This term is obsolete.

GO:0008320 JSON

protein transmembrane transporter activity

Molecular Function

Definition (GO:0008320 GONUTS page)

Enables the transfer of a protein from one side of a membrane to the other.

Secondary IDs

GO:0015266, GO:0015463

357,052 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
protein channel activity related

Ancestor Chart

Ancestor chart for GO:0008320
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008320

Child Term Relationship to
GO:0008320
protein-transporting ATPase activity
is_a
lactoferrin transmembrane transporter activity
is_a
curli secretion complex
capable_of
proton motive force dependent protein transmembrane transporter activity
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02650 10116 APOE_RAT GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P04639 10116 APOA1_RAT GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P08226 10090 APOE_MOUSE GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076
NOT-qualified manual protein Q00623 10090 APOA1_MOUSE GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076

Cross-references

Database ID Description
InterPro IPR005678 Mitochondrial inner membrane translocase complex, subunit Tim17
InterPro IPR005681 Mitochondrial inner membrane translocase complex, subunit Tim23
InterPro IPR005686 Mitochondrial import receptor subunit Tom40, fungi
InterPro IPR005807 SecE subunit of protein translocation complex, bacterial-like
InterPro IPR008158 Protein translocase SEC61 complex, gamma subunit
InterPro IPR012500 Clostridium neurotoxin, translocation
InterPro IPR018448 Sec-independent protein translocase protein TatB
InterPro IPR037930 Tom40
Reactome R-HSA-1268022
Reactome R-HSA-1299475

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0015480 obsolete secretin (sensu Bacteria) consider GO:0008320

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008320 based on ALL annotations
The top 100 of 835 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein transmembrane transporter activity
1,000.52 100.00 198,051 198,051
protein transport by the Tat complex
915.47 46.00 95,174 104,016
TAT protein transport complex
939.28 45.25 92,343 98,364
intracellular protein transmembrane transport
270.56 18.26 71,243 263,457
proton motive force dependent protein transmembrane transporter activity
856.77 17.53 35,761 41,761
protein import into mitochondrial matrix
390.78 10.91 26,053 66,705
protein targeting
154.94 10.38 47,444 306,364
protein secretion by the type V secretion system
1,000.21 9.68 19,169 19,175
type V protein secretion system complex
1,000.42 9.66 19,134 19,136
protein transport by the Sec complex
158.13 9.12 35,145 222,372
Totals 1386409 109530946
No co-occurrence statistics for GO:0008320 based on MANUAL annotations
The top 100 of 400 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein transmembrane transporter activity
739.80 100.00 1,908 1,908
protein import into mitochondrial matrix
246.37 21.20 703 2,111
signal sequence binding
694.02 19.61 379 404
post-translational protein targeting to membrane, translocation
385.98 18.75 432 828
mitochondrion targeting sequence binding
735.30 17.12 327 329
SRP-dependent cotranslational protein targeting to membrane, translocation
369.90 16.83 386 772
TIM23 mitochondrial import inner membrane translocase complex
266.92 15.12 394 1,092
mitochondrial outer membrane translocase complex
579.61 13.86 275 351
Sec61 translocon complex
569.07 12.61 250 325
protein insertion into mitochondrial inner membrane
308.97 11.12 251 601
Totals 7794 50775

