM dosage compensation
Timestamp Action Category Detail
2023-09-06 Added SYNONYM dosage compensation
2023-09-06 Added SYNONYM sex chromosome dosage compensation
2017-06-03 Added DEFINITION Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes.
2017-06-03 Deleted DEFINITION Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.
2008-05-13 Added DEFINITION Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.
2008-05-12 Deleted DEFINITION Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.
2002-11-27 Added DEFINITION Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0040029 (epigenetic regulation of gene expression)
Timestamp Action Category Detail
2023-09-06 Added XREF Wikipedia:Sex-chromosome_dosage_compensation
2023-09-06 Deleted XREF Wikipedia:Dosage_compensation
2009-03-02 Added XREF Wikipedia:Dosage_compensation
Timestamp Action Category Detail
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