This term is obsolete.

GO:0008131 JSON

primary methylamine oxidase activity

Molecular Function

Definition (GO:0008131 GONUTS page)

Catalysis of the reaction: a primary methyl amine + H2O + O2 = an aldehyde + H2O2 + NH4+.

Secondary IDs

GO:0004041, GO:0008122

91,973 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
primary-amine:oxygen oxidoreductase (deaminating) activity exact
amine oxidase activity broad
primary amine oxidase activity related
amine oxidase (copper-containing) activity narrow

Ancestor Chart

Ancestor chart for GO:0008131
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008131

Child Term Relationship to
GO:0008131
cyclohexylamine oxidase activity
is_a
D-amino-acid oxidase activity
is_a
L-amino-acid oxidase activity
is_a
negative regulation of primary amine oxidase activity
negatively_regulates

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 5270 BI1_MYCMD GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O42890 284812 CAO2_SCHPO GO:0008131 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18723604

Cross-references

Database ID Description
EC 1.4.3.21
InterPro IPR000269 Copper amine oxidase
InterPro IPR015798 Copper amine oxidase, catalytic domain
InterPro IPR015800 Copper amine oxidase, N2-terminal
InterPro IPR015802 Copper amine oxidase, N3-terminal
InterPro IPR016182 Copper amine oxidase, N-terminal
InterPro IPR036460 Copper amine oxidase, catalytic domain superfamily
KEGG_REACTION R01853
KEGG_REACTION R02173
KEGG_REACTION R02613

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:17478 aldehyde
has_participant CHEBI CHEBI:228804 primary methyl ammonium ion
has_participant CHEBI CHEBI:16240 hydrogen peroxide
has_participant CHEBI CHEBI:28938 ammonium
has_participant CHEBI CHEBI:15379 dioxygen
has_participant CHEBI CHEBI:15377 water

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0052593 obsolete tryptamine:oxygen oxidoreductase (deaminating) activity replaced_by GO:0008131
GO:0052594 obsolete aminoacetone:oxygen oxidoreductase(deaminating) activity replaced_by GO:0008131
GO:0052596 obsolete phenethylamine:oxygen oxidoreductase (deaminating) activity replaced_by GO:0008131

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008131 based on ALL annotations
The top 100 of 537 co-occurring terms
Co-occurring Term PR S% #Together #Compared
primary methylamine oxidase activity
7,701.02 100.00 25,731 25,731
amine metabolic process
7,240.28 77.35 20,932 22,264
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
4,419.73 35.00 12,167 21,200
aliphatic amine oxidase activity
7,701.02 16.39 4,217 4,217
response to jasmonic acid
3,305.74 3.63 980 2,283
copper ion binding
274.30 3.53 20,856 585,529
quinone binding
258.21 3.33 20,856 622,018
monoamine oxidase activity
2,203.39 3.26 913 3,191
diamine oxidase activity
7,701.02 2.75 708 708
L-amino-acid oxidase activity
619.94 2.57 938 11,652
Totals 172208 72199178
No co-occurrence statistics for GO:0008131 based on MANUAL annotations
The top 100 of 131 co-occurring terms
Co-occurring Term PR S% #Together #Compared
primary methylamine oxidase activity
3,259.89 100.00 433 433
amine metabolic process
3,003.00 73.38 339 368
response to jasmonic acid
1,438.19 33.73 255 578
copper ion binding
538.36 16.00 362 2,192
diamine oxidase activity
2,514.77 6.12 27 35
putrescine metabolic process
2,568.40 5.91 26 33
monoamine oxidase activity
2,794.19 4.13 18 21
quinone binding
141.73 1.43 9 207
putrescine oxidase activity
1,778.12 1.37 6 11
flavin adenine dinucleotide binding
47.72 1.33 55 3,757
Totals 1745 100042

