GO:0008521
JSON
acetyl-CoA transmembrane transporter activity
Molecular Function
Definition (GO:0008521 GONUTS page)
Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
acetyl-CoA transporter activity | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0008521
Child Term | Relationship to GO:0008521 |
---|---|
acetyl-CoA:CoA antiporter activity
|
is_a |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR024371 | Acetyl-coenzyme A transporter 1-like |
Reactome | R-HSA-5649742 | |
Reactome | R-HSA-727759 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:57288 | acetyl-CoA(4-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008521 based on ALL annotations
The top 100 of 160 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
acetyl-CoA transmembrane transporter activity
|
27,603.91 | 100.00 | 7,062 | 7,062 |
acetyl-CoA transmembrane transport
|
27,603.90 | 98.71 | 6,971 | 6,971 |
acetyl-CoA transport
|
27,603.90 | 1.29 | 91 | 91 |
central nervous system neuron axonogenesis
|
3,072.89 | 0.78 | 59 | 530 |
NAD transmembrane transport
|
536.06 | 0.78 | 91 | 4,686 |
NAD transmembrane transporter activity
|
449.61 | 0.72 | 91 | 5,587 |
negative regulation of BMP signaling pathway
|
58.30 | 0.17 | 59 | 27,933 |
protein homodimerization activity
|
13.88 | 0.05 | 103 | 204,841 |
mitochondrial outer membrane
|
12.38 | 0.04 | 92 | 205,153 |
threonyl-tRNA aminoacylation
|
8.00 | 0.03 | 18 | 62,139 |
Totals | 22338 | 88587089 |
No co-occurrence statistics for GO:0008521 based on MANUAL annotations
The top 16 of 16 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
acetyl-CoA transmembrane transporter activity
|
184,542.70 | 100.00 | 7 | 7 |
acetyl-CoA transmembrane transport
|
184,542.72 | 57.14 | 4 | 4 |
NAD transmembrane transporter activity
|
2,551.28 | 1.36 | 3 | 217 |
mitochondrial outer membrane
|
166.01 | 0.09 | 3 | 3,335 |
mitochondrial inner membrane
|
79.15 | 0.04 | 3 | 6,995 |
protein homodimerization activity
|
69.39 | 0.04 | 2 | 5,319 |
endoplasmic reticulum membrane
|
32.96 | 0.02 | 3 | 16,799 |
transmembrane transporter activity
|
31.09 | 0.02 | 2 | 11,872 |
Golgi membrane
|
22.09 | 0.01 | 1 | 8,354 |
transmembrane transport
|
13.02 | 0.01 | 1 | 14,169 |
Totals | 38 | 549887 |
Change Log
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- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-08-20 | Deleted | RELATION | is a GO:0071077 (adenosine 3',5'-bisphosphate transmembrane transporter activity) |
2024-08-20 | Added | RELATION | is a GO:0015605 (organophosphate ester transmembrane transporter activity) |
2024-08-20 | Added | RELATION | is a GO:0015932 (nucleobase-containing compound transmembrane transporter activity) |
2020-05-08 | Deleted | RELATION | is a GO:0051185 (obsolete coenzyme transmembrane transporter activity) |
2019-05-04 | Added | XREF | Reactome:R-HSA-5649742 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5649742 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5649742 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5649742 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5649742 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5649742 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-11-06 | Updated | TERM | acetyl-CoA transmembrane transporter activity |
2003-03-19 | Updated | TERM | acetyl-CoA transporter activity |
2002-02-06 | Updated | TERM | acetyl-CoA transporter |
2001-04-03 | Updated | TERM | acetyl-CoA transporter |
2001-03-30 | Added | TERM | acetyl-CoA transporter |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-11-06 | Added | DEFINITION | Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2017-11-06 | Deleted | DEFINITION | Enables the directed movement of acetyl-CoA into, out of or within a cell, or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2017-11-06 | Added | SYNONYM | acetyl-CoA transporter activity |
2010-09-15 | Added | DEFINITION | Enables the directed movement of acetyl-CoA into, out of or within a cell, or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2010-09-15 | Deleted | DEFINITION | Enables the directed movement of acetyl-CoA into, out of, within or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2008-05-13 | Added | DEFINITION | Enables the directed movement of acetyl-CoA into, out of, within or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2008-05-12 | Deleted | DEFINITION | Enables the directed movement of acetyl-CoA into, out of, within or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2004-03-13 | Updated | DEFINITION | Enables the directed movement of acetyl-CoA into, out of, within or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2003-10-18 | Updated | DEFINITION | Enables the directed movement of acetyl-CoA into, out of, within or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (eg. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2003-04-24 | Updated | DEFINITION | Enables the directed movement of acetyl-CoA into, out of, within or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e. g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
2003-03-26 | Added | DEFINITION | Enables the directed movement of acetyl-CoA into, out of, within or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-08-20 | Deleted | RELATION | is a GO:0071077 (adenosine 3',5'-bisphosphate transmembrane transporter activity) |
2024-08-20 | Added | RELATION | is a GO:0015605 (organophosphate ester transmembrane transporter activity) |
2024-08-20 | Added | RELATION | is a GO:0015932 (nucleobase-containing compound transmembrane transporter activity) |
2020-05-08 | Deleted | RELATION | is a GO:0051185 (obsolete coenzyme transmembrane transporter activity) |
2018-06-04 | Added | RELATION | is a GO:0042887 (amide transmembrane transporter activity) |
2018-06-04 | Added | RELATION | is a GO:0071077 (adenosine 3',5'-bisphosphate transmembrane transporter activity) |
2017-11-06 | Added | RELATION | is a GO:1901682 (sulfur compound transmembrane transporter activity) |
2017-11-06 | Added | RELATION | is a GO:0008514 (organic anion transmembrane transporter activity) |
2010-06-15 | Added | RELATION | part of GO:0015876 (acetyl-CoA transport) |
2010-06-14 | Deleted | RELATION | part of GO:0015876 (acetyl-CoA transport) |
2010-06-08 | Added | RELATION | part of GO:0015876 (acetyl-CoA transport) |
2008-04-01 | Updated | RELATION | is a GO:0051185 (obsolete coenzyme transmembrane transporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-05-04 | Added | XREF | Reactome:R-HSA-5649742 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5649742 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5649742 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5649742 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5649742 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5649742 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-727759 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5649742 |
2019-04-01 | Added | XREF | Reactome:R-HSA-727759 |
2018-12-11 | Added | XREF | reactome:R-HSA-727759 |
Timestamp | Action | Category | Detail |
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