GO:0008320
JSON
protein transmembrane transporter activity
Molecular Function
Definition (GO:0008320 GONUTS page)
Enables the transfer of a protein from one side of a membrane to the other.
Secondary IDs
GO:0015266, GO:0015463
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
protein channel activity | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0008320
Child Term | Relationship to GO:0008320 |
---|---|
curli secretion complex
|
capable_of |
proton motive force dependent protein transmembrane transporter activity
|
is_a |
protein-transporting ATPase activity
|
is_a |
lactoferrin transmembrane transporter activity
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02650 | 10116 | APOE_RAT | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P04639 | 10116 | APOA1_RAT | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P08226 | 10090 | APOE_MOUSE | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076 | |
NOT-qualified manual | protein | Q00623 | 10090 | APOA1_MOUSE | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR005678 | Mitochondrial inner membrane translocase complex, subunit Tim17 |
InterPro | IPR005681 | Mitochondrial inner membrane translocase complex, subunit Tim23 |
InterPro | IPR005686 | Mitochondrial import receptor subunit Tom40, fungi |
InterPro | IPR005807 | SecE subunit of protein translocation complex, bacterial-like |
InterPro | IPR008158 | Protein translocase SEC61 complex, gamma subunit |
InterPro | IPR012500 | Clostridium neurotoxin, translocation |
InterPro | IPR018448 | Sec-independent protein translocase protein TatB |
InterPro | IPR037930 | Tom40 |
Reactome | R-HSA-1268022 | |
Reactome | R-HSA-1299475 |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0015480 | obsolete secretin (sensu Bacteria) | consider GO:0008320 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008320 based on ALL annotations
The top 100 of 829 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein transmembrane transporter activity
|
1,002.10 | 100.00 | 194,531 | 194,531 |
protein transport by the Tat complex
|
919.69 | 46.28 | 93,930 | 102,346 |
TAT protein transport complex
|
942.74 | 45.51 | 91,136 | 96,874 |
intracellular protein transmembrane transport
|
270.29 | 18.29 | 70,518 | 261,441 |
proton motive force dependent protein transmembrane transporter activity
|
862.97 | 17.71 | 35,462 | 41,179 |
protein import into mitochondrial matrix
|
390.95 | 10.77 | 25,195 | 64,580 |
protein targeting
|
154.33 | 10.35 | 46,696 | 303,203 |
protein secretion by the type V secretion system
|
1,001.78 | 9.75 | 18,963 | 18,969 |
type V protein secretion system complex
|
1,001.99 | 9.73 | 18,928 | 18,930 |
protein transport by the Sec complex
|
157.52 | 9.11 | 34,671 | 220,569 |
Totals | 1374545 | 108082336 |
No co-occurrence statistics for GO:0008320 based on MANUAL annotations
The top 100 of 399 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein transmembrane transporter activity
|
722.48 | 100.00 | 1,788 | 1,788 |
protein import into mitochondrial matrix
|
230.21 | 20.08 | 629 | 1,974 |
mitochondrion targeting sequence binding
|
718.45 | 19.89 | 356 | 358 |
signal sequence binding
|
671.16 | 18.74 | 340 | 366 |
post-translational protein targeting to membrane, translocation
|
366.98 | 17.78 | 384 | 756 |
SRP-dependent cotranslational protein targeting to membrane, translocation
|
358.15 | 16.21 | 347 | 700 |
TIM23 mitochondrial import inner membrane translocase complex
|
258.98 | 14.56 | 352 | 982 |
protein insertion into mitochondrial inner membrane
|
320.62 | 13.56 | 292 | 658 |
mitochondrial outer membrane translocase complex
|
565.02 | 13.15 | 244 | 312 |
TIM22 mitochondrial import inner membrane insertion complex
|
575.04 | 12.66 | 234 | 294 |
Totals | 7327 | 45705 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-06-13 | Deleted | RELATION | is a GO:0022857 (transmembrane transporter activity) |
2023-06-13 | Added | RELATION | is a GO:0022884 (macromolecule transmembrane transporter activity) |
2023-05-20 | Deleted | RELATION | is a GO:0022884 (macromolecule transmembrane transporter activity) |
2023-05-20 | Added | RELATION | is a GO:0022857 (transmembrane transporter activity) |
2021-03-12 | Deleted | RELATION | is a GO:1904680 (peptide transmembrane transporter activity) |
2020-12-17 | Added | XREF | Reactome:R-HSA-9698930 |
2020-12-17 | Added | XREF | Reactome:R-HSA-9698933 |
2020-07-19 | Added | XREF | Reactome:R-HSA-9636375 |
2020-07-19 | Added | XREF | Reactome:R-HSA-3149434 |
2020-07-19 | Added | XREF | Reactome:R-HSA-184269 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-10-07 | Updated | TERM | protein transmembrane transporter activity |
2003-03-19 | Updated | TERM | protein carrier activity |
2002-02-06 | Updated | TERM | protein carrier |
2001-04-03 | Updated | TERM | protein carrier |
2001-03-30 | Added | TERM | protein carrier |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-01-12 | Added | SYNONYM | protein channel activity |
2015-05-11 | Deleted | DEFINITION | Catalysis of the transfer of a protein from one side of a membrane to the other. |
2015-05-11 | Added | DEFINITION | Enables the transfer of a protein from one side of a membrane to the other. |
