GO:0008697
JSON
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity
Molecular Function
Definition (GO:0008697 GONUTS page)
Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity | related |
5-keto-4-deoxyuronate isomerase activity | related |
4-deoxy-L-threo-5-hexulose uronate isomerase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 5.3.1.17 | |
InterPro | IPR007045 | 5-keto 4-deoxyuronate isomerase |
KEGG_REACTION | R04383 | |
MetaCyc | 5.3.1.17-RXN | |
RHEA | 23896 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:29071 | 3-deoxy-D-glycero-hexo-2,5-diulosonate |
has_participant | CHEBI | CHEBI:17117 | 5-dehydro-4-deoxy-D-glucuronate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008697 based on ALL annotations
The top 37 of 37 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity
|
24,194.96 | 100.00 | 8,057 | 8,057 |
D-glucuronate catabolic process
|
4,005.14 | 16.53 | 7,979 | 48,201 |
D-galacturonate catabolic process
|
3,357.77 | 13.86 | 7,979 | 57,494 |
pectin catabolic process
|
2,661.76 | 10.99 | 7,980 | 72,537 |
isomerase activity
|
61.08 | 0.25 | 8,036 | 3,183,067 |
zinc ion binding
|
37.10 | 0.15 | 7,116 | 4,641,088 |
intramolecular oxidoreductase activity, interconverting aldoses and ketoses
|
27.21 | 0.10 | 53 | 47,129 |
lactose metabolic process
|
15.42 | 0.04 | 8 | 12,553 |
metal ion binding
|
8.12 | 0.03 | 7,980 | 23,771,070 |
rhamnose transmembrane transporter activity
|
6.45 | 0.01 | 1 | 3,752 |
Totals | 55318 | 215354771 |
No co-occurrence statistics for GO:0008697 based on MANUAL annotations
The top 10 of 10 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity
|
161,474.88 | 100.00 | 8 | 8 |
D-glucuronate catabolic process
|
28,082.59 | 17.39 | 8 | 46 |
D-galacturonate catabolic process
|
27,485.09 | 17.02 | 8 | 47 |
metal ion binding
|
1,246.91 | 0.77 | 8 | 1,036 |
glucose-6-phosphate isomerase activity
|
776.32 | 0.47 | 1 | 208 |
protein homodimerization activity
|
30.36 | 0.02 | 1 | 5,319 |
zinc ion binding
|
25.51 | 0.02 | 1 | 6,330 |
identical protein binding
|
18.39 | 0.01 | 1 | 8,780 |
protein binding
|
3.86 | 0.00 | 1 | 41,817 |
cytosol
|
1.92 | 0.00 | 1 | 84,217 |
Totals | 38 | 147808 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | 4-deoxy-L-threo-5-hexulose uronate isomerase activity |
2020-10-08 | Deleted | SYNONYM | 4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity |
2020-10-08 | Deleted | SYNONYM | 5-keto-4-deoxyuronate isomerase activity |
2020-10-08 | Added | SYNONYM | 4-deoxy-L-threo-5-hexulose uronate isomerase activity |
2020-10-08 | Added | SYNONYM | 4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity |
2020-10-08 | Added | SYNONYM | 5-keto-4-deoxyuronate isomerase activity |
2019-06-20 | Deleted | XREF | KEGG:R04383 |
2019-06-20 | Added | XREF | KEGG_REACTION:R04383 |
2018-07-13 | Deleted | XREF | RHEA:23899 |
2018-07-13 | Added | XREF | RHEA:23896 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity |
2002-02-06 | Updated | TERM | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase |
2001-04-03 | Updated | TERM | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase |
2001-03-30 | Added | TERM | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | 4-deoxy-L-threo-5-hexulose uronate isomerase activity |
2020-10-08 | Deleted | SYNONYM | 4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity |
2020-10-08 | Deleted | SYNONYM | 5-keto-4-deoxyuronate isomerase activity |
2020-10-08 | Added | SYNONYM | 4-deoxy-L-threo-5-hexulose uronate isomerase activity |
2020-10-08 | Added | SYNONYM | 4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity |
2020-10-08 | Added | SYNONYM | 5-keto-4-deoxyuronate isomerase activity |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: 4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. |
2007-11-08 | Added | SYNONYM | 4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity |
2007-11-08 | Added | SYNONYM | 4-deoxy-L-threo-5-hexulose uronate isomerase activity |
2007-09-06 | Added | SYNONYM | 5-keto-4-deoxyuronate isomerase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: 4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016861 (intramolecular oxidoreductase activity, interconverting aldoses and ketoses) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R04383 |
2019-06-20 | Added | XREF | KEGG_REACTION:R04383 |
2018-07-13 | Deleted | XREF | RHEA:23899 |
2018-07-13 | Added | XREF | RHEA:23896 |
2010-10-11 | Added | XREF | KEGG:R04383 |
2010-10-11 | Added | XREF | RHEA:23899 |
2003-10-27 | Added | XREF | MetaCyc:5.3.1.17-RXN |
2001-03-30 | Added | XREF | EC:5.3.1.17 |
Timestamp | Action | Category | Detail |
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