This term is obsolete.

GO:0008177 JSON

succinate dehydrogenase (quinone) activity

Molecular Function

Definition (GO:0008177 GONUTS page)

Catalysis of the reaction: a quinone + succinate = a quinol + fumarate.

Secondary IDs

GO:0019737

37,887 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
succinic dehydrogenase activity broad
succinate dehydrogenase (ubiquinone) activity narrow
fumarate reductase (menaquinone) narrow
succinate dehydrogenase (menaquinone) narrow

Ancestor Chart

Ancestor chart for GO:0008177
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008177

Child Term Relationship to
GO:0008177
respiratory chain complex II (succinate dehydrogenase)
capable_of

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 5270 BI1_MYCMD GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884

Cross-references

Database ID Description
EC 1.3.5.1
KEGG_REACTION R02164
MetaCyc RXN-14971
RHEA 40523
Reactome R-HSA-163213
Reactome R-HSA-70994

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:132124 1,4-benzoquinones
has_participant CHEBI CHEBI:30031 succinate(2-)
has_participant CHEBI CHEBI:29806 fumarate(2-)
has_participant CHEBI CHEBI:24646 hydroquinones

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0102040 obsolete fumarate reductase (menaquinone) replaced_by GO:0008177

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008177 based on ALL annotations
The top 100 of 307 co-occurring terms
Co-occurring Term PR S% #Together #Compared
succinate dehydrogenase (quinone) activity
5,256.38 100.00 37,698 37,698
succinate dehydrogenase activity
1,479.46 18.58 13,319 47,321
mitochondrial electron transport, succinate to ubiquinone
1,725.18 12.60 6,402 19,506
3 iron, 4 sulfur cluster binding
557.04 8.81 12,928 121,992
anaerobic respiration
495.00 8.12 14,003 148,697
electron transport chain
324.19 5.82 19,059 309,017
steroid dehydrogenase activity, acting on the CH-CH group of donors
652.54 5.62 3,508 28,258
tricarboxylic acid cycle
235.45 4.44 31,557 704,515
oxidoreductase activity, acting on the CH-CH group of donors
206.39 3.78 19,079 485,901
respiratory chain complex II (succinate dehydrogenase)
1,024.31 2.83 1,208 6,199
Totals 371110 141656826
No co-occurrence statistics for GO:0008177 based on MANUAL annotations
The top 51 of 51 co-occurring terms
Co-occurring Term PR S% #Together #Compared
succinate dehydrogenase (quinone) activity
7,390.23 100.00 191 191
respiratory chain complex II (succinate dehydrogenase)
3,024.84 39.55 176 430
mitochondrial electron transport, succinate to ubiquinone
2,572.45 33.59 173 497
electron transfer activity
654.23 8.66 152 1,717
3 iron, 4 sulfur cluster binding
1,847.56 4.91 11 44
flavin adenine dinucleotide binding
297.03 3.98 151 3,757
ubiquinone binding
486.95 3.94 17 258
succinate metabolic process
649.69 2.92 8 91
respiratory electron transport chain
196.66 2.14 19 714
proton motive force-driven mitochondrial ATP synthesis
125.79 1.36 12 705
Totals 1114 714294

