This term is obsolete.

GO:0008320 JSON

protein transmembrane transporter activity

Molecular Function

Definition (GO:0008320 GONUTS page)

Enables the transfer of a protein from one side of a membrane to the other.

Secondary IDs

GO:0015266, GO:0015463

351,355 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
protein channel activity related

Ancestor Chart

Ancestor chart for GO:0008320
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008320

Child Term Relationship to
GO:0008320
curli secretion complex
capable_of
proton motive force dependent protein transmembrane transporter activity
is_a
protein-transporting ATPase activity
is_a
lactoferrin transmembrane transporter activity
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02650 10116 APOE_RAT GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P04639 10116 APOA1_RAT GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P08226 10090 APOE_MOUSE GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076
NOT-qualified manual protein Q00623 10090 APOA1_MOUSE GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076

Cross-references

Database ID Description
InterPro IPR005678 Mitochondrial inner membrane translocase complex, subunit Tim17
InterPro IPR005681 Mitochondrial inner membrane translocase complex, subunit Tim23
InterPro IPR005686 Mitochondrial import receptor subunit Tom40, fungi
InterPro IPR005807 SecE subunit of protein translocation complex, bacterial-like
InterPro IPR008158 Protein translocase SEC61 complex, gamma subunit
InterPro IPR012500 Clostridium neurotoxin, translocation
InterPro IPR018448 Sec-independent protein translocase protein TatB
InterPro IPR037930 Tom40
Reactome R-HSA-1268022
Reactome R-HSA-1299475

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0015480 obsolete secretin (sensu Bacteria) consider GO:0008320

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008320 based on ALL annotations
The top 100 of 829 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein transmembrane transporter activity
1,002.10 100.00 194,531 194,531
protein transport by the Tat complex
919.69 46.28 93,930 102,346
TAT protein transport complex
942.74 45.51 91,136 96,874
intracellular protein transmembrane transport
270.29 18.29 70,518 261,441
proton motive force dependent protein transmembrane transporter activity
862.97 17.71 35,462 41,179
protein import into mitochondrial matrix
390.95 10.77 25,195 64,580
protein targeting
154.33 10.35 46,696 303,203
protein secretion by the type V secretion system
1,001.78 9.75 18,963 18,969
type V protein secretion system complex
1,001.99 9.73 18,928 18,930
protein transport by the Sec complex
157.52 9.11 34,671 220,569
Totals 1374545 108082336
No co-occurrence statistics for GO:0008320 based on MANUAL annotations
The top 100 of 399 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein transmembrane transporter activity
722.48 100.00 1,788 1,788
protein import into mitochondrial matrix
230.21 20.08 629 1,974
mitochondrion targeting sequence binding
718.45 19.89 356 358
signal sequence binding
671.16 18.74 340 366
post-translational protein targeting to membrane, translocation
366.98 17.78 384 756
SRP-dependent cotranslational protein targeting to membrane, translocation
358.15 16.21 347 700
TIM23 mitochondrial import inner membrane translocase complex
258.98 14.56 352 982
protein insertion into mitochondrial inner membrane
320.62 13.56 292 658
mitochondrial outer membrane translocase complex
565.02 13.15 244 312
TIM22 mitochondrial import inner membrane insertion complex
575.04 12.66 234 294
Totals 7327 45705

