GO:0008531
JSON
riboflavin kinase activity
Molecular Function
Definition (GO:0008531 GONUTS page)
Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H+.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
riboflavin kinase (phosphorylating) | related |
riboflavine kinase activity | related |
flavokinase activity | related |
FK | related |
ATP:riboflavin 5'-phosphotransferase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A1L8END5 | 8355 | A0A1L8END5_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8EV37 | 8355 | A0A1L8EV37_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I3Q0M1 | 9615 | A0A8I3Q0M1_CANLF | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I6AKN3 | 10116 | A0A8I6AKN3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6ALM9 | 10116 | A0A8I6ALM9_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6GLX5 | 10116 | A0A8I6GLX5_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8J0TR01 | 8355 | A0A8J0TR01_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8J0TZJ2 | 8355 | A0A8J0TZJ2_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8M2B232 | 7955 | A0A8M2B232_DANRE | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.1.26 | |
InterPro | IPR002606 | Riboflavin kinase, bacterial |
InterPro | IPR015865 | Riboflavin kinase domain, bacterial/eukaryotic |
InterPro | IPR023465 | Riboflavin kinase domain superfamily |
InterPro | IPR023470 | Riboflavin kinase, archaeal |
KEGG_REACTION | R00549 | |
MetaCyc | RIBOFLAVINKIN-RXN | |
RHEA | 14357 | |
Reactome | R-HSA-196964 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57986 | riboflavin(1-) |
has_participant | CHEBI | CHEBI:30616 | ATP(4-) |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:456216 | ADP(3-) |
has_participant | CHEBI | CHEBI:58210 | FMN(3-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008531 based on ALL annotations
The top 100 of 361 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
riboflavin kinase activity
|
3,859.43 | 100.00 | 51,343 | 51,343 |
FMN biosynthetic process
|
3,859.43 | 97.47 | 50,046 | 50,046 |
riboflavin metabolic process
|
3,839.56 | 91.03 | 46,959 | 47,202 |
FMN adenylyltransferase activity
|
3,263.60 | 69.06 | 40,571 | 47,978 |
FAD biosynthetic process
|
3,279.55 | 67.83 | 39,572 | 46,569 |
riboflavin biosynthetic process
|
584.63 | 15.15 | 51,298 | 338,644 |
nucleotidyltransferase activity
|
81.50 | 2.10 | 40,821 | 1,933,012 |
kinase activity
|
33.16 | 0.86 | 45,960 | 5,349,025 |
phosphotransferase activity, alcohol group as acceptor
|
32.94 | 0.64 | 1,303 | 152,679 |
glycerol biosynthetic process
|
500.52 | 0.39 | 204 | 1,573 |
Totals | 433964 | 116864455 |
No co-occurrence statistics for GO:0008531 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
riboflavin kinase activity
|
7,429.12 | 100.00 | 190 | 190 |
FMN biosynthetic process
|
7,429.12 | 97.37 | 185 | 185 |
riboflavin metabolic process
|
6,985.59 | 93.56 | 189 | 201 |
flavin adenine dinucleotide biosynthetic process
|
2,476.37 | 2.02 | 4 | 12 |
reactive oxygen species metabolic process
|
124.86 | 0.94 | 4 | 238 |
FMN adenylyltransferase activity
|
88.44 | 0.56 | 2 | 168 |
positive regulation of NAD(P)H oxidase activity
|
1,061.30 | 0.51 | 1 | 7 |
riboflavin biosynthetic process
|
42.37 | 0.42 | 3 | 526 |
apoptotic process
|
20.87 | 0.25 | 5 | 1,780 |
mitochondrion
|
8.50 | 0.11 | 56 | 48,955 |
Totals | 656 | 618873 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+). |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H+. |
2020-10-08 | Deleted | SYNONYM | riboflavin kinase (phosphorylating) |
2020-10-08 | Deleted | SYNONYM | ATP:riboflavin 5'-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | riboflavin kinase (phosphorylating) |
2020-10-08 | Added | SYNONYM | flavokinase activity |
2020-10-08 | Added | SYNONYM | ATP:riboflavin 5'-phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | riboflavine kinase activity |
2020-10-08 | Deleted | SYNONYM | flavokinase activity |
2020-10-08 | Added | SYNONYM | riboflavine kinase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | riboflavin kinase activity |
2002-02-06 | Updated | TERM | riboflavin kinase |
2001-04-03 | Updated | TERM | riboflavin kinase |
2001-03-30 | Added | TERM | riboflavin kinase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+). |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H+. |
2020-10-08 | Deleted | SYNONYM | riboflavin kinase (phosphorylating) |
2020-10-08 | Deleted | SYNONYM | ATP:riboflavin 5'-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | riboflavin kinase (phosphorylating) |
2020-10-08 | Added | SYNONYM | flavokinase activity |
2020-10-08 | Added | SYNONYM | ATP:riboflavin 5'-phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | riboflavine kinase activity |
2020-10-08 | Deleted | SYNONYM | flavokinase activity |
2020-10-08 | Added | SYNONYM | riboflavine kinase activity |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+). |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN. |
2007-11-08 | Added | SYNONYM | riboflavine kinase activity |
2007-11-08 | Added | SYNONYM | FK |
2007-11-08 | Added | SYNONYM | riboflavin kinase (phosphorylating) |
2007-11-08 | Added | SYNONYM | ATP:riboflavin 5'-phosphotransferase activity |
2007-09-06 | Added | SYNONYM | flavokinase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: ATP + riboflavin = ADP + FMN. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016773 (phosphotransferase activity, alcohol group as acceptor) |
2008-04-01 | Updated | RELATION | is a GO:0016301 (kinase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R00549 |
2019-06-20 | Added | XREF | KEGG_REACTION:R00549 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-196964 |
2019-04-01 | Added | XREF | Reactome:R-HSA-196964 |
2018-12-11 | Added | XREF | reactome:R-HSA-196964 |
2018-07-13 | Deleted | XREF | RHEA:14360 |
2018-07-13 | Added | XREF | RHEA:14357 |
2010-10-11 | Added | XREF | KEGG:R00549 |
2010-10-11 | Added | XREF | RHEA:14360 |
2003-10-27 | Added | XREF | MetaCyc:RIBOFLAVINKIN-RXN |
2001-03-30 | Added | XREF | EC:2.7.1.26 |
Timestamp | Action | Category | Detail |
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