Change Log

Timestamp Action Category Detail
2024-05-16 Added RELATION is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor)
2023-12-15 Deleted DEFINITION Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
2023-12-15 Added XREF MetaCyc:RXN-14971
2023-12-15 Added XREF RHEA:40523
2023-12-15 Deleted XREF MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN
2023-12-15 Deleted XREF RHEA:13713
2023-12-15 Updated TERM succinate dehydrogenase (quinone) activity
2023-12-15 Added SYNONYM succinate dehydrogenase (ubiquinone) activity
2023-12-15 Deleted SYNONYM succinate:ubiquinone oxidoreductase activity
2023-12-15 Added SYNONYM succinate dehydrogenase (menaquinone)
Timestamp Action Category Detail
2023-12-15 Updated TERM succinate dehydrogenase (quinone) activity
2003-03-19 Updated TERM succinate dehydrogenase (ubiquinone) activity
2002-10-24 Updated TERM succinate dehydrogenase (ubiquinone)
2002-02-06 Updated TERM succinate dehydrogenase-(ubiquinone)
2001-04-03 Updated TERM succinate dehydrogenase-(ubiquinone)
2001-03-30 Added TERM succinate dehydrogenase-(ubiquinone)
Timestamp Action Category Detail
2023-12-15 Deleted DEFINITION Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
2023-12-15 Added SYNONYM succinate dehydrogenase (ubiquinone) activity
2023-12-15 Deleted SYNONYM succinate:ubiquinone oxidoreductase activity
2023-12-15 Added SYNONYM succinate dehydrogenase (menaquinone)
2023-12-15 Added SYNONYM fumarate reductase (menaquinone)
2023-12-15 Added DEFINITION Catalysis of the reaction: a quinone + succinate = a quinol + fumarate.
2023-09-06 Deleted SYNONYM respiratory complex II
2023-09-06 Deleted SYNONYM menaquinol: fumarate oxidoreductase activity
2023-09-06 Deleted SYNONYM quinol:fumarate oxidoreductase activity
2023-09-06 Deleted SYNONYM succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)
2023-09-06 Deleted SYNONYM fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)
2021-01-04 Deleted SYNONYM complex II
2021-01-04 Added SYNONYM respiratory complex II
2020-10-08 Deleted SYNONYM menaquinol: fumarate oxidoreductase activity
2020-10-08 Deleted SYNONYM succinate:ubiquinone oxidoreductase activity
2020-10-08 Added SYNONYM succinate:ubiquinone oxidoreductase activity
2020-10-08 Added SYNONYM menaquinol: fumarate oxidoreductase activity
2010-10-11 Added DEFINITION Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: succinate + quinone = fumarate + quinol.
2008-05-13 Added DEFINITION Catalysis of the reaction: succinate + quinone = fumarate + quinol.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: succinate + quinone = fumarate + quinol.
2007-11-08 Added SYNONYM menaquinol: fumarate oxidoreductase activity
2007-11-08 Added SYNONYM fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)
2007-11-08 Added SYNONYM complex II
2007-11-08 Added SYNONYM succinate:ubiquinone oxidoreductase activity
2007-11-08 Added SYNONYM succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)
2007-09-06 Added SYNONYM succinic dehydrogenase activity
2007-08-09 Added SYNONYM quinol:fumarate oxidoreductase activity
2007-08-09 Deleted SYNONYM quinol:fumarate oxidoreductase activity
2004-04-19 Added SYNONYM quinol:fumarate oxidoreductase activity
2004-04-16 Deleted SYNONYM quinol:fumarate oxidoreductase activity
2003-12-16 Added SYNONYM quinol:fumarate oxidoreductase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: succinate + quinone = fumarate + quinol.
Timestamp Action Category Detail
2024-05-16 Added RELATION is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor)
2023-09-06 Deleted RELATION is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor)
2009-11-24 Added RELATION is a GO:0000104 (succinate dehydrogenase activity)
2008-04-01 Updated RELATION is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor)
Timestamp Action Category Detail
2023-12-15 Added XREF MetaCyc:RXN-14971
2023-12-15 Added XREF RHEA:40523
2023-12-15 Deleted XREF MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN
2023-12-15 Deleted XREF RHEA:13713
2019-06-20 Added XREF KEGG_REACTION:R02164
2019-06-20 Deleted XREF KEGG:R02164
2019-04-01 Deleted XREF reactome:R-HSA-163213
2019-04-01 Added XREF Reactome:R-HSA-70994
2019-04-01 Deleted XREF reactome:R-HSA-70994
2019-04-01 Added XREF Reactome:R-HSA-163213
2018-12-11 Added XREF reactome:R-HSA-70994
2018-12-11 Added XREF reactome:R-HSA-163213
2018-07-13 Deleted XREF RHEA:13716
2018-07-13 Added XREF RHEA:13713
2010-10-11 Added XREF KEGG:R02164
2010-10-11 Added XREF RHEA:13716
2009-05-21 Added XREF MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN
2001-03-30 Added XREF EC:1.3.5.1
Timestamp Action Category Detail
2003-12-16 Added SECONDARY GO:0019737 (quinol:fumarate oxidoreductase activity)
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