Change Log

Timestamp Action Category Detail
2024-06-28 Deleted XREF MetaCyc:AMACETOXID-RXN
2024-06-28 Deleted XREF KEGG_REACTION:R02529
2024-06-28 Deleted XREF RHEA:28186
2024-06-28 Added DEFINITION Catalysis of the reaction: a primary methyl amine + H2O + O2 = an aldehyde + H2O2 + NH4+.
2024-06-28 Deleted DEFINITION Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
2024-06-28 Added SYNONYM primary amine oxidase activity
2024-06-28 Updated TERM primary methylamine oxidase activity
2024-01-15 Added XREF KEGG_REACTION:R02173
2024-01-15 Added XREF MetaCyc:AMACETOXID-RXN
2024-01-15 Added XREF MetaCyc:RXN-10817
Timestamp Action Category Detail
2024-06-28 Updated TERM primary methylamine oxidase activity
2010-09-03 Updated TERM primary amine oxidase activity
2003-03-19 Updated TERM amine oxidase activity
2002-02-06 Updated TERM amine oxidase
2001-04-03 Updated TERM amine oxidase
2001-03-30 Added TERM amine oxidase
Timestamp Action Category Detail
2024-06-28 Added DEFINITION Catalysis of the reaction: a primary methyl amine + H2O + O2 = an aldehyde + H2O2 + NH4+.
2024-06-28 Deleted DEFINITION Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
2024-06-28 Added SYNONYM primary amine oxidase activity
2010-09-03 Deleted SYNONYM spermine oxidase
2010-09-03 Deleted SYNONYM DAO activity
2010-09-03 Deleted SYNONYM monoamine oxidase activity
2010-09-03 Added SYNONYM amine oxidase activity
2010-09-03 Added SYNONYM primary-amine:oxygen oxidoreductase (deaminating) activity
2010-09-03 Deleted SYNONYM tyramine oxidase activity
2010-09-03 Deleted SYNONYM amine oxygen oxidoreductase activity
2010-09-03 Deleted SYNONYM adrenaline oxidase activity
2010-09-03 Deleted SYNONYM histamine deaminase
2010-09-03 Deleted SYNONYM amine oxidase (flavin-containing) activity
2010-09-03 Deleted SYNONYM semicarbazide-sensitive amine oxidase
2010-09-03 Deleted SYNONYM serotonin deaminase
2010-09-03 Deleted SYNONYM histaminase activity
2010-09-03 Deleted SYNONYM SSAO
2010-09-03 Deleted SYNONYM histamine oxidase
2010-09-03 Added DEFINITION Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
2010-09-03 Deleted DEFINITION Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2.
2010-09-03 Deleted SYNONYM MAO
2010-09-03 Deleted SYNONYM amine oxidase (pyridoxal containing)
2010-09-03 Deleted SYNONYM Cu-amine oxidase activity
2010-09-03 Deleted SYNONYM benzylamine oxidase
2010-09-03 Deleted SYNONYM amine:oxygen oxidoreductase (deaminating) (flavin-containing)
2010-09-03 Deleted SYNONYM diamine oxidase activity
2010-09-03 Deleted SYNONYM adrenalin oxidase
2010-09-03 Deleted SYNONYM monoamine:O2 oxidoreductase (deaminating)
2010-09-03 Deleted SYNONYM spermidine oxidase
2010-09-03 Deleted SYNONYM diamino oxhydrase activity
2010-09-03 Deleted SYNONYM epinephrine oxidase
2010-09-03 Deleted SYNONYM tyraminase activity
2009-02-25 Deleted SYNONYM amine:oxygen oxidoreductase (deaminating) (copper-containing)
2009-02-25 Deleted SYNONYM diamine:O2 oxidoreductase (deaminating)
2009-02-25 Deleted SYNONYM diamine oxidase activity
2009-02-25 Added SYNONYM Cu-amine oxidase activity
2009-02-25 Deleted SYNONYM Cu-amine oxidase activity
2009-02-25 Added SYNONYM diamine oxidase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2.
2007-11-08 Added SYNONYM serotonin deaminase
2007-11-08 Deleted SYNONYM diamino oxhydrase activity
2007-11-08 Added SYNONYM spermidine oxidase
2007-11-08 Added SYNONYM spermine oxidase
2007-11-08 Added SYNONYM Cu-amine oxidase activity
2007-11-08 Added SYNONYM MAO
2007-11-08 Added SYNONYM SSAO
2007-11-08 Added SYNONYM adrenalin oxidase
2007-11-08 Added SYNONYM amine oxidase (pyridoxal containing)
2007-11-08 Added SYNONYM amine oxygen oxidoreductase activity
2007-11-08 Added SYNONYM amine:oxygen oxidoreductase (deaminating) (copper-containing)
2007-11-08 Added SYNONYM amine:oxygen oxidoreductase (deaminating) (flavin-containing)
2007-11-08 Added SYNONYM benzylamine oxidase
2007-11-08 Added SYNONYM diamine:O2 oxidoreductase (deaminating)
2007-11-08 Added SYNONYM diamino oxhydrase activity
2007-11-08 Added SYNONYM epinephrine oxidase
2007-11-08 Added SYNONYM histamine deaminase
2007-11-08 Added SYNONYM histamine oxidase
2007-11-08 Added SYNONYM monoamine:O2 oxidoreductase (deaminating)