Change Log

Timestamp Action Category Detail
2023-06-13 Deleted RELATION is a GO:0022857 (transmembrane transporter activity)
2023-06-13 Added RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2023-05-20 Added RELATION is a GO:0022857 (transmembrane transporter activity)
2023-05-20 Deleted RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2021-03-12 Deleted RELATION is a GO:1904680 (peptide transmembrane transporter activity)
2020-12-17 Added XREF Reactome:R-HSA-9698933
2020-12-17 Added XREF Reactome:R-HSA-9698930
2020-07-19 Added XREF Reactome:R-HSA-9636375
2020-07-19 Added XREF Reactome:R-HSA-5229111
2020-07-19 Added XREF Reactome:R-HSA-184269
Timestamp Action Category Detail
2007-10-07 Updated TERM protein transmembrane transporter activity
2003-03-19 Updated TERM protein carrier activity
2002-02-06 Updated TERM protein carrier
2001-04-03 Updated TERM protein carrier
2001-03-30 Added TERM protein carrier
Timestamp Action Category Detail
2018-01-12 Added SYNONYM protein channel activity
2015-05-11 Added DEFINITION Enables the transfer of a protein from one side of a membrane to the other.
2015-05-11 Deleted DEFINITION Catalysis of the transfer of a protein from one side of a membrane to the other.
2008-05-13 Added DEFINITION Catalysis of the transfer of a protein from one side of a membrane to the other.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a protein from one side of a membrane to the other.
2007-10-25 Updated DEFINITION Catalysis of the transfer of a protein from one side of a membrane to the other.
2007-10-12 Deleted SYNONYM protein carrier activity
2007-10-07 Added SYNONYM protein carrier activity
2006-04-19 Updated DEFINITION Catalysis of the transfer of proteins from one side of a membrane to the other.
2004-08-12 Added DEFINITION Catalysis of the transfer of proteins from one side of the membrane to the other.
Timestamp Action Category Detail
2023-06-13 Deleted RELATION is a GO:0022857 (transmembrane transporter activity)
2023-06-13 Added RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2023-05-20 Added RELATION is a GO:0022857 (transmembrane transporter activity)
2023-05-20 Deleted RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2021-03-12 Deleted RELATION is a GO:1904680 (peptide transmembrane transporter activity)
2019-05-29 Added RELATION is a GO:0140318 (protein transporter activity)
2019-04-18 Deleted RELATION is a GO:0008565 (obsolete protein transporter activity)
2017-02-23 Added RELATION is a GO:1904680 (peptide transmembrane transporter activity)
2014-01-08 Added RELATION part of GO:0071806 (protein transmembrane transport)
2010-06-15 Deleted RELATION is a GO:0005515 (protein binding)
2010-05-19 Added RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2010-05-19 Deleted RELATION is a GO:0022891 (substrate-specific transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0008565 (obsolete protein transporter activity)
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
2008-04-01 Updated RELATION is a GO:0022891 (substrate-specific transmembrane transporter activity)
Timestamp Action Category Detail
2020-12-17 Added XREF Reactome:R-HSA-9698933
2020-12-17 Added XREF Reactome:R-HSA-9698930
2020-07-19 Added XREF Reactome:R-HSA-9636375
2020-07-19 Added XREF Reactome:R-HSA-5229111
2020-07-19 Added XREF Reactome:R-HSA-184269
2020-07-19 Added XREF Reactome:R-HSA-3149434
2019-04-01 Deleted XREF reactome:R-HSA-5246514
2019-04-01 Added XREF Reactome:R-HSA-5250884
2019-04-01 Added XREF Reactome:R-HSA-5246514
2019-04-01 Deleted XREF reactome:R-HSA-5210947
2019-04-01 Deleted XREF reactome:R-HSA-5205661
2019-04-01 Deleted XREF reactome:R-HSA-1268022
2019-04-01 Added XREF Reactome:R-HSA-5210947
2019-04-01 Added XREF Reactome:R-HSA-5336420
2019-04-01 Added XREF Reactome:R-HSA-5250616
2019-04-01 Added XREF Reactome:R-HSA-5205661
2019-04-01 Added XREF Reactome:R-HSA-1299475
2019-04-01 Added XREF Reactome:R-HSA-5244428
2019-04-01 Added XREF Reactome:R-HSA-5210943
2019-04-01 Added XREF Reactome:R-HSA-5250972
2019-04-01 Added XREF Reactome:R-HSA-5244404
2019-04-01 Added XREF Reactome:R-HSA-1268022
2019-04-01 Added XREF Reactome:R-HSA-5228406
2019-04-01 Deleted XREF reactome:R-HSA-5336420
2019-04-01 Deleted XREF reactome:R-HSA-5250884
2019-04-01 Deleted XREF reactome:R-HSA-5244506
2019-04-01 Deleted XREF reactome:R-HSA-5244428
2019-04-01 Added XREF Reactome:R-HSA-5244506
2019-04-01 Deleted XREF reactome:R-HSA-5244404
2019-04-01 Deleted XREF reactome:R-HSA-5210943
2019-04-01 Deleted XREF reactome:R-HSA-5228406
2019-04-01 Deleted XREF reactome:R-HSA-1299475
2019-04-01 Deleted XREF reactome:R-HSA-5250616
2019-04-01 Deleted XREF reactome:R-HSA-5250972
2018-12-11 Added XREF reactome:R-HSA-5210943
2018-12-11 Added XREF reactome:R-HSA-5244428
2018-12-11 Added XREF reactome:R-HSA-5250884
2018-12-11 Added XREF reactome:R-HSA-5336420
2018-12-11 Added XREF reactome:R-HSA-5244404
2018-12-11 Added XREF reactome:R-HSA-5246514
2018-12-11 Added XREF reactome:R-HSA-5228406
2018-12-11 Added XREF reactome:R-HSA-1299475
2018-12-11 Added XREF reactome:R-HSA-1268022
2018-12-11 Added XREF reactome:R-HSA-5205661
2018-12-11 Added XREF reactome:R-HSA-5244506
2018-12-11 Added XREF reactome:R-HSA-5250972
2018-12-11 Added XREF reactome:R-HSA-5250616
2018-12-11 Added XREF reactome:R-HSA-5210947
Timestamp Action Category Detail
2019-04-18 Added SECONDARY GO:0015463 (enzyme transporter activity)
2018-01-12 Added SECONDARY GO:0015266 (protein channel activity)
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