GO:0008177
JSON
succinate dehydrogenase (quinone) activity
Molecular Function
Definition (GO:0008177 GONUTS page)
Catalysis of the reaction: a quinone + succinate = a quinol + fumarate.
Secondary IDs
GO:0019737
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
succinic dehydrogenase activity | broad |
succinate dehydrogenase (ubiquinone) activity | narrow |
fumarate reductase (menaquinone) | narrow |
succinate dehydrogenase (menaquinone) | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0008177
Child Term | Relationship to GO:0008177 |
---|---|
respiratory chain complex II (succinate dehydrogenase)
|
capable_of |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.3.5.1 | |
KEGG_REACTION | R02164 | |
MetaCyc | RXN-14971 | |
RHEA | 40523 | |
Reactome | R-HSA-163213 | |
Reactome | R-HSA-70994 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:132124 | 1,4-benzoquinones |
has_participant | CHEBI | CHEBI:30031 | succinate(2-) |
has_participant | CHEBI | CHEBI:29806 | fumarate(2-) |
has_participant | CHEBI | CHEBI:24646 | hydroquinones |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0102040 | obsolete fumarate reductase (menaquinone) | replaced_by GO:0008177 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008177 based on ALL annotations
The top 100 of 308 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
succinate dehydrogenase (quinone) activity
|
5,117.58 | 100.00 | 38,092 | 38,092 |
succinate dehydrogenase activity
|
1,490.95 | 19.05 | 13,519 | 46,403 |
mitochondrial electron transport, succinate to ubiquinone
|
1,671.26 | 12.14 | 6,167 | 18,884 |
3 iron, 4 sulfur cluster binding
|
600.57 | 9.64 | 13,363 | 113,869 |
anaerobic respiration
|
497.92 | 8.36 | 14,206 | 146,007 |
electron transport chain
|
319.53 | 5.88 | 19,016 | 304,562 |
oxidoreductase activity, acting on the CH-CH group of donors
|
249.72 | 4.65 | 19,036 | 390,105 |
tricarboxylic acid cycle
|
238.61 | 4.62 | 31,934 | 684,903 |
respiratory chain complex II (succinate dehydrogenase)
|
1,332.95 | 2.89 | 1,201 | 4,611 |
electron transfer activity
|
122.27 | 2.39 | 37,019 | 1,549,364 |
Totals | 373178 | 142721120 |
No co-occurrence statistics for GO:0008177 based on MANUAL annotations
The top 52 of 52 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
succinate dehydrogenase (quinone) activity
|
7,216.75 | 100.00 | 179 | 179 |
respiratory chain complex II (succinate dehydrogenase)
|
2,915.50 | 38.76 | 162 | 401 |
mitochondrial electron transport, succinate to ubiquinone
|
2,483.18 | 33.06 | 160 | 465 |
electron transfer activity
|
621.28 | 8.39 | 138 | 1,603 |
3 iron, 4 sulfur cluster binding
|
1,890.10 | 5.24 | 11 | 42 |
ubiquinone binding
|
454.39 | 3.94 | 17 | 270 |
flavin adenine dinucleotide binding
|
284.19 | 3.89 | 137 | 3,479 |
succinate metabolic process
|
648.70 | 3.08 | 8 | 89 |
respiratory electron transport chain
|
185.04 | 2.09 | 18 | 702 |
proton motive force-driven mitochondrial ATP synthesis
|
130.23 | 1.44 | 12 | 665 |
Totals | 1045 | 677565 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-16 | Added | RELATION | is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor) |
2023-12-15 | Added | SYNONYM | succinate dehydrogenase (ubiquinone) activity |
2023-12-15 | Deleted | XREF | MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN |
2023-12-15 | Added | DEFINITION | Catalysis of the reaction: a quinone + succinate = a quinol + fumarate. |
2023-12-15 | Deleted | DEFINITION | Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol. |
2023-12-15 | Deleted | XREF | RHEA:13713 |
2023-12-15 | Updated | TERM | succinate dehydrogenase (quinone) activity |
2023-12-15 | Added | XREF | RHEA:40523 |
2023-12-15 | Added | XREF | MetaCyc:RXN-14971 |
2023-12-15 | Added | SYNONYM | succinate dehydrogenase (menaquinone) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-15 | Updated | TERM | succinate dehydrogenase (quinone) activity |
2003-03-19 | Updated | TERM | succinate dehydrogenase (ubiquinone) activity |
2002-10-24 | Updated | TERM | succinate dehydrogenase (ubiquinone) |
2002-02-06 | Updated | TERM | succinate dehydrogenase-(ubiquinone) |
