GO:0008469
JSON
histone arginine N-methyltransferase activity
Molecular Function
Definition (GO:0008469 GONUTS page)
Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine. PMID:8002954
Secondary IDs
GO:0016276
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity | exact |
S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity | exact |
histone-arginine N-methylase activity | exact |
histone-arginine N-methyltransferase activity | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A8I5YBY9 | 10116 | A0A8I5YBY9_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AGH5 | 10116 | A0A8I6AGH5_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A2VDP2 | 9913 | PCMD1_BOVIN | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6JFH4 | 10116 | A6JFH4_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JFH5 | 10116 | A6JFH5_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7XRZ1 | 227321 | TDIE_EMENI | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17704773 | |
NOT-qualified manual | protein | D3Z930 | 10116 | D3Z930_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A629 | 10116 | D4A629_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
RHEA | 48108 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:59789 | S-adenosyl-L-methionine zwitterion |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:57856 | S-adenosyl-L-homocysteine zwitterion |
has_participant | CHEBI | CHEBI:88221 | N(omega),N('omega)-dimethyl-L-arginine(1+) residue |
has_participant | CHEBI | CHEBI:29965 | L-argininium residue |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008469 based on ALL annotations
The top 100 of 239 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
|
40,481.08 | 100.00 | 4,895 | 4,895 |
|
5,790.79 | 14.30 | 4,895 | 34,219 |
|
4,128.38 | 6.41 | 720 | 7,060 |
|
4,159.51 | 6.06 | 631 | 6,141 |
|
4,054.85 | 5.84 | 601 | 6,000 |
|
4,054.85 | 5.84 | 601 | 6,000 |
|
3,996.24 | 5.79 | 601 | 6,088 |
|
3,995.59 | 5.79 | 601 | 6,089 |
|
3,288.11 | 5.50 | 713 | 8,778 |
|
3,100.83 | 4.95 | 601 | 7,846 |
Totals | 48764 | 45611145 |
No co-occurrence statistics for GO:0008469 based on MANUAL annotations
The top 100 of 137 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
|
11,202.64 | 100.00 | 126 | 126 |
|
3,640.86 | 8.50 | 13 | 40 |
|
6,401.51 | 6.06 | 8 | 14 |
|
829.83 | 3.98 | 10 | 135 |
|
11,202.64 | 3.97 | 5 | 5 |
|
826.42 | 3.77 | 9 | 122 |
|
1,120.26 | 3.70 | 7 | 70 |
|
2,667.30 | 3.52 | 5 | 21 |
|
538.59 | 3.09 | 10 | 208 |
|
781.58 | 2.91 | 6 | 86 |
Totals | 587 | 66899 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-08-16 | Added | XREF | RHEA:48108 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-10-28 | Added | XREF | Reactome:R-HSA-5216234 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-24 | Updated | TERM | histone arginine N-methyltransferase activity |
2003-03-19 | Updated | TERM | histone-arginine N-methyltransferase activity |
2002-02-06 | Updated | TERM | histone-arginine N-methyltransferase |
2001-04-03 | Updated | TERM | histone-arginine N-methyltransferase |
2001-03-30 | Added | TERM | histone-arginine N-methyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-24 | Added | SYNONYM | histone-arginine N-methyltransferase activity |
2022-07-18 | Deleted | SYNONYM | histone protein methylase I |
2022-07-18 | Deleted | SYNONYM | nuclear protein (histone) N-methyltransferase activity |
2022-07-18 | Deleted | SYNONYM | histone methyltransferase activity |
2022-07-18 | Deleted | SYNONYM | histone protein methylase activity |
2022-07-18 | Deleted | SYNONYM | protein methylase I activity |
2010-10-08 | Deleted | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + histone-arginine = S-adenosyl-L-homocysteine + histone-N-methyl-arginine. |
2010-10-08 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine. |
2009-07-23 | Added | SYNONYM | histone-arginine N-methylase activity |
2009-01-31 | Added | SYNONYM | histone methyltransferase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + histone-arginine = S-adenosyl-L-homocysteine + histone-N-methyl-arginine. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + histone-arginine = S-adenosyl-L-homocysteine + histone-N-methyl-arginine. |
2007-11-08 | Added | SYNONYM | histone protein methylase I |
2007-11-08 | Added | SYNONYM | nuclear protein (histone) N-methyltransferase activity |
2007-11-08 | Added | SYNONYM | S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity |
2007-11-08 | Added | SYNONYM | S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity |
2007-09-06 | Added | SYNONYM | histone protein methylase activity |
