GO:0008131
JSON
primary methylamine oxidase activity
Molecular Function
Definition (GO:0008131 GONUTS page)
Catalysis of the reaction: a primary methyl amine + H2O + O2 = an aldehyde + H2O2 + NH4+.
Secondary IDs
GO:0004041, GO:0008122
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
primary-amine:oxygen oxidoreductase (deaminating) activity | exact |
amine oxidase activity | broad |
primary amine oxidase activity | related |
amine oxidase (copper-containing) activity | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0008131
Child Term | Relationship to GO:0008131 |
---|---|
cyclohexylamine oxidase activity
|
is_a |
D-amino-acid oxidase activity
|
is_a |
L-amino-acid oxidase activity
|
is_a |
negative regulation of primary amine oxidase activity
|
negatively_regulates |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 5270 | BI1_MYCMD | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O42890 | 284812 | CAO2_SCHPO | GO:0008131 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18723604 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.4.3.21 | |
InterPro | IPR000269 | Copper amine oxidase |
InterPro | IPR015798 | Copper amine oxidase, catalytic domain |
InterPro | IPR015800 | Copper amine oxidase, N2-terminal |
InterPro | IPR015802 | Copper amine oxidase, N3-terminal |
InterPro | IPR016182 | Copper amine oxidase, N-terminal |
InterPro | IPR036460 | Copper amine oxidase, catalytic domain superfamily |
KEGG_REACTION | R01853 | |
KEGG_REACTION | R02173 | |
KEGG_REACTION | R02613 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:17478 | aldehyde |
has_participant | CHEBI | CHEBI:228804 | primary methyl ammonium ion |
has_participant | CHEBI | CHEBI:16240 | hydrogen peroxide |
has_participant | CHEBI | CHEBI:28938 | ammonium |
has_participant | CHEBI | CHEBI:15379 | dioxygen |
has_participant | CHEBI | CHEBI:15377 | water |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0052593 | obsolete tryptamine:oxygen oxidoreductase (deaminating) activity | replaced_by GO:0008131 |
GO:0052594 | obsolete aminoacetone:oxygen oxidoreductase(deaminating) activity | replaced_by GO:0008131 |
GO:0052596 | obsolete phenethylamine:oxygen oxidoreductase (deaminating) activity | replaced_by GO:0008131 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008131 based on ALL annotations
The top 100 of 537 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
primary methylamine oxidase activity
|
7,701.02 | 100.00 | 25,731 | 25,731 |
amine metabolic process
|
7,240.28 | 77.35 | 20,932 | 22,264 |
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
|
4,419.73 | 35.00 | 12,167 | 21,200 |
aliphatic amine oxidase activity
|
7,701.02 | 16.39 | 4,217 | 4,217 |
response to jasmonic acid
|
3,305.74 | 3.63 | 980 | 2,283 |
copper ion binding
|
274.30 | 3.53 | 20,856 | 585,529 |
quinone binding
|
258.21 | 3.33 | 20,856 | 622,018 |
monoamine oxidase activity
|
2,203.39 | 3.26 | 913 | 3,191 |
diamine oxidase activity
|
7,701.02 | 2.75 | 708 | 708 |
L-amino-acid oxidase activity
|
619.94 | 2.57 | 938 | 11,652 |
Totals | 172208 | 72199178 |
No co-occurrence statistics for GO:0008131 based on MANUAL annotations
The top 100 of 131 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
primary methylamine oxidase activity
|
3,259.89 | 100.00 | 433 | 433 |
amine metabolic process
|
3,003.00 | 73.38 | 339 | 368 |
response to jasmonic acid
|
1,438.19 | 33.73 | 255 | 578 |
copper ion binding