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of a protein from one side of a membrane to the other. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the transfer of a protein from one side of a membrane to the other. |
2007-10-25 | Updated | DEFINITION | Catalysis of the transfer of a protein from one side of a membrane to the other. |
2007-10-12 | Deleted | SYNONYM | protein carrier activity |
2007-10-07 | Added | SYNONYM | protein carrier activity |
2006-04-19 | Updated | DEFINITION | Catalysis of the transfer of proteins from one side of a membrane to the other. |
2004-08-12 | Added | DEFINITION | Catalysis of the transfer of proteins from one side of the membrane to the other. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-06-13 | Deleted | RELATION | is a GO:0022857 (transmembrane transporter activity) |
2023-06-13 | Added | RELATION | is a GO:0022884 (macromolecule transmembrane transporter activity) |
2023-05-20 | Deleted | RELATION | is a GO:0022884 (macromolecule transmembrane transporter activity) |
2023-05-20 | Added | RELATION | is a GO:0022857 (transmembrane transporter activity) |
2021-03-12 | Deleted | RELATION | is a GO:1904680 (peptide transmembrane transporter activity) |
2019-05-29 | Added | RELATION | is a GO:0140318 (protein transporter activity) |
2019-04-18 | Deleted | RELATION | is a GO:0008565 (obsolete protein transporter activity) |
2017-02-23 | Added | RELATION | is a GO:1904680 (peptide transmembrane transporter activity) |
2014-01-08 | Added | RELATION | part of GO:0071806 (protein transmembrane transport) |
2010-06-15 | Deleted | RELATION | is a GO:0005515 (protein binding) |
2010-05-19 | Added | RELATION | is a GO:0022884 (macromolecule transmembrane transporter activity) |
2010-05-19 | Deleted | RELATION | is a GO:0022891 (substrate-specific transmembrane transporter activity) |
2008-04-01 | Updated | RELATION | is a GO:0022891 (substrate-specific transmembrane transporter activity) |
2008-04-01 | Updated | RELATION | is a GO:0005515 (protein binding) |
2008-04-01 | Updated | RELATION | is a GO:0008565 (obsolete protein transporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-12-17 | Added | XREF | Reactome:R-HSA-9698930 |
2020-12-17 | Added | XREF | Reactome:R-HSA-9698933 |
2020-07-19 | Added | XREF | Reactome:R-HSA-9636375 |
2020-07-19 | Added | XREF | Reactome:R-HSA-3149434 |
2020-07-19 | Added | XREF | Reactome:R-HSA-184269 |
2020-07-19 | Added | XREF | Reactome:R-HSA-5229111 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5250884 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5244506 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5246514 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5210947 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5205661 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-1268022 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5210947 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5336420 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5250616 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5205661 |
2019-04-01 | Added | XREF | Reactome:R-HSA-1299475 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5244428 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5210943 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5250972 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5244404 |
2019-04-01 | Added | XREF | Reactome:R-HSA-1268022 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5228406 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5336420 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5250884 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5244506 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5228406 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5210943 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5244428 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-1299475 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5250616 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5250972 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5244404 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5246514 |
2018-12-11 | Added | XREF | reactome:R-HSA-5228406 |
2018-12-11 | Added | XREF | reactome:R-HSA-5205661 |
2018-12-11 | Added | XREF | reactome:R-HSA-5210947 |
2018-12-11 | Added | XREF | reactome:R-HSA-1268022 |
2018-12-11 | Added | XREF | reactome:R-HSA-5210943 |
2018-12-11 | Added | XREF | reactome:R-HSA-5246514 |
2018-12-11 | Added | XREF | reactome:R-HSA-5244506 |
2018-12-11 | Added | XREF | reactome:R-HSA-5250616 |
2018-12-11 | Added | XREF | reactome:R-HSA-1299475 |
2018-12-11 | Added | XREF | reactome:R-HSA-5244404 |
2018-12-11 | Added | XREF | reactome:R-HSA-5336420 |
2018-12-11 | Added | XREF | reactome:R-HSA-5244428 |
2018-12-11 | Added | XREF | reactome:R-HSA-5250884 |
2018-12-11 | Added | XREF | reactome:R-HSA-5250972 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-18 | Added | SECONDARY | GO:0015463 (enzyme transporter activity) |
2018-01-12 | Added | SECONDARY | GO:0015266 (protein channel activity) |
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