2001-04-03 | Updated | TERM | succinate dehydrogenase-(ubiquinone) |
2001-03-30 | Added | TERM | succinate dehydrogenase-(ubiquinone) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-15 | Added | SYNONYM | succinate dehydrogenase (ubiquinone) activity |
2023-12-15 | Added | DEFINITION | Catalysis of the reaction: a quinone + succinate = a quinol + fumarate. |
2023-12-15 | Deleted | DEFINITION | Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol. |
2023-12-15 | Added | SYNONYM | succinate dehydrogenase (menaquinone) |
2023-12-15 | Added | SYNONYM | fumarate reductase (menaquinone) |
2023-12-15 | Deleted | SYNONYM | succinate:ubiquinone oxidoreductase activity |
2023-09-06 | Deleted | SYNONYM | succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration) |
2023-09-06 | Deleted | SYNONYM | quinol:fumarate oxidoreductase activity |
2023-09-06 | Deleted | SYNONYM | menaquinol: fumarate oxidoreductase activity |
2023-09-06 | Deleted | SYNONYM | respiratory complex II |
2023-09-06 | Deleted | SYNONYM | fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration) |
2021-01-04 | Deleted | SYNONYM | complex II |
2021-01-04 | Added | SYNONYM | respiratory complex II |
2020-10-08 | Deleted | SYNONYM | menaquinol: fumarate oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | succinate:ubiquinone oxidoreductase activity |
2020-10-08 | Added | SYNONYM | menaquinol: fumarate oxidoreductase activity |
2020-10-08 | Added | SYNONYM | succinate:ubiquinone oxidoreductase activity |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: succinate + quinone = fumarate + quinol. |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: succinate + quinone = fumarate + quinol. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: succinate + quinone = fumarate + quinol. |
2007-11-08 | Added | SYNONYM | succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration) |
2007-11-08 | Added | SYNONYM | menaquinol: fumarate oxidoreductase activity |
2007-11-08 | Added | SYNONYM | fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration) |
2007-11-08 | Added | SYNONYM | complex II |
2007-11-08 | Added | SYNONYM | succinate:ubiquinone oxidoreductase activity |
2007-09-06 | Added | SYNONYM | succinic dehydrogenase activity |
2007-08-09 | Added | SYNONYM | quinol:fumarate oxidoreductase activity |
2007-08-09 | Deleted | SYNONYM | quinol:fumarate oxidoreductase activity |
2004-04-19 | Added | SYNONYM | quinol:fumarate oxidoreductase activity |
2004-04-16 | Deleted | SYNONYM | quinol:fumarate oxidoreductase activity |
2003-12-16 | Added | SYNONYM | quinol:fumarate oxidoreductase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: succinate + quinone = fumarate + quinol. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-16 | Added | RELATION | is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor) |
2023-09-06 | Deleted | RELATION | is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor) |
2009-11-24 | Added | RELATION | is a GO:0000104 (succinate dehydrogenase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-15 | Deleted | XREF | MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN |
2023-12-15 | Deleted | XREF | RHEA:13713 |
2023-12-15 | Added | XREF | RHEA:40523 |
2023-12-15 | Added | XREF | MetaCyc:RXN-14971 |
2019-06-20 | Deleted | XREF | KEGG:R02164 |
2019-06-20 | Added | XREF | KEGG_REACTION:R02164 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-163213 |
2019-04-01 | Added | XREF | Reactome:R-HSA-70994 |
2019-04-01 | Added | XREF | Reactome:R-HSA-163213 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-70994 |
2018-12-11 | Added | XREF | reactome:R-HSA-163213 |
2018-12-11 | Added | XREF | reactome:R-HSA-70994 |
2018-07-13 | Deleted | XREF | RHEA:13716 |
2018-07-13 | Added | XREF | RHEA:13713 |
2010-10-11 | Added | XREF | KEGG:R02164 |
2010-10-11 | Added | XREF | RHEA:13716 |
2009-05-21 | Added | XREF | MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN |
2001-03-30 | Added | XREF | EC:1.3.5.1 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-12-16 | Added | SECONDARY | GO:0019737 (quinol:fumarate oxidoreductase activity) |
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