|
538.36 | 16.00 | 362 | 2,192 |
diamine oxidase activity
|
2,514.77 | 6.12 | 27 | 35 |
putrescine metabolic process
|
2,568.40 | 5.91 | 26 | 33 |
monoamine oxidase activity
|
2,794.19 | 4.13 | 18 | 21 |
quinone binding
|
141.73 | 1.43 | 9 | 207 |
putrescine oxidase activity
|
1,778.12 | 1.37 | 6 | 11 |
flavin adenine dinucleotide binding
|
47.72 | 1.33 | 55 | 3,757 |
Totals | 1745 | 100042 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-28 | Deleted | XREF | MetaCyc:AMACETOXID-RXN |
2024-06-28 | Deleted | XREF | KEGG_REACTION:R02529 |
2024-06-28 | Deleted | XREF | RHEA:28186 |
2024-06-28 | Added | DEFINITION | Catalysis of the reaction: a primary methyl amine + H2O + O2 = an aldehyde + H2O2 + NH4+. |
2024-06-28 | Deleted | DEFINITION | Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide. |
2024-06-28 | Added | SYNONYM | primary amine oxidase activity |
2024-06-28 | Updated | TERM | primary methylamine oxidase activity |
2024-01-15 | Added | XREF | KEGG_REACTION:R02173 |
2024-01-15 | Added | XREF | MetaCyc:AMACETOXID-RXN |
2024-01-15 | Added | XREF | MetaCyc:RXN-10817 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-28 | Updated | TERM | primary methylamine oxidase activity |
2010-09-03 | Updated | TERM | primary amine oxidase activity |
2003-03-19 | Updated | TERM | amine oxidase activity |
2002-02-06 | Updated | TERM | amine oxidase |
2001-04-03 | Updated | TERM | amine oxidase |
2001-03-30 | Added | TERM | amine oxidase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-28 | Added | DEFINITION | Catalysis of the reaction: a primary methyl amine + H2O + O2 = an aldehyde + H2O2 + NH4+. |
2024-06-28 | Deleted | DEFINITION | Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide. |
2024-06-28 | Added | SYNONYM | primary amine oxidase activity |
2010-09-03 | Deleted | SYNONYM | spermine oxidase |
2010-09-03 | Deleted | SYNONYM | DAO activity |
2010-09-03 | Deleted | SYNONYM | monoamine oxidase activity |
2010-09-03 | Added | SYNONYM | amine oxidase activity |
2010-09-03 | Added | SYNONYM | primary-amine:oxygen oxidoreductase (deaminating) activity |
2010-09-03 | Deleted | SYNONYM | tyramine oxidase activity |
2010-09-03 | Deleted | SYNONYM | amine oxygen oxidoreductase activity |
2010-09-03 | Deleted | SYNONYM | adrenaline oxidase activity |
2010-09-03 | Deleted | SYNONYM | histamine deaminase |
2010-09-03 | Deleted | SYNONYM | amine oxidase (flavin-containing) activity |
2010-09-03 | Deleted | SYNONYM | semicarbazide-sensitive amine oxidase |
2010-09-03 | Deleted | SYNONYM | serotonin deaminase |
2010-09-03 | Deleted | SYNONYM | histaminase activity |
2010-09-03 | Deleted | SYNONYM | SSAO |
2010-09-03 | Deleted | SYNONYM | histamine oxidase |
2010-09-03 | Added | DEFINITION | Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide. |
2010-09-03 | Deleted | DEFINITION | Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2. |
2010-09-03 | Deleted | SYNONYM | MAO |
2010-09-03 | Deleted | SYNONYM | amine oxidase (pyridoxal containing) |
2010-09-03 | Deleted | SYNONYM | Cu-amine oxidase activity |
2010-09-03 | Deleted | SYNONYM | benzylamine oxidase |
2010-09-03 | Deleted | SYNONYM | amine:oxygen oxidoreductase (deaminating) (flavin-containing) |
2010-09-03 | Deleted | SYNONYM | diamine oxidase activity |
2010-09-03 | Deleted | SYNONYM | adrenalin oxidase |
2010-09-03 | Deleted | SYNONYM | monoamine:O2 oxidoreductase (deaminating) |
