GO:0008686
JSON
3,4-dihydroxy-2-butanone-4-phosphate synthase activity
Molecular Function
Definition (GO:0008686 GONUTS page)
Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H+.
Ancestor Chart
Ancestor chart for GO:0008686
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q946J8 | 3702 | LHP1_ARATH | GO:0008686 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23203051 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 4.1.99.12 | |
InterPro | IPR000422 | 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB |
KEGG_REACTION | R07281 | |
MetaCyc | DIOHBUTANONEPSYN-RXN | |
RHEA | 18457 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:58830 | (2S)-2-hydroxy-3-oxobutyl phosphate(2-) |
has_participant | CHEBI | CHEBI:15740 | formate |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:58121 | D-ribulose 5-phosphate(2-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008686 based on ALL annotations
The top 100 of 237 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
3,4-dihydroxy-2-butanone-4-phosphate synthase activity
|
3,920.10 | 100.00 | 49,728 | 49,728 |
GTP cyclohydrolase II activity
|
2,774.24 | 59.95 | 39,626 | 55,993 |
riboflavin biosynthetic process
|
586.62 | 14.96 | 49,692 | 332,069 |
manganese ion binding
|
276.43 | 6.81 | 33,210 | 470,951 |
mitochondrial intermembrane space
|
73.61 | 1.22 | 1,665 | 88,673 |
catalytic activity
|
42.94 | 1.10 | 49,277 | 4,498,570 |
magnesium ion binding
|
41.30 | 1.05 | 33,214 | 3,152,949 |
lyase activity
|
35.16 | 0.89 | 40,244 | 4,487,410 |
GTP binding
|
35.36 | 0.89 | 22,471 | 2,491,223 |
zinc ion binding
|
16.30 | 0.41 | 19,298 | 4,641,088 |
Totals | 463199 | 104209317 |
No co-occurrence statistics for GO:0008686 based on MANUAL annotations
The top 32 of 32 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
3,4-dihydroxy-2-butanone-4-phosphate synthase activity
|
7,643.78 | 100.00 | 169 | 169 |
riboflavin biosynthetic process
|
2,573.61 | 33.53 | 167 | 496 |
GTP cyclohydrolase II activity
|
458.63 | 1.39 | 3 | 50 |
chloroplast
|
82.80 | 1.07 | 96 | 8,862 |
mitochondrial intermembrane space
|
87.42 | 1.03 | 16 | 1,399 |
shoot system morphogenesis
|
764.38 | 0.56 | 1 | 10 |
vernalization response
|
449.63 | 0.54 | 1 | 17 |
photoperiodism
|
159.25 | 0.46 | 1 | 48 |
photoperiodism, flowering
|
152.88 | 0.46 | 1 | 50 |
multidimensional cell growth
|
66.47 | 0.35 | 1 | 115 |
Totals | 552 | 402393 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+). |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H+. |
2019-06-20 | Deleted | XREF | KEGG:R07281 |
2019-06-20 | Added | XREF | KEGG_REACTION:R07281 |
2018-07-13 | Deleted | XREF | RHEA:18460 |
2018-07-13 | Added | XREF | RHEA:18457 |
2010-10-11 | Added | XREF | RHEA:18460 |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+). |
2010-10-11 | Added | XREF | KEGG:R07281 |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: ribulose-5-phosphate = 3,4-dihydroxy-2-butanone-4-phosphate + formate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-10-29 | Updated | TERM | 3,4-dihydroxy-2-butanone-4-phosphate synthase activity |
2003-03-19 | Updated | TERM | 3,4 dihydroxy-2-butanone-4-phosphate synthase activity |
2002-02-06 | Updated | TERM | 3,4 dihydroxy-2-butanone-4-phosphate synthase |
2001-04-03 | Updated | TERM | 3,4 dihydroxy-2-butanone-4-phosphate synthase |
2001-03-30 | Added | TERM | 3,4 dihydroxy-2-butanone-4-phosphate synthase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+). |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H+. |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+). |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: ribulose-5-phosphate = 3,4-dihydroxy-2-butanone-4-phosphate + formate. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ribulose-5-phosphate = 3,4-dihydroxy-2-butanone-4-phosphate + formate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ribulose-5-phosphate = 3,4-dihydroxy-2-butanone-4-phosphate + formate. |
2003-10-30 | Updated | DEFINITION | Catalysis of the reaction: ribulose-5-phosphate = 3,4-dihydroxy-2-butanone-4-phosphate + formate. |
2003-03-26 | Added | DEFINITION | Catalysis of the reaction: ribulose-5-phosphate = 3,4-dihydroxy-2-butanone-4-P + formate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016830 (carbon-carbon lyase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R07281 |
2019-06-20 | Added | XREF | KEGG_REACTION:R07281 |
2018-07-13 | Deleted | XREF | RHEA:18460 |
2018-07-13 | Added | XREF | RHEA:18457 |
2010-10-11 | Added | XREF | RHEA:18460 |
2010-10-11 | Added | XREF | KEGG:R07281 |
2007-12-02 | Added | XREF | EC:4.1.99.12 |
2003-10-27 | Added | XREF | MetaCyc:DIOHBUTANONEPSYN-RXN |
Timestamp | Action | Category | Detail |
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