GO:0008412
JSON
4-hydroxybenzoate polyprenyltransferase activity
Molecular Function
Definition (GO:0008412 GONUTS page)
Catalysis of the reaction: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate.
Secondary IDs
GO:0000043, GO:0048043, GO:0048044
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
4-HB polyprenyltransferase activity | exact |
para-hydroxybenzoate-polyprenyl diphosphate transferase activity | exact |
para-hydroxybenzoate transferase activity | exact |
PHB polyprenyl diphosphate transferase activity | exact |
para-hydroxybenzoate:polyprenyltransferase activity | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I940 | 7227 | Q8I940_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.5.1.39 | |
MetaCyc | RXN-11368 | |
RHEA | 44504 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:17879 | 4-hydroxybenzoate |
has_participant | CHEBI | CHEBI:78396 | 4-hydroxy-3-polyprenylbenzoate |
has_participant | CHEBI | CHEBI:33019 | diphosphate(3-) |
has_participant | CHEBI | CHEBI:58914 | all-trans-polyprenyl diphosphate(3-) |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0002083 | obsolete 4-hydroxybenzoate decaprenyltransferase activity | replaced_by GO:0008412 |
GO:0047293 | obsolete 4-hydroxybenzoate nonaprenyltransferase activity | replaced_by GO:0008412 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008412 based on ALL annotations
The top 100 of 168 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
4-hydroxybenzoate polyprenyltransferase activity
|
10,528.13 | 100.00 | 18,516 | 18,516 |
polyprenyltransferase activity
|
3,534.80 | 11.13 | 2,642 | 7,869 |
ubiquinone biosynthetic process
|
921.11 | 8.74 | 18,416 | 210,491 |
prenyltransferase activity
|
695.54 | 6.56 | 16,826 | 254,687 |
transferase activity, transferring alkyl or aryl (other than methyl) groups
|
277.74 | 2.56 | 8,781 | 332,859 |
isoprenoid biosynthetic process
|
60.66 | 0.56 | 2,682 | 465,500 |
terpenoid biosynthetic process
|
43.87 | 0.38 | 853 | 204,698 |
transferase activity
|
26.26 | 0.25 | 18,048 | 7,234,614 |
mitochondrial inner membrane
|
12.98 | 0.12 | 3,683 | 2,988,420 |
plasma membrane
|
6.97 | 0.07 | 14,782 | 22,337,180 |
Totals | 126838 | 107301313 |
No co-occurrence statistics for GO:0008412 based on MANUAL annotations
The top 24 of 24 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
4-hydroxybenzoate polyprenyltransferase activity
|
12,541.74 | 100.00 | 103 | 103 |
ubiquinone biosynthetic process
|
925.36 | 7.38 | 103 | 1,396 |
transferase activity, transferring alkyl or aryl (other than methyl) groups
|
470.32 | 1.67 | 3 | 80 |
mitochondrial inner membrane
|
168.54 | 1.34 | 94 | 6,995 |
austinol biosynthetic process
|
1,140.16 | 0.88 | 1 | 11 |
dehydroaustinol biosynthetic process
|
964.75 | 0.87 | 1 | 13 |
ubiquinone metabolic process
|
660.09 | 0.83 | 1 | 19 |
prenyltransferase activity
|
63.02 | 0.43 | 3 | 597 |
glycerol metabolic process
|
39.01 | 0.27 | 2 | 643 |
transcription by RNA polymerase III
|
36.94 | 0.26 | 2 | 679 |
Totals | 344 | 201564 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-08 | Deleted | XREF | Reactome:R-HSA-2162192 |
2024-07-12 | Added | XREF | RHEA:44504 |
2024-07-12 | Added | XREF | Reactome:R-HSA-2162192 |
2024-07-12 | Added | XREF | MetaCyc:RXN-11368 |
2024-07-12 | Updated | TERM | 4-hydroxybenzoate polyprenyltransferase activity |
2024-07-12 | Deleted | XREF | RHEA:27782 |
2024-07-12 | Added | DEFINITION | Catalysis of the reaction: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate. |
2024-07-12 | Deleted | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. |
2024-07-12 | Deleted | XREF | MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN |
2021-04-20 | Deleted | XREF | EC:2.5.1.- |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-12 | Updated | TERM | 4-hydroxybenzoate polyprenyltransferase activity |
2003-03-19 | Updated | TERM | 4-hydroxybenzoate octaprenyltransferase activity |
2002-02-06 | Updated | TERM | 4-hydroxybenzoate octaprenyltransferase |
2001-04-03 | Updated | TERM | 4-hydroxybenzoate octaprenyltransferase |
2001-03-30 | Added | TERM | 4-hydroxybenzoate octaprenyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-12 | Added | DEFINITION | Catalysis of the reaction: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate. |
2024-07-12 | Deleted | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. |
2010-09-15 | Deleted | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. |