2010-09-03 | Deleted | SYNONYM | spermidine oxidase |
2010-09-03 | Deleted | SYNONYM | diamino oxhydrase activity |
2010-09-03 | Deleted | SYNONYM | epinephrine oxidase |
2010-09-03 | Deleted | SYNONYM | tyraminase activity |
2009-02-25 | Deleted | SYNONYM | amine:oxygen oxidoreductase (deaminating) (copper-containing) |
2009-02-25 | Deleted | SYNONYM | diamine:O2 oxidoreductase (deaminating) |
2009-02-25 | Deleted | SYNONYM | diamine oxidase activity |
2009-02-25 | Added | SYNONYM | Cu-amine oxidase activity |
2009-02-25 | Deleted | SYNONYM | Cu-amine oxidase activity |
2009-02-25 | Added | SYNONYM | diamine oxidase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2. |
2007-11-08 | Added | SYNONYM | serotonin deaminase |
2007-11-08 | Deleted | SYNONYM | diamino oxhydrase activity |
2007-11-08 | Added | SYNONYM | spermidine oxidase |
2007-11-08 | Added | SYNONYM | spermine oxidase |
2007-11-08 | Added | SYNONYM | Cu-amine oxidase activity |
2007-11-08 | Added | SYNONYM | MAO |
2007-11-08 | Added | SYNONYM | SSAO |
2007-11-08 | Added | SYNONYM | adrenalin oxidase |
2007-11-08 | Added | SYNONYM | amine oxidase (pyridoxal containing) |
2007-11-08 | Added | SYNONYM | amine oxygen oxidoreductase activity |
2007-11-08 | Added | SYNONYM | amine:oxygen oxidoreductase (deaminating) (copper-containing) |
2007-11-08 | Added | SYNONYM | amine:oxygen oxidoreductase (deaminating) (flavin-containing) |
2007-11-08 | Added | SYNONYM | benzylamine oxidase |
2007-11-08 | Added | SYNONYM | diamine:O2 oxidoreductase (deaminating) |
2007-11-08 | Added | SYNONYM | diamino oxhydrase activity |
2007-11-08 | Added | SYNONYM | epinephrine oxidase |
2007-11-08 | Added | SYNONYM | histamine deaminase |
2007-11-08 | Added | SYNONYM | histamine oxidase |
2007-11-08 | Added | SYNONYM | monoamine:O2 oxidoreductase (deaminating) |
2007-11-08 | Added | SYNONYM | semicarbazide-sensitive amine oxidase |
2007-10-13 | Deleted | SYNONYM | amine oxidase activity |
2007-09-06 | Added | SYNONYM | amine oxidase activity |
2007-09-06 | Added | SYNONYM | diamino oxhydrase activity |
2007-09-06 | Added | SYNONYM | diamine oxidase activity |
2007-09-06 | Added | SYNONYM | tyraminase activity |
2007-09-06 | Added | SYNONYM | tyramine oxidase activity |
2007-09-06 | Added | SYNONYM | monoamine oxidase activity |
2007-09-06 | Added | SYNONYM | histaminase activity |
2007-09-06 | Added | SYNONYM | DAO activity |
2007-09-06 | Added | SYNONYM | adrenaline oxidase activity |
2007-08-09 | Deleted | SYNONYM | amine oxidase (flavin-containing) activity |
2007-08-09 | Deleted | SYNONYM | amine oxidase (copper-containing) activity |
2007-08-09 | Added | SYNONYM | amine oxidase (flavin-containing) activity |
2007-08-09 | Added | SYNONYM | amine oxidase (copper-containing) activity |
2004-04-30 | Added | SYNONYM | amine oxidase (flavin-containing) activity |
2004-04-30 | Added | SYNONYM | amine oxidase (copper-containing) activity |
2004-04-30 | Added | DEFINITION | Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016641 (oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-28 | Deleted | XREF | MetaCyc:AMACETOXID-RXN |
2024-06-28 | Deleted | XREF | KEGG_REACTION:R02529 |
2024-06-28 | Deleted | XREF | RHEA:28186 |
2024-01-15 | Added | XREF | KEGG_REACTION:R02173 |
2024-01-15 | Added | XREF | MetaCyc:AMACETOXID-RXN |
2024-01-15 | Added | XREF | MetaCyc:RXN-10817 |
2024-01-15 | Added | XREF | MetaCyc:RXN-1401 |