2007-09-06 | Added | SYNONYM | protein methylase I activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + histone-arginine = S-adenosyl-L-homocysteine + histone-N-methyl-arginine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-02-17 | Deleted | RELATION | part of GO:0034969 (obsolete histone arginine methylation) |
2010-07-16 | Added | RELATION | part of GO:0034969 (obsolete histone arginine methylation) |
2008-04-01 | Updated | RELATION | is a GO:0042054 (histone methyltransferase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016274 (protein-arginine N-methyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-08-16 | Added | XREF | RHEA:48108 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-11-01 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-10-28 | Added | XREF | Reactome:R-HSA-5216234 |
2023-10-28 | Added | XREF | Reactome:R-HSA-8937113 |
2023-10-28 | Added | XREF | Reactome:R-HSA-5661117 |
2023-10-28 | Added | XREF | Reactome:R-HSA-8936608 |
2023-10-28 | Added | XREF | Reactome:R-HSA-5205799 |
2023-10-28 | Added | XREF | Reactome:R-HSA-8937022 |
2023-10-28 | Added | XREF | Reactome:R-HSA-5205861 |
2023-10-28 | Added | XREF | Reactome:R-HSA-8936584 |
2023-10-23 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-10-23 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-10-23 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-10-23 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-10-23 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-10-23 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-10-23 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-10-23 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-10-10 | Added | XREF | Reactome:R-HSA-8937022 |
2023-10-10 | Added | XREF | Reactome:R-HSA-8936584 |
2023-10-10 | Added | XREF | Reactome:R-HSA-5205861 |
2023-10-10 | Added | XREF | Reactome:R-HSA-5205799 |
2023-10-10 | Added | XREF | Reactome:R-HSA-5661117 |
2023-10-10 | Added | XREF | Reactome:R-HSA-8937113 |
2023-10-10 | Added | XREF | Reactome:R-HSA-5216234 |
2023-10-10 | Added | XREF | Reactome:R-HSA-8936608 |
2023-08-28 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-08-28 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-08-28 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-08-28 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-08-28 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-08-28 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-08-28 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-08-28 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-08-14 | Added | XREF | Reactome:R-HSA-5216234 |
2023-08-14 | Added | XREF | Reactome:R-HSA-8937113 |
2023-08-14 | Added | XREF | Reactome:R-HSA-5661117 |
2023-08-14 | Added | XREF | Reactome:R-HSA-8936608 |
2023-08-14 | Added | XREF | Reactome:R-HSA-5205799 |
2023-08-14 | Added | XREF | Reactome:R-HSA-5205861 |
2023-08-14 | Added | XREF | Reactome:R-HSA-8936584 |
2023-08-14 | Added | XREF | Reactome:R-HSA-8937022 |
2023-08-12 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-08-12 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-08-12 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-08-12 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-08-12 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-08-12 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-08-12 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-08-12 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-08-11 | Added | XREF | Reactome:R-HSA-5216234 |
2023-08-11 | Added | XREF | Reactome:R-HSA-8937113 |
2023-08-11 | Added | XREF | Reactome:R-HSA-5661117 |
2023-08-11 | Added | XREF | Reactome:R-HSA-8936608 |
2023-08-11 | Added | XREF | Reactome:R-HSA-5205799 |
2023-08-11 | Added | XREF | Reactome:R-HSA-5205861 |
2023-08-11 | Added | XREF | Reactome:R-HSA-8936584 |
2023-08-11 | Added | XREF | Reactome:R-HSA-8937022 |
2023-07-26 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-07-26 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-07-26 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-07-26 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-07-26 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-07-26 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-07-26 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-07-26 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-07-24 | Added | XREF | Reactome:R-HSA-8936584 |
2023-07-24 | Added | XREF | Reactome:R-HSA-5205861 |
2023-07-24 | Added | XREF | Reactome:R-HSA-5205799 |
2023-07-24 | Added | XREF | Reactome:R-HSA-8936608 |
2023-07-24 | Added | XREF | Reactome:R-HSA-5661117 |
2023-07-24 | Added | XREF | Reactome:R-HSA-8937113 |
2023-07-24 | Added | XREF | Reactome:R-HSA-5216234 |
2023-07-24 | Added | XREF | Reactome:R-HSA-8937022 |