Change Log

Timestamp Action Category Detail
2023-06-13 Deleted RELATION is a GO:0022857 (transmembrane transporter activity)
2023-06-13 Added RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2023-05-20 Deleted RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2023-05-20 Added RELATION is a GO:0022857 (transmembrane transporter activity)
2021-03-12 Deleted RELATION is a GO:1904680 (peptide transmembrane transporter activity)
2020-12-17 Added XREF Reactome:R-HSA-9698930
2020-12-17 Added XREF Reactome:R-HSA-9698933
2020-07-19 Added XREF Reactome:R-HSA-9636375
2020-07-19 Added XREF Reactome:R-HSA-3149434
2020-07-19 Added XREF Reactome:R-HSA-184269
Timestamp Action Category Detail
2007-10-07 Updated TERM protein transmembrane transporter activity
2003-03-19 Updated TERM protein carrier activity
2002-02-06 Updated TERM protein carrier
2001-04-03 Updated TERM protein carrier
2001-03-30 Added TERM protein carrier
Timestamp Action Category Detail
2018-01-12 Added SYNONYM protein channel activity
2015-05-11 Deleted DEFINITION Catalysis of the transfer of a protein from one side of a membrane to the other.
2015-05-11 Added DEFINITION Enables the transfer of a protein from one side of a membrane to the other.
2008-05-13 Added DEFINITION Catalysis of the transfer of a protein from one side of a membrane to the other.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a protein from one side of a membrane to the other.
2007-10-25 Updated DEFINITION Catalysis of the transfer of a protein from one side of a membrane to the other.
2007-10-12 Deleted SYNONYM protein carrier activity
2007-10-07 Added SYNONYM protein carrier activity
2006-04-19 Updated DEFINITION Catalysis of the transfer of proteins from one side of a membrane to the other.
2004-08-12 Added DEFINITION Catalysis of the transfer of proteins from one side of the membrane to the other.
Timestamp Action Category Detail
2023-06-13 Deleted RELATION is a GO:0022857 (transmembrane transporter activity)
2023-06-13 Added RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2023-05-20 Deleted RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2023-05-20 Added RELATION is a GO:0022857 (transmembrane transporter activity)
2021-03-12 Deleted RELATION is a GO:1904680 (peptide transmembrane transporter activity)
2019-05-29 Added RELATION is a GO:0140318 (protein transporter activity)
2019-04-18 Deleted RELATION is a GO:0008565 (obsolete protein transporter activity)
2017-02-23 Added RELATION is a GO:1904680 (peptide transmembrane transporter activity)
2014-01-08 Added RELATION part of GO:0071806 (protein transmembrane transport)
2010-06-15 Deleted RELATION is a GO:0005515 (protein binding)
2010-05-19 Added RELATION is a GO:0022884 (macromolecule transmembrane transporter activity)
2010-05-19 Deleted RELATION is a GO:0022891 (substrate-specific transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0022891 (substrate-specific transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
2008-04-01 Updated RELATION is a GO:0008565 (obsolete protein transporter activity)
Timestamp Action Category Detail
2020-12-17 Added XREF Reactome:R-HSA-9698930
2020-12-17 Added XREF Reactome:R-HSA-9698933
2020-07-19 Added XREF Reactome:R-HSA-9636375
2020-07-19 Added XREF Reactome:R-HSA-3149434
2020-07-19 Added XREF Reactome:R-HSA-184269
2020-07-19 Added XREF Reactome:R-HSA-5229111
2019-04-01 Added XREF Reactome:R-HSA-5250884
2019-04-01 Added XREF Reactome:R-HSA-5244506
2019-04-01 Added XREF Reactome:R-HSA-5246514
2019-04-01 Deleted XREF reactome:R-HSA-5210947
2019-04-01 Deleted XREF reactome:R-HSA-5205661
2019-04-01 Deleted XREF reactome:R-HSA-1268022
2019-04-01 Added XREF Reactome:R-HSA-5210947
2019-04-01 Added XREF Reactome:R-HSA-5336420
2019-04-01 Added XREF Reactome:R-HSA-5250616
2019-04-01 Added XREF Reactome:R-HSA-5205661
2019-04-01 Added XREF Reactome:R-HSA-1299475
2019-04-01 Added XREF Reactome:R-HSA-5244428
2019-04-01 Added XREF Reactome:R-HSA-5210943
2019-04-01 Added XREF Reactome:R-HSA-5250972
2019-04-01 Added XREF Reactome:R-HSA-5244404
2019-04-01 Added XREF Reactome:R-HSA-1268022
2019-04-01 Added XREF Reactome:R-HSA-5228406
2019-04-01 Deleted XREF reactome:R-HSA-5336420
2019-04-01 Deleted XREF reactome:R-HSA-5250884
2019-04-01 Deleted XREF reactome:R-HSA-5244506
2019-04-01 Deleted XREF reactome:R-HSA-5228406
2019-04-01 Deleted XREF reactome:R-HSA-5210943
2019-04-01 Deleted XREF reactome:R-HSA-5244428
2019-04-01 Deleted XREF reactome:R-HSA-1299475
2019-04-01 Deleted XREF reactome:R-HSA-5250616
2019-04-01 Deleted XREF reactome:R-HSA-5250972
2019-04-01 Deleted XREF reactome:R-HSA-5244404
2019-04-01 Deleted XREF reactome:R-HSA-5246514
2018-12-11 Added XREF reactome:R-HSA-5228406
2018-12-11 Added XREF reactome:R-HSA-5205661
2018-12-11 Added XREF reactome:R-HSA-5210947
2018-12-11 Added XREF reactome:R-HSA-1268022
2018-12-11 Added XREF reactome:R-HSA-5210943
2018-12-11 Added XREF reactome:R-HSA-5246514
2018-12-11 Added XREF reactome:R-HSA-5244506
2018-12-11 Added XREF reactome:R-HSA-5250616
2018-12-11 Added XREF reactome:R-HSA-1299475
2018-12-11 Added XREF reactome:R-HSA-5244404
2018-12-11 Added XREF reactome:R-HSA-5336420
2018-12-11 Added XREF reactome:R-HSA-5244428
2018-12-11 Added XREF reactome:R-HSA-5250884
2018-12-11 Added XREF reactome:R-HSA-5250972
Timestamp Action Category Detail
2019-04-18 Added SECONDARY GO:0015463 (enzyme transporter activity)
2018-01-12 Added SECONDARY GO:0015266 (protein channel activity)
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