2024-01-15 | Added | XREF | RHEA:28186 |
2024-01-15 | Added | XREF | RHEA:16153 |
2024-01-15 | Added | XREF | KEGG_REACTION:R02613 |
2024-01-15 | Added | XREF | KEGG_REACTION:R02529 |
2019-06-20 | Deleted | XREF | KEGG:R01853 |
2019-06-20 | Added | XREF | KEGG_REACTION:R01853 |
2019-05-04 | Added | XREF | Reactome:R-HSA-5603108 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5603108 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5603108 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5603108 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5603108 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5603108 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-379382 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-141186 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-141200 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-379395 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5696183 |
2019-04-01 | Added | XREF | Reactome:R-HSA-141202 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-141202 |
2019-04-01 | Added | XREF | Reactome:R-HSA-379395 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5603108 |
2019-04-01 | Added | XREF | Reactome:R-HSA-374909 |
2019-04-01 | Added | XREF | Reactome:R-HSA-141186 |
2019-04-01 | Added | XREF | Reactome:R-HSA-141200 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5696146 |
2019-04-01 | Added | XREF | Reactome:R-HSA-379382 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-374909 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5696146 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5696183 |
2018-12-11 | Added | XREF | reactome:R-HSA-141200 |
2018-12-11 | Added | XREF | reactome:R-HSA-141202 |
2018-12-11 | Added | XREF | reactome:R-HSA-5696146 |
2018-12-11 | Added | XREF | reactome:R-HSA-379382 |
2018-12-11 | Added | XREF | reactome:R-HSA-141186 |
2018-12-11 | Added | XREF | reactome:R-HSA-5696183 |
2018-12-11 | Added | XREF | reactome:R-HSA-374909 |
2018-12-11 | Added | XREF | reactome:R-HSA-379395 |
2010-09-03 | Deleted | XREF | EC:1.4.3.4 |
2010-09-03 | Deleted | XREF | MetaCyc:AMINEOXID-RXN |
2010-09-03 | Deleted | XREF | EC:1.4.3.22 |
2010-09-03 | Added | XREF | MetaCyc:RXN-9597 |
2010-09-03 | Added | XREF | KEGG:R01853 |
2009-05-21 | Deleted | XREF | MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN |
2009-02-25 | Added | XREF | EC:1.4.3.22 |
2009-02-25 | Added | XREF | EC:1.4.3.21 |
2009-02-25 | Deleted | XREF | EC:1.4.3.6 |
2004-12-03 | Deleted | XREF | MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN "" |
2004-12-03 | Deleted | XREF | EC:1.4.3.6 "" |
2004-12-03 | Deleted | XREF | EC:1.4.3.4 "" |
2004-12-03 | Added | XREF | MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN |
2004-12-03 | Added | XREF | EC:1.4.3.6 |
2004-12-03 | Added | XREF | EC:1.4.3.4 |
2004-04-30 | Added | XREF | MetaCyc:AMINEOXID-RXN |
2004-04-30 | Added | XREF | MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN "" |
2004-04-30 | Added | XREF | EC:1.4.3.6 "" |
2004-04-30 | Deleted | XREF | EC:1.4.3.- |
2004-04-30 | Added | XREF | EC:1.4.3.4 "" |
2001-03-30 | Added | XREF | EC:1.4.3.- |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-04-30 | Added | SECONDARY | GO:0004041 (amine oxidase (flavin-containing) activity) |
2004-04-30 | Added | SECONDARY | GO:0008122 (amine oxidase (copper-containing) activity) |
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link