This term is obsolete.

GO:0008255 JSON

ecdysis-triggering hormone activity

Molecular Function

Definition (GO:0008255 GONUTS page)

The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system. PMID:9020043

382 annotations

Ancestor Chart

Ancestor chart for GO:0008255
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O95970 9606 LGI1_HUMAN GO:0005102 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein Q8K4Y5 10116 LGI1_RAT GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q9HCQ7-PRO_0000009923 9606 NPVF_HUMAN GO:0160041 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18752651

Cross-references

Database ID Description
InterPro IPR006825 Eclosion hormone

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008255 based on ALL annotations
The top 32 of 32 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ecdysis-triggering hormone activity
512,996.78 100.00 380 380
ecdysis, chitin-based cuticle
332,582.28 63.15 365 563
neuropeptide signaling pathway
2,307.16 0.45 380 84,493
eclosion hormone activity
512,996.80 0.26 1 1
regulation of eclosion
24,428.42 0.25 1 21
myostimulatory hormone activity
21,374.87 0.25 1 24
eclosion
14,249.91 0.24 1 36
larval feeding behavior
2,060.23 0.16 1 249
hormone activity
802.22 0.16 132 84,410
neuropeptide receptor binding
1,654.83 0.15 1 310
Totals 1473 127741974
No co-occurrence statistics for GO:0008255 based on MANUAL annotations
The top 13 of 13 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ecdysis-triggering hormone activity
430,599.70 100.00 3 3
myostimulatory hormone activity
61,514.24 11.11 1 7
ecdysis, chitin-based cuticle
36,908.54 8.57 3 35
neuropeptide receptor binding
17,941.65 3.85 1 24
larval feeding behavior
9,360.86 2.08 1 46
neuropeptide hormone activity
1,944.02 0.45 2 443
neuropeptide signaling pathway
829.14 0.19 3 1,558
G protein-coupled receptor binding
750.83 0.17 2 1,147
hormone activity
475.28 0.11 1 906
signaling receptor binding
253.59 0.06 2 3,396
Totals 25 57024

Change Log

Timestamp Action Category Detail
2009-01-12 Added DEFINITION The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system.
2008-04-01 Updated RELATION is a GO:0005184 (neuropeptide hormone activity)
2003-03-19 Updated TERM ecdysis-triggering hormone activity
2002-02-06 Updated TERM ecdysis-triggering hormone
2001-04-03 Updated TERM ecdysis-triggering hormone
2001-03-30 Added TERM ecdysis-triggering hormone
Timestamp Action Category Detail
2003-03-19 Updated TERM ecdysis-triggering hormone activity
2002-02-06 Updated TERM ecdysis-triggering hormone
2001-04-03 Updated TERM ecdysis-triggering hormone
2001-03-30 Added TERM ecdysis-triggering hormone
Timestamp Action Category Detail
2009-01-12 Added DEFINITION The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005184 (neuropeptide hormone activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
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