This term is obsolete.

GO:0008289 JSON

lipid binding

Molecular Function

Definition (GO:0008289 GONUTS page)

Binding to a lipid.

1,559,952 annotations

Ancestor Chart

Ancestor chart for GO:0008289
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008289

Child Term Relationship to
GO:0008289
diacylglycerol binding
is_a
fatty acid binding
is_a
fatty acid derivative binding
is_a
triglyceride binding
is_a
steroid binding
is_a
lipopolysaccharide binding
is_a
regulation of lipid binding
regulates
negative regulation of lipid binding
negatively_regulates
sphingolipid binding
is_a
lipid antigen binding
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P05943 10116 S10AA_RAT GO:0008289 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P60903 9606 S10AA_HUMAN GO:0008289 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23861394

Cross-references

Database ID Description
InterPro IPR000074 Apolipoprotein A/E
InterPro IPR000463 Cytosolic fatty-acid binding
InterPro IPR000528 Plant non-specific lipid-transfer protein/Par allergen
InterPro IPR000648 Oxysterol-binding protein
InterPro IPR000799 Steroidogenic acute regulatory protein-like
InterPro IPR001124 Lipid-binding serum glycoprotein, C-terminal
InterPro IPR002913 START domain
InterPro IPR002969 Apolipoprotein D
InterPro IPR006801 Apolipoprotein A-II (ApoA-II)
InterPro IPR008403 Apolipoprotein CIII

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:18059 lipid

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0006630 obsolete lipid binding consider GO:0008289

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008289 based on ALL annotations
The top 100 of 5,715 co-occurring terms
Co-occurring Term PR S% #Together #Compared
lipid binding
447.90 100.00 435,228 435,228
lipid transport
146.14 16.19 105,834 324,372
proton-transporting ATP synthase complex, coupling factor F(o)
96.69 9.15 59,634 276,255
proton transmembrane transporter activity
75.02 8.17 59,887 357,529
proton motive force-driven ATP synthesis
43.88 6.05 59,491 607,259
sterol binding
268.14 5.07 22,863 38,190
ATP biosynthetic process
36.82 5.03 50,024 608,457
proton-transporting ATP synthase activity, rotational mechanism
37.71 5.02 48,109 571,432
endocytosis
57.43 4.93 32,234 251,377
cholesterol binding
220.43 4.92 22,551 45,823
Totals 1776113 26783292
No co-occurrence statistics for GO:0008289 based on MANUAL annotations
The top 100 of 2,220 co-occurring terms
Co-occurring Term PR S% #Together #Compared
lipid binding
1,098.47 100.00 1,176 1,176
mitochondrial fission
269.05 8.39 133 543
peroxisome fission
237.85 7.94 131 605
phospholipase A2 activity
265.22 7.73 120 497
plasma membrane tubulation
319.94 6.45 90 309
lipoprotein transport
419.00 5.71 74 194
actin cortical patch localization
226.26 4.38 62 301
ubiquinone biosynthetic process
76.33 3.92 97 1,396
pollen germination
446.83 3.85 48 118
peroxisomal membrane
60.05 3.83 133 2,433
Totals 4512 68302

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_generic 141
goslim_candida 86
goslim_pir 439
goslim_yeast 163
goslim_plant 97
goslim_prokaryote 97
goslim_chembl 296
goslim_mouse 45
goslim_agr 53
goslim_flybase_ribbon 44
goslim_drosophila 173
goslim_euk_cellular_processes_ribbon 61
goslim_plant_ribbon 62
goslim_prokaryote_ribbon 49

Change Log

Timestamp Action Category Detail
2024-09-02 Added RELATION has part GO:0140090 (membrane curvature sensor activity)
2024-03-21 Added SUBSET goslim_prokaryote_ribbon
2024-03-21 Added SUBSET goslim_plant_ribbon
2024-03-21 Added SUBSET goslim_euk_cellular_processes_ribbon
2023-12-15 Added SUBSET goslim_prokaryote
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a lipid.
2021-05-24 Added DEFINITION Binding to a lipid.
2020-02-28 Deleted XREF MIPS_funcat:16.09
2020-02-07 Deleted RELATION has part GO:0140362 (cytoskeletal protein membrane adaptor)
2020-02-07 Added RELATION has part GO:0106006 (cytoskeletal protein-membrane anchor activity)
Timestamp Action Category Detail
2003-06-10 Updated TERM lipid binding
2003-03-19 Updated TERM lipid binding activity
2002-02-06 Updated TERM lipid binding
2001-04-03 Updated TERM lipid binding
2001-03-30 Added TERM lipid binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a lipid.
2021-05-24 Added DEFINITION Binding to a lipid.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a lipid.
2009-07-03 Deleted DEFINITION Interacting selectively with a lipid.
2008-05-13 Added DEFINITION Interacting selectively with a lipid.
2008-05-12 Deleted DEFINITION Interacting selectively with a lipid.
2003-03-26 Updated DEFINITION Interacting selectively with a lipid.
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with a lipid.
Timestamp Action Category Detail
2024-09-02 Added RELATION has part GO:0140090 (membrane curvature sensor activity)
2020-02-07 Deleted RELATION has part GO:0140362 (cytoskeletal protein membrane adaptor)
2020-02-07 Added RELATION has part GO:0106006 (cytoskeletal protein-membrane anchor activity)
2019-07-11 Added RELATION has part GO:0140362 (cytoskeletal protein membrane adaptor)
2019-04-18 Deleted RELATION has part GO:0120013 (lipid transfer activity)
2017-03-19 Added RELATION has part GO:0120013 (lipid transfer activity)
2008-04-01 Updated RELATION is a GO:0005488 (binding)
Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:16.09
2019-05-04 Added XREF MIPS_funcat:16.09
Timestamp Action Category Detail
2024-03-21 Added SUBSET goslim_prokaryote_ribbon
2024-03-21 Added SUBSET goslim_plant_ribbon
2024-03-21 Added SUBSET goslim_euk_cellular_processes_ribbon
2023-12-15 Added SUBSET goslim_prokaryote
2019-11-09 Added SUBSET goslim_drosophila
2018-09-22 Added SUBSET goslim_flybase_ribbon
2017-07-08 Added SUBSET goslim_agr
2016-12-17 Added SUBSET goslim_mouse
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-19 Added SUBSET goslim_chembl
2015-05-11 Added SUBSET goslim_ChEMBL
2013-04-18 Updated SUBSET goslim_generic
2013-04-18 Updated SUBSET goslim_pir
2013-04-18 Updated SUBSET goslim_plant
2013-04-18 Updated SUBSET goslim_candida
2013-04-18 Updated SUBSET goslim_yeast
2012-02-10 Added SUBSET goslim_generic
2010-12-05 Deleted SUBSET goslim_generic
2008-06-09 Added SUBSET goslim_generic
2008-06-09 Added SUBSET goslim_candida
2008-06-09 Added SUBSET goslim_yeast
2008-06-09 Added SUBSET goslim_pir
2008-06-09 Added SUBSET goslim_plant
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