2007-11-08 Added SYNONYM semicarbazide-sensitive amine oxidase
2007-10-13 Deleted SYNONYM amine oxidase activity
2007-09-06 Added SYNONYM amine oxidase activity
2007-09-06 Added SYNONYM diamino oxhydrase activity
2007-09-06 Added SYNONYM diamine oxidase activity
2007-09-06 Added SYNONYM tyraminase activity
2007-09-06 Added SYNONYM tyramine oxidase activity
2007-09-06 Added SYNONYM monoamine oxidase activity
2007-09-06 Added SYNONYM histaminase activity
2007-09-06 Added SYNONYM DAO activity
2007-09-06 Added SYNONYM adrenaline oxidase activity
2007-08-09 Deleted SYNONYM amine oxidase (flavin-containing) activity
2007-08-09 Deleted SYNONYM amine oxidase (copper-containing) activity
2007-08-09 Added SYNONYM amine oxidase (flavin-containing) activity
2007-08-09 Added SYNONYM amine oxidase (copper-containing) activity
2004-04-30 Added SYNONYM amine oxidase (flavin-containing) activity
2004-04-30 Added SYNONYM amine oxidase (copper-containing) activity
2004-04-30 Added DEFINITION Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016641 (oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor)
Timestamp Action Category Detail
2024-06-28 Deleted XREF MetaCyc:AMACETOXID-RXN
2024-06-28 Deleted XREF KEGG_REACTION:R02529
2024-06-28 Deleted XREF RHEA:28186
2024-01-15 Added XREF KEGG_REACTION:R02173
2024-01-15 Added XREF MetaCyc:AMACETOXID-RXN
2024-01-15 Added XREF MetaCyc:RXN-10817
2024-01-15 Added XREF MetaCyc:RXN-1401
2024-01-15 Added XREF RHEA:28186
2024-01-15 Added XREF RHEA:16153
2024-01-15 Added XREF KEGG_REACTION:R02613
2024-01-15 Added XREF KEGG_REACTION:R02529
2019-06-20 Deleted XREF KEGG:R01853
2019-06-20 Added XREF KEGG_REACTION:R01853
2019-05-04 Added XREF Reactome:R-HSA-5603108
2019-04-30 Deleted XREF Reactome:R-HSA-5603108
2019-04-29 Added XREF Reactome:R-HSA-5603108
2019-04-28 Deleted XREF Reactome:R-HSA-5603108
2019-04-27 Added XREF Reactome:R-HSA-5603108
2019-04-23 Deleted XREF Reactome:R-HSA-5603108
2019-04-01 Deleted XREF reactome:R-HSA-379382
2019-04-01 Deleted XREF reactome:R-HSA-141186
2019-04-01 Deleted XREF reactome:R-HSA-141200
2019-04-01 Deleted XREF reactome:R-HSA-379395
2019-04-01 Added XREF Reactome:R-HSA-5696183
2019-04-01 Added XREF Reactome:R-HSA-141202
2019-04-01 Deleted XREF reactome:R-HSA-141202
2019-04-01 Added XREF Reactome:R-HSA-379395
2019-04-01 Added XREF Reactome:R-HSA-5603108
2019-04-01 Added XREF Reactome:R-HSA-374909
2019-04-01 Added XREF Reactome:R-HSA-141186
2019-04-01 Added XREF Reactome:R-HSA-141200
2019-04-01 Added XREF Reactome:R-HSA-5696146
2019-04-01 Added XREF Reactome:R-HSA-379382
2019-04-01 Deleted XREF reactome:R-HSA-374909
2019-04-01 Deleted XREF reactome:R-HSA-5696146
2019-04-01 Deleted XREF reactome:R-HSA-5696183
2018-12-11 Added XREF reactome:R-HSA-141200
2018-12-11 Added XREF reactome:R-HSA-141202
2018-12-11 Added XREF reactome:R-HSA-5696146
2018-12-11 Added XREF reactome:R-HSA-379382
2018-12-11 Added XREF reactome:R-HSA-141186
2018-12-11 Added XREF reactome:R-HSA-5696183
2018-12-11 Added XREF reactome:R-HSA-374909
2018-12-11 Added XREF reactome:R-HSA-379395
2010-09-03 Deleted XREF EC:1.4.3.4
2010-09-03 Deleted XREF MetaCyc:AMINEOXID-RXN
2010-09-03 Deleted XREF EC:1.4.3.22
2010-09-03 Added XREF MetaCyc:RXN-9597
2010-09-03 Added XREF KEGG:R01853
2009-05-21 Deleted XREF MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN
2009-02-25 Added XREF EC:1.4.3.22
2009-02-25 Added XREF EC:1.4.3.21
2009-02-25 Deleted XREF EC:1.4.3.6
2004-12-03 Deleted XREF MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN ""
2004-12-03 Deleted XREF EC:1.4.3.6 ""
2004-12-03 Deleted XREF EC:1.4.3.4 ""
2004-12-03 Added XREF MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN
2004-12-03 Added XREF EC:1.4.3.6
2004-12-03 Added XREF EC:1.4.3.4
2004-04-30 Added XREF MetaCyc:AMINEOXID-RXN
2004-04-30 Added XREF MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN ""
2004-04-30 Added XREF EC:1.4.3.6 ""
2004-04-30 Deleted XREF EC:1.4.3.-
2004-04-30 Added XREF EC:1.4.3.4 ""
2001-03-30 Added XREF EC:1.4.3.-
Timestamp Action Category Detail
2004-04-30 Added SECONDARY GO:0004041 (amine oxidase (flavin-containing) activity)
2004-04-30 Added SECONDARY GO:0008122 (amine oxidase (copper-containing) activity)
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