2023-07-14 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-07-14 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-07-14 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-07-14 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-07-14 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-07-14 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-07-14 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-07-14 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-07-12 | Added | XREF | Reactome:R-HSA-5216234 |
2023-07-12 | Added | XREF | Reactome:R-HSA-8937113 |
2023-07-12 | Added | XREF | Reactome:R-HSA-5661117 |
2023-07-12 | Added | XREF | Reactome:R-HSA-8936608 |
2023-07-12 | Added | XREF | Reactome:R-HSA-5205799 |
2023-07-12 | Added | XREF | Reactome:R-HSA-5205861 |
2023-07-12 | Added | XREF | Reactome:R-HSA-8937022 |
2023-07-12 | Added | XREF | Reactome:R-HSA-8936584 |
2023-07-10 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-07-10 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-07-10 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-07-10 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-07-10 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-07-10 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-07-10 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-07-10 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-07-08 | Added | XREF | Reactome:R-HSA-8936584 |
2023-07-08 | Added | XREF | Reactome:R-HSA-5205861 |
2023-07-08 | Added | XREF | Reactome:R-HSA-5216234 |
2023-07-08 | Added | XREF | Reactome:R-HSA-8937113 |
2023-07-08 | Added | XREF | Reactome:R-HSA-5661117 |
2023-07-08 | Added | XREF | Reactome:R-HSA-8936608 |
2023-07-08 | Added | XREF | Reactome:R-HSA-5205799 |
2023-07-08 | Added | XREF | Reactome:R-HSA-8937022 |
2023-06-24 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-06-24 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-06-24 | Deleted | XREF | Reactome:R-HSA-5216234 |
2023-06-24 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-06-24 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-06-24 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-06-24 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-06-24 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-06-18 | Added | XREF | Reactome:R-HSA-5205799 |
2023-06-18 | Added | XREF | Reactome:R-HSA-5216234 |
2023-06-18 | Added | XREF | Reactome:R-HSA-8937113 |
2023-06-18 | Added | XREF | Reactome:R-HSA-5661117 |
2023-06-18 | Added | XREF | Reactome:R-HSA-8936608 |
2023-06-18 | Added | XREF | Reactome:R-HSA-5205861 |
2023-06-18 | Added | XREF | Reactome:R-HSA-8936584 |
2023-06-18 | Added | XREF | Reactome:R-HSA-8937022 |
2023-06-13 | Deleted | XREF | Reactome:R-HSA-8936584 |
2023-06-13 | Deleted | XREF | Reactome:R-HSA-8937022 |
2023-06-13 | Deleted | XREF | Reactome:R-HSA-5205799 |
2023-06-13 | Deleted | XREF | Reactome:R-HSA-5205861 |
2023-06-13 | Deleted | XREF | Reactome:R-HSA-8936608 |
2023-06-13 | Deleted | XREF | Reactome:R-HSA-5661117 |
2023-06-13 | Deleted | XREF | Reactome:R-HSA-8937113 |
2023-06-13 | Deleted | XREF | Reactome:R-HSA-5216234 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5205799 |
2019-04-01 | Added | XREF | Reactome:R-HSA-8937113 |
2019-04-01 | Added | XREF | Reactome:R-HSA-8936584 |
2019-04-01 | Added | XREF | Reactome:R-HSA-8936608 |
2019-04-01 | Added | XREF | Reactome:R-HSA-8937022 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5205861 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5661117 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5205799 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-8936608 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5205861 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5216234 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-8937022 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-8936584 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5216234 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5661117 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-8937113 |
2018-12-11 | Added | XREF | reactome:R-HSA-8936584 |
2018-12-11 | Added | XREF | reactome:R-HSA-5205861 |
2018-12-11 | Added | XREF | reactome:R-HSA-5205799 |
2018-12-11 | Added | XREF | reactome:R-HSA-5661117 |
2018-12-11 | Added | XREF | reactome:R-HSA-5216234 |
2018-12-11 | Added | XREF | reactome:R-HSA-8937113 |
2018-12-11 | Added | XREF | reactome:R-HSA-8936608 |
2018-12-11 | Added | XREF | reactome:R-HSA-8937022 |
2016-11-28 | Deleted | XREF | EC:2.1.1.125 |
2016-11-28 | Deleted | XREF | MetaCyc:2.1.1.125-RXN |
2003-10-27 | Added | XREF | MetaCyc:2.1.1.125-RXN |
2001-03-30 | Added | XREF | EC:2.1.1.125 |
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link