This term is obsolete.

GO:0008412 JSON

4-hydroxybenzoate polyprenyltransferase activity

Molecular Function

Definition (GO:0008412 GONUTS page)

Catalysis of the reaction: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate.

Secondary IDs

GO:0000043, GO:0048043, GO:0048044

18,811 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
para-hydroxybenzoate-polyprenyl diphosphate transferase activity exact
para-hydroxybenzoate transferase activity exact
PHB polyprenyl diphosphate transferase activity exact
para-hydroxybenzoate:polyprenyltransferase activity exact
4-hydroxybenzoate nonaprenyltransferase activity narrow
4-HB polyprenyltransferase activity exact

Ancestor Chart

Ancestor chart for GO:0008412
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I940 7227 Q8I940_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.5.1.39
MetaCyc RXN-11368
RHEA 44504

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:78396 4-hydroxy-3-polyprenylbenzoate
has_participant CHEBI CHEBI:17879 4-hydroxybenzoate
has_participant CHEBI CHEBI:58914 all-trans-polyprenyl diphosphate(3-)
has_participant CHEBI CHEBI:33019 diphosphate(3-)

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0002083 obsolete 4-hydroxybenzoate decaprenyltransferase activity replaced_by GO:0008412
GO:0047293 obsolete 4-hydroxybenzoate nonaprenyltransferase activity replaced_by GO:0008412

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008412 based on ALL annotations
The top 100 of 159 co-occurring terms
Co-occurring Term PR S% #Together #Compared
4-hydroxybenzoate polyprenyltransferase activity
10,589.16 100.00 18,713 18,713
obsolete polyprenyltransferase activity
3,444.92 10.96 2,654 8,158
ubiquinone biosynthetic process
917.73 8.66 18,614 214,777
prenyltransferase activity
669.23 6.28 17,040 269,624
transferase activity, transferring alkyl or aryl (other than methyl) groups
264.97 2.43 8,799 351,637
isoprenoid biosynthetic process
59.74 0.55 2,690 476,837
terpenoid biosynthetic process
41.86 0.36 845 213,780
transferase activity
27.13 0.26 18,229 7,114,403
mitochondrial inner membrane
13.14 0.12 3,730 3,005,356
plasma membrane
6.92 0.07 14,932 22,848,296
Totals 128073 113744926
No co-occurrence statistics for GO:0008412 based on MANUAL annotations
The top 22 of 22 co-occurring terms
Co-occurring Term PR S% #Together #Compared
4-hydroxybenzoate polyprenyltransferase activity
13,069.75 100.00 108 108
ubiquinone biosynthetic process
970.13 7.42 108 1,455
transferase activity, transferring alkyl or aryl (other than methyl) groups
478.16 1.60 3 82
mitochondrial inner membrane
173.80 1.33 99 7,445
austinol biosynthetic process
1,188.16 0.85 1 11
dehydroaustinol biosynthetic process
1,005.37 0.83 1 13
ubiquinone metabolic process
687.88 0.79 1 19
prenyltransferase activity
61.84 0.41 3 634
glycerol metabolic process
40.34 0.27 2 648
transcription by RNA polymerase III
36.20 0.24 2 722
Totals 357 218078

