This term should only be used in cases when the regulator directly interacts with the enzyme.
GO:0008047
JSON
enzyme activator activity
Molecular Function
Definition (GO:0008047 GONUTS page)
Binds to and increases the activity of an enzyme.
Comments
This term should only be used in cases when the regulator directly interacts with the enzyme.
Secondary IDs
GO:0010577
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
metalloenzyme activator activity | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0008047
Child Term | Relationship to GO:0008047 |
---|---|
ubiquitin-protein transferase activator activity
|
is_a |
enzyme activator complex
|
capable_of |
phosphatase activator activity
|
is_a |
nuclease activator activity
|
is_a |
ornithine decarboxylase activator activity
|
is_a |
superoxide-generating NADPH oxidase activator activity
|
is_a |
peptidase activator activity
|
is_a |
lipase activator activity
|
is_a |
phosphatidylcholine-sterol O-acyltransferase activator activity
|
is_a |
tRNA ligase activator activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000671 | Peptidase A31 family |
InterPro | IPR001446 | 5-lipoxygenase-activating protein |
InterPro | IPR001981 | Colipase |
InterPro | IPR008019 | Apolipoprotein C-II |
InterPro | IPR010334 | mRNA-decapping enzyme subunit 1 |
InterPro | IPR017913 | Colipase, N-terminal |
InterPro | IPR017914 | Colipase, C-terminal |
InterPro | IPR017915 | Colipase, conserved site |
InterPro | IPR018295 | FLAP/GST2/LTC4S, conserved site |
InterPro | IPR028996 | Ganglioside GM2 activator |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0090216 | obsolete positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity | consider GO:0008047 |
GO:1900490 | obsolete positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity | consider GO:0008047 |
GO:1905643 | obsolete positive regulation of DNA methylation | consider GO:0008047 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008047 based on ALL annotations
The top 100 of 2,027 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
enzyme activator activity
|
2,388.67 | 100.00 | 82,956 | 82,956 |
DNA synthesis involved in DNA repair
|
1,020.92 | 31.89 | 46,176 | 108,039 |
single-stranded DNA helicase activity
|
965.89 | 30.56 | 46,110 | 114,031 |
DNA-templated DNA replication
|
242.50 | 9.39 | 46,117 | 454,259 |
deadenylation-independent decapping of nuclear-transcribed mRNA
|
872.43 | 6.17 | 5,736 | 15,705 |
deadenylation-dependent decapping of nuclear-transcribed mRNA
|
549.79 | 5.98 | 6,205 | 26,959 |
protein processing
|
179.87 | 5.95 | 18,338 | 243,527 |
endopeptidase activity
|
155.88 | 5.31 | 18,338 | 281,013 |
P-body
|
108.21 | 2.85 | 5,901 | 130,260 |
DNA replication
|
66.02 | 2.70 | 44,717 | 1,617,907 |
Totals | 576010 | 63764550 |
No co-occurrence statistics for GO:0008047 based on MANUAL annotations
The top 100 of 1,529 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
enzyme activator activity
|
1,845.14 | 100.00 | 765 | 765 |
positive regulation of mitochondrial DNA replication
|
1,728.28 | 35.84 | 281 | 300 |
mitochondrial genome maintenance
|
983.84 | 27.79 | 281 | 527 |
mitochondrial nucleoid
|
844.44 | 25.59 | 281 | 614 |
DNA synthesis involved in DNA repair
|
630.05 | 11.42 | 112 | 328 |
DNA replication
|
178.58 | 8.63 | 340 | 3,513 |
nucleoid
|
1,726.10 | 7.54 | 58 | 62 |
single-stranded DNA binding
|
140.90 | 6.99 | 347 | 4,544 |
single-stranded DNA helicase activity
|
204.60 | 6.68 | 110 | 992 |
execution phase of apoptosis
|
451.68 | 5.16 | 47 | 192 |
Totals | 3804 | 58485 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-24 | Added | RELATION | is a GO:0140677 (molecular function activator activity) |
2023-04-02 | Deleted | RELATION | is a GO:0140677 (molecular function activator activity) |
2022-09-16 | Added | RELATION | is a GO:0140677 (molecular function activator activity) |
2021-10-04 | Deleted | RELATION | is a GO:0140677 (molecular function activator activity) |
2021-07-10 | Added | RELATION | is a GO:0140677 (molecular function activator activity) |
2021-05-15 | Added | RELATION | is a GO:0030234 (enzyme regulator activity) |
2021-05-15 | Deleted | RELATION | is a GO:0003674 (molecular_function) |
2021-02-17 | Deleted | RELATION | is a GO:0030234 (enzyme regulator activity) |
2021-02-17 | Added | RELATION | is a GO:0003674 (molecular_function) |
2020-11-10 | Deleted | RELATION | part of GO:0043085 (positive regulation of catalytic activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | enzyme activator activity |
2002-02-06 | Updated | TERM | enzyme activator |
2001-04-03 | Updated | TERM | enzyme activator |
2001-03-30 | Added | TERM | enzyme activator |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-04-14 | Added | SYNONYM | metalloenzyme activator activity |
2015-07-11 | Added | DEFINITION | Binds to and increases the activity of an enzyme. |
2015-07-11 | Deleted | DEFINITION | Increases the activity of an enzyme. |
2008-05-13 | Added | DEFINITION | Increases the activity of an enzyme. |
2008-05-12 | Deleted | DEFINITION | Increases the activity of an enzyme. |
2003-07-29 | Updated | DEFINITION | Increases the activity of an enzyme. |
2003-06-17 | Added | DEFINITION | Increases the activity of an ezyme. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-24 | Added | RELATION | is a GO:0140677 (molecular function activator activity) |
2023-04-02 | Deleted | RELATION | is a GO:0140677 (molecular function activator activity) |
2022-09-16 | Added | RELATION | is a GO:0140677 (molecular function activator activity) |
2021-10-04 | Deleted | RELATION | is a GO:0140677 (molecular function activator activity) |
2021-07-10 | Added | RELATION | is a GO:0140677 (molecular function activator activity) |
2021-05-15 | Added | RELATION | is a GO:0030234 (enzyme regulator activity) |
2021-05-15 | Deleted | RELATION | is a GO:0003674 (molecular_function) |
2021-02-17 | Deleted | RELATION | is a GO:0030234 (enzyme regulator activity) |
2021-02-17 | Added | RELATION | is a GO:0003674 (molecular_function) |
2020-11-10 | Deleted | RELATION | part of GO:0043085 (positive regulation of catalytic activity) |
2017-05-05 | Deleted | RELATION | regulates GO:0003824 (catalytic activity) |
2017-05-01 | Added | RELATION | positively regulates GO:0003824 (catalytic activity) |
2017-05-01 | Added | RELATION | regulates GO:0003824 (catalytic activity) |
2011-04-24 | Added | RELATION | part of GO:0043085 (positive regulation of catalytic activity) |
2008-04-01 | Updated | RELATION | is a GO:0030234 (enzyme regulator activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:18.02.01.01 |
2019-05-04 | Added | XREF | MIPS_funcat:18.02.01.01 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-04-14 | Added | SECONDARY | GO:0010577 (metalloenzyme activator activity) |
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