2010-09-15 | Added | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. |
2007-11-08 | Added | SYNONYM | para-hydroxybenzoate:polyprenyltransferase activity |
2007-11-08 | Deleted | SYNONYM | para-hydroxybenzoate:polyprenyltransferase |
2007-10-06 | Deleted | SYNONYM | 4-hydroxybenzoate octaprenyltransferase activity |
2007-08-09 | Deleted | SYNONYM | 4-HB polyprenyltransferase activity |
2007-08-09 | Deleted | SYNONYM | para-hydroxybenzoate transferase activity |
2007-08-09 | Deleted | SYNONYM | para-hydroxybenzoate-polyprenyl diphosphate transferase activity |
2007-08-09 | Deleted | SYNONYM | para-hydroxybenzoate:polyprenyltransferase |
2007-08-09 | Added | SYNONYM | 4-HB polyprenyltransferase activity |
2007-08-09 | Added | SYNONYM | 4-hydroxybenzoate octaprenyltransferase activity |
2007-08-09 | Added | SYNONYM | PHB polyprenyl diphosphate transferase activity |
2007-08-09 | Added | SYNONYM | para-hydroxybenzoate transferase activity |
2007-08-09 | Added | SYNONYM | para-hydroxybenzoate-polyprenyl diphosphate transferase activity |
2007-08-09 | Added | SYNONYM | para-hydroxybenzoate:polyprenyltransferase |
2007-08-09 | Deleted | SYNONYM | 4-hydroxybenzoate octaprenyltransferase activity |
2007-08-09 | Deleted | SYNONYM | PHB polyprenyl diphosphate transferase activity |
2004-04-19 | Added | SYNONYM | para-hydroxybenzoate transferase activity |
2004-04-19 | Added | SYNONYM | 4-HB polyprenyltransferase activity |
2004-04-19 | Added | SYNONYM | para-hydroxybenzoate:polyprenyltransferase |
2004-04-19 | Added | SYNONYM | para-hydroxybenzoate-polyprenyl diphosphate transferase activity |
2004-04-19 | Added | SYNONYM | 4-hydroxybenzoate octaprenyltransferase activity |
2004-04-19 | Added | SYNONYM | PHB polyprenyl diphosphate transferase activity |
2004-04-16 | Deleted | SYNONYM | para-hydroxybenzoate-polyprenyl diphosphate transferase activity |
2004-04-16 | Deleted | SYNONYM | para-hydroxybenzoate transferase activity |
2004-04-16 | Deleted | SYNONYM | para-hydroxybenzoate:polyprenyltransferase |
2004-04-16 | Deleted | SYNONYM | 4-HB polyprenyltransferase activity |
2004-04-16 | Deleted | SYNONYM | 4-hydroxybenzoate octaprenyltransferase activity |
2004-04-16 | Deleted | SYNONYM | PHB polyprenyl diphosphate transferase activity |
2003-12-16 | Updated | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. |
2003-10-27 | Added | SYNONYM | 4-HB polyprenyltransferase activity |
2003-10-27 | Added | SYNONYM | 4-hydroxybenzoate octaprenyltransferase activity |
2003-10-27 | Added | SYNONYM | PHB polyprenyl diphosphate transferase activity |
2003-10-27 | Added | SYNONYM | para-hydroxybenzoate transferase activity |
2003-10-27 | Added | SYNONYM | para-hydroxybenzoate-polyprenyl diphosphate transferase activity |
2003-10-27 | Added | SYNONYM | para-hydroxybenzoate:polyprenyltransferase |
2003-10-24 | Updated | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + pyrophosphate. |
2003-08-02 | Updated | DEFINITION | Catalysis of the reaction: farnesylfarnesylgeranyl-PP + para-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + pyrophosphate. |
2002-11-27 | Added | DEFINITION | Catalysis of the following reaction: farnesylfarnesylgeranyl-PP + para-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + pyrophosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0002094 (polyprenyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-08 | Deleted | XREF | Reactome:R-HSA-2162192 |
2024-07-12 | Added | XREF | RHEA:44504 |
2024-07-12 | Added | XREF | Reactome:R-HSA-2162192 |
2024-07-12 | Added | XREF | MetaCyc:RXN-11368 |
2024-07-12 | Deleted | XREF | RHEA:27782 |
2024-07-12 | Deleted | XREF | MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN |
2021-04-20 | Deleted | XREF | EC:2.5.1.- |
2021-04-20 | Added | XREF | EC:2.5.1.39 |
2021-01-04 | Added | XREF | EC:2.5.1.- |
2021-01-04 | Deleted | XREF | EC:2.5.1 |
2020-06-22 | Added | XREF | RHEA:27782 |
2016-10-03 | Added | XREF | EC:2.5.1 |
2016-10-03 | Deleted | XREF | EC:2.5.1.- |
2003-10-27 | Added | XREF | MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN |
2002-07-23 | Added | XREF | EC:2.5.1.- |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-09-19 | Added | SECONDARY | GO:0048043 (para-hydroxybenzoate transferase activity) |
2003-09-19 | Added | SECONDARY | GO:0048044 (para-hydroxybenzoate-polyprenyl diphosphate transferase activity) |
2002-07-23 | Added | SECONDARY | GO:0000043 (para-hydroxybenzoate:polyprenyltransferase) |
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