Change Log

Timestamp Action Category Detail
2024-12-13 Added RELATION is a GO:0004659 (prenyltransferase activity)
2024-12-13 Deleted RELATION is a GO:0002094 (obsolete polyprenyltransferase activity)
2024-11-23 Added SYNONYM 4-hydroxybenzoate nonaprenyltransferase activity
2024-11-08 Deleted XREF Reactome:R-HSA-2162192
2024-07-12 Added DEFINITION Catalysis of the reaction: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate.
2024-07-12 Deleted XREF MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN
2024-07-12 Added XREF RHEA:44504
2024-07-12 Added XREF Reactome:R-HSA-2162192
2024-07-12 Deleted DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
2024-07-12 Added XREF MetaCyc:RXN-11368
Timestamp Action Category Detail
2024-07-12 Updated TERM 4-hydroxybenzoate polyprenyltransferase activity
2003-03-19 Updated TERM 4-hydroxybenzoate octaprenyltransferase activity
2002-02-06 Updated TERM 4-hydroxybenzoate octaprenyltransferase
2001-04-03 Updated TERM 4-hydroxybenzoate octaprenyltransferase
2001-03-30 Added TERM 4-hydroxybenzoate octaprenyltransferase
Timestamp Action Category Detail
2024-11-23 Added SYNONYM 4-hydroxybenzoate nonaprenyltransferase activity
2024-07-12 Added DEFINITION Catalysis of the reaction: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate.
2024-07-12 Deleted DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
2010-09-15 Deleted DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
2010-09-15 Added DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
2008-05-13 Added DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
2007-11-08 Deleted SYNONYM para-hydroxybenzoate:polyprenyltransferase
2007-11-08 Added SYNONYM para-hydroxybenzoate:polyprenyltransferase activity
2007-10-06 Deleted SYNONYM 4-hydroxybenzoate octaprenyltransferase activity
2007-08-09 Added SYNONYM 4-hydroxybenzoate octaprenyltransferase activity
2007-08-09 Added SYNONYM 4-HB polyprenyltransferase activity
2007-08-09 Deleted SYNONYM para-hydroxybenzoate:polyprenyltransferase
2007-08-09 Deleted SYNONYM para-hydroxybenzoate-polyprenyl diphosphate transferase activity
2007-08-09 Deleted SYNONYM para-hydroxybenzoate transferase activity
2007-08-09 Deleted SYNONYM PHB polyprenyl diphosphate transferase activity
2007-08-09 Deleted SYNONYM 4-hydroxybenzoate octaprenyltransferase activity
2007-08-09 Deleted SYNONYM 4-HB polyprenyltransferase activity
2007-08-09 Added SYNONYM PHB polyprenyl diphosphate transferase activity
2007-08-09 Added SYNONYM para-hydroxybenzoate transferase activity
2007-08-09 Added SYNONYM para-hydroxybenzoate-polyprenyl diphosphate transferase activity
2007-08-09 Added SYNONYM para-hydroxybenzoate:polyprenyltransferase
2004-04-19 Added SYNONYM 4-HB polyprenyltransferase activity
2004-04-19 Added SYNONYM para-hydroxybenzoate:polyprenyltransferase
2004-04-19 Added SYNONYM para-hydroxybenzoate-polyprenyl diphosphate transferase activity
2004-04-19 Added SYNONYM para-hydroxybenzoate transferase activity
2004-04-19 Added SYNONYM PHB polyprenyl diphosphate transferase activity
2004-04-19 Added SYNONYM 4-hydroxybenzoate octaprenyltransferase activity
2004-04-16 Deleted SYNONYM para-hydroxybenzoate:polyprenyltransferase
2004-04-16 Deleted SYNONYM 4-hydroxybenzoate octaprenyltransferase activity
2004-04-16 Deleted SYNONYM PHB polyprenyl diphosphate transferase activity
2004-04-16 Deleted SYNONYM para-hydroxybenzoate transferase activity
2004-04-16 Deleted SYNONYM para-hydroxybenzoate-polyprenyl diphosphate transferase activity
2004-04-16 Deleted SYNONYM 4-HB polyprenyltransferase activity
2003-12-16 Updated DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
2003-10-27 Added SYNONYM PHB polyprenyl diphosphate transferase activity
2003-10-27 Added SYNONYM para-hydroxybenzoate transferase activity
2003-10-27 Added SYNONYM para-hydroxybenzoate-polyprenyl diphosphate transferase activity
2003-10-27 Added SYNONYM 4-hydroxybenzoate octaprenyltransferase activity
2003-10-27 Added SYNONYM 4-HB polyprenyltransferase activity
2003-10-27 Added SYNONYM para-hydroxybenzoate:polyprenyltransferase
2003-10-24 Updated DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + pyrophosphate.
2003-08-02 Updated DEFINITION Catalysis of the reaction: farnesylfarnesylgeranyl-PP + para-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + pyrophosphate.
2002-11-27 Added DEFINITION Catalysis of the following reaction: farnesylfarnesylgeranyl-PP + para-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + pyrophosphate.
Timestamp Action Category Detail
2024-12-13 Added RELATION is a GO:0004659 (prenyltransferase activity)
2024-12-13 Deleted RELATION is a GO:0002094 (obsolete polyprenyltransferase activity)
2008-04-01 Updated RELATION is a GO:0002094 (obsolete polyprenyltransferase activity)
Timestamp Action Category Detail
2024-11-08 Deleted XREF Reactome:R-HSA-2162192
2024-07-12 Deleted XREF MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN
2024-07-12 Added XREF RHEA:44504
2024-07-12 Added XREF Reactome:R-HSA-2162192
2024-07-12 Added XREF MetaCyc:RXN-11368
2024-07-12 Deleted XREF RHEA:27782
2021-04-20 Added XREF EC:2.5.1.39
2021-04-20 Deleted XREF EC:2.5.1.-
2021-01-04 Deleted XREF EC:2.5.1
2021-01-04 Added XREF EC:2.5.1.-
2020-06-22 Added XREF RHEA:27782
2016-10-03 Added XREF EC:2.5.1
2016-10-03 Deleted XREF EC:2.5.1.-
2003-10-27 Added XREF MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN
2002-07-23 Added XREF EC:2.5.1.-
Timestamp Action Category Detail
2003-09-19 Added SECONDARY GO:0048044 (para-hydroxybenzoate-polyprenyl diphosphate transferase activity)
2003-09-19 Added SECONDARY GO:0048043 (para-hydroxybenzoate transferase activity)
2002-07-23 Added SECONDARY GO:0000043 (para-hydroxybenzoate:polyprenyltransferase)
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